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lncRNA: ENSG00000214293

Summary for APTR

Gene summary

Gene information	Ensembl ID	ENSG00000214293
	Gene symbol	APTR
	Gene name	Alu-mediated CDKN1A/p21 transcriptional regulator
	HGNC	44173
	Entrez ID	100505854
	Gene type	lincRNA
	Synonyms	APTR\|07q11.23
	UniProtAcc

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Structure and expression level for APTR

AS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID

Base mean

log2FC(AD/control)

lfcSE

Stat

P-value

Adjc.p-value

DEG direction

Cancer type

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000214293	4.292206e-01	3.259305e-03	CHOL	4.538205e-03
ENSG00000214293	4.027703e-01	4.939665e-17	LIHC	1.142297e-15

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lncRNA-Protein interaction for APTR

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000214293	ENST00000440088	APTR	ENSG00000083544	TDRD3	31.3	95.6537	Q9H7E2	RBP,Epi	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000116560	SFPQ	42.08	90.1507	P23246	RBP,Epi	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000115966	ATF2	7.58	90.1549	P15336	TF,Epi	ChIP-seq

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000214293	ENST00000440088	APTR	ENSG00000144747	TMF1	85.17	96.3167	P82094	TF	Predict
ENSG00000214293	ENST00000440088	APTR	ENSG00000135164	DMTF1	74.44	90.1656	Q9Y222	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000130254	SAFB2	74.37	96.6227	Q14151	TF,RBP	Predict
ENSG00000214293	ENST00000440088	APTR	ENSG00000105127	AKAP8	66.17	95.7897	O43823	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000099326	MZF1	61.96	91.6446	P28698	TF	ChIP-seq
ENSG00000214293	ENST00000440088	APTR	ENSG00000125482	TTF1	60.23	93.9519	Q15361	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000175197	DDIT3	58.92	92.1465	P35638	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000070476	ZXDC	54.52	93.193	Q2QGD7	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000167232	ZNF91	52.59	96.357	Q05481	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000196670	ZFP62	46.18	92.304	Q8NB50	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000146587	RBAK	44.48	94.0935	Q9NYW8	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000147789	ZNF7	42.79	93.3703	P17097	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000170448	NFXL1	41.53	92.7333	Q6ZNB6	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000198040	ZNF84	39.26	95.1474	P51523	TF	ChIP-seq
ENSG00000214293	ENST00000440088	APTR	ENSG00000171970	ZNF57	34.77	94.2702	Q68EA5	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000169740	ZNF32	33.57	92.7981	P17041	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000186272	ZNF17	32.85	94.1294	P17021	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000142065	ZFP14	32.74	93.0364	Q9HCL3	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000180787	ZFP3	32.66	91.784	Q96NJ6	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000164631	ZNF12	31.79	93.329	P17014	TF	ChIP-seq
ENSG00000214293	ENST00000440088	APTR	ENSG00000119950	MXI1	31.7	92.3134	P50539	TF	ChIP-seq
ENSG00000214293	ENST00000440088	APTR	ENSG00000120784	ZFP30	30.6	93.2005	Q9Y2G7	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000166526	ZNF3	25.58	92.3159	P17036	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000198429	ZNF69	25.55	93.3051	Q9UC07	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000105708	ZNF14	25.5	93.5917	P17017	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000062194	GPBP1	25.17	94.1263	Q86WP2	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000256223	ZNF10	24.21	93.7826	P21506	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000197857	ZNF44	23.41	95.1774	P15621	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000184939	ZFP90	23.35	92.6271	Q8TF47	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000125850	OVOL2	21.72	90.7243	Q9BRP0	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000168661	ZNF30	21.62	94.3515	P17039	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000175691	ZNF77	17.69	94.7795	Q15935	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000196378	ZNF34	15.26	95.5149	Q8IZ26	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000154957	ZNF18	13.57	91.7172	P17022	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000146757	ZNF92	11.79	94.5738	Q03936	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000175395	ZNF25	8.08	93.6634	P17030	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000115966	ATF2	7.58	90.4284	P15336	TF,Epi	ChIP-seq
ENSG00000214293	ENST00000440088	APTR	ENSG00000144161	ZC3H8	7.24	93.28	Q8N5P1	TF,RBP	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000275111	ZNF2	5.13	93.1485	Q9BSG1	TF	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000085274	MYNN	3.73	92.9294	Q9NPC7	TF	NA
ENSG00000214293	ENST00000447009	APTR	ENSG00000167232	ZNF91	62.09	92.199	Q05481	TF	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000214293	ENST00000430801	APTR	ENSG00000137776	SLTM	42.98	90.7719	Q9NWH9	RBP	eCLIP
ENSG00000214293	ENST00000447009	APTR	ENSG00000139746	RBM26	71.39	92.3722	Q5T8P6	RBP	NA
ENSG00000214293	ENST00000447009	APTR	ENSG00000116350	SRSF4	16.05	91.0825	Q08170	RBP	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000130254	SAFB2	74.37	96.537	Q14151	TF,RBP	Predict
ENSG00000214293	ENST00000440088	APTR	ENSG00000004534	RBM6	72.7	95.5421	P78332	RBP	Predict
ENSG00000214293	ENST00000440088	APTR	ENSG00000198000	NOL8	66.78	95.9805	Q76FK4	RBP	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000121057	AKAP1	66.0	92.4882	Q92667	RBP	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000106344	RBM28	64.01	94.7889	Q9NW13	RBP	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000137776	SLTM	63.4	97.1619	Q9NWH9	RBP	eCLIP
ENSG00000214293	ENST00000440088	APTR	ENSG00000139746	RBM26	60.41	93.5326	Q5T8P6	RBP	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000100650	SRSF5	53.48	92.7823	Q13243	RBP	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000148296	SURF6	49.95	91.6144	O75683	RBP	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000100201	DDX17	47.6	94.1959	Q92841	RBP	Predict
ENSG00000214293	ENST00000440088	APTR	ENSG00000124193	SRSF6	42.36	95.3457	Q13247	RBP	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000116560	SFPQ	42.08	90.0314	P23246	RBP,Epi	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000089280	FUS	34.71	92.3051	P35637	RBP	PAR-CLIP
ENSG00000214293	ENST00000440088	APTR	ENSG00000083544	TDRD3	31.3	94.8053	Q9H7E2	RBP,Epi	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000134597	RBMX2	29.53	93.8721	Q9Y388	RBP	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000115875	SRSF7	27.04	90.8208	Q16629	RBP	eCLIP,PAR-CLIP
ENSG00000214293	ENST00000440088	APTR	ENSG00000116350	SRSF4	25.29	95.1999	Q08170	RBP	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000147274	RBMX	22.34	93.2242	P38159	RBP	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000150316	CWC15	18.25	93.47	Q9P013	RBP	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000161547	SRSF2	8.4	92.8567	Q01130	RBP	NA
ENSG00000214293	ENST00000440088	APTR	ENSG00000144161	ZC3H8	7.24	92.8794	Q8N5P1	TF,RBP	NA

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lncRNA-DNA interaction for APTR

lncRNA targets the enhancer region and positively regulates the gene expression.

Only predicted by TDF

ZNF30,RBM39,CIRBP,LCORL,OVOL2,MZF1,HES1,AKAP8,ZNF2,ZXDC,SUGP2,DMTF1,VEZF1,RBM27,ZNF77,RBM28,TBP,GABPA,IKZF5,DDX55,GRHL2,ZFP14,RNPC3,SAFB2,THOC1,ZNF25,LARP7,CNOT4,CHTOP,CWC22,TFAP4,DDX59,ZBED5,CENPT,TTC14,ZNF44,ZNF91,SRSF4,RBMX,RBM4B,CSTF3,RBM26,PURB,ZBTB3,MYEF2,MBD1,CWC15,SURF6,NFYC,DHX34,NFIA,CPSF4,ZFP30,SP4,PPIE,SF3B6,THAP9,ZNF34,THAP6,DDX17,E2F5,PUS7,E2F6,ZNF57,ZNF22,PHF1,SRSF9,ZC3H8,TTF1,HSF4,DZIP3,NIP7,ZFP62,PAIP1,SCMH1,KRR1,TMF1,RTCA,TIGD1,RBM45,NFXL1,MBD4,RBM18,UNC50,SRSF2,MBD6,DDX31,MYNN,TFCP2,ZMAT1,ZNF83,ZNF3,NXF1,ZNF18,GPBP1,C1D,RBM6,HMGN3,ZNF14,KHDC1,RBM48,FOXA1,PLS1,XPO1,RBM5,ELF2,SMAD4,NFYB,ZNF17,ZNF84,DDX42,RXRB,LSM1,TRA2A,ZNF69,SRSF7,AKAP1,XPA,NR2C1,THOC7,ZFP3,SFPQ,NOL8,ATF2,ZNF10

Exist in public source

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for APTR

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

Only predicted by lncTar

AEBP1

Exist in public source

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

lncRNA and exonskipping events positive correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	ORF mutation
ENSG00000214293	ENST00000447009	exon_skip_484062	chr8:73030335-73030395	-13.83	-0.2822	TERF1	ENST00000276603	In-frame
ENSG00000214293	ENST00000447009	exon_skip_423795	chr4:55888887-55888932	-12.28	-0.3149	EXOC1	ENST00000346134,ENST00000381295	In-frame
ENSG00000214293	ENST00000447009	exon_skip_52894	chr10:98431130-98431291	-20.27	-0.1259	HPS1	ENST00000325103,ENST00000361490	Frame-shift

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000214293	ENST00000416650	exon_skip_106783	chr14:55673171-55673255	-7.85	-0.1402	KTN1	ENST00000395314	In-frame
ENSG00000214293	ENST00000447009	exon_skip_111863	chr14:23565815-23565892	-13.46	-0.2103	AP1G2	ENST00000308724,ENST00000397120	Frame-shift
ENSG00000214293	ENST00000447009	exon_skip_319223	chr19:43526200-43526349	-17.57	-0.1689	ETHE1	ENST00000292147	Frame-shift
ENSG00000214293	ENST00000447009	exon_skip_377198	chr3:123130479-123130616	-18.40	-0.1804	PDIA5	ENST00000316218	Frame-shift
ENSG00000214293	ENST00000447009	exon_skip_380242	chr3:186784961-186785101	-14.86	-0.1429	EIF4A2	ENST00000323963	Frame-shift
ENSG00000214293	ENST00000447009	exon_skip_41841	chr10:68756272-68756483	-19.58	-0.1450	CCAR1	ENST00000265872	Frame-shift
ENSG00000214293	ENST00000398043	exon_skip_123601	chr15:74897010-74897219	-14.01	-0.1262	MPI	ENST00000352410	Frame-shift
ENSG00000214293	ENST00000447009	exon_skip_283774	chr17:78171509-78171649	-16.22	-0.1423	SYNGR2	ENST00000225777,ENST00000585591	Frame-shift
ENSG00000214293	ENST00000447009	exon_skip_300663	chr19:1425877-1425960	-11.45	-0.2544	DAZAP1	ENST00000233078	Frame-shift
ENSG00000214293	ENST00000447009	exon_skip_382458	chr3:38131595-38131638	-8.28	-0.2300	ACAA1	ENST00000333167	Frame-shift
ENSG00000214293	ENST00000447009	exon_skip_470226	chr7:103307595-103307708	-12.80	-0.1969	PMPCB	ENST00000249269	Frame-shift
ENSG00000214293	ENST00000447009	exon_skip_494079	chr8:144099080-144099205	-20.60	-0.2575	SHARPIN	ENST00000398712	Frame-shift
ENSG00000214293	ENST00000447009	exon_skip_470719	chr7:117134123-117134192	-8.71	-0.3787	ST7	ENST00000265437	In-frame
ENSG00000214293	ENST00000447009	exon_skip_361434	chr21:25997359-25997416	-10.35	-0.2407	APP	ENST00000346798	In-frame
ENSG00000214293	ENST00000447009	exon_skip_382356	chr3:37091466-37091538	-6.61	-0.1180	LRRFIP2	ENST00000336686	In-frame

lncRNA targets by miRNA.

LncRNA Ensembl ID	miRNA ID	LncRNA ENST ID	Binding site in lncRNA	Score	Energy	Align Len	Public source
ENSG00000214293	hsa-mir-155	ENST00000440088	chr7:77658969-77659033	184.00	-57.60	63	NA
ENSG00000214293	hsa-mir-155	ENST00000440088	chr7:77659438-77659507	170.00	-53.49	64	NA
ENSG00000214293	hsa-mir-155	ENST00000440088	chr7:77658349-77658431	157.00	-56.72	76	NA
ENSG00000214293	hsa-mir-155	ENST00000440088	chr7:77657964-77658029	150.00	-56.11	65	NA
ENSG00000214293	hsa-mir-155	ENST00000440088	chr7:77657678-77657745	145.00	-68.06	61	NA
ENSG00000214293	hsa-mir-155	ENST00000430801	chr7:77659111-77659178	145.00	-68.06	61	NA
ENSG00000214293	hsa-mir-155	ENST00000416650	chr7:77683958-77684025	145.00	-68.06	61	NA
ENSG00000214293	hsa-mir-155	ENST00000416650	chr7:77684168-77684232	145.00	-52.72	63	NA
ENSG00000214293	hsa-mir-155	ENST00000398043	chr7:77684525-77684590	150.00	-56.11	65	NA
ENSG00000214293	hsa-mir-155	ENST00000398043	chr7:77684239-77684306	145.00	-68.06	61	NA
ENSG00000214293	hsa-mir-155	ENST00000447009	chr7:77685077-77685142	150.00	-56.11	65	NA
ENSG00000214293	hsa-mir-155	ENST00000447009	chr7:77684791-77684858	145.00	-68.06	61	NA
ENSG00000214293	hsa-mir-155	ENST00000447009	chr7:77685584-77685653	140.00	-55.48	72	NA
ENSG00000214293	hsa-mir-511	ENST00000440088	chr7:77658265-77658358	207.00	-63.14	89	NA
ENSG00000214293	hsa-mir-511	ENST00000440088	chr7:77658899-77658984	202.00	-59.80	84	NA
ENSG00000214293	hsa-mir-511	ENST00000440088	chr7:77659516-77659601	197.00	-53.41	89	NA
ENSG00000214293	hsa-mir-511	ENST00000440088	chr7:77658747-77658828	185.00	-55.85	85	NA
ENSG00000214293	hsa-mir-511	ENST00000440088	chr7:77657958-77658047	175.00	-67.67	86	NA
ENSG00000214293	hsa-mir-511	ENST00000440088	chr7:77659039-77659129	171.00	-50.70	83	NA
ENSG00000214293	hsa-mir-511	ENST00000440088	chr7:77658658-77658744	158.00	-52.67	84	NA
ENSG00000214293	hsa-mir-511	ENST00000440088	chr7:77659394-77659474	158.00	-63.38	85	NA
ENSG00000214293	hsa-mir-511	ENST00000440088	chr7:77659207-77659291	149.00	-61.80	64	NA
ENSG00000214293	hsa-mir-511	ENST00000440088	chr7:77659304-77659389	149.00	-60.08	86	NA
ENSG00000214293	hsa-mir-511	ENST00000440088	chr7:77658064-77658161	146.00	-59.92	96	NA
ENSG00000214293	hsa-mir-511	ENST00000440088	chr7:77657871-77657965	142.00	-70.40	91	NA
ENSG00000214293	hsa-mir-511	ENST00000440088	chr7:77658444-77658532	142.00	-72.49	88	NA
ENSG00000214293	hsa-mir-511	ENST00000430801	chr7:77659235-77659329	159.00	-61.06	94	NA
ENSG00000214293	hsa-mir-511	ENST00000430801	chr7:77659484-77659581	146.00	-59.92	96	NA
ENSG00000214293	hsa-mir-511	ENST00000416650	chr7:77684454-77684529	164.00	-53.77	83	NA
ENSG00000214293	hsa-mir-511	ENST00000416650	chr7:77684082-77684173	147.00	-59.91	91	NA
ENSG00000214293	hsa-mir-511	ENST00000416650	chr7:77684348-77684450	145.00	-63.68	99	NA
ENSG00000214293	hsa-mir-511	ENST00000416650	chr7:77684145-77684232	144.00	-64.22	63	NA
ENSG00000214293	hsa-mir-511	ENST00000398043	chr7:77684458-77684554	167.00	-66.61	91	NA
ENSG00000214293	hsa-mir-511	ENST00000447009	chr7:77685010-77685106	167.00	-66.61	91	NA
ENSG00000214293	hsa-mir-511	ENST00000447009	chr7:77685498-77685570	161.00	-51.83	85	NA
ENSG00000214293	hsa-mir-511	ENST00000447009	chr7:77685596-77685677	152.00	-54.83	67	NA
ENSG00000214293	hsa-mir-511	ENST00000447009	chr7:77685191-77685279	140.00	-56.15	91	NA
ENSG00000214293	hsa-mir-142	ENST00000440088	chr7:77659530-77659620	189.00	-68.10	87	NA
ENSG00000214293	hsa-mir-142	ENST00000440088	chr7:77658573-77658662	180.00	-86.59	86	NA
ENSG00000214293	hsa-mir-142	ENST00000440088	chr7:77658823-77658918	177.00	-67.48	89	NA
ENSG00000214293	hsa-mir-142	ENST00000440088	chr7:77659386-77659476	172.00	-78.90	75	NA
ENSG00000214293	hsa-mir-142	ENST00000440088	chr7:77659302-77659386	166.00	-70.95	87	NA
ENSG00000214293	hsa-mir-142	ENST00000440088	chr7:77658320-77658401	165.00	-68.04	89	NA
ENSG00000214293	hsa-mir-142	ENST00000440088	chr7:77658911-77659015	164.00	-83.34	100	NA
ENSG00000214293	hsa-mir-142	ENST00000440088	chr7:77659125-77659213	159.00	-75.21	90	NA
ENSG00000214293	hsa-mir-142	ENST00000440088	chr7:77657919-77658005	158.00	-79.11	87	NA
ENSG00000214293	hsa-mir-142	ENST00000440088	chr7:77657661-77657731	153.00	-81.11	72	NA
ENSG00000214293	hsa-mir-142	ENST00000440088	chr7:77657997-77658089	147.00	-74.91	91	NA
ENSG00000214293	hsa-mir-142	ENST00000440088	chr7:77658719-77658802	147.00	-65.94	84	NA
ENSG00000214293	hsa-mir-142	ENST00000440088	chr7:77657827-77657916	144.00	-71.25	91	NA
ENSG00000214293	hsa-mir-142	ENST00000430801	chr7:77659236-77659328	191.00	-72.55	91	NA
ENSG00000214293	hsa-mir-142	ENST00000430801	chr7:77659094-77659164	153.00	-81.11	72	NA
ENSG00000214293	hsa-mir-142	ENST00000416650	chr7:77684041-77684132	164.00	-72.73	90	NA
ENSG00000214293	hsa-mir-142	ENST00000416650	chr7:77684252-77684340	153.00	-77.00	75	NA
ENSG00000214293	hsa-mir-142	ENST00000416650	chr7:77683944-77684011	151.00	-79.92	70	NA
ENSG00000214293	hsa-mir-142	ENST00000398043	chr7:77684598-77684689	164.00	-72.73	90	NA
ENSG00000214293	hsa-mir-142	ENST00000398043	chr7:77684480-77684566	158.00	-79.11	87	NA
ENSG00000214293	hsa-mir-142	ENST00000398043	chr7:77684222-77684292	153.00	-81.11	72	NA
ENSG00000214293	hsa-mir-142	ENST00000398043	chr7:77684388-77684477	144.00	-71.25	91	NA
ENSG00000214293	hsa-mir-142	ENST00000447009	chr7:77685463-77685554	177.00	-74.03	88	NA
ENSG00000214293	hsa-mir-142	ENST00000447009	chr7:77685150-77685241	164.00	-72.73	90	NA
ENSG00000214293	hsa-mir-142	ENST00000447009	chr7:77685273-77685361	161.00	-66.61	89	NA
ENSG00000214293	hsa-mir-142	ENST00000447009	chr7:77685032-77685118	158.00	-79.11	87	NA
ENSG00000214293	hsa-mir-142	ENST00000447009	chr7:77684786-77684844	144.00	-76.06	50	NA
ENSG00000214293	hsa-mir-142	ENST00000447009	chr7:77684940-77685029	144.00	-71.25	91	NA
ENSG00000214293	hsa-mir-3614	ENST00000440088	chr7:77658017-77658115	190.00	-76.37	90	NA
ENSG00000214293	hsa-mir-3614	ENST00000440088	chr7:77658477-77658564	183.00	-76.43	86	NA
ENSG00000214293	hsa-mir-3614	ENST00000440088	chr7:77657689-77657774	172.00	-94.43	86	NA
ENSG00000214293	hsa-mir-3614	ENST00000440088	chr7:77658151-77658234	168.00	-73.26	81	NA
ENSG00000214293	hsa-mir-3614	ENST00000440088	chr7:77659490-77659583	159.00	-60.89	92	NA
ENSG00000214293	hsa-mir-3614	ENST00000440088	chr7:77659124-77659222	158.00	-76.54	94	NA
ENSG00000214293	hsa-mir-3614	ENST00000440088	chr7:77658585-77658669	151.00	-89.23	84	NA
ENSG00000214293	hsa-mir-3614	ENST00000440088	chr7:77658995-77659090	151.00	-63.72	94	NA
ENSG00000214293	hsa-mir-3614	ENST00000440088	chr7:77659574-77659663	151.00	-62.88	85	NA
ENSG00000214293	hsa-mir-3614	ENST00000440088	chr7:77657910-77658001	147.00	-82.35	87	NA
ENSG00000214293	hsa-mir-3614	ENST00000440088	chr7:77658863-77658953	147.00	-64.03	89	NA
ENSG00000214293	hsa-mir-3614	ENST00000440088	chr7:77658340-77658423	146.00	-69.42	83	NA
ENSG00000214293	hsa-mir-3614	ENST00000440088	chr7:77659231-77659317	146.00	-73.37	82	NA
ENSG00000214293	hsa-mir-3614	ENST00000430801	chr7:77659439-77659535	189.00	-75.64	96	NA
ENSG00000214293	hsa-mir-3614	ENST00000430801	chr7:77659571-77659654	168.00	-73.26	81	NA
ENSG00000214293	hsa-mir-3614	ENST00000430801	chr7:77659334-77659439	166.00	-93.27	101	NA
ENSG00000214293	hsa-mir-3614	ENST00000430801	chr7:77659231-77659318	161.00	-74.60	89	NA
ENSG00000214293	hsa-mir-3614	ENST00000430801	chr7:77659094-77659177	159.00	-88.19	89	NA
ENSG00000214293	hsa-mir-3614	ENST00000416650	chr7:77684229-77684314	214.00	-79.39	86	NA
ENSG00000214293	hsa-mir-3614	ENST00000416650	chr7:77684415-77684493	178.00	-71.02	83	NA
ENSG00000214293	hsa-mir-3614	ENST00000416650	chr7:77684322-77684407	176.00	-71.31	85	NA
ENSG00000214293	hsa-mir-3614	ENST00000416650	chr7:77684144-77684216	168.00	-74.30	78	NA
ENSG00000214293	hsa-mir-3614	ENST00000416650	chr7:77684015-77684091	160.00	-80.58	80	NA
ENSG00000214293	hsa-mir-3614	ENST00000416650	chr7:77683944-77684024	157.00	-87.90	87	NA
ENSG00000214293	hsa-mir-3614	ENST00000398043	chr7:77684557-77684648	206.00	-84.19	93	NA
ENSG00000214293	hsa-mir-3614	ENST00000398043	chr7:77684250-77684335	172.00	-94.43	86	NA
ENSG00000214293	hsa-mir-3614	ENST00000398043	chr7:77684471-77684562	147.00	-82.35	87	NA
ENSG00000214293	hsa-mir-3614	ENST00000447009	chr7:77685109-77685200	206.00	-84.19	93	NA
ENSG00000214293	hsa-mir-3614	ENST00000447009	chr7:77685424-77685498	184.00	-66.33	86	NA
ENSG00000214293	hsa-mir-3614	ENST00000447009	chr7:77684802-77684887	172.00	-94.43	86	NA
ENSG00000214293	hsa-mir-3614	ENST00000447009	chr7:77685512-77685602	162.00	-70.78	90	NA
ENSG00000214293	hsa-mir-3614	ENST00000447009	chr7:77685023-77685114	147.00	-82.35	87	NA
ENSG00000214293	hsa-mir-3614	ENST00000447009	chr7:77685253-77685340	140.00	-62.88	83	NA

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Variants for APTR

RNA A-to-I editing events in lncRNA.

LncRNAediting ID	LncRNA Ensembl ID	Chromosome	Editing Position	Strand	Gene Type	Gene Name	Transcript ID	Transcript Type	Transcript Name
LncEditing_187250	ENSG00000214293.7	chr7	77658846	-	lincRNA	APTR	ENST00000440088.4	lincRNA	APTR-001
LncEditing_187492	ENSG00000214293.7	chr7	77675170	-	lincRNA	APTR	ENST00000440088.4	lincRNA	APTR-001
LncEditing_187878	ENSG00000214293.7	chr7	77683341	-	lincRNA	APTR	ENST00000440088.4	lincRNA	APTR-001

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID	LncRNA Index	Cancer Type	Chr_Postion_Strand	AVE1	AVE2	log2FC	W-value	P-value	Adjc.p-value	Change
ENSG00000214293	LncEditing_187250	GBM	chr7_77658846_-	5.611097e+00	4.409042e+00	2.875070e+00	3.725490e+00	1.949360e-04	2.615311e-04	UP
ENSG00000214293	LncEditing_187492	ESCA	chr7_77675170_-	4.039054e+00	2.209003e+00	1.148604e+00	5.721873e+00	1.053559e-08	2.271873e-08	UP
ENSG00000214293	LncEditing_187878	ESCA	chr7_77683341_-	4.421806e+00	2.292404e+00	1.055103e+00	4.620194e+00	3.833809e-06	5.719334e-06	UP

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID

LncRNA ENST ID

PC Gene Name

PC Gene ID

PC ENST ID

nDG

Cancer with PC gene up-regulation

Cancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID	lncRNA-miRNA-mRNA	Cancer Types
ENSG00000214293	APTR,hsa-mir-155,BEX4	PCPG,THCA,UVM,PAAD,THYM
ENSG00000214293	APTR,hsa-mir-511,NR2C2	PCPG,CHOL,UCS,SARC,KIRP
ENSG00000214293	APTR,hsa-mir-511,DMTF1	PCPG,CHOL,UCS,SARC,KIRP
ENSG00000214293	APTR,hsa-mir-511,N4BP2L2	PCPG,CHOL,UCS,SARC,KIRP
ENSG00000214293	APTR,hsa-mir-511,SPIN3	PCPG,CHOL,UCS,SARC,KIRP
ENSG00000214293	APTR,hsa-mir-511,SLC2A11	PCPG,CHOL,PAAD,SARC,KIRP
ENSG00000214293	APTR,hsa-mir-511,BEX2	PCPG,CHOL,THCA,PAAD,SARC
ENSG00000214293	APTR,hsa-mir-511,MORN4	PCPG,CHOL,THCA,UCS,KIRP
ENSG00000214293	APTR,hsa-mir-511,DTX3	PCPG,CHOL,THCA,PAAD,KIRP
ENSG00000214293	APTR,hsa-mir-511,C20orf96	PCPG,CHOL,THCA,UCS,PAAD,SARC,KIRP
ENSG00000214293	APTR,hsa-mir-511,CBFA2T2	PCPG,CHOL,THCA,PAAD,SARC
ENSG00000214293	APTR,hsa-mir-511,FLVCR1	PCPG,CHOL,UCS,PAAD,SARC
ENSG00000214293	APTR,hsa-mir-511,GGT7	PCPG,CHOL,THCA,UCS,SARC
ENSG00000214293	APTR,hsa-mir-511,UBN2	PCPG,CHOL,UCS,SARC,KIRP
ENSG00000214293	APTR,hsa-mir-511,C12orf73	CHOL,THCA,UCS,PAAD,KIRP
ENSG00000214293	APTR,hsa-mir-511,PNMA8A	CHOL,THCA,UCS,PAAD,SARC,KIRP
ENSG00000214293	APTR,hsa-mir-511,C17orf75	CHOL,THCA,PAAD,SARC,KIRP
ENSG00000214293	APTR,hsa-mir-511,GKAP1	PCPG,THCA,PAAD,SARC,KIRP
ENSG00000214293	APTR,hsa-mir-511,ZC3H8	PCPG,CHOL,THCA,UCS,KIRP
ENSG00000214293	APTR,hsa-mir-511,SH2B1	PCPG,CHOL,THCA,UCS,SARC,KIRP
ENSG00000214293	APTR,hsa-mir-511,MYEF2	PCPG,CHOL,UCS,SARC,KIRP
ENSG00000214293	APTR,hsa-mir-511,OGA	PCPG,CHOL,UCS,SARC,KIRP
ENSG00000214293	APTR,hsa-mir-511,COA5	CHOL,THCA,UCS,SARC,KIRP
ENSG00000214293	APTR,hsa-mir-511,TSC2	PCPG,CHOL,THCA,UCS,SARC,KIRP
ENSG00000214293	APTR,hsa-mir-511,C14orf93	CHOL,THCA,UCS,PAAD,SARC,KIRP
ENSG00000214293	APTR,hsa-mir-511,GAS8	PCPG,CHOL,THCA,PAAD,SARC,KIRP
ENSG00000214293	APTR,hsa-mir-511,ZFP41	CHOL,THCA,PAAD,SARC,KIRP
ENSG00000214293	APTR,hsa-mir-511,IFT172	PCPG,CHOL,THCA,UCS,KIRP
ENSG00000214293	APTR,hsa-mir-511,BRSK1	PCPG,CHOL,PAAD,SARC,KIRP
ENSG00000214293	APTR,hsa-mir-142,TOM1L2	CHOL,THCA,PAAD,SARC,THYM
ENSG00000214293	APTR,hsa-mir-142,MANBAL	KICH,CHOL,PAAD,SARC,THYM
ENSG00000214293	APTR,hsa-mir-142,FBXL2	KICH,THCA,PAAD,SARC,THYM
ENSG00000214293	APTR,hsa-mir-142,NRSN2	CHOL,THCA,PAAD,SARC,THYM
ENSG00000214293	APTR,hsa-mir-142,TMED4	CHOL,THCA,PAAD,SARC,THYM
ENSG00000214293	APTR,hsa-mir-142,DMTN	KICH,CHOL,PAAD,SARC,THYM

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000214293.7	ENST00000440088.4	137	21	434
ENSG00000214293.7	ENST00000430801.4	96	431	721
ENSG00000214293.7	ENST00000416650.4	71	107	322
ENSG00000214293.7	ENST00000398043.2	118	565	209
ENSG00000214293.7	ENST00000447009.1	69	206	0

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential