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lncRNA: ENSG00000234614

Summary for C2CD4D-AS1

Gene summary

Gene information	Ensembl ID	ENSG00000234614
	Gene symbol	C2CD4D-AS1
	Gene name	C2CD4D and THEM5 antisense RNA 1
	HGNC	54045
	Entrez ID
	Gene type	antisense
	Synonyms	01q21.3\|AL450992.2\|C2CD4D-AS1
	UniProtAcc

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Structure and expression level for C2CD4D-AS1

AS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000234614	3.953171e+01	-2.859977e+00	5.986706e-01	-4.777213e+00	1.780000e-06	1.380000e-05	DOWN	GBM
ENSG00000234614	8.820844e+01	1.065722e+00	1.913793e-01	5.568636e+00	2.570000e-08	1.190000e-07	UP	THCA
ENSG00000234614	2.713238e+02	4.693740e+00	7.346129e-01	6.389406e+00	1.670000e-10	1.110000e-08	UP	CESC
ENSG00000234614	2.262439e+02	1.932862e+00	1.559484e-01	1.239424e+01	2.810000e-35	7.450000e-34	UP	LUAD
ENSG00000234614	9.717628e+01	1.497905e+00	1.643763e-01	9.112656e+00	8.040000e-20	1.510000e-18	UP	LIHC
ENSG00000234614	1.223057e+02	1.162992e+00	2.710969e-01	4.289948e+00	1.790000e-05	9.000000e-05	UP	STAD

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000234614	4.016471e-01	6.243376e-03	CHOL	7.778204e-03

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lncRNA-Protein interaction for C2CD4D-AS1

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000123636	BAZ2B	52.9	94.6899	Q9UIF8	TF,Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000080503	SMARCA2	48.54	93.175	P51531	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000155827	RNF20	46.92	90.6813	Q5VTR2	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000054267	ARID4B	44.34	93.7071	Q4LE39	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000009954	BAZ1B	43.55	93.6438	Q9UIG0	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000005483	KMT2E	40.54	93.5481	Q8IZD2	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000181555	SETD2	40.53	93.6504	Q9BYW2	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000165671	NSD1	39.9	94.8303	Q96L73	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000100393	EP300	36.66	94.6753	Q09472	Epi	ChIP-seq
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000005339	CREBBP	36.62	94.9387	Q92793	Epi	ChIP-seq
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000055609	KMT2C	35.35	94.7677	Q8NEZ4	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000084676	NCOA1	32.84	93.3636	Q15788	TF,Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000078403	MLLT10	32.47	92.1617	P55197	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000076108	BAZ2A	32.23	93.0396	Q9UIF9	TF,RBP,Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000143970	ASXL2	30.99	92.2108	Q76L83	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000055483	USP36	28.68	92.8265	Q9P275	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000084093	REST	28.39	91.9802	Q13127	TF,Epi	ChIP-seq
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000183495	EP400	25.48	94.6803	Q96L91	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000083168	KAT6A	23.6	92.7358	Q92794	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000117713	ARID1A	19.04	93.5037	O14497	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000120071	KANSL1	18.06	90.4689	Q7Z3B3	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000067369	TP53BP1	50.93	93.1485	Q12888	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000077097	TOP2B	48.63	91.9946	Q02880	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000128908	INO80	48.01	90.2179	Q9ULG1	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000146247	PHIP	44.66	93.2642	Q8WWQ0	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000118058	KMT2A	41.94	96.1353	Q03164	TF,Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000085224	ATRX	37.78	95.5576	P46100	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000101126	ADNP	36.39	91.519	Q9H2P0	TF,Epi	ChIP-seq
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000116731	PRDM2	35.09	93.0167	Q13029	TF,Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000183337	BCOR	32.92	92.4185	Q6W2J9	Epi	ChIP-seq
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000187605	TET3	32.86	92.6006	O43151	TF,Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000147133	TAF1	32.78	92.0457	P21675	Epi	ChIP-seq
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000139613	SMARCC2	30.28	92.4591	Q8TAQ2	Epi	ChIP-seq
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000171634	BPTF	29.86	95.8932	Q12830	TF,Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000140396	NCOA2	28.22	93.9507	Q15596	TF,Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000134852	CLOCK	27.91	90.3516	O15516	TF,Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000167548	KMT2D	26.64	95.9479	O14686	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000163635	ATXN7	23.18	90.3054	O15265	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000049618	ARID1B	17.99	93.2516	Q8NFD5	Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000156650	KAT6B	15.22	94.1849	Q8WYB5	Epi	NA

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000123636	BAZ2B	52.9	94.8434	Q9UIF8	TF,Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000102189	EEA1	52.1	94.6742	Q15075	TF	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000144747	TMF1	45.32	90.8973	P82094	TF	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000118058	KMT2A	41.94	96.1862	Q03164	TF,Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000100207	TCF20	38.31	95.0774	Q9UGU0	TF	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000124782	RREB1	36.74	92.3632	Q92766	TF	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000101126	ADNP	36.39	91.3498	Q9H2P0	TF,Epi	ChIP-seq
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000116731	PRDM2	35.09	93.0671	Q13029	TF,Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000187605	TET3	32.86	92.5843	O43151	TF,Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000084676	NCOA1	32.84	93.6183	Q15788	TF,Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000076108	BAZ2A	32.23	92.8533	Q9UIF9	TF,RBP,Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000147124	ZNF41	31.67	92.2428	P51814	TF	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000171634	BPTF	29.86	96.0962	Q12830	TF,Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000005889	ZFX	29.29	91.2441	P17010	TF	ChIP-seq
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000084093	REST	28.39	91.7669	Q13127	TF,Epi	ChIP-seq
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000140396	NCOA2	28.22	94.0529	Q15596	TF,Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000159140	SON	28.13	93.431	P18583	TF,RBP	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000134852	CLOCK	27.91	90.63	O15516	TF,Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000170448	NFXL1	22.34	91.1167	Q6ZNB6	TF	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000124459	ZNF45	20.44	92.1061	Q02386	TF	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000188786	MTF1	20.21	90.4942	Q14872	TF	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000213079	SCAF8	37.94	94.6992	Q9UPN6	RBP	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000198000	NOL8	36.3	93.6763	Q76FK4	RBP	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000137776	SLTM	33.79	93.2712	Q9NWH9	RBP	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000076108	BAZ2A	32.23	92.9858	Q9UIF9	TF,RBP,Epi	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000159140	SON	28.13	93.5944	P18583	TF,RBP	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000133226	SRRM1	13.94	94.1888	Q8IYB3	RBP	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000184863	RBM33	9.71	91.8007	Q96EV2	RBP	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000138757	G3BP2	6.71	90.7066	Q9UN86	RBP	NA
ENSG00000234614	ENST00000434182	AL450992.2	ENSG00000111605	CPSF6	5.42	90.0732	Q16630	RBP	NA

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lncRNA-DNA interaction for C2CD4D-AS1

lncRNA targets the enhancer region and positively regulates the gene expression.

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for C2CD4D-AS1

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

Only predicted by lncTar

ITPA,MRPL52,PQBP1,EIF6,SF3A2,MYG1,SNRPA,MYL6,TMEM256,NDUFA11,NDUFA13,UXT,PFDN5,SGF29,RFXANK,RPL23A,TRAPPC2L,MRPS15,PSMB6,VKORC1,METTL26,RUVBL2,HCFC1R1,EMC8,BID,CIAO2B,EIF3F,MVB12A,STX8,NUBP2,NSMCE1,TRPT1,PGLS

Exist in public source

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

LncRNA Ensembl ID

LncRNA ENST ID

Exon ID

Skipped Exon

ndG

Gene name with skipped exon

TransID with skipped exon

ORF mutation

-lncRNA and exonskipping events are negatively correlated.

LncRNA Ensembl ID

LncRNA ENST ID

Exon ID

Skipped Exon

ndG

Gene name with skipped exon

TransID with skipped exon

LOF

lncRNA targets by miRNA.

LncRNA Ensembl ID

miRNA ID

LncRNA ENST ID

Binding site in lncRNA

Score

Energy

Align Len

Public source

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Variants for C2CD4D-AS1

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID	LncRNA ENST ID	PC Gene Name	PC Gene ID	PC ENST ID	dG	nDG	Cancer with PC gene up-regulation	Cancer with PC gene Down-regulation
ENSG00000234614	ENST00000434182	RFXANK	ENSG00000064490	ENST00000303088	-0.1434	333	GBM	-
ENSG00000234614	ENST00000434182	RFXANK	ENSG00000064490	ENST00000456252	-0.1487	336	GBM	-
ENSG00000234614	ENST00000434182	RFXANK	ENSG00000064490	ENST00000407360	-0.2382	400	GBM	-
ENSG00000234614	ENST00000434182	RFXANK	ENSG00000064490	ENST00000392324	-0.1487	336	GBM	-
ENSG00000234614	ENST00000434182	RFXANK	ENSG00000064490	ENST00000544923	-0.1487	339	GBM	-
ENSG00000234614	ENST00000434182	PGLS	ENSG00000130313	ENST00000252603	-0.1400	266	GBM	-
ENSG00000234614	ENST00000434182	PGLS	ENSG00000130313	ENST00000595782	-0.1400	266	GBM	-
ENSG00000234614	ENST00000434182	MVB12A	ENSG00000141971	ENST00000529939	-0.1240	212	GBM	-
ENSG00000234614	ENST00000434182	MVB12A	ENSG00000141971	ENST00000528515	-0.2159	293	GBM	-
ENSG00000234614	ENST00000434182	VKORC1	ENSG00000167397	ENST00000394971	-0.1286	124	GBM	LIHC
ENSG00000234614	ENST00000434182	VKORC1	ENSG00000167397	ENST00000498155	-0.3278	78	GBM	LIHC
ENSG00000234614	ENST00000434182	RPL23A	ENSG00000198242	ENST00000496182	-0.1178	90	GBM	-
ENSG00000234614	ENST00000434182	RPL23A	ENSG00000198242	ENST00000394938	-0.1178	90	GBM	-
ENSG00000234614	ENST00000434182	RPL23A	ENSG00000198242	ENST00000394935	-0.1264	35	GBM	-
ENSG00000234614	ENST00000434182	RPL23A	ENSG00000198242	ENST00000355731	-0.2272	349	GBM	-
ENSG00000234614	ENST00000434182	RPL23A	ENSG00000198242	ENST00000472628	-0.1178	90	GBM	-
ENSG00000234614	ENST00000434182	RPL23A	ENSG00000198242	ENST00000578181	-0.1310	234	GBM	-

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000234614.1	ENST00000434182.1	33	71	172

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential