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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000225265

Summary for TAF1A-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000225265

Gene symbol

TAF1A-AS1

Gene nameTAF1A antisense RNA 1
HGNC

40573

Entrez ID

100506161

Gene typeantisense
SynonymsTAF1A-AS1|01q41
UniProtAcc

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Structure and expression level for TAF1A-AS1

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002252651.408407e+021.383275e+003.181420e-014.347978e+001.370000e-058.490000e-05UPGBM
ENSG000002252659.959311e+01-1.345205e+001.738969e-01-7.735650e+001.030000e-149.950000e-14DOWNKICH
ENSG000002252658.552567e+011.175927e+001.225354e-019.596633e+008.260000e-225.920000e-21UPLUSC
ENSG000002252657.021274e+011.030315e+001.231584e-018.365775e+005.970000e-174.840000e-16UPLUAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG00000225265-5.716990e-014.868354e-09KICH3.018379e-08

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lncRNA-Protein interaction for TAF1A-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for TAF1A-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for TAF1A-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
MAP1S,FMNL1,GRAMD1A,MOB3A,FLNA,IL4R,TNFRSF1A,TRPV2,SBNO2,SIPA1,MYADM,EMP3,RIN3,MVP,ADGRE5,ITGA5,FZR1,PLEKHG2,PLXND1
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for TAF1A-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation
ENSG00000225265ENST00000441835MAP1SENSG00000130479ENST00000324096-0.1879292-GBM
ENSG00000225265ENST00000441835MAP1SENSG00000130479ENST00000600608-0.11051-GBM
ENSG00000225265ENST00000441835MAP1SENSG00000130479ENST00000544059-0.4656318-GBM
ENSG00000225265ENST00000441835MAP1SENSG00000130479ENST00000593593-0.100777-GBM
ENSG00000225265ENST00000441835MAP1SENSG00000130479ENST00000596637-0.117297-GBM
ENSG00000225265ENST00000441835MAP1SENSG00000130479ENST00000597000-0.1496295-GBM
ENSG00000225265ENST00000441835MYADMENSG00000179820ENST00000391768-0.10668-LUSC,LUAD
ENSG00000225265ENST00000441835FMNL1ENSG00000184922ENST00000586643-0.4940143-GBM,LUSC
ENSG00000225265ENST00000441835TRPV2ENSG00000187688ENST00000338560-0.127581-LUSC,LUAD
ENSG00000225265ENST00000441835TRPV2ENSG00000187688ENST00000577277-0.107781-LUSC,LUAD
ENSG00000225265ENST00000441835TRPV2ENSG00000187688ENST00000581560-0.129181-LUSC,LUAD
ENSG00000225265ENST00000441835TRPV2ENSG00000187688ENST00000580788-0.107781-LUSC,LUAD
ENSG00000225265ENST00000441835TRPV2ENSG00000187688ENST00000577865-0.107783-LUSC,LUAD
ENSG00000225265ENST00000441835EMP3ENSG00000142227ENST00000270221-0.197311-LUSC,LUAD
ENSG00000225265ENST00000441835EMP3ENSG00000142227ENST00000596315-0.197311-LUSC,LUAD
ENSG00000225265ENST00000441835EMP3ENSG00000142227ENST00000597279-0.197311-LUSC,LUAD
ENSG00000225265ENST00000427540RIN3ENSG00000100599ENST00000557762-0.1250117-LUSC
ENSG00000225265ENST00000427540MAP1SENSG00000130479ENST00000324096-0.5295588-GBM
ENSG00000225265ENST00000427540MAP1SENSG00000130479ENST00000544059-0.1985105-GBM
ENSG00000225265ENST00000427540MAP1SENSG00000130479ENST00000593593-0.1256112-GBM
ENSG00000225265ENST00000427540MAP1SENSG00000130479ENST00000597000-0.5295591-GBM
ENSG00000225265ENST00000427540FMNL1ENSG00000184922ENST00000586643-2.2800142-GBM,LUSC
ENSG00000225265ENST00000427540TRPV2ENSG00000187688ENST00000338560-0.164139-LUSC,LUAD
ENSG00000225265ENST00000427540TRPV2ENSG00000187688ENST00000581560-0.131839-LUSC,LUAD
ENSG00000225265ENST00000427540EMP3ENSG00000142227ENST00000270221-0.1212142-LUSC,LUAD
ENSG00000225265ENST00000427540EMP3ENSG00000142227ENST00000596315-0.1212142-LUSC,LUAD
ENSG00000225265ENST00000427540EMP3ENSG00000142227ENST00000597279-0.1212142-LUSC,LUAD
ENSG00000225265ENST00000413074RIN3ENSG00000100599ENST00000557762-0.1250381-LUSC
ENSG00000225265ENST00000413074ADGRE5ENSG00000123146ENST00000358600-0.136041-LUSC,LUAD
ENSG00000225265ENST00000413074MAP1SENSG00000130479ENST00000324096-0.336136-GBM
ENSG00000225265ENST00000413074MAP1SENSG00000130479ENST00000600608-0.1310119-GBM
ENSG00000225265ENST00000413074MAP1SENSG00000130479ENST00000544059-0.336162-GBM
ENSG00000225265ENST00000413074MAP1SENSG00000130479ENST00000593593-0.1256376-GBM
ENSG00000225265ENST00000413074MAP1SENSG00000130479ENST00000597000-0.336139-GBM
ENSG00000225265ENST00000413074FMNL1ENSG00000184922ENST00000586643-2.2800406-GBM,LUSC
ENSG00000225265ENST00000413074TRPV2ENSG00000187688ENST00000338560-0.1641303-LUSC,LUAD
ENSG00000225265ENST00000413074TRPV2ENSG00000187688ENST00000581560-0.1017108-LUSC,LUAD
ENSG00000225265ENST00000413074EMP3ENSG00000142227ENST00000270221-0.254360-LUSC,LUAD
ENSG00000225265ENST00000413074EMP3ENSG00000142227ENST00000596315-0.254360-LUSC,LUAD
ENSG00000225265ENST00000413074EMP3ENSG00000142227ENST00000597279-0.254360-LUSC,LUAD

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000225265.1ENST00000441835.1742221
ENSG00000225265.1ENST00000427540.16822923
ENSG00000225265.1ENST00000413074.1541632