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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000227199

Summary for ST7-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000227199

Gene symbol

ST7-AS1

Gene nameST7 antisense RNA 1
HGNC

16000

Entrez ID

93653

Gene typeantisense
Synonyms07q31.2|ST7-AS1
UniProtAcc

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Structure and expression level for ST7-AS1

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002271992.214516e+021.488987e+003.360165e-014.431290e+009.370000e-066.050000e-05UPGBM
ENSG000002271991.924199e+02-1.436237e+001.049687e-01-1.368252e+011.290000e-428.250000e-41DOWNTHCA
ENSG000002271991.364387e+02-1.105860e+001.651184e-01-6.697379e+002.120000e-111.430000e-10DOWNKICH

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG00000227199-5.504402e-012.294449e-08KICH1.107381e-07
ENSG00000227199-3.098942e-014.600265e-14THCA5.378251e-13

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lncRNA-Protein interaction for ST7-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for ST7-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
CTNNBIP1,WRAP73,MORN2,DUT,ARL16,NELFB,PRPSAP2,POMT1,CIRBP,STMP1,WDR83OS,NRF1,RRNAD1,LYSMD4,KAT8,BCS1L,MKS1,TRAPPC12,OSCP1,BCL7C,BIVM,ZCWPW1,C20orf96,SNRPA,NARF,LSM5,INTS11,NT5C3B,CENPT,STX10,NAA80,CDK20,LRRC23,CSTF3,ECHDC2,CYB5D2,BEND5,SPATA6,NFIA,ENDOV,SSU72,CEP89,METTL23,GLT8D1,CXXC1,ZNF34,ERMARD,TRIM45,ACYP1,ANKS3,RBM42,PEX11G,PDAP1,TIGD1,MBD3,PEMT,ARMC7,MOSPD3,GEMIN2,HMGN1,TTC32,TSEN54,VPS4A,NSUN6,ZNF3,TMEM218,CZIB,SYF2,LNP1,RPA3,C14orf93,DPH7,PSME3IP1,NSMCE4A,NDUFV3,DGCR6L,XPA,PLXNB1,ERCC5,ACAP3,IQCC
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for ST7-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000227199ENST00000456775exon_skip_421737chr4:3428557-3428711-16.56-0.1191RGS12ENST00000336727,ENST00000344733Frame-shift

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000227199ENST00000456775exon_skip_111863chr14:23565815-23565892-16.10-0.2368AP1G2ENST00000308724,ENST00000397120Frame-shift
ENSG00000227199ENST00000456775exon_skip_494079chr8:144099080-144099205-31.13-0.2937SHARPINENST00000398712Frame-shift

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for ST7-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation
ENSG00000227199ENSG00000104915STX10ACC,GBM,KICH,KIRP,LGGGBM
ENSG00000227199ENSG00000125449ARMC7ACC,GBM,KICH,KIRP,LGGKICH
ENSG00000227199ENSG00000188010MORN2ACC,KICH,KIRP,THCA,UVMKICH
ENSG00000227199ENSG00000205581HMGN1ACC,GBM,KICH,KIRP,LGGGBM
ENSG00000227199ENSG00000011143MKS1GBM,KICH,KIRP,LGG,THCA,UCS,UVMGBM
ENSG00000227199ENSG00000106330MOSPD3GBM,KICH,KIRP,LGG,SKCM,THYM,UCSGBM
ENSG00000227199ENSG00000164050PLXNB1GBM,KICH,KIRP,THYM,UVMKICH
ENSG00000227199ENSG00000206535LNP1GBM,KICH,KIRP,THCA,UCS,UVMKICH
ENSG00000227199ENSG00000116885OSCP1KICH,KIRP,SKCM,THCA,THYM,UVMKICH
ENSG00000227199ENSG00000121310ECHDC2KICH,KIRP,THCA,THYM,UVMKICH
ENSG00000227199ENSG00000132122SPATA6KICH,KIRP,THCA,THYM,UVMKICH
ENSG00000227199ENSG00000150433TMEM218KICH,KIRP,THCA,UCS,UVMKICH
ENSG00000227199ENSG00000162373BEND5KICH,OV,THYM,UCEC,UVMKICH

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000227199.1ENST00000456775.157458285