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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000230061

Summary for TRPM2-AS

check button Gene summary

Gene informationEnsembl ID

ENSG00000230061

Gene symbol

TRPM2-AS

Gene nameTRPM2 antisense RNA
HGNC

50758

Entrez ID
Gene typeantisense
SynonymsTRPM2-AS|21q22.3
UniProtAcc

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Structure and expression level for TRPM2-AS

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002300612.184523e+022.888643e+004.865072e-015.937514e+002.890000e-094.540000e-08UPBLCA
ENSG000002300612.194984e+023.400623e+002.204036e-011.542908e+011.040000e-531.380000e-51UPUCEC
ENSG000002300611.362303e+022.221262e+003.327801e-016.674864e+002.470000e-112.050000e-10UPPRAD
ENSG000002300611.479996e+024.707108e+002.619401e-011.797017e+013.340000e-721.680000e-70UPLUSC
ENSG000002300612.281729e+021.387473e+001.711894e-018.104900e+005.280000e-162.820000e-15UPBRCA
ENSG000002300611.481973e+023.183054e+002.556078e-011.245288e+011.350000e-355.090000e-34UPCOAD
ENSG000002300612.517725e+023.067200e+003.194381e-019.601860e+007.850000e-227.070000e-20UPSTAD
ENSG000002300611.587811e+024.950191e+005.327433e-019.291886e+001.520000e-203.500000e-18UPREAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002300613.621160e-011.256406e-19UCEC5.304831e-18

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lncRNA-Protein interaction for TRPM2-AS

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000230061ENST00000456880TRPM2-ASENSG00000100429HDAC1044.7592.3037Q969S8EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for TRPM2-AS

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
ANKS3,RBBP8NL,TRPM2,NEK8,CCNL2,C21orf58,CCDC24,C1orf159,FBXL6,CNKSR1,SETD4,CAPN10,NDUFV3,CFAP298,DUS1L,RABEP2,RTKN,HDAC10,RHPN1,NAT9
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for TRPM2-AS

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for TRPM2-AS

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation
ENSG00000230061ENSG00000109065NAT9BLCA,COAD,ESCA,STAD,UCSCOAD
ENSG00000230061ENSG00000130701RBBP8NLBLCA,COAD,READ,STAD,UCEC,UCSBLCA,COAD,READ,UCEC
ENSG00000230061ENSG00000142185TRPM2BLCA,BRCA,COAD,ESCA,LAML,LUSC,OV,PRAD,READ,SKCM,STAD,UCEC,UCS,UVMBLCA,BRCA,COAD,LUSC,PRAD,READ,STAD,UCEC
ENSG00000230061ENSG00000142675CNKSR1BLCA,OV,STAD,UCEC,UCSBLCA,UCEC
ENSG00000230061ENSG00000158106RHPN1BLCA,COAD,ESCA,STAD,UCS,UVMBLCA,COAD,STAD
ENSG00000230061ENSG00000182325FBXL6BLCA,READ,STAD,UCS,UVMBLCA,READ
ENSG00000230061ENSG00000221978CCNL2BLCA,COAD,ESCA,UCEC,UCSBLCA
ENSG00000230061ENSG00000114993RTKNCOAD,ESCA,LUSC,STAD,UCSCOAD,LUSC

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000230061.2ENST00000423310.2124156527
ENSG00000230061.2ENST00000456880.112826412