lncRNAfunc Logo

Home

Download

Statistics

Landscape

Help

Contact

Center for Computational Systems Medicine
leaf

lncRNA summary

leaf

lncRNA structure and expression level

leaf

lncRNA-Protein interaction

leaf

lncRNA-DNA interaction

leaf

lncRNA-RNA interaction

leaf

Variants in lncRNA

leaf

lncRNAs regulate the target genes through functioning as enhancers

leaf

lncRNAs regulate the target genes through recruiting transcript factors

leaf

lncRNAs regulate the alternative splicing events through interacting with splicing factor

leaf

lncRNAs regulate mRNA through targeting the 3'-UTR region

leaf

lncRNAs regulate mRNA by competing with miRNA

leaf

lncRNA coding potential

lncRNA: ENSG00000230733

Summary for AC092171.4

check button Gene summary

Gene informationEnsembl ID

ENSG00000230733

Gene symbol

AC092171.4

Gene name
HGNC
Entrez ID
Gene typelincRNA
Synonyms
UniProtAcc

Top

Structure and expression level for AC092171.4

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002307338.850512e+02-1.256780e+002.583988e-01-4.863720e+001.150000e-069.350000e-06DOWNGBM
ENSG000002307333.757058e+022.112763e+002.561973e-018.246624e+001.630000e-165.080000e-15UPCHOL
ENSG000002307334.048405e+022.592815e+001.524941e-011.700272e+017.840000e-653.010000e-62UPLIHC

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002307334.415902e-015.813311e-05ACC1.451341e-03
ENSG000002307334.787008e-018.797520e-04CHOL1.535003e-03
ENSG000002307334.853138e-011.433752e-06KICH3.904068e-06
ENSG000002307334.189828e-011.957157e-18LIHC8.355553e-17

Top

lncRNA-Protein interaction for AC092171.4

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000230733ENST00000444210AC092171.4ENSG00000089094KDM2B52.395.4718Q8NHM5TF,EpiPredict
ENSG00000230733ENST00000444210AC092171.4ENSG00000071655MBD314.891.5533O95983TF,EpiChIP-seq

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000230733ENST00000444210AC092171.4ENSG00000176182MYPOP69.9692.0003Q86VE0TFNA
ENSG00000230733ENST00000444210AC092171.4ENSG00000100207TCF2053.5594.3797Q9UGU0TFNA
ENSG00000230733ENST00000444210AC092171.4ENSG00000099326MZF153.2690.6921P28698TFChIP-seq
ENSG00000230733ENST00000444210AC092171.4ENSG00000089094KDM2B52.395.5885Q8NHM5TF,EpiPredict
ENSG00000230733ENST00000444210AC092171.4ENSG00000011451WIZ50.0295.139O95785TFPredict
ENSG00000230733ENST00000444210AC092171.4ENSG00000167967E4F148.9391.8219Q66K89TFNA
ENSG00000230733ENST00000444210AC092171.4ENSG00000106571GLI347.3996.7908P10071TFPredict
ENSG00000230733ENST00000444210AC092171.4ENSG00000100426ZBED446.5990.9532O75132TFChIP-seq
ENSG00000230733ENST00000444210AC092171.4ENSG00000146676PURB37.2993.0613Q96QR8TFNA
ENSG00000230733ENST00000444210AC092171.4ENSG00000177030DEAF130.8190.8791O75398TFNA
ENSG00000230733ENST00000444210AC092171.4ENSG00000101190TCFL527.2491.4887Q9UL49TFNA
ENSG00000230733ENST00000444210AC092171.4ENSG00000197951ZNF7126.7291.7457Q9NQZ8TFNA
ENSG00000230733ENST00000444210AC092171.4ENSG00000185670ZBTB320.8194.2621Q9H5J0TFPredict
ENSG00000230733ENST00000444210AC092171.4ENSG00000166526ZNF320.3591.2673P17036TFNA
ENSG00000230733ENST00000444210AC092171.4ENSG00000071655MBD314.891.5346O95983TF,EpiChIP-seq
ENSG00000230733ENST00000444210AC092171.4ENSG00000275111ZNF27.1791.4355Q9BSG1TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000230733ENST00000444210AC092171.4ENSG00000084072PPIE65.4992.5945Q9UNP9RBPNA
ENSG00000230733ENST00000444210AC092171.4ENSG00000134815DHX3455.9390.8775Q14147RBPNA
ENSG00000230733ENST00000444210AC092171.4ENSG00000123064DDX5455.0294.828Q8TDD1RBPPredict
ENSG00000230733ENST00000444210AC092171.4ENSG00000165271NOL653.4990.3689Q9H6R4RBPNA
ENSG00000230733ENST00000444210AC092171.4ENSG00000100296THOC548.0893.7019Q13769RBPNA
ENSG00000230733ENST00000444210AC092171.4ENSG00000127993RBM4847.9894.0751Q5RL73RBPNA
ENSG00000230733ENST00000444210AC092171.4ENSG00000089280FUS42.3195.4862P35637RBPHITS-CLIP,High-throughput data
ENSG00000230733ENST00000444210AC092171.4ENSG00000106344RBM2836.8692.6359Q9NW13RBPNA
ENSG00000230733ENST00000444210AC092171.4ENSG00000129351ILF336.495.273Q12906RBPENCODE
ENSG00000230733ENST00000444210AC092171.4ENSG00000148840PPRC129.0496.6587Q5VV67RBPPredict
ENSG00000230733ENST00000444210AC092171.4ENSG00000105671DDX4911.492.1442Q9Y6V7RBPNA
ENSG00000230733ENST00000444210AC092171.4ENSG00000205937RNPS19.8190.4615Q15287RBPNA

Top

lncRNA-DNA interaction for AC092171.4

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
ZNF30,RBM19,DNMT1,ILF3,GLI4,EDC3,MYPOP,IRF3,DDX56,TIGD5,MZF1,NRF1,PHF19,RBM23,ZNF2,MAFG,MAZ,GLI3,CENPB,RBM28,ZNF74,DDX24,ZBED4,KMT2B,SAFB2,NOP9,MNT,CNOT4,TFAP4,LSM5,EIF3G,NOL6,SUGP1,PUF60,DDX54,LSM4,CREB3,U2AF2,TCFL5,CPSF1,RNPS1,RBM14,PURB,ZBTB3,ADNP,SURF6,NFYC,DHX34,CPSF4,PPIE,TCF20,CXXC1,ZNF71,PATZ1,CSTF1,PUS7,HSF1,ZHX3,MECP2,DEAF1,TGIF2,DDX49,TTF1,NOL9,RBM42,FOXM1,KLF16,ZNF48,SGSM2,CENPA,WIZ,REXO4,RBM10,DDX51,E2F4,MBD3,PCBP4,THAP3,APEX1,DDX31,FIZ1,EIF3B,PREB,ZNF3,SOX12,KDM2B,CPSF3,RBM48,E2F1,GMEB2,XPO1,THAP8,DOT1L,PIN1,THOC5,RXRB,RBM8A,CSTF2,NACC2,NAIF1,DDX41,USF2,SFPQ,RALY,XPO5
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.
Only predicted by TDF
AGO1,SFPQ,DOT1L,THOC5,ZNF48,MZF1,EIF3G,MLXIP,CENPB,MECP2,E4F1,PUS7,CXXC1,U2AF2,PHF19,THAP7,TFAP4,ZNF3,RBM19,FOXK1,DNMT1,E2F4,RBM42,MYPOP,DHX30,WIZ,ZNF71,USF2,ZNF30,FOXK2,THAP3,CENPA
Exist in public source
NA

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

Top

lncRNA-RNA interaction for AC092171.4

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
SP100,ATF3
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000230733ENST00000444210exon_skip_136020chr16:31186801-31186836-10.18-0.9255FUSENST00000254108Frame-shift
ENSG00000230733ENST00000444210exon_skip_378467chr3:143023974-143024018-9.48-0.2873U2SURPENST00000473835Frame-shift
ENSG00000230733ENST00000444210exon_skip_353171chr20:58898940-58898985-13.96-0.4106GNASENST00000371085,ENST00000371100In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000230733ENST00000444210exon_skip_476029chr7:65974918-65975071-20.68-0.1436GUSBENST00000304895In-frame

check buttonlncRNA targets by miRNA.
lncRNA targets by miRNA
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5477762-5477855216.00-84.4091NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5476012-5476108186.00-94.2193NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5475878-5475961185.00-81.6577NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5478431-5478522183.00-83.0482NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5478189-5478282182.00-75.0389NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5478856-5478942182.00-93.7276NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5477987-5478077181.00-83.2388NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5477634-5477714180.00-85.4383NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5477108-5477187179.00-87.0272NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5478565-5478645178.00-84.6383NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5477435-5477523175.00-93.9088NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5478287-5478367173.00-72.4784NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5476401-5476495171.00-84.8893NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5478763-5478851171.00-92.7280NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5476313-5476409169.00-96.0194NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5478646-5478732169.00-86.3390NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5477325-5477419167.00-87.3695NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5477913-5477996165.00-74.1079NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5477002-5477097163.00-91.4592NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5478953-5479041163.00-89.9387NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5475805-5475894161.00-69.4287NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5477527-5477616160.00-91.0781NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5476802-5476884158.00-84.5883NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5476525-5476614153.00-79.4391NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5478076-5478164153.00-86.0489NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5476650-5476751150.00-90.2697NA
ENSG00000230733hsa-mir-3614ENST00000444210chr7:5477202-5477285147.00-93.3584NA

Top

Variants for AC092171.4

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

Top

lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

Top

lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types
ENSG00000230733ENSG00000071655MBD3ENSG00000100296THOC56ACC,CHOL,LIHC,MESO,PAAD,THYM
ENSG00000230733ENSG00000071655MBD3ENSG00000180035ZNF489CHOL,COAD,GBM,KICH,LAML,LIHC,PAAD,PCPG,THYM
ENSG00000230733ENSG00000166526ZNF3ENSG00000180035ZNF485CHOL,KICH,LIHC,PCPG,PRAD
ENSG00000230733ENSG00000167967E4F1ENSG00000180035ZNF485CHOL,COAD,GBM,KICH,LAML
ENSG00000230733ENSG00000176182MYPOPENSG00000180035ZNF486CHOL,COAD,KICH,LIHC,PAAD,PCPG
ENSG00000230733ENSG00000177030DEAF1ENSG00000180035ZNF485CHOL,COAD,GBM,KICH,LIHC
ENSG00000230733ENSG00000185670ZBTB3ENSG00000180035ZNF486CHOL,KICH,LAML,LIHC,PAAD,PCPG
ENSG00000230733ENSG00000197951ZNF71ENSG00000180035ZNF485CHOL,KICH,LAML,PAAD,PCPG
ENSG00000230733ENSG00000071655MBD3ENSG00000130811EIF3G5CHOL,COAD,LIHC,PCPG,THYM
ENSG00000230733ENSG00000071655MBD3ENSG00000125817CENPB8CHOL,COAD,KICH,LIHC,MESO,PAAD,PCPG,THYM
ENSG00000230733ENSG00000176182MYPOPENSG00000125817CENPB6CHOL,COAD,KICH,LIHC,PAAD,PCPG
ENSG00000230733ENSG00000071655MBD3ENSG00000167967E4F16CHOL,COAD,GBM,KICH,LAML,THYM
ENSG00000230733ENSG00000071655MBD3ENSG00000154832CXXC18CHOL,COAD,GBM,LAML,LIHC,LUAD,PAAD,THYM
ENSG00000230733ENSG00000011451WIZENSG00000063244U2AF25CHOL,COAD,LAML,LIHC,PCPG
ENSG00000230733ENSG00000071655MBD3ENSG00000119403PHF195ACC,CHOL,COAD,LIHC,STAD
ENSG00000230733ENSG00000071655MBD3ENSG00000184436THAP75CHOL,KICH,LIHC,PAAD,THYM
ENSG00000230733ENSG00000185670ZBTB3ENSG00000166526ZNF35CHOL,KICH,KIRP,LIHC,PCPG
ENSG00000230733ENSG00000011451WIZENSG00000164916FOXK16CHOL,GBM,KICH,LAML,LIHC,PCPG
ENSG00000230733ENSG00000100207TCF20ENSG00000164916FOXK15ACC,CHOL,GBM,KICH,LIHC
ENSG00000230733ENSG00000100426ZBED4ENSG00000164916FOXK15CHOL,KIRC,LIHC,MESO,OV
ENSG00000230733ENSG00000146676PURBENSG00000164916FOXK18ACC,CHOL,ESCA,GBM,HNSC,KIRP,LIHC,LUSC
ENSG00000230733ENSG00000166526ZNF3ENSG00000164916FOXK16ACC,CHOL,KICH,KIRP,LIHC,PCPG
ENSG00000230733ENSG00000011451WIZENSG00000130816DNMT15CHOL,COAD,GBM,LIHC,LUAD
ENSG00000230733ENSG00000100207TCF20ENSG00000130816DNMT15ACC,CHOL,GBM,KICH,LIHC
ENSG00000230733ENSG00000071655MBD3ENSG00000126254RBM426CHOL,COAD,KICH,LIHC,READ,THYM
ENSG00000230733ENSG00000071655MBD3ENSG00000176182MYPOP7CHOL,COAD,KICH,LIHC,PAAD,PCPG,THYM
ENSG00000230733ENSG00000177030DEAF1ENSG00000176182MYPOP5CHOL,COAD,GBM,KICH,LIHC
ENSG00000230733ENSG00000011451WIZENSG00000132153DHX306CHOL,COAD,GBM,KICH,LAML,LIHC
ENSG00000230733ENSG00000176182MYPOPENSG00000132153DHX305CHOL,COAD,GBM,LIHC,PAAD
ENSG00000230733ENSG00000197951ZNF71ENSG00000132153DHX305CHOL,KICH,LAML,PAAD,TGCT
ENSG00000230733ENSG00000071655MBD3ENSG00000105698USF27CHOL,COAD,LIHC,PAAD,PCPG,READ,THYM
ENSG00000230733ENSG00000176182MYPOPENSG00000105698USF26CHOL,COAD,KICH,LIHC,PAAD,PCPG

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

Top

lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

Top

lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

Top

lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types
ENSG00000230733AC092171.4,hsa-mir-3614,MEGF8UCEC,SKCM,CHOL,UCS,PAAD,LIHC
ENSG00000230733AC092171.4,hsa-mir-3614,VAPBUCEC,SKCM,CHOL,UCS,LIHC
ENSG00000230733AC092171.4,hsa-mir-3614,UNC119BUCEC,SKCM,CHOL,PAAD,LIHC
ENSG00000230733AC092171.4,hsa-mir-3614,FAM168BUCEC,SKCM,CHOL,UCS,LIHC

Top

lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000230733.2ENST00000444210.217852588