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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000234678

Summary for ELF3-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000234678

Gene symbol

ELF3-AS1

Gene nameELF3 antisense RNA 1
HGNC

40211

Entrez ID
Gene typeantisense
Synonyms01q32.1|ELF3-AS1|RP11-465N4.4
UniProtAcc

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Structure and expression level for ELF3-AS1

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002346788.306178e+011.182233e+003.166648e-013.733389e+001.889210e-047.771760e-04UPCHOL
ENSG000002346781.121910e+021.440354e+002.957106e-014.870824e+001.110000e-069.780000e-06UPBLCA
ENSG000002346781.343721e+022.003566e+006.152940e-013.256274e+001.128846e-038.721681e-03UPCESC
ENSG000002346786.686111e+012.404193e+001.652432e-011.454942e+015.890000e-485.640000e-46UPUCEC
ENSG000002346787.705358e+011.176680e+001.157164e-011.016866e+012.740000e-241.220000e-22UPPRAD
ENSG000002346781.166858e+021.328375e+001.344660e-019.878893e+005.140000e-233.910000e-22UPLUSC
ENSG000002346789.146102e+011.352587e+008.673933e-021.559370e+018.030000e-551.990000e-53UPBRCA
ENSG000002346781.139916e+021.726562e+001.219924e-011.415303e+011.790000e-458.070000e-44UPLUAD
ENSG000002346781.017599e+021.710030e+001.895918e-019.019533e+001.890000e-193.430000e-18UPLIHC

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002346786.364019e-012.616578e-06CHOL3.284392e-05
ENSG000002346783.736457e-011.064327e-14LIHC1.135964e-13
ENSG000002346783.667558e-015.509392e-19PRAD1.060828e-17
ENSG000002346783.738129e-016.619937e-21UCEC4.573774e-19

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lncRNA-Protein interaction for ELF3-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000234678ENST00000415582RP11-465N4.4ENSG00000134815DHX3433.591.1494Q14147RBPNA

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lncRNA-DNA interaction for ELF3-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for ELF3-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
FRMD6,CELF2,QKI,ABCA8,MAP3K3,IL6ST,TNS1,C1R,MSRB3,FERMT2,ACTN1,KANK2,GAS7,GNAI2,ZCCHC24,KIRREL1,A2M,MPDZ,JAM2,TUBB6,SLC12A4
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000234678ENST00000415582exon_skip_44853chr10:104010815-104010908-9.45-0.1500SLKENST00000369755In-frame
ENSG00000234678ENST00000415582exon_skip_44998chr10:110132304-110132400-8.62-0.1002ADD3ENST00000356080In-frame
ENSG00000234678ENST00000415582exon_skip_48713chr10:34336198-34336243-8.67-0.2709PARD3ENST00000374789In-frame
ENSG00000234678ENST00000415582exon_skip_64939chr11:112230207-112230230-5.20-0.3714PTSENST00000280362Frame-shift
ENSG00000234678ENST00000415582exon_skip_98384chr12:124327408-124327633-22.66-0.1074NCOR2ENST00000405201In-frame
ENSG00000234678ENST00000415582exon_skip_114200chr14:73279280-73279424-13.97-0.1027NUMBENST00000355058,ENST00000555238In-frame
ENSG00000234678ENST00000415582exon_skip_378912chr3:152446703-152446757-6.54-0.1924MBNL1ENST00000282486,ENST00000463374In-frame
ENSG00000234678ENST00000415582exon_skip_386291chr3:108050577-108050602-7.67-0.6973CD47ENST00000361309Frame-shift
ENSG00000234678ENST00000415582exon_skip_423795chr4:55888887-55888932-7.01-0.2261EXOC1ENST00000346134,ENST00000381295In-frame
ENSG00000234678ENST00000419190exon_skip_435063chr5:66075023-66075230-19.01-0.1284ERBINENST00000284037In-frame
ENSG00000234678ENST00000415582exon_skip_456460chr6:17771113-17771218-11.99-0.1164KIF13AENST00000259711In-frame
ENSG00000234678ENST00000415582exon_skip_461111chr6:90544551-90544632-13.60-0.1789MAP3K7ENST00000369329In-frame
ENSG00000234678ENST00000415582exon_skip_499771chr9:128592982-128593042-9.25-0.1927SPTAN1ENST00000372731In-frame
ENSG00000234678ENST00000415582exon_skip_150188chr17:27643524-27643620-11.77-0.1706LGALS9ENST00000395473In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000234678ENST00000415582exon_skip_21610chr1:9737497-9737554-7.47-0.2075CLSTN1ENST00000377298In-frame
ENSG00000234678ENST00000415582exon_skip_33516chr1:156938417-156938513-12.71-0.1412ARHGEF11ENST00000361409In-frame
ENSG00000234678ENST00000415582exon_skip_43507chr10:84499874-84499959-10.76-0.2196CCSER2ENST00000224756Frame-shift
ENSG00000234678ENST00000415582exon_skip_52231chr10:93392916-93392955-6.00-0.2069MYOFENST00000359263In-frame
ENSG00000234678ENST00000415582exon_skip_287874chr17:29085603-29085648-4.32-0.1271MYO18AENST00000527372In-frame
ENSG00000234678ENST00000415582exon_skip_326917chr2:74532618-74532714-10.63-0.1155HTRA2ENST00000258080In-frame
ENSG00000234678ENST00000415582exon_skip_361434chr21:25997359-25997416-12.79-0.2907APPENST00000346798In-frame
ENSG00000234678ENST00000415582exon_skip_376144chr3:100311832-100311877-5.23-0.1162TBC1D23ENST00000394144In-frame
ENSG00000234678ENST00000415582exon_skip_382356chr3:37091466-37091538-7.13-1.0186LRRFIP2ENST00000336686In-frame
ENSG00000234678ENST00000415582exon_skip_436488chr5:96726793-96726859-9.47-0.1435CASTENST00000341926,ENST00000395813In-frame
ENSG00000234678ENST00000415582exon_skip_451515chr6:41080810-41080897-12.63-0.2070NFYAENST00000341376In-frame
ENSG00000234678ENST00000415582exon_skip_337919chr2:27445744-27445843-9.87-0.1352IFT172ENST00000260570In-frame

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for ELF3-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation
ENSG00000234678ENST00000419190ACTN1ENSG00000072110ENST00000438964-0.27441-BLCA,UCEC
ENSG00000234678ENST00000419190ACTN1ENSG00000072110ENST00000376839-0.27839-BLCA,UCEC
ENSG00000234678ENST00000419190ACTN1ENSG00000072110ENST00000555075-0.235312-BLCA,UCEC
ENSG00000234678ENST00000419190FRMD6ENSG00000139926ENST00000555197-0.1766134-UCEC,PRAD,LIHC
ENSG00000234678ENST00000419190TUBB6ENSG00000176014ENST00000590388-0.15621-BLCA,UCEC,BRCA,LUAD
ENSG00000234678ENST00000419190TUBB6ENSG00000176014ENST00000592683-0.1684429-BLCA,UCEC,BRCA,LUAD
ENSG00000234678ENST00000419190TUBB6ENSG00000176014ENST00000590967-0.26376-BLCA,UCEC,BRCA,LUAD
ENSG00000234678ENST00000419190TUBB6ENSG00000176014ENST00000586691-0.1025256-BLCA,UCEC,BRCA,LUAD
ENSG00000234678ENST00000419190ZCCHC24ENSG00000165424ENST00000372333-0.16141-CHOL,BLCA,CESC,UCEC,LUSC,BRCA,LUAD,LIHC
ENSG00000234678ENST00000419190MSRB3ENSG00000174099ENST00000541897-0.120468-BLCA,CESC,UCEC,PRAD,LUSC,BRCA,LUAD
ENSG00000234678ENST00000419190MSRB3ENSG00000174099ENST00000535664-0.1098200-BLCA,CESC,UCEC,PRAD,LUSC,BRCA,LUAD
ENSG00000234678ENST00000419190MSRB3ENSG00000174099ENST00000446731-0.1456520-BLCA,CESC,UCEC,PRAD,LUSC,BRCA,LUAD
ENSG00000234678ENST00000419190KANK2ENSG00000197256ENST00000589894-0.123818-BLCA,CESC,UCEC,PRAD,LUSC,BRCA,LUAD
ENSG00000234678ENST00000419190C1RENSG00000159403ENST00000536053-0.1348117-CHOL,BLCA,UCEC,LIHC
ENSG00000234678ENST00000419190C1RENSG00000159403ENST00000535233-0.1348117-CHOL,BLCA,UCEC,LIHC
ENSG00000234678ENST00000419190FERMT2ENSG00000073712ENST00000399304-0.1551453-CHOL,BLCA,CESC,UCEC,PRAD,LUSC,BRCA,LUAD,LIHC
ENSG00000234678ENST00000419190FERMT2ENSG00000073712ENST00000557562-0.16331-CHOL,BLCA,CESC,UCEC,PRAD,LUSC,BRCA,LUAD,LIHC
ENSG00000234678ENST00000419190MPDZENSG00000107186ENST00000536827-0.141055-CHOL,BLCA,UCEC,LUSC,BRCA,LIHC
ENSG00000234678ENST00000419190MPDZENSG00000107186ENST00000447879-0.1476473-CHOL,BLCA,UCEC,LUSC,BRCA,LIHC
ENSG00000234678ENST00000419190MPDZENSG00000107186ENST00000546205-0.4336672-CHOL,BLCA,UCEC,LUSC,BRCA,LIHC
ENSG00000234678ENST00000419190ABCA8ENSG00000141338ENST00000586539-0.381565-CHOL,BRCA,LUAD,LIHC
ENSG00000234678ENST00000419190A2MENSG00000175899ENST00000318602-0.1584358-CHOL,BLCA,CESC,UCEC,LUSC,BRCA,LUAD,LIHC
ENSG00000234678ENST00000419190GNAI2ENSG00000114353ENST00000422163-0.10701-CESC,LUSC
ENSG00000234678ENST00000419190GNAI2ENSG00000114353ENST00000266027-0.10701-CESC,LUSC
ENSG00000234678ENST00000419190GNAI2ENSG00000114353ENST00000313601-0.10701-CESC,LUSC
ENSG00000234678ENST00000419190SLC12A4ENSG00000124067ENST00000572037-0.14751-UCEC,LUSC,LUAD
ENSG00000234678ENST00000419190SLC12A4ENSG00000124067ENST00000541864-0.14751-UCEC,LUSC,LUAD
ENSG00000234678ENST00000419190SLC12A4ENSG00000124067ENST00000576616-0.10221-UCEC,LUSC,LUAD
ENSG00000234678ENST00000419190SLC12A4ENSG00000124067ENST00000537830-0.138767-UCEC,LUSC,LUAD
ENSG00000234678ENST00000419190SLC12A4ENSG00000124067ENST00000570616-0.116811-UCEC,LUSC,LUAD
ENSG00000234678ENST00000419190GAS7ENSG00000007237ENST00000583882-0.160644-BLCA,CESC,UCEC,LUSC,BRCA,LUAD
ENSG00000234678ENST00000419190GAS7ENSG00000007237ENST00000542249-0.11971-BLCA,CESC,UCEC,LUSC,BRCA,LUAD
ENSG00000234678ENST00000419190GAS7ENSG00000007237ENST00000396115-0.24421-BLCA,CESC,UCEC,LUSC,BRCA,LUAD
ENSG00000234678ENST00000419190GAS7ENSG00000007237ENST00000579158-0.24421-BLCA,CESC,UCEC,LUSC,BRCA,LUAD
ENSG00000234678ENST00000419190TNS1ENSG00000079308ENST00000453356-0.1334381-BLCA,CESC,UCEC,PRAD,LUSC,BRCA,LUAD
ENSG00000234678ENST00000419190MAP3K3ENSG00000198909ENST00000584573-0.186957-CESC,UCEC,LUSC,LUAD
ENSG00000234678ENST00000415582ACTN1ENSG00000072110ENST00000193403-0.1060316-BLCA,UCEC
ENSG00000234678ENST00000415582ACTN1ENSG00000072110ENST00000394419-0.1060316-BLCA,UCEC
ENSG00000234678ENST00000415582ACTN1ENSG00000072110ENST00000438964-0.1060316-BLCA,UCEC
ENSG00000234678ENST00000415582ACTN1ENSG00000072110ENST00000376839-0.17931-BLCA,UCEC
ENSG00000234678ENST00000415582ACTN1ENSG00000072110ENST00000555075-0.17931-BLCA,UCEC
ENSG00000234678ENST00000415582FRMD6ENSG00000139926ENST00000557405-0.30591-UCEC,PRAD,LIHC
ENSG00000234678ENST00000415582FRMD6ENSG00000139926ENST00000555197-0.1588203-UCEC,PRAD,LIHC
ENSG00000234678ENST00000415582TUBB6ENSG00000176014ENST00000590388-0.1399275-BLCA,UCEC,BRCA,LUAD
ENSG00000234678ENST00000415582TUBB6ENSG00000176014ENST00000586653-0.1048204-BLCA,UCEC,BRCA,LUAD
ENSG00000234678ENST00000415582TUBB6ENSG00000176014ENST00000592683-0.1405347-BLCA,UCEC,BRCA,LUAD
ENSG00000234678ENST00000415582TUBB6ENSG00000176014ENST00000590967-0.1591286-BLCA,UCEC,BRCA,LUAD
ENSG00000234678ENST00000415582JAM2ENSG00000154721ENST00000400532-0.12321-BLCA,UCEC,LUSC,BRCA,LUAD
ENSG00000234678ENST00000415582ZCCHC24ENSG00000165424ENST00000372333-0.1712379-CHOL,BLCA,CESC,UCEC,LUSC,BRCA,LUAD,LIHC
ENSG00000234678ENST00000415582MSRB3ENSG00000174099ENST00000535664-0.6540223-BLCA,CESC,UCEC,PRAD,LUSC,BRCA,LUAD
ENSG00000234678ENST00000415582KANK2ENSG00000197256ENST00000589894-0.1810381-BLCA,CESC,UCEC,PRAD,LUSC,BRCA,LUAD
ENSG00000234678ENST00000415582MPDZENSG00000107186ENST00000536827-0.133815-CHOL,BLCA,UCEC,LUSC,BRCA,LIHC
ENSG00000234678ENST00000415582MPDZENSG00000107186ENST00000447879-0.2000298-CHOL,BLCA,UCEC,LUSC,BRCA,LIHC
ENSG00000234678ENST00000415582MPDZENSG00000107186ENST00000546205-0.4336391-CHOL,BLCA,UCEC,LUSC,BRCA,LIHC
ENSG00000234678ENST00000415582ABCA8ENSG00000141338ENST00000586539-0.2665432-CHOL,BRCA,LUAD,LIHC
ENSG00000234678ENST00000415582A2MENSG00000175899ENST00000318602-0.1038218-CHOL,BLCA,CESC,UCEC,LUSC,BRCA,LUAD,LIHC
ENSG00000234678ENST00000415582GAS7ENSG00000007237ENST00000542249-0.11051-BLCA,CESC,UCEC,LUSC,BRCA,LUAD
ENSG00000234678ENST00000415582GAS7ENSG00000007237ENST00000579158-0.1416329-BLCA,CESC,UCEC,LUSC,BRCA,LUAD
ENSG00000234678ENST00000415582TNS1ENSG00000079308ENST00000453356-0.1310305-BLCA,CESC,UCEC,PRAD,LUSC,BRCA,LUAD
ENSG00000234678ENST00000415582MAP3K3ENSG00000198909ENST00000584573-0.1165264-CESC,UCEC,LUSC,LUAD
ENSG00000234678ENST00000419190MAP3K3ENSG00000198909ENST00000577395-0.2123271-CESC,UCEC,LUSC,LUAD
ENSG00000234678ENST00000419190IL6STENSG00000134352ENST00000502326-0.2983573-CHOL,BLCA,CESC,UCEC,LUSC,LIHC
ENSG00000234678ENST00000415582MAP3K3ENSG00000198909ENST00000577395-0.1418350-CESC,UCEC,LUSC,LUAD
ENSG00000234678ENST00000415582IL6STENSG00000134352ENST00000502326-0.2983292-CHOL,BLCA,CESC,UCEC,LUSC,LIHC

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000234678.1ENST00000419190.174401177
ENSG00000234678.1ENST00000415582.198277573