lncRNAfunc Logo

Home

Download

Statistics

Landscape

Help

Contact

Center for Computational Systems Medicine
leaf

lncRNA summary

leaf

lncRNA structure and expression level

leaf

lncRNA-Protein interaction

leaf

lncRNA-DNA interaction

leaf

lncRNA-RNA interaction

leaf

Variants in lncRNA

leaf

lncRNAs regulate the target genes through functioning as enhancers

leaf

lncRNAs regulate the target genes through recruiting transcript factors

leaf

lncRNAs regulate the alternative splicing events through interacting with splicing factor

leaf

lncRNAs regulate mRNA through targeting the 3'-UTR region

leaf

lncRNAs regulate mRNA by competing with miRNA

leaf

lncRNA coding potential

lncRNA: ENSG00000224958

Summary for PGM5-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000224958

Gene symbol

PGM5-AS1

Gene namePGM5 antisense RNA 1
HGNC

44181

Entrez ID

572558

Gene typeantisense
Synonyms09q21.11|PGM5-AS1
UniProtAcc

Top

Structure and expression level for PGM5-AS1

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002249581.380185e+02-5.158228e+008.736667e-01-5.904114e+003.550000e-095.460000e-08DOWNBLCA
ENSG000002249583.647924e+01-9.531741e+001.890235e+00-5.042621e+004.590000e-071.270000e-05DOWNCESC
ENSG000002249582.637207e+01-5.451765e+004.557702e-01-1.196165e+015.640000e-332.220000e-31DOWNUCEC
ENSG000002249583.959359e+02-1.711086e+002.478042e-01-6.904992e+005.020000e-124.550000e-11DOWNPRAD
ENSG000002249588.138189e+01-3.592421e+004.814259e-01-7.462044e+008.520000e-142.070000e-12DOWNSTAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG00000224958-3.624645e-014.818650e-04KICH7.087284e-04
ENSG00000224958-3.477487e-014.165742e-17PRAD5.178175e-16
ENSG00000224958-3.961254e-011.713105e-23UCEC1.301960e-20

Top

lncRNA-Protein interaction for PGM5-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

Top

lncRNA-DNA interaction for PGM5-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

Top

lncRNA-RNA interaction for PGM5-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000224958ENST00000417887exon_skip_21628chr1:9756480-9756510-7.48-0.3740CLSTN1ENST00000377298In-frame
ENSG00000224958ENST00000417887exon_skip_43507chr10:84499874-84499959-11.41-0.1375CCSER2ENST00000224756Frame-shift
ENSG00000224958ENST00000417887exon_skip_97739chr12:121244572-121244615-8.80-0.2444CAMKK2ENST00000324774,ENST00000402834,ENST00000404169Frame-shift
ENSG00000224958ENST00000417887exon_skip_104174chr13:79353152-79353224-11.23-0.2612RBM26ENST00000438737In-frame
ENSG00000224958ENST00000417887exon_skip_287874chr17:29085603-29085648-8.87-0.3285MYO18AENST00000527372In-frame
ENSG00000224958ENST00000417887exon_skip_335378chr2:237751199-237751271-8.38-0.2993LRRFIP1ENST00000392000In-frame
ENSG00000224958ENST00000417887exon_skip_436488chr5:96726793-96726859-9.08-0.1489CASTENST00000341926,ENST00000395813In-frame
ENSG00000224958ENST00000417887exon_skip_515330chrX:65524563-65524614-8.47-0.4235LAS1LENST00000374811In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000224958ENST00000417887exon_skip_98384chr12:124327408-124327633-20.52-0.1031NCOR2ENST00000405201In-frame
ENSG00000224958ENST00000417887exon_skip_145776chr16:70665465-70665540-10.49-0.1748MTSS1LENST00000338779In-frame
ENSG00000224958ENST00000417887exon_skip_294566chr17:81683012-81683126-18.03-0.1654ARL16ENST00000397498In-frame

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

Top

Variants for PGM5-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

Top

lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

Top

lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

Top

lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

Top

lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

Top

lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

Top

lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000224958.4ENST00000420855.466187387
ENSG00000224958.4ENST00000417887.1656203