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lncRNA: ENSG00000235314

Summary for LINC00957

Gene summary

Gene information	Ensembl ID	ENSG00000235314
	Gene symbol	LINC00957
	Gene name	long intergenic non-protein coding RNA 957
	HGNC	22332
	Entrez ID
	Gene type	lincRNA
	Synonyms	07p13\|LINC00957
	UniProtAcc

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Structure and expression level for LINC00957

AS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000235314	2.854953e+02	-2.116440e+00	4.479433e-01	-4.724796e+00	2.300000e-06	1.730000e-05	DOWN	GBM
ENSG00000235314	1.996093e+02	1.279286e+00	3.910843e-01	3.271126e+00	1.071203e-03	3.681984e-03	UP	CHOL
ENSG00000235314	1.640522e+03	2.122790e+00	1.774306e-01	1.196406e+01	5.480000e-33	2.580000e-31	UP	KICH
ENSG00000235314	1.311116e+03	1.978972e+00	3.268258e-01	6.055128e+00	1.400000e-09	9.910000e-08	UP	PCPG
ENSG00000235314	1.790493e+02	-1.331107e+00	1.684677e-01	-7.901262e+00	2.760000e-15	8.700000e-14	DOWN	STAD

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000235314	4.220335e-01	3.881114e-03	CHOL	5.239193e-03
ENSG00000235314	5.369661e-01	5.803883e-08	KICH	2.425587e-07

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lncRNA-Protein interaction for LINC00957

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

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lncRNA-DNA interaction for LINC00957

lncRNA targets the enhancer region and positively regulates the gene expression.

lncRNA targets the promoter region and positively regulates the gene expression.

Only predicted by TDF

MYPOP,PBX3,JAZF1

Exist in public source

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for LINC00957

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

Only predicted by lncTar

ILF2,TGIF1

Exist in public source

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

lncRNA and exonskipping events positive correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	ORF mutation
ENSG00000235314	ENST00000441052	exon_skip_462554	chr6:136267028-136267175	-14.97	-0.1207	BCLAF1	ENST00000531224	In-frame
ENSG00000235314	ENST00000441052	exon_skip_315518	chr19:12765828-12765834	-3.52	-0.8800	HOOK2	ENST00000397668	In-frame
ENSG00000235314	ENST00000441052	exon_skip_51046	chr10:73439871-73439901	-8.61	-0.4532	PPP3CB	ENST00000360663	In-frame

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000235314	ENST00000441052	exon_skip_13833	chr1:167776063-167776166	-15.46	-0.1645	MPZL1	ENST00000359523	Frame-shift

lncRNA targets by miRNA.

LncRNA Ensembl ID	miRNA ID	LncRNA ENST ID	Binding site in lncRNA	Score	Energy	Align Len	Public source
ENSG00000235314	hsa-mir-455	ENST00000416824	chr7:44039471-44039571	235.00	-99.33	95	NA
ENSG00000235314	hsa-mir-455	ENST00000416824	chr7:44040126-44040213	227.00	-99.26	97	NA
ENSG00000235314	hsa-mir-455	ENST00000416824	chr7:44039231-44039331	206.00	-83.38	97	NA
ENSG00000235314	hsa-mir-455	ENST00000416824	chr7:44039715-44039807	194.00	-94.59	95	NA
ENSG00000235314	hsa-mir-455	ENST00000416824	chr7:44039893-44039989	171.00	-97.70	68	NA
ENSG00000235314	hsa-mir-455	ENST00000416824	chr7:44039606-44039695	170.00	-96.52	93	NA
ENSG00000235314	hsa-mir-455	ENST00000416824	chr7:44040387-44040483	168.00	-87.38	96	NA
ENSG00000235314	hsa-mir-455	ENST00000416824	chr7:44039354-44039450	154.00	-84.80	96	NA
ENSG00000235314	hsa-mir-455	ENST00000416824	chr7:44040003-44040092	144.00	-101.21	87	NA
ENSG00000235314	hsa-mir-455	ENST00000441052	chr7:44039887-44039987	235.00	-99.33	95	NA
ENSG00000235314	hsa-mir-455	ENST00000441052	chr7:44040542-44040629	227.00	-99.26	97	NA
ENSG00000235314	hsa-mir-455	ENST00000441052	chr7:44041650-44041752	208.00	-90.46	100	NA
ENSG00000235314	hsa-mir-455	ENST00000441052	chr7:44042002-44042093	204.00	-90.18	88	NA
ENSG00000235314	hsa-mir-455	ENST00000441052	chr7:44041041-44041144	197.00	-87.22	91	NA
ENSG00000235314	hsa-mir-455	ENST00000441052	chr7:44041285-44041371	197.00	-84.52	86	NA
ENSG00000235314	hsa-mir-455	ENST00000441052	chr7:44039548-44039637	196.00	-92.12	96	NA
ENSG00000235314	hsa-mir-455	ENST00000441052	chr7:44040131-44040223	194.00	-94.59	95	NA
ENSG00000235314	hsa-mir-455	ENST00000441052	chr7:44039653-44039747	193.00	-84.31	87	NA
ENSG00000235314	hsa-mir-455	ENST00000441052	chr7:44041799-44041886	184.00	-87.26	95	NA
ENSG00000235314	hsa-mir-455	ENST00000441052	chr7:44040309-44040405	171.00	-97.70	68	NA
ENSG00000235314	hsa-mir-455	ENST00000441052	chr7:44040022-44040111	170.00	-96.52	93	NA
ENSG00000235314	hsa-mir-455	ENST00000441052	chr7:44040803-44040899	168.00	-87.38	96	NA
ENSG00000235314	hsa-mir-455	ENST00000441052	chr7:44041883-44041979	166.00	-69.43	92	NA
ENSG00000235314	hsa-mir-455	ENST00000441052	chr7:44041180-44041265	165.00	-71.52	94	NA
ENSG00000235314	hsa-mir-455	ENST00000441052	chr7:44041551-44041648	156.00	-72.52	93	NA
ENSG00000235314	hsa-mir-455	ENST00000441052	chr7:44041418-44041511	155.00	-71.49	97	NA
ENSG00000235314	hsa-mir-455	ENST00000441052	chr7:44039770-44039866	154.00	-84.80	96	NA
ENSG00000235314	hsa-mir-455	ENST00000441052	chr7:44040419-44040508	144.00	-101.21	87	NA

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Variants for LINC00957

RNA A-to-I editing events in lncRNA.

LncRNAediting ID	LncRNA Ensembl ID	Chromosome	Editing Position	Strand	Gene Type	Gene Name	Transcript ID	Transcript Type	Transcript Name
LncEditing_184200	ENSG00000235314.1	chr7	44042047	+	lincRNA	LINC00957	ENST00000441052.1	lincRNA	LINC00957-001
LncEditing_184209	ENSG00000235314.1	chr7	44042098	+	lincRNA	LINC00957	ENST00000441052.1	lincRNA	LINC00957-001
LncEditing_184228	ENSG00000235314.1	chr7	44042186	+	lincRNA	LINC00957	ENST00000441052.1	lincRNA	LINC00957-001
LncEditing_184230	ENSG00000235314.1	chr7	44042196	+	lincRNA	LINC00957	ENST00000441052.1	lincRNA	LINC00957-001

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID	LncRNA Index	Cancer Type	Chr_Postion_Strand	AVE1	AVE2	log2FC	W-value	P-value	Adjc.p-value	Change
ENSG00000235314	LncEditing_184200	KIRC	chr7_44042047_+	2.908016e+00	2.286593e+00	2.883209e+00	7.291043e+00	3.075646e-13	5.314430e-13	UP
ENSG00000235314	LncEditing_184228	KIRC	chr7_44042186_+	3.193265e+00	2.012295e+00	1.501072e+00	1.117391e+01	5.472020e-29	2.509698e-28	UP
ENSG00000235314	LncEditing_184230	KIRC	chr7_44042196_+	3.154263e+00	2.528099e+00	3.132340e+00	4.242425e+00	2.211178e-05	2.616091e-05	UP
ENSG00000235314	LncEditing_184228	DLBC	chr7_44042186_+	2.304214e+00	1.790324e+00	2.746842e+00	2.232008e+00	2.561444e-02	3.028374e-02	UP
ENSG00000235314	LncEditing_184200	GBM	chr7_44042047_+	3.247972e+00	1.553962e+00	9.402140e-01	7.825807e+00	5.044126e-15	8.871082e-14	UP
ENSG00000235314	LncEditing_184230	GBM	chr7_44042196_+	3.750395e+00	2.043440e+00	1.141497e+00	4.970932e+00	6.663197e-07	1.324454e-06	UP
ENSG00000235314	LncEditing_184200	MESO	chr7_44042047_+	2.745940e+00	1.353383e+00	9.796917e-01	5.192004e+00	2.080428e-07	2.396345e-06	UP
ENSG00000235314	LncEditing_184200	LGG	chr7_44042047_+	3.620918e+00	1.600250e+00	8.488546e-01	9.913441e+00	3.638942e-23	1.345075e-22	UP
ENSG00000235314	LncEditing_184200	ACC	chr7_44042047_+	4.509749e+00	3.320159e+00	2.263495e+00	2.613495e+00	8.962134e-03	1.052434e-02	UP
ENSG00000235314	LncEditing_184228	ACC	chr7_44042186_+	5.150010e+00	2.879608e+00	1.192317e+00	3.788072e+00	1.518208e-04	4.006818e-04	UP
ENSG00000235314	LncEditing_184200	KICH	chr7_44042047_+	7.902700e+00	1.182411e+01	-1.720242e+00	-2.886410e+00	3.896645e-03	6.412590e-03	DOWN
ENSG00000235314	LncEditing_184228	KICH	chr7_44042186_+	9.142529e+00	1.171178e+01	-2.798803e+00	-2.045004e+00	4.085447e-02	4.279992e-02	DOWN
ENSG00000235314	LncEditing_184200	SKCM	chr7_44042047_+	3.139331e+00	1.865971e+00	1.332392e+00	9.372797e+00	7.063536e-21	1.437554e-20	UP
ENSG00000235314	LncEditing_184228	SKCM	chr7_44042186_+	3.753923e+00	1.950569e+00	1.058757e+00	9.028884e+00	1.734316e-19	3.251843e-19	UP
ENSG00000235314	LncEditing_184200	PCPG	chr7_44042047_+	1.063691e+01	9.549911e+00	6.430053e+00	1.981917e+00	4.748857e-02	4.798222e-02	UP
ENSG00000235314	LncEditing_184228	PCPG	chr7_44042186_+	1.068452e+01	9.373484e+00	5.294807e+00	1.975306e+00	4.823341e-02	4.853299e-02	UP
ENSG00000235314	LncEditing_184200	KIRP	chr7_44042047_+	3.683819e+00	2.926996e+00	3.014033e+00	4.163864e+00	3.129064e-05	4.206437e-05	UP
ENSG00000235314	LncEditing_184228	KIRP	chr7_44042186_+	4.122428e+00	2.862879e+00	1.901042e+00	5.368781e+00	7.927045e-08	1.348198e-07	UP
ENSG00000235314	LncEditing_184200	THCA	chr7_44042047_+	1.547094e+00	1.229317e+00	3.014740e+00	6.040921e+00	1.532369e-09	2.794857e-09	UP
ENSG00000235314	LncEditing_184228	THCA	chr7_44042186_+	1.605598e+00	1.239847e+00	2.681333e+00	6.020953e+00	1.733926e-09	3.143705e-09	UP
ENSG00000235314	LncEditing_184200	CHOL	chr7_44042047_+	3.553929e+00	1.610339e+00	8.756179e-01	3.244071e+00	1.178342e-03	4.525339e-03	UP
ENSG00000235314	LncEditing_184228	CHOL	chr7_44042186_+	4.178170e+00	1.779054e+00	8.118459e-01	3.006027e+00	2.646857e-03	6.771654e-03	UP
ENSG00000235314	LncEditing_184200	THYM	chr7_44042047_+	2.688903e+00	1.535604e+00	1.237300e+00	4.270112e+00	1.953748e-05	3.921968e-05	UP
ENSG00000235314	LncEditing_184228	THYM	chr7_44042186_+	2.437019e+00	1.705006e+00	1.940464e+00	2.449961e+00	1.428718e-02	1.613261e-02	UP
ENSG00000235314	LncEditing_184200	OV	chr7_44042047_+	2.490618e+00	1.151115e+00	8.980917e-01	1.117941e+01	5.142809e-29	5.629539e-28	UP
ENSG00000235314	LncEditing_184209	OV	chr7_44042098_+	2.622390e+00	1.277941e+00	9.642631e-01	8.347317e+00	6.983093e-17	2.297300e-16	UP
ENSG00000235314	LncEditing_184228	OV	chr7_44042186_+	2.015771e+00	9.838000e-01	9.662814e-01	1.152969e+01	9.347663e-31	1.312241e-29	UP
ENSG00000235314	LncEditing_184230	OV	chr7_44042196_+	2.235752e+00	1.293775e+00	1.267149e+00	7.698979e+00	1.371572e-14	3.682221e-14	UP
ENSG00000235314	LncEditing_184200	LUAD	chr7_44042047_+	2.120804e+00	1.279185e+00	1.371015e+00	8.906873e+00	5.249202e-19	1.403027e-18	UP
ENSG00000235314	LncEditing_184228	STAD	chr7_44042186_+	1.655479e+00	7.743913e-01	9.123140e-01	9.419454e+00	4.534408e-21	2.352635e-20	UP
ENSG00000235314	LncEditing_184200	CESC	chr7_44042047_+	1.725662e+00	9.729338e-01	1.209575e+00	6.708163e+00	1.970894e-11	5.023352e-11	UP
ENSG00000235314	LncEditing_184200	PRAD	chr7_44042047_+	2.063025e+00	1.333018e+00	1.587138e+00	7.826124e+00	5.031409e-15	1.339443e-14	UP
ENSG00000235314	LncEditing_184228	PRAD	chr7_44042186_+	2.112271e+00	1.382812e+00	1.636152e+00	5.781864e+00	7.387758e-09	1.219599e-08	UP
ENSG00000235314	LncEditing_184200	BRCA	chr7_44042047_+	3.159166e+00	1.453995e+00	8.932390e-01	1.827794e+01	1.240303e-74	1.701321e-73	UP
ENSG00000235314	LncEditing_184230	BRCA	chr7_44042196_+	3.548410e+00	1.914271e+00	1.123119e+00	1.101059e+01	3.397639e-28	5.937701e-28	UP

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID	LncRNA Index	Correlation	P-value	Adjc.p-value
ENSG00000235314	LncEditing_184230	-3.093758e-01	6.915669e-03	9.006099e-03
ENSG00000235314	LncEditing_184228	-3.704205e-01	4.130744e-04	6.317609e-04
ENSG00000235314	LncEditing_184200	-6.849044e-01	9.792177e-03	3.416904e-02
ENSG00000235314	LncEditing_184200	-3.774373e-01	6.811476e-07	7.293357e-06
ENSG00000235314	LncEditing_184200	-4.038649e-01	6.554016e-03	1.035957e-02
ENSG00000235314	LncEditing_184228	-3.710595e-01	7.028849e-04	1.579746e-03
ENSG00000235314	LncEditing_184200	-6.444715e-01	2.937604e-05	6.071049e-04
ENSG00000235314	LncEditing_184228	-5.706862e-01	6.898860e-03	1.296149e-02
ENSG00000235314	LncEditing_184200	-4.716891e-01	1.143701e-05	2.990339e-05
ENSG00000235314	LncEditing_184228	-4.539676e-01	6.998965e-05	1.298020e-04
ENSG00000235314	LncEditing_184228	-3.715718e-01	8.570977e-03	9.078887e-03
ENSG00000235314	LncEditing_184200	-3.188411e-01	1.090262e-03	2.473033e-03
ENSG00000235314	LncEditing_184228	-4.354857e-01	8.434831e-05	3.975168e-04

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID

LncRNA ENST ID

PC Gene Name

PC Gene ID

PC ENST ID

nDG

Cancer with PC gene up-regulation

Cancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000235314.1	ENST00000416824.1	189	895	1464
ENSG00000235314.1	ENST00000441052.1	268	1016	210

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential