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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000260317

Summary for RP11-48B3.4

check button Gene summary

Gene informationEnsembl ID

ENSG00000260317

Gene symbol

RP11-48B3.4

Gene name
HGNC
Entrez ID
Gene typelincRNA
Synonyms
UniProtAcc

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Structure and expression level for RP11-48B3.4

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002603171.683093e+021.809428e+002.158322e-018.383492e+005.140000e-176.370000e-16UPKICH
ENSG000002603171.460737e+021.186486e+001.625188e-017.300608e+002.860000e-133.180000e-12UPKIRP
ENSG000002603172.660423e+021.263203e+001.173275e-011.076647e+014.960000e-273.130000e-25UPPRAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002603173.974822e-011.147825e-04KICH1.919391e-04
ENSG000002603173.861923e-014.854998e-21PRAD1.288543e-19

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lncRNA-Protein interaction for RP11-48B3.4

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000084093REST51.8293.0412Q13127TF,EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000167967E4F173.9992.3745Q66K89TFNA
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000130254SAFB270.2394.7358Q14151TF,RBPNA
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000099326MZF167.8393.2949P28698TFNA
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000084093REST51.8294.3502Q13127TF,EpiNA
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000198521ZNF4348.0392.1912P17038TFNA
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000170631ZNF1639.1692.5695P17020TFNA
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000147789ZNF738.9492.5286P17097TFNA
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000198040ZNF8438.0793.757P51523TFNA
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000146587RBAK36.791.9771Q9NYW8TFNA
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000164631ZNF1225.9892.5692P17014TFNA
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000167766ZNF837.8692.7703P51522TFNA
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000178177LCORL2.093.1833Q8N3X6TFNA
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000196378ZNF341.4792.572Q8IZ26TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000111641NOP277.794.3247P46087RBPNA
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000130254SAFB270.2394.8616Q14151TF,RBPNA
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000079134THOC144.9790.6261Q96FV9RBPNA
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000135870RC3H144.1394.2437Q5TC82RBPNA
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000129351ILF332.8595.1587Q12906RBPNA
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000184863RBM3318.8893.399Q96EV2RBPNA
ENSG00000260317ENST00000569134RP11-48B3.4ENSG00000164548TRA2A3.9293.5707Q13595RBPNA

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lncRNA-DNA interaction for RP11-48B3.4

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
HSF1,LSM5,ZNF16,NOP2,ILF3,GLI4,THOC6,RC3H1,LCORL,PUF60,TIGD5,MZF1,ZNF43,NRF1,AKAP8,ZNF84,AGO2,CSTF3,CPSF1,RNPS1,DDX51,NR2F6,TRA2A,PURB,MYEF2,ZNF24,NFYC,FOXP1,ZNF83,RALY,USF1,ZNF34,SAFB2,THOC1,RBM33,E2F5
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP11-48B3.4

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000260317ENST00000569134exon_skip_23423chr1:26294204-26294331-13.09-0.1487UBXN11ENST00000374221,ENST00000374222Frame-shift
ENSG00000260317ENST00000569134exon_skip_41813chr10:68337857-68337996-13.00-0.1066HNRNPH3ENST00000265866Frame-shift
ENSG00000260317ENST00000569134exon_skip_382458chr3:38131595-38131638-6.96-0.1933ACAA1ENST00000333167Frame-shift

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for RP11-48B3.4

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000260317.1ENST00000569134.112337353364