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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000259347

Summary for RP11-798K3.2

check button Gene summary

Gene informationEnsembl ID

ENSG00000259347

Gene symbol

RP11-798K3.2

Gene name
HGNC
Entrez ID
Gene typelincRNA
Synonyms
UniProtAcc

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Structure and expression level for RP11-798K3.2

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002593472.469690e+02-2.589591e+007.747719e-01-3.342391e+008.306000e-042.937445e-03DOWNCHOL
ENSG000002593477.726534e+021.918392e+001.904279e-011.007411e+017.190000e-245.330000e-23UPKIRC

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG00000259347-4.174725e-014.327569e-03CHOL5.767805e-03

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lncRNA-Protein interaction for RP11-798K3.2

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for RP11-798K3.2

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP11-798K3.2

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for RP11-798K3.2

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name
LncEditing_296814ENSG00000259347.4chr1566993437-lincRNARP11-798K3.2ENST00000560662.1lincRNARP11-798K3.2-002
LncEditing_296872ENSG00000259347.4chr1566997277-lincRNARP11-798K3.2ENST00000558097.4lincRNARP11-798K3.2-001
LncEditing_296874ENSG00000259347.4chr1566997279-lincRNARP11-798K3.2ENST00000558097.4lincRNARP11-798K3.2-001
LncEditing_296898ENSG00000259347.4chr1566997354-lincRNARP11-798K3.2ENST00000558097.4lincRNARP11-798K3.2-001
LncEditing_296906ENSG00000259347.4chr1566997693-lincRNARP11-798K3.2ENST00000558097.4lincRNARP11-798K3.2-001
LncEditing_296948ENSG00000259347.4chr1566998968-lincRNARP11-798K3.2ENST00000558097.4lincRNARP11-798K3.2-001
LncEditing_296954ENSG00000259347.4chr1566999295-lincRNARP11-798K3.2ENST00000558097.4lincRNARP11-798K3.2-001
LncEditing_296964ENSG00000259347.4chr1566999335-lincRNARP11-798K3.2ENST00000558097.4lincRNARP11-798K3.2-001
LncEditing_296966ENSG00000259347.4chr1566999336-lincRNARP11-798K3.2ENST00000558097.4lincRNARP11-798K3.2-001
LncEditing_296974ENSG00000259347.4chr1566999375-lincRNARP11-798K3.2ENST00000558097.4lincRNARP11-798K3.2-001
LncEditing_296978ENSG00000259347.4chr1566999392-lincRNARP11-798K3.2ENST00000558097.4lincRNARP11-798K3.2-001
LncEditing_297092ENSG00000259347.4chr1567047800-lincRNARP11-798K3.2ENST00000558071.1lincRNARP11-798K3.2-003

check buttonEdited-associated DElncRNAs in cancer.
Differentially expressed gene
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange
ENSG00000259347LncEditing_297092LIHCchr15_67047800_-2.385193e+011.478862e+011.450077e+005.822825e+005.786111e-099.362979e-09UP
ENSG00000259347LncEditing_296814KIRCchr15_66993437_-2.339751e+011.331749e+011.229963e+007.266863e+003.679327e-136.328102e-13UP
ENSG00000259347LncEditing_296872KIRCchr15_66997277_-2.309214e+011.236943e+011.110344e+001.024505e+011.245646e-244.226096e-24UP
ENSG00000259347LncEditing_296874KIRCchr15_66997279_-2.393574e+011.265902e+011.088138e+009.597820e+008.165271e-222.099238e-21UP
ENSG00000259347LncEditing_296898KIRCchr15_66997354_-2.545912e+011.265252e+019.913182e-019.848564e+006.953042e-231.986965e-22UP
ENSG00000259347LncEditing_296906KIRCchr15_66997693_-2.432844e+011.247984e+011.038374e+009.877648e+005.204002e-231.498672e-22UP
ENSG00000259347LncEditing_296948KIRCchr15_66998968_-2.210565e+011.316436e+011.337295e+007.463546e+008.422454e-141.493528e-13UP
ENSG00000259347LncEditing_296954KIRCchr15_66999295_-2.347202e+011.262735e+011.118081e+009.290792e+001.531441e-203.706386e-20UP
ENSG00000259347LncEditing_296964KIRCchr15_66999335_-2.434840e+011.260660e+011.053021e+009.493223e+002.240000e-215.660953e-21UP
ENSG00000259347LncEditing_296966KIRCchr15_66999336_-2.403612e+011.271494e+011.088519e+009.176648e+004.447200e-201.048975e-19UP
ENSG00000259347LncEditing_296974KIRCchr15_66999375_-2.419033e+011.312371e+011.133459e+007.916933e+002.434400e-154.661751e-15UP
ENSG00000259347LncEditing_296978KIRCchr15_66999392_-2.345685e+011.207132e+011.043378e+001.060331e+012.876268e-261.084806e-25UP
ENSG00000259347LncEditing_297092KIRCchr15_67047800_-1.752608e+011.375085e+012.857286e+003.677729e+002.353202e-042.645127e-04UP

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value
ENSG00000259347LncEditing_297092-3.866777e-014.630904e-036.395058e-03

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000259347.4ENST00000558071.184568314
ENSG00000259347.4ENST00000558097.491459734
ENSG00000259347.4ENST00000560662.1551651