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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000259673

Summary for IQCH-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000259673

Gene symbol

IQCH-AS1

Gene nameIQCH antisense RNA 1
HGNC

44104

Entrez ID

100506686

Gene typelincRNA
Synonyms15q23|IQCH-AS1
UniProtAcc

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Structure and expression level for IQCH-AS1

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002596731.143744e+031.017574e+001.270153e-018.011429e+001.130000e-151.220000e-14UPKICH

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002596733.722768e-011.179307e-02CHOL1.363930e-02
ENSG000002596734.082825e-017.132527e-05KICH1.238969e-04

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lncRNA-Protein interaction for IQCH-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000167232ZNF9182.2797.8374Q05481TFNA
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000198521ZNF4381.1697.0802P17038TFNA
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000126804ZBTB178.5797.7217Q9Y2K1TFNA
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000146587RBAK72.5297.0042Q9NYW8TFNA
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000198040ZNF8465.7296.8665P51523TFNA
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000147789ZNF762.6497.3438P17097TFNA
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000164631ZNF1255.2696.2162P17014TFChIP-seq
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000142065ZFP1447.9996.6323Q9HCL3TFNA
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000120784ZFP3047.6596.7777Q9Y2G7TFNA
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000197857ZNF4440.796.6598P15621TFNA
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000166526ZNF332.6296.0206P17036TFChIP-seq
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000062194GPBP131.7292.1392Q86WP2TFNA
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000174738NR1D228.8595.9873Q14995TFNA
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000146757ZNF9224.6996.2401Q03936TFNA
ENSG00000259673ENST00000561232IQCH-AS1ENSG00000126804ZBTB198.1498.1795Q9Y2K1TFNA
ENSG00000259673ENST00000561232IQCH-AS1ENSG00000142065ZFP1490.697.2755Q9HCL3TFNA
ENSG00000259673ENST00000561232IQCH-AS1ENSG00000146587RBAK88.6497.5557Q9NYW8TFNA
ENSG00000259673ENST00000561232IQCH-AS1ENSG00000120784ZFP3088.4497.4211Q9Y2G7TFNA
ENSG00000259673ENST00000561232IQCH-AS1ENSG00000197857ZNF4475.997.8292P15621TFNA
ENSG00000259673ENST00000561232IQCH-AS1ENSG00000198521ZNF4371.8197.8509P17038TFNA
ENSG00000259673ENST00000561232IQCH-AS1ENSG00000164631ZNF1271.7796.7714P17014TFChIP-seq
ENSG00000259673ENST00000561232IQCH-AS1ENSG00000167232ZNF9170.5698.3038Q05481TFNA
ENSG00000259673ENST00000561232IQCH-AS1ENSG00000198040ZNF8465.1697.3186P51523TFNA
ENSG00000259673ENST00000561232IQCH-AS1ENSG00000166526ZNF364.2896.7174P17036TFChIP-seq
ENSG00000259673ENST00000561232IQCH-AS1ENSG00000147789ZNF753.2897.9245P17097TFNA
ENSG00000259673ENST00000561232IQCH-AS1ENSG00000146757ZNF9251.5197.4909Q03936TFNA
ENSG00000259673ENST00000561232IQCH-AS1ENSG00000174738NR1D230.8396.7598Q14995TFNA
ENSG00000259673ENST00000561232IQCH-AS1ENSG00000062194GPBP125.6693.5964Q86WP2TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000259673ENST00000561232IQCH-AS1ENSG00000137776SLTM94.3498.2953Q9NWH9RBPNA
ENSG00000259673ENST00000561232IQCH-AS1ENSG00000124193SRSF685.8797.5073Q13247RBPNA
ENSG00000259673ENST00000561232IQCH-AS1ENSG00000173914RBM4B77.9795.7711Q9BQ04RBPNA
ENSG00000259673ENST00000561232IQCH-AS1ENSG00000106344RBM2875.8298.3227Q9NW13RBPNA
ENSG00000259673ENST00000561232IQCH-AS1ENSG00000135870RC3H161.7897.3336Q5TC82RBPNA
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000137776SLTM105.7498.105Q9NWH9RBPNA
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000106344RBM2891.8197.6275Q9NW13RBPNA
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000135870RC3H170.0397.0279Q5TC82RBPNA
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000173914RBM4B52.6294.7899Q9BQ04RBPNA
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000124193SRSF651.1597.3153Q13247RBPNA
ENSG00000259673ENST00000559298IQCH-AS1ENSG00000143486EIF2D31.394.626P41214RBPNA

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lncRNA-DNA interaction for IQCH-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
CNOT4,DDX59,AQR,GPBP1,PUM1,RBM48,RBM39,EDC3,TTC14,RBM41,DZIP3,RC3H1,ZFP62,ZNF44,ZNF43,MYSM1,ZNF91,ZXDC,ZNF84,RBM4B,DMTF1,KRR1,TIGD1,RBM45,NFXL1,TRA2A,PURB,ADNP,MYEF2,PUS7L,RBM28,NR2C1,ZFP30,MYNN,DDX55,ZFP3,ZMAT1,ZNF83,THAP9,ZFP14,RNPC3,ZNF3,THAP6,THOC1,DDX17,NR2C2,EIF2D
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for IQCH-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for IQCH-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000259673.4ENST00000559298.468374168
ENSG00000259673.4ENST00000561232.4125946569
ENSG00000259673.4ENST00000558025.1118941585
ENSG00000259673.4ENST00000559285.157223396
ENSG00000259673.4ENST00000559702.1136915505