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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000240291

Summary for RP11-499P20.2

check button Gene summary

Gene informationEnsembl ID

ENSG00000240291

Gene symbol

RP11-499P20.2

Gene name
HGNC
Entrez ID
Gene typeantisense
Synonyms
UniProtAcc

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Structure and expression level for RP11-499P20.2

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002402911.602201e+02-1.633356e+003.364647e-01-4.854465e+001.210000e-067.810000e-06DOWNCHOL
ENSG000002402919.797198e+011.352630e+002.358776e-015.734457e+009.780000e-095.880000e-08UPKIRP

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002402913.046926e-017.053186e-03ACC1.800814e-02

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lncRNA-Protein interaction for RP11-499P20.2

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000240291ENST00000425669RP11-499P20.2ENSG00000162601MYSM166.6992.0354Q5VVJ2TF,EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000240291ENST00000425669RP11-499P20.2ENSG00000162601MYSM166.6992.0154Q5VVJ2TF,EpiNA
ENSG00000240291ENST00000425669RP11-499P20.2ENSG00000141258SGSM250.2892.4455O43147TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for RP11-499P20.2

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
ZNF30,AGAP6,ARHGEF1,ATAT1,GSDMB,PYROXD2,EPOR,GLI4,OVGP1,RBM39,SLC25A27,LENG8,BICRA,SH2B1,CIRBP,C1orf159,DGKA,MZF1,MYSM1,IP6K2,PPOX,MAPK8IP3,N4BP2L2,BCS1L,PPWD1,DMTF1,PIGL,KATNBL1,CSAD,KIAA0895L,LMBR1L,GPCPD1,TRAPPC12,GPATCH2,TBRG1,DCAF8,ULK3,ABCA5,PHYKPL,TMEM259,CCNL2,FRA10AC1,CAPN10,LIN37,AP1G2,CENATAC,NPEPL1,GLMN,CLK3,RNPC3,OGA,ZFP69,SLC6A16,ANKRD10,SAFB2,VPS9D1,MSANTD2,TUBGCP6,ANKMY1,WDR59,THOC1,CCDC14,GABBR1,TMEM175,CLK4,SUPT7L,ZBED5,DDTL,CENPT,TTC14,MC1R,KYAT1,CCNT2,MTG1,SPRN,SUGP1,TAZ,SPG7,ZNF44,POGZ,KAT2A,ACBD4,LTO1,RBM4B,PPIP5K1,ECHDC2,METAP1D,OGT,ANAPC2,RBM26,PLA2G6,TAF1C,CLK2,ADAT2,MYEF2,RBM25,LCAT,POLG2,DHX34,IFT80,CHKB,METTL17,SETD6,POLI,CAPN15,CNKSR1,OSGEP,EXD3,CTC1,CLK1,PRPF39,CXXC1,MRRF,MRNIP,ERMARD,RABL2A,ELMOD3,TRIM45,OFD1,DDX17,PCED1A,ACYP1,GSTM2,SLC25A29,MIB2,HAUS5,FCHSD1,MTRF1,IFT172,RAD52,PHF1,DYNLT2,ACIN1,ZC3H8,HDAC10,HSF4,ENOSF1,ANKS3,ARGLU1,NOXA1,YJEFN3,ANKRD49,C3orf62,PAXBP1,CCNL1,RGL3,SGSM2,FNBP4,INPP5E,POLL,ORMDL1,FAM228B,RSRP1,TIGD1,RBM45,HSPBAP1,CRYGS,YAE1,CHD2,AGER,GPS2,TRIM52,LBHD1,NOL12,CLEC2D,SPOUT1,EGFL8,CLASRP,SRSF2,TTC13,CDK11A,FIZ1,STK36,TTC32,LTB4R,KIFC2,TSNARE1,TIA1,ZMAT1,ZNF83,ATG4B,GOLGA8B,HEMK1,NSUN6,CCDC191,LMNTD2,NXF1,STRADA,ZNF18,LZTS2,PAN2,CLHC1,GOLGA8A,FAM229A,SETD4,NEIL1,NDUFAF7,RBM6,SZT2,GIGYF1,TRMT13,ADAMTS13,ZNF862,FAM193B,IDUA,AARSD1,DUSP28,SLC25A28,SEC31B,RBM5,NKTR,MYL5,LUC7L,KLHL17,ARHGAP33,MBTD1,PNN,COA5,DNASE1,LUC7L2,TTLL3,HEXD,ZNF84,CCAR1,C14orf93,VCPKMT,PARP6,DPH7,SCNN1D,C19orf18,CCDC24,TRA2A,WDR27,EME2,DUS1L,HINFP,KHDC4,NR2C1,LRP5L,PLXNB1,CROCC,APBB3,RSAD1,AMY2B,TSC1,ERCC5,SH3GLB2,EP400P1,CYTH2,PNISR,SFPQ,MAN2C1,DXO,AMT,ACAP3,USPL1,LRRC27,CARD8,WBP1,CCDC57,TRAPPC2,TEPSIN,RBM33,SIRT7,HERC4,NADSYN1,CFAP44,ZNF10
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.
Only predicted by TDF
DCAF8,ADAMTS13,DPH7,C14orf93,TNFRSF25,GTF2H4,ZNF18,ZMAT1,HAUS5,KAT2A,RAD52,LMBR1L,EFHC1,ZNF30,CTC1,PNN,TRA2A,ABCA5,STX16,HSPBAP1,HEMK1,DDX17,SH3GLB2,EP400NL,TIA1,RBM5,E4F1,FAM73B,KPNA5,C9orf114,SLC6A16,RGL3,SETD6,LRRC27,ZNF83,LBHD1,ENOSF1,FRA10AC1,HERC4,OSGEP,CLASRP,TCTE3,LUC7L,MAPK8IP3,CCDC66,MZF1,RAD9A,C3orf62,CXXC1,QTRT1,MYL5,PAXBP1,KIAA0907,SRSF5,STRADA,TRAF5,METTL22,SETD4,POGZ,ACCS,ENGASE,C19orf18,GGA1,CCDC130,GSTM2,CYTH2,ING5,STK36,TBRG1,MTRF1,CCNL1,MAN2C1,AARSD1,PRKRIP1,CARD8,RBM6,ERMARD,ARGLU1,RBM39,AP4B1,MDM4,CIRBP,TAZ
Exist in public source
NA

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP11-499P20.2

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
YIPF5,RNH1,PSMC1,RAB5C,SSR3,SURF4,EIF4G1,RAB7A,HSPA8
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000240291ENST00000436485exon_skip_1234chr1:11658532-11658628-16.18-0.2157FBXO44ENST00000251547,ENST00000376770In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000240291ENST00000436485exon_skip_41813chr10:68337857-68337996-17.60-0.1294HNRNPH3ENST00000265866Frame-shift
ENSG00000240291ENST00000436485exon_skip_370518chr22:50247691-50247776-16.75-0.2175HDAC10ENST00000216271Frame-shift
ENSG00000240291ENST00000436485exon_skip_382458chr3:38131595-38131638-10.60-0.3926ACAA1ENST00000333167Frame-shift
ENSG00000240291ENST00000425669exon_skip_387016chr3:121788283-121788432-14.25-0.1071IQCB1ENST00000310864Frame-shift
ENSG00000240291ENST00000436485exon_skip_442657chr5:74730259-74730398-10.10-0.1020GFM2ENST00000296805,ENST00000509430Frame-shift
ENSG00000240291ENST00000436485exon_skip_470226chr7:103307595-103307708-13.10-0.1541PMPCBENST00000249269Frame-shift

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for RP11-499P20.2

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation
ENSG00000240291ENSG00000108773KAT2AACC,BLCA,BRCA,DLBC,KIRP,LGG,LIHC,TGCT,THYM,UCEC,UCSKIRP
ENSG00000240291ENSG00000132522GPS2ACC,BLCA,BRCA,CHOL,DLBC,KIRP,LGG,TGCT,THYM,UCEC,UCSKIRP
ENSG00000240291ENSG00000139631CSADACC,BLCA,BRCA,CHOL,DLBC,KIRP,LGG,TGCT,UCEC,UCSCHOL
ENSG00000240291ENSG00000175455CCDC14ACC,BLCA,BRCA,DLBC,KIRP,LAML,LGG,LIHC,TGCT,THYM,UCEC,UCSKIRP
ENSG00000240291ENSG00000184465WDR27ACC,BRCA,DLBC,KIRP,LAML,LGG,TGCT,UCEC,UCSKIRP
ENSG00000240291ENSG00000186166CENATACACC,BLCA,BRCA,KIRP,LGG,THYM,UCEC,UCSKIRP
ENSG00000240291ENSG00000196123KIAA0895LACC,BLCA,BRCA,DLBC,KIRP,LGG,TGCT,THYM,UCEC,UCSKIRP
ENSG00000240291ENSG00000197948FCHSD1ACC,BLCA,BRCA,DLBC,KIRP,TGCT,UCSKIRP
ENSG00000240291ENSG00000204149AGAP6ACC,BLCA,BRCA,DLBC,KIRP,LGG,LIHC,TGCT,THYM,UCEC,UCSKIRP
ENSG00000240291ENSG00000204305AGERACC,BLCA,BRCA,CHOL,DLBC,KIRP,LGG,TGCT,UCEC,UCSKIRP
ENSG00000240291ENSG00000204681GABBR1ACC,BRCA,DLBC,KIRP,UCEC,UCSKIRP
ENSG00000240291ENSG00000213398LCATACC,BLCA,BRCA,KIRP,TGCT,UCEC,UCSKIRP
ENSG00000240291ENSG00000214021TTLL3ACC,BLCA,BRCA,KIRP,LGG,TGCT,THYM,UCEC,UCSKIRP
ENSG00000240291ENSG00000221978CCNL2ACC,BLCA,BRCA,CHOL,DLBC,KIRP,LGG,LIHC,TGCT,THYM,UCEC,UCSKIRP
ENSG00000240291ENSG00000250067YJEFN3ACC,DLBC,KIRP,LAML,LGG,TGCT,THYM,UCEC,UCSKIRP
ENSG00000240291ENSG00000258839MC1RACC,KIRP,LGG,TGCT,THYM,UCECKIRP
ENSG00000240291ENSG00000065357DGKABLCA,DLBC,KIRP,LGG,TGCTKIRP
ENSG00000240291ENSG00000073605GSDMBBLCA,DLBC,KIRP,LGG,LIHC,TGCT,THYM,UCSKIRP
ENSG00000240291ENSG00000099974DDTLBLCA,BRCA,CHOL,DLBC,KIRP,LGG,LIHC,THYMCHOL
ENSG00000240291ENSG00000100429HDAC10BLCA,BRCA,KIRP,LGG,TGCT,UCECKIRP
ENSG00000240291ENSG00000121310ECHDC2BLCA,BRCA,CHOL,KIRP,UCEC,UCSCHOL
ENSG00000240291ENSG00000127415IDUABLCA,BRCA,KIRP,LGG,UCECKIRP
ENSG00000240291ENSG00000138834MAPK8IP3BLCA,BRCA,DLBC,KIRP,TGCT,UCEC,UCSKIRP
ENSG00000240291ENSG00000145020AMTBLCA,BRCA,CHOL,DLBC,KIRPCHOL
ENSG00000240291ENSG00000162194LBHD1BLCA,DLBC,KIRP,THYM,UCEC,UCSKIRP
ENSG00000240291ENSG00000167702KIFC2BLCA,KIRP,TGCT,THYM,UCECKIRP
ENSG00000240291ENSG00000168096ANKS3BLCA,BRCA,DLBC,KIRP,LGG,UCEC,UCSKIRP
ENSG00000240291ENSG00000175265GOLGA8ABLCA,BRCA,DLBC,KIRP,LGG,TGCT,UCEC,UCSKIRP
ENSG00000240291ENSG00000181513ACBD4BLCA,BRCA,CHOL,DLBC,KIRP,UCSCHOL
ENSG00000240291ENSG00000197774EME2BLCA,BRCA,DLBC,KIRP,LGG,THYM,UCECKIRP
ENSG00000240291ENSG00000213139CRYGSBLCA,CHOL,DLBC,KIRP,TGCT,UCECKIRP
ENSG00000240291ENSG00000215252GOLGA8BBLCA,BRCA,CHOL,DLBC,KIRP,LGG,LIHC,TGCT,THYM,UCEC,UCSKIRP
ENSG00000240291ENSG00000215375MYL5BLCA,BRCA,DLBC,KIRP,LGG,UCECKIRP
ENSG00000240291ENSG00000069493CLEC2DBRCA,DLBC,KIRP,LGG,TGCT,THYM,UCEC,UCSKIRP
ENSG00000240291ENSG00000102125TAZBRCA,DLBC,KIRP,LGG,THYM,UCEC,UCSKIRP
ENSG00000240291ENSG00000135473PAN2BRCA,CHOL,DLBC,KIRP,LGG,TGCT,UCEC,UCSCHOL
ENSG00000240291ENSG00000162572SCNN1DBRCA,CHOL,KIRP,LGG,TGCT,THYMKIRPCHOL
ENSG00000240291ENSG00000213903LTB4RBRCA,CHOL,DLBC,KIRP,LGG,TGCT,UCEC,UCSKIRP
ENSG00000240291ENSG00000063127SLC6A16CHOL,DLBC,KIRP,TGCT,UCSCHOL
ENSG00000240291ENSG00000154265ABCA5CHOL,KIRP,LAML,LIHC,UCSCHOL
ENSG00000240291ENSG00000240038AMY2BCHOL,KIRP,LAML,LGG,THYMKIRP
ENSG00000240291ENSG00000256525POLG2DLBC,KIRP,LGG,THYM,UCSKIRP
ENSG00000240291ENSG00000160323ADAMTS13KIRP,LGG,THYM,UCEC,UCSKIRP
ENSG00000240291ENSG00000241404EGFL8KIRP,LAML,LGG,TGCT,UCSKIRP

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types
ENSG00000240291ENSG00000141258SGSM2ENSG00000132716DCAF85BRCA,DLBC,KIRP,TGCT,THYM
ENSG00000240291ENSG00000141258SGSM2ENSG00000148399DPH75BLCA,BRCA,DLBC,KIRP,UCEC
ENSG00000240291ENSG00000141258SGSM2ENSG00000166432ZMAT15BRCA,KIRP,PRAD,TGCT,THYM
ENSG00000240291ENSG00000141258SGSM2ENSG00000108773KAT2A7BLCA,BRCA,DLBC,KIRP,LGG,TGCT,UCEC
ENSG00000240291ENSG00000141258SGSM2ENSG00000096093EFHC15BLCA,BRCA,DLBC,KIRP,TGCT
ENSG00000240291ENSG00000141258SGSM2ENSG00000100201DDX175BRCA,DLBC,KIRP,PRAD,THYM
ENSG00000240291ENSG00000141258SGSM2ENSG00000185684EP400P15BLCA,BRCA,DLBC,LGG,UCEC
ENSG00000240291ENSG00000141258SGSM2ENSG00000116001TIA15BLCA,DLBC,KIRP,TGCT,THYM
ENSG00000240291ENSG00000141258SGSM2ENSG00000003756RBM58BLCA,BRCA,DLBC,KIRP,LGG,PRAD,TGCT,UCEC
ENSG00000240291ENSG00000162601MYSM1ENSG00000003756RBM55BRCA,KIRP,LAML,LGG,PCPG
ENSG00000240291ENSG00000141258SGSM2ENSG00000167967E4F15BLCA,DLBC,KIRP,LGG,PRAD
ENSG00000240291ENSG00000141258SGSM2ENSG00000148343MIGA25BLCA,DLBC,KIRP,LGG,UCEC
ENSG00000240291ENSG00000141258SGSM2ENSG00000167766ZNF837BLCA,BRCA,DLBC,KIRP,PRAD,TGCT,UCEC
ENSG00000240291ENSG00000141258SGSM2ENSG00000132199ENOSF15BLCA,BRCA,KIRP,TGCT,UCEC
ENSG00000240291ENSG00000141258SGSM2ENSG00000104859CLASRP7BLCA,BRCA,DLBC,KIRP,LGG,THYM,UCEC
ENSG00000240291ENSG00000141258SGSM2ENSG00000007392LUC7L7BLCA,BRCA,DLBC,KIRP,LGG,THYM,UCEC
ENSG00000240291ENSG00000141258SGSM2ENSG00000138834MAPK8IP36BLCA,BRCA,DLBC,KIRP,TGCT,UCEC
ENSG00000240291ENSG00000141258SGSM2ENSG00000099326MZF19BLCA,BRCA,DLBC,KIRP,LGG,PRAD,TGCT,THYM,UCEC
ENSG00000240291ENSG00000141258SGSM2ENSG00000188315C3orf625BLCA,BRCA,KIRP,TGCT,UCEC
ENSG00000240291ENSG00000141258SGSM2ENSG00000154832CXXC15BLCA,BRCA,DLBC,KIRP,PRAD
ENSG00000240291ENSG00000141258SGSM2ENSG00000100650SRSF57BLCA,BRCA,DLBC,KIRP,LGG,PRAD,THYM
ENSG00000240291ENSG00000141258SGSM2ENSG00000167280ENGASE7BLCA,BRCA,DLBC,KIRP,LGG,THYM,UCEC
ENSG00000240291ENSG00000141258SGSM2ENSG00000104957CCDC1306BLCA,BRCA,DLBC,KIRP,THYM,UCEC
ENSG00000240291ENSG00000141258SGSM2ENSG00000163482STK365BLCA,BRCA,KIRP,TGCT,UCEC
ENSG00000240291ENSG00000141258SGSM2ENSG00000140400MAN2C15BLCA,BRCA,KIRP,LGG,UCEC
ENSG00000240291ENSG00000141258SGSM2ENSG00000004534RBM68BLCA,BRCA,DLBC,KIRP,LGG,PRAD,THYM,UCEC
ENSG00000240291ENSG00000141258SGSM2ENSG00000130023ERMARD6BLCA,BRCA,DLBC,KIRP,THYM,UCEC
ENSG00000240291ENSG00000141258SGSM2ENSG00000134884ARGLU17BLCA,BRCA,DLBC,KIRP,LGG,TGCT,THYM

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000240291.1ENST00000425669.198758462
ENSG00000240291.1ENST00000436485.1130702310