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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000243069

Summary for ARHGEF26-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000243069

Gene symbol

ARHGEF26-AS1

Gene nameARHGEF26 antisense RNA 1
HGNC

41048

Entrez ID

100507524

Gene typeprocessed_transcript
Synonyms03q25.2|ARHGEF26-AS1
UniProtAcc

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Structure and expression level for ARHGEF26-AS1

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value

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lncRNA-Protein interaction for ARHGEF26-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for ARHGEF26-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for ARHGEF26-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for ARHGEF26-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name
LncEditing_108917ENSG00000243069.6chr3154025764-processed_transcriptARHGEF26-AS1ENST00000491862.4antisenseARHGEF26-AS1-001
LncEditing_109053ENSG00000243069.6chr3154119699-processed_transcriptARHGEF26-AS1ENST00000491862.4antisenseARHGEF26-AS1-001
LncEditing_109065ENSG00000243069.6chr3154119724-processed_transcriptARHGEF26-AS1ENST00000491862.4antisenseARHGEF26-AS1-001
LncEditing_109069ENSG00000243069.6chr3154119725-processed_transcriptARHGEF26-AS1ENST00000491862.4antisenseARHGEF26-AS1-001
LncEditing_109073ENSG00000243069.6chr3154119728-processed_transcriptARHGEF26-AS1ENST00000491862.4antisenseARHGEF26-AS1-001
LncEditing_109077ENSG00000243069.6chr3154119729-processed_transcriptARHGEF26-AS1ENST00000491862.4antisenseARHGEF26-AS1-001
LncEditing_109081ENSG00000243069.6chr3154119736-processed_transcriptARHGEF26-AS1ENST00000491862.4antisenseARHGEF26-AS1-001

check buttonEdited-associated DElncRNAs in cancer.
Differentially expressed gene
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange
ENSG00000243069LncEditing_108917GBMchr3_154025764_-3.393730e+002.452287e+002.133361e+003.279662e+001.039314e-031.279764e-03UP
ENSG00000243069LncEditing_109053GBMchr3_154119699_-3.097043e+001.410443e+008.812568e-017.238564e+004.534609e-134.168748e-12UP
ENSG00000243069LncEditing_109065GBMchr3_154119724_-3.144635e+002.338786e+002.341194e+003.789958e+001.506727e-042.055551e-04UP
ENSG00000243069LncEditing_109069GBMchr3_154119725_-3.194653e+001.431170e+008.632117e-017.934544e+002.112698e-153.974820e-14UP
ENSG00000243069LncEditing_109073GBMchr3_154119728_-3.229910e+001.716165e+001.096124e+006.600638e+004.093924e-112.069990e-10UP
ENSG00000243069LncEditing_109077GBMchr3_154119729_-3.418881e+002.033481e+001.334094e+005.289342e+001.227569e-072.797474e-07UP
ENSG00000243069LncEditing_109081GBMchr3_154119736_-3.787886e+002.364401e+001.470765e+003.227739e+001.247725e-031.522489e-03UP
ENSG00000243069LncEditing_109053LGGchr3_154119699_-5.146376e+003.193031e+001.452158e+001.049754e+018.865912e-263.725794e-25UP
ENSG00000243069LncEditing_109069LGGchr3_154119725_-5.622216e+003.871486e+001.857868e+009.146019e+005.907054e-201.744929e-19UP
ENSG00000243069LncEditing_109073LGGchr3_154119728_-5.653417e+004.020760e+002.033947e+007.914045e+002.491590e-155.235304e-15UP
ENSG00000243069LncEditing_109077LGGchr3_154119729_-5.406171e+004.236140e+002.842063e+005.110044e+003.220840e-074.104536e-07UP

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000243069.6ENST00000491862.4651940
ENSG00000243069.6ENST00000467912.4962870
ENSG00000243069.6ENST00000480639.497151444
ENSG00000243069.6ENST00000479270.473179400
ENSG00000243069.6ENST00000601822.595431144
ENSG00000243069.6ENST00000597231.13715643
ENSG00000243069.6ENST00000611093.340218340
ENSG00000243069.6ENST00000608560.252474632
ENSG00000243069.6ENST00000630930.160393211
ENSG00000243069.6ENST00000621011.29732835
ENSG00000243069.6ENST00000610221.169669460