lncRNA targets the enhancer region and positively regulates the gene expression. |
lncRNA targets the promoter region and positively regulates the gene expression. |
lncRNA targets the promoter region and negatively regulates the gene expression. |
lncRNA targets the 3'UTR region and negatively regulates the mRNA. |
Only predicted by lncTar | BPTF,NCOA2,CHERP,TMF1,LARP4,GLYR1,DDX46,CPSF7,AKAP1,NR2C2,ZNF91,SF3A1,DDX6,AQR,RREB1 | Exist in public source | NA |
lncRNA targets the skipped exon region. | -lncRNA and exonskipping events are positively correlated. |
LncRNA Ensembl ID | LncRNA ENST ID | Exon ID | Skipped Exon | dG | ndG | Gene name with skipped exon | TransID with skipped exon | ORF mutation | ENSG00000233901 | ENST00000423122 | exon_skip_96112 | chr12:109945259-109945349 | -16.17 | -0.2651 | GIT2 | ENST00000355312 | In-frame | ENSG00000233901 | ENST00000423122 | exon_skip_75223 | chr11:72012400-72012442 | -5.72 | -0.1682 | NUMA1 | ENST00000393695 | In-frame | ENSG00000233901 | ENST00000423122 | exon_skip_382356 | chr3:37091466-37091538 | -6.97 | -0.2178 | LRRFIP2 | ENST00000336686 | In-frame |
-lncRNA and exonskipping events are negatively correlated. |
LncRNA Ensembl ID | LncRNA ENST ID | Exon ID | Skipped Exon | dG | ndG | Gene name with skipped exon | TransID with skipped exon | LOF | ENSG00000233901 | ENST00000423122 | exon_skip_85538 | chr12:71894324-71894375 | -9.52 | -0.2322 | TBC1D15 | ENST00000550746 | In-frame | ENSG00000233901 | ENST00000423122 | exon_skip_120396 | chr14:105150990-105151104 | -13.73 | -0.1271 | JAG2 | ENST00000331782 | In-frame | ENSG00000233901 | ENST00000423122 | exon_skip_153096 | chr17:44074968-44075087 | -11.65 | -0.1975 | G6PC3 | ENST00000269097 | Frame-shift | ENSG00000233901 | ENST00000423122 | exon_skip_305632 | chr19:35262545-35262692 | -15.91 | -0.1283 | LSR | ENST00000361790 | In-frame | ENSG00000233901 | ENST00000423122 | exon_skip_455363 | chr6:161098277-161098427 | -22.50 | -0.2163 | MAP3K4 | ENST00000392142 | In-frame |
lncRNA targets by miRNA. |
LncRNA Ensembl ID | miRNA ID | LncRNA ENST ID | Binding site in lncRNA | Score | Energy | Align Len | Public source |
RNA A-to-I editing events in lncRNA. |
LncRNAediting ID | LncRNA Ensembl ID | Chromosome | Editing Position | Strand | Gene Type | Gene Name | Transcript ID | Transcript Type | Transcript Name | LncEditing_221235 | ENSG00000233901.4 | chr9 | 129344510 | + | lincRNA | LINC01503 | ENST00000444125.1 | lincRNA | LINC01503-003 | LncEditing_221241 | ENSG00000233901.4 | chr9 | 129344522 | + | lincRNA | LINC01503 | ENST00000444125.1 | lincRNA | LINC01503-003 | LncEditing_221259 | ENSG00000233901.4 | chr9 | 129344549 | + | lincRNA | LINC01503 | ENST00000444125.1 | lincRNA | LINC01503-003 | LncEditing_221262 | ENSG00000233901.4 | chr9 | 129344550 | + | lincRNA | LINC01503 | ENST00000444125.1 | lincRNA | LINC01503-003 | LncEditing_221457 | ENSG00000233901.4 | chr9 | 129347250 | + | lincRNA | LINC01503 | ENST00000444125.1 | lincRNA | LINC01503-003 | LncEditing_221466 | ENSG00000233901.4 | chr9 | 129347276 | + | lincRNA | LINC01503 | ENST00000444125.1 | lincRNA | LINC01503-003 | LncEditing_221469 | ENSG00000233901.4 | chr9 | 129347284 | + | lincRNA | LINC01503 | ENST00000444125.1 | lincRNA | LINC01503-003 |
Edited-associated DElncRNAs in cancer. |
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LncRNA Ensembl ID | LncRNA Index | Cancer Type | Chr_Postion_Strand | AVE1 | AVE2 | log2FC | W-value | P-value | Adjc.p-value | Change | ENSG00000233901 | LncEditing_221457 | DLBC | chr9_129347250_+ | 3.003800e+00 | 1.435510e+00 | 9.387687e-01 | 2.611165e+00 | 9.023439e-03 | 1.384000e-02 | UP | ENSG00000233901 | LncEditing_221469 | GBM | chr9_129347284_+ | 7.352844e+00 | 4.852035e+00 | 1.667466e+00 | 4.148151e+00 | 3.351718e-05 | 5.030686e-05 | UP | ENSG00000233901 | LncEditing_221457 | LGG | chr9_129347250_+ | 2.741332e+00 | 1.830210e+00 | 1.715654e+00 | 7.069959e+00 | 1.549799e-12 | 2.655724e-12 | UP | ENSG00000233901 | LncEditing_221457 | PCPG | chr9_129347250_+ | 2.655698e+00 | 1.906553e+00 | 2.091506e+00 | 4.041070e+00 | 5.320789e-05 | 8.314801e-05 | UP | ENSG00000233901 | LncEditing_221235 | OV | chr9_129344510_+ | 3.046071e+01 | 1.439677e+01 | 9.248943e-01 | 5.821916e+00 | 5.817677e-09 | 8.937935e-09 | UP | ENSG00000233901 | LncEditing_221241 | OV | chr9_129344522_+ | 3.111867e+01 | 1.412328e+01 | 8.774201e-01 | 5.921116e+00 | 3.197648e-09 | 5.026046e-09 | UP | ENSG00000233901 | LncEditing_221262 | OV | chr9_129344550_+ | 2.995067e+01 | 1.300872e+01 | 8.311797e-01 | 7.282109e+00 | 3.286423e-13 | 7.573599e-13 | UP | ENSG00000233901 | LncEditing_221466 | OV | chr9_129347276_+ | 9.129971e+00 | 1.713390e+01 | -1.101113e+00 | -3.544705e+00 | 3.930533e-04 | 4.370164e-04 | DOWN | ENSG00000233901 | LncEditing_221469 | OV | chr9_129347284_+ | 1.074566e+01 | 1.770562e+01 | -1.388016e+00 | -2.880639e+00 | 3.968701e-03 | 4.187287e-03 | DOWN | ENSG00000233901 | LncEditing_221259 | ESCA | chr9_129344549_+ | 8.549247e+00 | 3.633569e+00 | 8.101034e-01 | 5.091952e+00 | 3.543963e-07 | 6.098643e-07 | UP | ENSG00000233901 | LncEditing_221262 | ESCA | chr9_129344550_+ | 7.413812e+00 | 3.465537e+00 | 9.114636e-01 | 5.532170e+00 | 3.162925e-08 | 6.356175e-08 | UP | ENSG00000233901 | LncEditing_221469 | ESCA | chr9_129347284_+ | 5.507748e+00 | 4.340629e+00 | 2.910715e+00 | 2.659076e+00 | 7.835527e-03 | 8.340917e-03 | UP |
Correlation between RNA A-to-I editing events's frequecy and lncRNA expression. |
LncRNA Ensembl ID | LncRNA Index | Correlation | P-value | Adjc.p-value | ENSG00000233901 | LncEditing_221466 | -3.665726e-01 | 6.939437e-03 | 9.006099e-03 | ENSG00000233901 | LncEditing_221469 | -4.143706e-01 | 4.019701e-05 | 2.205504e-04 | ENSG00000233901 | LncEditing_221469 | -4.680302e-01 | 2.108455e-02 | 3.043454e-02 | ENSG00000233901 | LncEditing_221457 | -5.496093e-01 | 3.718902e-06 | 1.301616e-05 |
Cis-expression quantitative trait loci(cis-eQTL) of lncRNA. |
LncRNA Ensembl ID | LncRNA Name | SNP info | Number of Positive corelated Cancer | Positive corelated Cancer | Number of Negative corelated Cancer | Negative corelated Cancer |
lncRNA regulates differentially expressed genes by function as enhancer. |
LncRNA Ensembl ID | PC Gene ID | PC Gene Name | Positive correlated cancers | Cancer with PC gene up-regulation | Cancer with PC gene down-regulation |
LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5). |
lncRNA ID | TF ID | TF Name | PCgene ID | PCgene Name | Number of Cancer | Canaer Types |
LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5). |
lncRNA ID | TF ID | TF Name | PCgene ID | PCgene Name | Number of Cancer | Canaer Types |
LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region. |
LncRNA Ensembl ID | RBP ID | RBP Gene Name | Exon Skipping ID | Skipped Exon | EX Gene Name | EX Affected TransID | ORF_anno | Cancer Type |
LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region. |
LncRNA Ensembl ID | RBP ID | RBP Gene Name | Exon Skipping ID | Skipped Exon | EX Gene Name | EX Affected TransID | ORF_anno | Cancer Type |
lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region. |
LncRNA Ensembl ID | LncRNA ENST ID | PC Gene Name | PC Gene ID | PC ENST ID | dG | nDG | Cancer with PC gene up-regulation | Cancer with PC gene Down-regulation |
lncRNA regulates mRNA by competing the miRNA binding site with mRNA. |
LncRNA Ensembl ID | lncRNA-miRNA-mRNA | Cancer Types |
ORFfinder result for the gencode.v22.lncRNA.transcript.fa. |
lncRNA Ensembl ID | lncRNA ENST ID | length(AA) | start at transcript | end at transcript | ENSG00000233901.4 | ENST00000436710.4 | 145 | 435 | 1 | ENSG00000233901.4 | ENST00000444125.1 | 112 | 564 | 899 | ENSG00000233901.4 | ENST00000423122.1 | 133 | 381 | 782 |
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