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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000225969

Summary for ABHD11-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000225969

Gene symbol

ABHD11-AS1

Gene nameABHD11 antisense RNA 1 (tail to tail)
HGNC

18289

Entrez ID
Gene typeantisense
SynonymsABHD11-AS1|07q11.23
UniProtAcc

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Structure and expression level for ABHD11-AS1

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002259696.408061e+014.461268e+007.745341e-015.759938e+008.410000e-098.030000e-08UPCHOL
ENSG000002259692.083410e+022.012594e+002.111177e-019.533044e+001.530000e-212.440000e-20UPTHCA
ENSG000002259699.566132e+012.483817e+001.772687e-011.401159e+011.320000e-442.570000e-43UPKIRC
ENSG000002259691.567844e+021.571338e+004.567504e-013.440256e+005.811650e-042.402828e-03UPBLCA
ENSG000002259691.603049e+023.217289e+002.701556e-011.190902e+011.060000e-329.040000e-31UPKIRP
ENSG000002259699.457339e+012.048449e+002.831013e-017.235744e+004.630000e-134.020000e-12UPUCEC
ENSG000002259695.778078e+01-1.497218e+002.044166e-01-7.324347e+002.400000e-131.060000e-12DOWNLUSC
ENSG000002259697.875756e+011.428063e+001.554382e-019.187333e+004.030000e-202.610000e-19UPBRCA
ENSG000002259692.888779e+02-1.333530e+002.122575e-01-6.282602e+003.330000e-101.900000e-09DOWNCOAD
ENSG000002259692.222171e+02-1.115312e+002.777117e-01-4.016077e+005.920000e-052.633530e-04DOWNSTAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002259693.596086e-011.525690e-02CHOL1.703991e-02

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lncRNA-Protein interaction for ABHD11-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for ABHD11-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for ABHD11-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
CNOT1,PREPL,FAM168B,DSTYK,NEK4,METTL14,PHF6,FAM53C,GSK3B,QKI,ARID1A,ZFYVE16,YLPM1,NAF1,ZMYND11,SENP2,EIF4G3,RDX,TOP2B,DNAJC16,STX17,UBR1,CHD8,S100PBP,FOXJ3,HBS1L,PNPT1,TRIM37,PTPN11,KAT6B,RCHY1,RNF214,PRDM2,HECTD1,NEDD1,IARS1,TUT4,PBRM1,TASOR,ELOA,DNAJC11,HELZ,CLTC,ATRN,MAN1A2,PCYOX1,GMPS,ZFP1,FUBP1,SNX19,CSDE1,KTN1,RIOX2,USP33,ARID1B,PCNX1,TP53BP1,WDR48,STAM,UBR4,SDAD1,KIDINS220,CDC27,NEK9,TFCP2,SMARCA2,CLASP2,APPBP2,TCHP,CLCC1,CCSER2,SLTM,MCC,MTMR12,SUGP2,MFSD14A,SMAD1,ZBED3,POLR2B,PIKFYVE,SSR1,MKRN2,MDC1,C1orf109,UEVLD,DYNC1LI2,KBTBD4,YAP1,C2CD3,MED13,WDR7,SENP6,SSH1,UVRAG,OSBPL8,USP46,ARMC8,SEPTIN2,INVS,KAT7,KLHL5,SIK3,NUP98,KIAA0586,DNAJC24,AZI2,FAM120B,DCAF7,GTF3C4,GTF2A1,ECPAS,RABGAP1,TNPO1,GTF2I,SMAD5,EMSY,EIF4G2,SOS2,THRAP3,LARS2,CLASP1,SEC22C,NCAPD3,GOSR1,PRKAR1A,RANBP2,DCAF17,MAP3K4,RPE,TAF2,TMEM184C,TEX2,RAD17,PLAA,KANSL3,FAM114A2,RABEP1,MED23,EIF2AK4,CPSF2,ATF1,CELF1,CANX,DOCK1,BCKDHB,LATS1,DHX36,HERC1,MCFD2,IBTK,NCAPD2,ZFYVE9,NSD1,SLC39A6,SLC25A51,RAB6A
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000225969ENST00000427153exon_skip_44853chr10:104010815-104010908-14.00-0.1522SLKENST00000369755In-frame
ENSG00000225969ENST00000427153exon_skip_59476chr11:57815914-57816001-14.43-0.2091CTNND1ENST00000399050In-frame
ENSG00000225969ENST00000427153exon_skip_114200chr14:73279280-73279424-26.93-0.2207NUMBENST00000355058,ENST00000555238In-frame
ENSG00000225969ENST00000427153exon_skip_150188chr17:27643524-27643620-14.26-0.1805LGALS9ENST00000395473In-frame
ENSG00000225969ENST00000427153exon_skip_386291chr3:108050577-108050602-6.46-0.3589CD47ENST00000361309Frame-shift
ENSG00000225969ENST00000427153exon_skip_423795chr4:55888887-55888932-7.79-0.2291EXOC1ENST00000346134,ENST00000381295In-frame
ENSG00000225969ENST00000427153exon_skip_435063chr5:66075023-66075230-17.89-0.1016ERBINENST00000284037In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000225969ENST00000427153exon_skip_90104chr12:10709907-10710114-30.59-0.1672YBX3ENST00000228251In-frame
ENSG00000225969ENST00000427153exon_skip_337919chr2:27445744-27445843-12.35-0.1403IFT172ENST00000260570In-frame
ENSG00000225969ENST00000427153exon_skip_351122chr20:36209487-36209898-42.61-0.1065EPB41L1ENST00000338074In-frame
ENSG00000225969ENST00000427153exon_skip_382356chr3:37091466-37091538-13.63-0.2963LRRFIP2ENST00000336686In-frame
ENSG00000225969ENST00000427153exon_skip_460899chr6:85538837-85538864-3.99-0.2347SNX14ENST00000314673In-frame
ENSG00000225969ENST00000427153exon_skip_470719chr7:117134123-117134192-8.84-0.1449ST7ENST00000265437In-frame
ENSG00000225969ENST00000427153exon_skip_300058chr18:79933968-79934022-12.18-0.3691PQLC1ENST00000397778In-frame
ENSG00000225969ENST00000427153exon_skip_514511chrX:41555599-41555635-7.42-0.3092CASKENST00000378163In-frame

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for ABHD11-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation
ENSG00000225969ENST00000427153BCKDHBENSG00000083123ENST00000369760-0.228295-CHOL,KIRC
ENSG00000225969ENST00000427153BCKDHBENSG00000083123ENST00000356489-0.11391-CHOL,KIRC
ENSG00000225969ENST00000427153PCYOX1ENSG00000116005ENST00000433351-0.11511-CHOL,KIRP,BRCA
ENSG00000225969ENST00000427153SMARCA2ENSG00000080503ENST00000382186-0.8200462-CHOL,KIRP,UCEC
ENSG00000225969ENST00000427153MCCENSG00000171444ENST00000624689-0.1046287-CHOL,KIRP,UCEC
ENSG00000225969ENST00000427153MCCENSG00000171444ENST00000514701-0.39101-CHOL,KIRP,UCEC
ENSG00000225969ENST00000427153ZFYVE9ENSG00000157077ENST00000357206-0.1278347-KIRP
ENSG00000225969ENST00000427153USP46ENSG00000109189ENST00000508499-0.2747507-KIRC,KIRP
ENSG00000225969ENST00000427153USP46ENSG00000109189ENST00000512656-0.2232293-KIRC,KIRP
ENSG00000225969ENST00000427153NCAPD3ENSG00000151503ENST00000526422-0.1035265LUSC,COAD,STAD-
ENSG00000225969ENST00000427153RIOX2ENSG00000170854ENST00000514314-0.1227273-KIRC,KIRP
ENSG00000225969ENST00000427153IARS1ENSG00000196305ENST00000375627-0.1258379COAD-
ENSG00000225969ENST00000427153DNAJC11ENSG00000007923ENST00000377577-0.11801-KIRC,KIRP
ENSG00000225969ENST00000427153DNAJC11ENSG00000007923ENST00000451196-0.1039102-KIRC,KIRP
ENSG00000225969ENST00000427153LARS2ENSG00000011376ENST00000414984-0.5482399-CHOL,KIRC

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000225969.1ENST00000427153.114920301581