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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000237976

Summary for RFX5-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000237976

Gene symbol

RFX5-AS1

Gene nameRFX5 antisense RNA 1
HGNC

40503

Entrez ID
Gene typeantisense
Synonyms01q21.3|RFX5-AS1|RP11-126K1.6
UniProtAcc

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Structure and expression level for RFX5-AS1

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002379761.832380e+022.718162e+003.429862e-017.924988e+002.280000e-151.010000e-13UPGBM
ENSG000002379765.617286e+011.802976e+001.805566e-019.985655e+001.760000e-233.710000e-22UPUCEC

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002379763.094693e-011.707033e-14UCEC1.457691e-13

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lncRNA-Protein interaction for RFX5-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for RFX5-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RFX5-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
CNOT1,PREPL,IDH3A,GSK3B,VPS26C,ITSN1,UTP20,RNF123,NT5C2,ZMYND11,REV1,FRS2,BECN1,DUSP3,KHNYN,ARHGAP26,SMARCC2,QTRT2,TACC1,SECISBP2L,SEPTIN10,SNX6,SPIRE1,LARP1,NPEPPS,KIAA1109,PTPN11,RIOK3,MCM3AP,TBC1D15,ITGB1,PLEKHB2,HECTD1,CUL4A,SUCLG2,PDXDC1,PKN2,KLHL21,FNDC3A,DNAJC11,NR2C2,VPS13B,SEC24B,CLTC,ANKRD11,AP1AR,MFN1,ATRN,ATP2A2,FAM91A1,ALG12,WASF2,SON,KMT2D,CTNNB1,NBR1,VGLL4,FKTN,NUMB,RIC1,CCDC47,PRRC2C,PDPK1,KTN1,M6PR,C5orf24,RAPGEF2,AP3D1,ACBD5,PKD2,APAF1,WWP1,CDYL,RNF111,PCNX1,SNRK,USP32,IQGAP1,RAB29,ACOX1,TMCO3,SMARCA2,KIF13A,SLMAP,RNF31,CLIP1,CMTR2,ARNT,SNTB2,USP12,FBXO11,SLC25A24,ASPH,MINK1,STK24,UBE3C,MKLN1,C9orf64,ARHGAP5,CLCC1,BCL2L2,ITSN2,ASXL2,THAP6,MFSD14A,ROCK1,RNF169,KLF13,UBN1,POLR2B,COPB2,WIPF2,TBC1D2B,UTRN,RAB11FIP1,BAZ2A,SSR1,LARP4,NIPA2,MAST4,MYOF,USP9X,ROCK2,HSPG2,PDLIM5,ASH1L,DYNC1LI2,SLC35A5,RAB18,MIDEAS,RASA1,TNS1,DNAJC13,TGFBRAP1,ARL1,RREB1,C16orf70,VPS50,MED13,WNK1,WDR7,UBXN4,PHC3,COG6,AZI2,TAF6,ATP11A,GOLGA2,DOCK9,SYNJ1,PPARA,TRIP12,GPATCH8,TBC1D23,AKAP10,PDCD6IP,ZC3H7B,GTF2A1,NPC1,MPHOSPH8,SEC23B,NFAT5,DHX15,EIF3L,HBP1,NEK7,CD46,SPTLC1,RO60,CUL2,SMG8,CAB39,ATP1A1,GOSR1,TTC37,PRKAR1A,BIRC6,CALU,DCAF17,ELF1,BACH1,MOSPD2,SPART,AFF1,PIGO,ZZEF1,GCC2,TAF2,OSMR,MRTFB,CAST,TEX2,SNX18,ITFG1,C6orf89,HEATR5A,ITCH,CALCOCO2,RUSF1,IPO7,CANX,FNDC3B,SPG11,DHX36,FYCO1,ZDHHC7,IBTK,NDUFS1,SLC39A6,NOMO2,SCAF11
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000237976ENST00000455503exon_skip_445390chr5:150403120-150403312-20.57-0.2188CD74ENST00000009530In-frame

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for RFX5-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation
ENSG00000237976ENST00000455503GCC2ENSG00000135968ENST00000614209-0.2264376-GBM
ENSG00000237976ENST00000455503TEX2ENSG00000136478ENST00000583501-0.200539-GBM
ENSG00000237976ENST00000455503KIAA1109ENSG00000138688ENST00000419325-0.3269204-GBM
ENSG00000237976ENST00000455503KIAA1109ENSG00000138688ENST00000442707-0.5767177-GBM
ENSG00000237976ENST00000455503PDPK1ENSG00000140992ENST00000441549-0.29721-GBM
ENSG00000237976ENST00000455503PDPK1ENSG00000140992ENST00000492021-0.10841-GBM
ENSG00000237976ENST00000455503PDPK1ENSG00000140992ENST00000389224-0.20241-GBM
ENSG00000237976ENST00000455503NPC1ENSG00000141458ENST00000586150-0.491248-GBM
ENSG00000237976ENST00000455503MINK1ENSG00000141503ENST00000577021-0.10201-GBM
ENSG00000237976ENST00000455503MINK1ENSG00000141503ENST00000576037-0.14351-GBM
ENSG00000237976ENST00000455503ARHGAP26ENSG00000145819ENST00000424007-0.16421-GBM
ENSG00000237976ENST00000455503LARP1ENSG00000155506ENST00000518892-0.17141-GBM
ENSG00000237976ENST00000455503LARP1ENSG00000155506ENST00000518677-0.10771-GBM
ENSG00000237976ENST00000455503RNF123ENSG00000164068ENST00000327697-0.10441-GBM
ENSG00000237976ENST00000455503RNF123ENSG00000164068ENST00000432042-0.1660117-GBM
ENSG00000237976ENST00000455503RNF123ENSG00000164068ENST00000443204-0.13361-GBM
ENSG00000237976ENST00000455503RNF123ENSG00000164068ENST00000433785-0.10441-GBM
ENSG00000237976ENST00000455503ANKRD11ENSG00000167522ENST00000563291-0.21381-GBM
ENSG00000237976ENST00000455503KMT2DENSG00000167548ENST00000526209-0.14203-GBM
ENSG00000237976ENST00000455503USP32ENSG00000170832ENST00000300896-0.11941-GBM
ENSG00000237976ENST00000455503USP32ENSG00000170832ENST00000592339-0.11941-GBM
ENSG00000237976ENST00000455503USP32ENSG00000170832ENST00000593071-0.11943-GBM
ENSG00000237976ENST00000455503USP32ENSG00000170832ENST00000589552-0.10381-GBM
ENSG00000237976ENST00000455503USP32ENSG00000170832ENST00000590297-0.111337-GBM
ENSG00000237976ENST00000455503MRTFBENSG00000186260ENST00000574045-0.1750283-GBM
ENSG00000237976ENST00000455503MRTFBENSG00000186260ENST00000571770-0.17581-GBM
ENSG00000237976ENST00000455503MPHOSPH8ENSG00000196199ENST00000414242-0.1298374-GBM
ENSG00000237976ENST00000455503ITSN2ENSG00000198399ENST00000449392-0.116939-GBM
ENSG00000237976ENST00000455503MAST4ENSG00000069020ENST00000406374-0.2257584-GBM,UCEC
ENSG00000237976ENST00000455503MAST4ENSG00000069020ENST00000432817-0.171829-GBM,UCEC
ENSG00000237976ENST00000455503MAST4ENSG00000069020ENST00000434115-0.2257584-GBM,UCEC
ENSG00000237976ENST00000455503MAST4ENSG00000069020ENST00000411628-0.171829-GBM,UCEC
ENSG00000237976ENST00000455503MAST4ENSG00000069020ENST00000403666-0.124826-GBM,UCEC
ENSG00000237976ENST00000455503MAST4ENSG00000069020ENST00000450827-0.176229-GBM,UCEC
ENSG00000237976ENST00000455503MAST4ENSG00000069020ENST00000407621-0.2257584-GBM,UCEC
ENSG00000237976ENST00000455503MAST4ENSG00000069020ENST00000447738-0.14461-GBM,UCEC
ENSG00000237976ENST00000455503MAST4ENSG00000069020ENST00000443808-0.124826-GBM,UCEC
ENSG00000237976ENST00000455503DOCK9ENSG00000088387ENST00000627024-0.14301-GBM
ENSG00000237976ENST00000455503DOCK9ENSG00000088387ENST00000427887-0.14301-GBM
ENSG00000237976ENST00000455503ROCK2ENSG00000134318ENST00000401753-0.11621-GBM,UCEC
ENSG00000237976ENST00000455503TACC1ENSG00000147526ENST00000520340-0.1549540-GBM,UCEC
ENSG00000237976ENST00000455503TACC1ENSG00000147526ENST00000518415-0.15074-GBM,UCEC
ENSG00000237976ENST00000455503TACC1ENSG00000147526ENST00000520973-0.12031-GBM,UCEC
ENSG00000237976ENST00000455503TACC1ENSG00000147526ENST00000521866-0.15071-GBM,UCEC
ENSG00000237976ENST00000455503USP12ENSG00000152484ENST00000612674-0.11141-GBM
ENSG00000237976ENST00000455503NOMO2ENSG00000185164ENST00000330537-0.14661-GBM
ENSG00000237976ENST00000455503NOMO2ENSG00000185164ENST00000620440-0.14661-GBM
ENSG00000237976ENST00000455503NOMO2ENSG00000185164ENST00000381474-0.259666-GBM
ENSG00000237976ENST00000455503NOMO2ENSG00000185164ENST00000622306-0.14661-GBM
ENSG00000237976ENST00000455503NOMO2ENSG00000185164ENST00000621364-0.233162-GBM
ENSG00000237976ENST00000455503NOMO2ENSG00000185164ENST00000543392-0.298273-GBM
ENSG00000237976ENST00000455503NOMO2ENSG00000185164ENST00000567831-0.20131-GBM
ENSG00000237976ENST00000455503NOMO2ENSG00000185164ENST00000569051-0.11271-GBM
ENSG00000237976ENST00000455503ITSN1ENSG00000205726ENST00000399353-0.315415-GBM
ENSG00000237976ENST00000455503ITSN1ENSG00000205726ENST00000399367-0.12111-GBM
ENSG00000237976ENST00000455503ITSN1ENSG00000205726ENST00000399338-0.270915-GBM
ENSG00000237976ENST00000455503ITSN1ENSG00000205726ENST00000420666-0.1627436-GBM
ENSG00000237976ENST00000455503SMARCA2ENSG00000080503ENST00000382186-2.0500587-GBM,UCEC
ENSG00000237976ENST00000455503ATRNENSG00000088812ENST00000446916-0.1254122-GBM
ENSG00000237976ENST00000455503WDR7ENSG00000091157ENST00000589935-0.186624-GBM
ENSG00000237976ENST00000455503HECTD1ENSG00000092148ENST00000554471-0.10534-GBM
ENSG00000237976ENST00000455503PCNX1ENSG00000100731ENST00000555780-0.13726-GBM
ENSG00000237976ENST00000455503DUSP3ENSG00000108861ENST00000590753-0.11741-GBM
ENSG00000237976ENST00000455503PRKAR1AENSG00000108946ENST00000586397-0.18261-GBM
ENSG00000237976ENST00000455503C16orf70ENSG00000125149ENST00000569277-0.13461-GBM
ENSG00000237976ENST00000455503BCL2L2ENSG00000129473ENST00000556599-0.276741-GBM,UCEC

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript