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lncRNA: ENSG00000257702

Summary for LBX2-AS1

Gene summary

Gene information	Ensembl ID	ENSG00000257702
	Gene symbol	LBX2-AS1
	Gene name	LBX2 antisense RNA 1
	HGNC	25136
	Entrez ID	151534
	Gene type	antisense
	Synonyms	02p13.1\|LBX2-AS1
	UniProtAcc

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Structure and expression level for LBX2-AS1

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000257702	1.378242e+02	3.155720e+00	4.531312e-01	6.964252e+00	3.300000e-12	8.720000e-11	UP	GBM
ENSG00000257702	8.863246e+02	-1.746122e+00	2.361541e-01	-7.393995e+00	1.420000e-13	2.890000e-12	DOWN	CHOL
ENSG00000257702	2.103641e+02	1.482656e+00	1.182546e-01	1.253783e+01	4.640000e-36	2.000000e-34	UP	THCA
ENSG00000257702	8.850604e+02	1.300126e+00	1.040978e-01	1.248947e+01	8.520000e-36	1.140000e-34	UP	KIRC
ENSG00000257702	1.945992e+02	-1.042966e+00	3.459048e-01	-3.015181e+00	2.568257e-03	5.750692e-03	DOWN	KICH
ENSG00000257702	3.273683e+02	1.111576e+00	2.222395e-01	5.001701e+00	5.680000e-07	5.370000e-06	UP	BLCA
ENSG00000257702	2.329867e+02	1.259477e+00	1.395165e-01	9.027444e+00	1.760000e-19	3.480000e-18	UP	HNSC
ENSG00000257702	1.347684e+03	1.748169e+00	1.747178e-01	1.000567e+01	1.440000e-23	5.020000e-22	UP	KIRP
ENSG00000257702	2.331252e+02	1.819419e+00	1.964389e-01	9.262012e+00	2.010000e-20	3.360000e-19	UP	UCEC

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000257702	-4.457370e-01	2.150642e-03	CHOL	3.224047e-03
ENSG00000257702	-5.287957e-01	9.992212e-08	KICH	3.853456e-07
ENSG00000257702	3.186948e-01	8.077991e-16	KIRC	3.709281e-15

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lncRNA-Protein interaction for LBX2-AS1

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000257702	ENST00000548978	LBX2-AS1	ENSG00000204371	EHMT2	39.99	95.7258	Q96KQ7	Epi	Predict
ENSG00000257702	ENST00000548978	LBX2-AS1	ENSG00000280789	PAGR1	14.99	92.5363	Q9BTK6	Epi	NA
ENSG00000257702	ENST00000603175	LBX2-AS1	ENSG00000204371	EHMT2	45.06	93.6847	Q96KQ7	Epi	Predict
ENSG00000257702	ENST00000603175	LBX2-AS1	ENSG00000280789	PAGR1	12.22	93.5921	Q9BTK6	Epi	NA
ENSG00000257702	ENST00000548978	LBX2-AS1	ENSG00000156860	FBRS	7.04	90.3619	Q9HAH7	Epi	NA
ENSG00000257702	ENST00000603175	LBX2-AS1	ENSG00000156860	FBRS	8.32	92.4608	Q9HAH7	Epi	NA

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000257702	ENST00000548978	LBX2-AS1	ENSG00000102878	HSF4	16.94	92.0595	Q9ULV5	TF	NA
ENSG00000257702	ENST00000603175	LBX2-AS1	ENSG00000197114	ZGPAT	66.51	90.2114	Q8N5A5	TF,Epi	NA
ENSG00000257702	ENST00000603175	LBX2-AS1	ENSG00000102878	HSF4	19.31	93.3824	Q9ULV5	TF	NA
ENSG00000257702	ENST00000603175	LBX2-AS1	ENSG00000250571	GLI4	13.14	92.1383	P10075	TF	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000257702	ENST00000603175	LBX2-AS1	ENSG00000150316	CWC15	19.82	91.7996	Q9P013	RBP	NA
ENSG00000257702	ENST00000548978	LBX2-AS1	ENSG00000150316	CWC15	22.14	91.3142	Q9P013	RBP	NA

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lncRNA-DNA interaction for LBX2-AS1

lncRNA targets the enhancer region and positively regulates the gene expression.

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for LBX2-AS1

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

Only predicted by lncTar

ECPAS,TFIP11,KATNAL1,METAP1,PAIP2,MYCBP2,PPP2R5C,GTF2I,EIF3L,KTN1,CSNK1A1,SNX29,ATP5F1A,SLC25A12,CPEB4,TTC37,NAF1,RANBP2,SLC25A40,NUP155,KBTBD4,RBMX,STRBP,FRY,EIF3A,CLINT1,MECP2,CYLD,G3BP1,PCCB,TPST2,ATP5F1B,TTBK2,SMARCA2,KIAA1109,MKKS,CLIP1,FAM13B,CEP41,AMN1,CLASP2,IARS1,ATP6V1H,GABARAPL1,UTP15,COPS3,GTPBP10,FAM172A,CDV3,ATXN10,SLC25A5,RNF38,GFM2,RAP1GDS1

Exist in public source

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

lncRNA and exonskipping events positive correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	ORF mutation
ENSG00000257702	ENST00000548978	exon_skip_462972	chr6:152130719-152130778	-12.32	-0.3850	SYNE1	ENST00000367255	Frame-shift
ENSG00000257702	ENST00000548978	exon_skip_84780	chr12:57720098-57720263	-27.41	-0.1713	OS9	ENST00000315970	In-frame
ENSG00000257702	ENST00000548978	exon_skip_334374	chr2:227347225-227347384	-16.55	-0.1313	MFF	ENST00000353339	In-frame
ENSG00000257702	ENST00000548978	exon_skip_141221	chr16:3023473-3023530	-14.10	-0.2712	HCFC1R1	ENST00000574980	In-frame

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000257702	ENST00000548978	exon_skip_371367	chr3:9697710-9697866	-22.96	-0.1640	MTMR14	ENST00000296003	In-frame

lncRNA targets by miRNA.

LncRNA Ensembl ID

miRNA ID

LncRNA ENST ID

Binding site in lncRNA

Score

Energy

Align Len

Public source

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Variants for LBX2-AS1

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID	LncRNA ENST ID	PC Gene Name	PC Gene ID	PC ENST ID	dG	nDG	Cancer with PC gene up-regulation	Cancer with PC gene Down-regulation
ENSG00000257702	ENST00000603175	FRY	ENSG00000073910	ENST00000380217	-0.3420	1600	-	GBM,KIRC,BLCA,KIRP
ENSG00000257702	ENST00000603175	CEP41	ENSG00000106477	ENST00000343969	-0.1037	278	CHOL	-
ENSG00000257702	ENST00000603175	CEP41	ENSG00000106477	ENST00000471201	-0.1075	451	CHOL	-
ENSG00000257702	ENST00000603175	CLIP1	ENSG00000130779	ENST00000540338	-0.3219	1341	KICH	BLCA
ENSG00000257702	ENST00000603175	CLIP1	ENSG00000130779	ENST00000541108	-0.1308	261	KICH	BLCA
ENSG00000257702	ENST00000603175	AMN1	ENSG00000151743	ENST00000536761	-1.1025	5	-	GBM
ENSG00000257702	ENST00000603175	AMN1	ENSG00000151743	ENST00000542781	-0.2352	663	-	GBM
ENSG00000257702	ENST00000603175	STRBP	ENSG00000165209	ENST00000471564	-0.1261	265	KICH	-
ENSG00000257702	ENST00000603175	TPST2	ENSG00000128294	ENST00000445720	-0.1524	527	KICH	KIRP
ENSG00000257702	ENST00000548978	FRY	ENSG00000073910	ENST00000380217	-0.3420	1368	-	GBM,KIRC,BLCA,KIRP
ENSG00000257702	ENST00000548978	CEP41	ENSG00000106477	ENST00000343969	-0.1037	278	CHOL	-
ENSG00000257702	ENST00000548978	CEP41	ENSG00000106477	ENST00000471201	-0.1075	451	CHOL	-
ENSG00000257702	ENST00000548978	CLIP1	ENSG00000130779	ENST00000540338	-0.3219	1109	KICH	BLCA
ENSG00000257702	ENST00000548978	CLIP1	ENSG00000130779	ENST00000541108	-0.1308	261	KICH	BLCA
ENSG00000257702	ENST00000548978	AMN1	ENSG00000151743	ENST00000536761	-1.1025	5	-	GBM
ENSG00000257702	ENST00000548978	AMN1	ENSG00000151743	ENST00000542781	-0.2352	663	-	GBM
ENSG00000257702	ENST00000548978	STRBP	ENSG00000165209	ENST00000471564	-0.1261	265	KICH	-
ENSG00000257702	ENST00000548978	TPST2	ENSG00000128294	ENST00000445720	-0.1524	527	KICH	KIRP
ENSG00000257702	ENST00000603175	TFIP11	ENSG00000100109	ENST00000407431	-0.3544	1600	KICH	-
ENSG00000257702	ENST00000603175	TFIP11	ENSG00000100109	ENST00000407148	-0.3544	1600	KICH	-
ENSG00000257702	ENST00000603175	TFIP11	ENSG00000100109	ENST00000405938	-0.8700	1600	KICH	-
ENSG00000257702	ENST00000603175	SLC25A12	ENSG00000115840	ENST00000426896	-0.1229	812	CHOL	GBM,BLCA,HNSC
ENSG00000257702	ENST00000603175	RAP1GDS1	ENSG00000138698	ENST00000510870	-0.1739	1353	KICH	GBM
ENSG00000257702	ENST00000603175	RAP1GDS1	ENSG00000138698	ENST00000408900	-0.1121	1204	KICH	GBM
ENSG00000257702	ENST00000603175	RAP1GDS1	ENSG00000138698	ENST00000339360	-0.1121	1204	KICH	GBM
ENSG00000257702	ENST00000548978	TFIP11	ENSG00000100109	ENST00000407431	-0.3544	1368	KICH	-
ENSG00000257702	ENST00000548978	TFIP11	ENSG00000100109	ENST00000407148	-0.3544	1368	KICH	-
ENSG00000257702	ENST00000548978	TFIP11	ENSG00000100109	ENST00000405938	-0.8700	1368	KICH	-
ENSG00000257702	ENST00000548978	CLASP2	ENSG00000163539	ENST00000487553	-0.1200	784	-	GBM
ENSG00000257702	ENST00000548978	RAP1GDS1	ENSG00000138698	ENST00000510870	-0.1739	1121	KICH	GBM
ENSG00000257702	ENST00000548978	RAP1GDS1	ENSG00000138698	ENST00000408900	-0.1121	972	KICH	GBM
ENSG00000257702	ENST00000548978	RAP1GDS1	ENSG00000138698	ENST00000339360	-0.1121	972	KICH	GBM
ENSG00000257702	ENST00000603175	ATP6V1H	ENSG00000047249	ENST00000519588	-0.1148	310	-	GBM,KIRC
ENSG00000257702	ENST00000603175	SLC25A40	ENSG00000075303	ENST00000444363	-0.1829	1084	KICH	-
ENSG00000257702	ENST00000603175	MKKS	ENSG00000125863	ENST00000399054	-0.1373	1702	KICH	-
ENSG00000257702	ENST00000603175	GABARAPL1	ENSG00000139112	ENST00000539408	-0.1704	341	KICH	GBM,KIRC,BLCA,UCEC
ENSG00000257702	ENST00000603175	GABARAPL1	ENSG00000139112	ENST00000421801	-0.1112	900	KICH	GBM,KIRC,BLCA,UCEC
ENSG00000257702	ENST00000603175	GABARAPL1	ENSG00000139112	ENST00000544284	-0.2565	565	KICH	GBM,KIRC,BLCA,UCEC
ENSG00000257702	ENST00000603175	GABARAPL1	ENSG00000139112	ENST00000545047	-0.1167	344	KICH	GBM,KIRC,BLCA,UCEC
ENSG00000257702	ENST00000603175	GABARAPL1	ENSG00000139112	ENST00000541453	-0.1385	590	KICH	GBM,KIRC,BLCA,UCEC
ENSG00000257702	ENST00000603175	GABARAPL1	ENSG00000139112	ENST00000543602	-0.1222	1178	KICH	GBM,KIRC,BLCA,UCEC
ENSG00000257702	ENST00000603175	GABARAPL1	ENSG00000139112	ENST00000537201	-0.1279	256	KICH	GBM,KIRC,BLCA,UCEC
ENSG00000257702	ENST00000603175	GABARAPL1	ENSG00000139112	ENST00000545887	-0.2829	546	KICH	GBM,KIRC,BLCA,UCEC
ENSG00000257702	ENST00000603175	ATP5F1A	ENSG00000152234	ENST00000592364	-0.1083	241	-	KIRC,HNSC
ENSG00000257702	ENST00000603175	SMARCA2	ENSG00000080503	ENST00000382186	-2.2800	1213	-	GBM,KIRP,UCEC
ENSG00000257702	ENST00000603175	PCCB	ENSG00000114054	ENST00000251654	-0.1248	336	-	KIRC
ENSG00000257702	ENST00000603175	PCCB	ENSG00000114054	ENST00000490504	-0.1248	336	-	KIRC
ENSG00000257702	ENST00000603175	PCCB	ENSG00000114054	ENST00000483687	-0.1248	336	-	KIRC
ENSG00000257702	ENST00000603175	PCCB	ENSG00000114054	ENST00000468777	-0.1248	336	-	KIRC
ENSG00000257702	ENST00000603175	PCCB	ENSG00000114054	ENST00000462637	-0.1248	336	-	KIRC
ENSG00000257702	ENST00000603175	PCCB	ENSG00000114054	ENST00000466072	-0.1248	336	-	KIRC
ENSG00000257702	ENST00000603175	PCCB	ENSG00000114054	ENST00000482086	-0.1248	336	-	KIRC
ENSG00000257702	ENST00000548978	SLC25A5	ENSG00000005022	ENST00000317881	-0.1238	724	KICH	KIRC
ENSG00000257702	ENST00000548978	ATP6V1H	ENSG00000047249	ENST00000522849	-0.1128	632	-	GBM,KIRC
ENSG00000257702	ENST00000548978	ATP6V1H	ENSG00000047249	ENST00000519588	-0.1148	310	-	GBM,KIRC
ENSG00000257702	ENST00000548978	SLC25A40	ENSG00000075303	ENST00000444363	-0.1829	852	KICH	-
ENSG00000257702	ENST00000548978	MKKS	ENSG00000125863	ENST00000399054	-0.1373	1470	KICH	-
ENSG00000257702	ENST00000548978	GABARAPL1	ENSG00000139112	ENST00000539408	-0.1704	341	KICH	GBM,KIRC,BLCA,UCEC
ENSG00000257702	ENST00000548978	GABARAPL1	ENSG00000139112	ENST00000544284	-0.2565	565	KICH	GBM,KIRC,BLCA,UCEC
ENSG00000257702	ENST00000548978	GABARAPL1	ENSG00000139112	ENST00000545047	-0.1167	344	KICH	GBM,KIRC,BLCA,UCEC
ENSG00000257702	ENST00000548978	GABARAPL1	ENSG00000139112	ENST00000541453	-0.1385	590	KICH	GBM,KIRC,BLCA,UCEC
ENSG00000257702	ENST00000548978	GABARAPL1	ENSG00000139112	ENST00000543602	-0.1222	946	KICH	GBM,KIRC,BLCA,UCEC
ENSG00000257702	ENST00000548978	GABARAPL1	ENSG00000139112	ENST00000537201	-0.1279	256	KICH	GBM,KIRC,BLCA,UCEC
ENSG00000257702	ENST00000548978	GABARAPL1	ENSG00000139112	ENST00000545887	-0.2829	546	KICH	GBM,KIRC,BLCA,UCEC
ENSG00000257702	ENST00000548978	ATP5F1A	ENSG00000152234	ENST00000592364	-0.1083	241	-	KIRC,HNSC
ENSG00000257702	ENST00000548978	SMARCA2	ENSG00000080503	ENST00000382186	-2.2800	981	-	GBM,KIRP,UCEC
ENSG00000257702	ENST00000548978	PCCB	ENSG00000114054	ENST00000251654	-0.1248	336	-	KIRC
ENSG00000257702	ENST00000548978	PCCB	ENSG00000114054	ENST00000490504	-0.1248	336	-	KIRC
ENSG00000257702	ENST00000548978	PCCB	ENSG00000114054	ENST00000483687	-0.1248	336	-	KIRC
ENSG00000257702	ENST00000548978	PCCB	ENSG00000114054	ENST00000468777	-0.1248	336	-	KIRC
ENSG00000257702	ENST00000548978	PCCB	ENSG00000114054	ENST00000462637	-0.1248	336	-	KIRC
ENSG00000257702	ENST00000548978	PCCB	ENSG00000114054	ENST00000466072	-0.1248	336	-	KIRC
ENSG00000257702	ENST00000548978	PCCB	ENSG00000114054	ENST00000482086	-0.1248	336	-	KIRC

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000257702.3	ENST00000603175.1	152	191	646
ENSG00000257702.3	ENST00000548978.2	140	971	549

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential