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lncRNA: ENSG00000205559

Summary for CHKB-DT

Gene summary

Gene information	Ensembl ID	ENSG00000205559
	Gene symbol	CHKB-DT
	Gene name	CHKB divergent transcript
	HGNC	40146
	Entrez ID	100144603
	Gene type	antisense
	Synonyms	CHKB-DT\|CHKB-AS1\|22q13.33
	UniProtAcc

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Structure and expression level for CHKB-DT

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000205559	5.528019e+01	1.191553e+00	1.670188e-01	7.134247e+00	9.730000e-13	7.640000e-12	UP	KICH
ENSG00000205559	4.254103e+01	1.524025e+00	2.375404e-01	6.415854e+00	1.400000e-10	2.870000e-09	UP	BLCA
ENSG00000205559	3.297392e+01	2.025815e+00	2.078433e-01	9.746835e+00	1.900000e-22	3.690000e-21	UP	UCEC
ENSG00000205559	6.485126e+01	1.200840e+00	2.852220e-01	4.210194e+00	2.550000e-05	4.190360e-04	UP	ESCA
ENSG00000205559	5.624391e+01	1.500155e+00	1.339955e-01	1.119557e+01	4.290000e-29	4.400000e-28	UP	LUSC
ENSG00000205559	4.756637e+01	1.061047e+00	9.551537e-02	1.110865e+01	1.140000e-28	1.090000e-27	UP	BRCA
ENSG00000205559	3.337136e+01	1.041760e+00	1.346906e-01	7.734462e+00	1.040000e-14	7.130000e-14	UP	LUAD
ENSG00000205559	2.384039e+01	1.091312e+00	3.312710e-01	3.294319e+00	9.866040e-04	5.535922e-03	UP	READ

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000205559	4.611358e-01	5.419685e-06	KICH	1.230497e-05
ENSG00000205559	3.136745e-01	1.394357e-10	LIHC	5.091237e-10
ENSG00000205559	3.205081e-01	1.724901e-15	UCEC	1.986250e-14

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lncRNA-Protein interaction for CHKB-DT

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

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lncRNA-DNA interaction for CHKB-DT

lncRNA targets the enhancer region and positively regulates the gene expression.

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for CHKB-DT

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

Only predicted by lncTar

CNOT1,PLEKHG1,NF1,DSTYK,FAM168B,KPNB1,SLC35E1,RBBP4,QKI,APPL2,ARID1A,ITSN1,MSI2,MARCHF6,UHRF1BP1L,RNF123,RBBP6,AIDA,NT5C2,ZMYND11,ATM,BECN1,REV1,MAP4K3,FRS2,HIPK1,QRICH1,SMCR8,SNX6,UBR1,TRAPPC10,PPP1R12A,SEPTIN10,CHD8,DHX40,LRBA,UBXN7,TAOK3,INTS6,RC3H1,TRIP11,RIOK3,KIAA1109,SCYL2,KAT6B,PRDM2,BZW1,HECTD1,CUL4A,FCHO2,CREBBP,POLR2A,PBX1,SLAIN2,RAB5A,PKN2,ANKFY1,ERBIN,DNAJC14,PBRM1,PHACTR2,ARIH1,ZSWIM8,HEATR6,KANSL1L,PUM1,SEC24B,MAN1A2,ZC3H11A,ATF7,PARG,ATP2A2,WASF2,NAPEPLD,SON,SH3GLB1,PIK3C3,MACF1,ATP11B,NBR1,VGLL4,PRRC2C,KMT2D,SPRED2,PDPK1,KTN1,PKD2,C5orf24,ACBD5,ARFIP1,USP33,CEP120,APAF1,GBF1,FBXO21,BBX,SNX29,TAF1,ARID1B,PTPN21,TP53BP1,WDR48,GPR107,UBR4,DDI2,DENND2B,USP32,SH3BP5,SNRK,KIDINS220,IQGAP1,DYNC1I2,ZDHHC17,ACOX1,SMARCA2,SLMAP,CLIP1,SESTD1,ARNT,PIAS1,APPBP2,FBXO11,DDX6,BPTF,ATF2,STK24,PTPRB,RC3H2,BCLAF1,ARHGAP5,DDX3X,RSRC2,ITSN2,MPDZ,RNF38,ASXL2,ZMIZ1,NIPBL,LSM14A,SLTM,FTO,MTMR10,SMAD1,FRYL,WIPF2,TBC1D2B,BAZ2A,TRIM56,CEP350,SF3B1,PIKFYVE,SNRNP200,MIER3,ADD1,USP9X,ZFAND3,ARSB,ROCK2,ACVR1,RHBDD1,ZFYVE1,UBE4B,PCM1,MED12,SEPTIN8,ASH1L,VEZT,NDST1,DYNC1LI2,BRPF3,SLC10A7,POC1B,MIDEAS,YAP1,RASA1,TNS1,APP,ZNF106,SAMD8,CERT1,WNK1,PUM2,VPS52,SSH1,MARCHF7,OSBPL8,XRN1,NFKB1,MBNL2,SMG6,MED13L,SEPTIN2,KIAA0232,COG6,MTRR,EPS15,KIAA0586,LYSMD3,GAB1,GOLGA2,ARHGEF18,ACTR2,DCAF7,DOCK9,SYNJ1,PLSCR4,TRIP12,GPATCH8,CNOT8,PDCD6IP,CHD2,GTF2A1,RABGAP1,CHD9,NEO1,TNPO1,MPHOSPH8,MED1,PPIG,SOS1,REST,SMAD5,PLS1,CNST,PPFIBP1,MORC3,STX7,HBP1,NEK7,SOS2,SPTLC1,THRAP3,FAM160B1,CLASP1,TUBGCP3,GOSR1,HEATR5B,POLK,PRKAR1A,PPP3CB,SEC31A,CTNNA1,IL6ST,RB1,ZZEF1,VRK2,KMT2E,GCC2,LPP,NSRP1,DCAF5,CHD6,RSPH3,USP8,SECISBP2L,TLK1,BDP1,DHX57,TRIM33,SYNRG,ABHD16A,MED23,PHF2,NOTCH2,SLC30A7,TPP2,PAFAH1B1,SEC24C,MIA3,SPG11,DLG1,CCNK,LATS1,CTDSP2,EPC1,AHNAK,AFAP1,FYCO1,DOCK1,IBTK,MPHOSPH10,SPOPL,AFDN,NDUFS1,FNBP1L,NCOR1,SCAF11

Exist in public source

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

LncRNA Ensembl ID

LncRNA ENST ID

Exon ID

Skipped Exon

ndG

Gene name with skipped exon

TransID with skipped exon

ORF mutation

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000205559	ENST00000380711	exon_skip_59439	chr11:57737912-57738026	-12.99	-0.1286	TMX2	ENST00000278422	In-frame

lncRNA targets by miRNA.

LncRNA Ensembl ID

miRNA ID

LncRNA ENST ID

Binding site in lncRNA

Score

Energy

Align Len

Public source

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Variants for CHKB-DT

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID	LncRNA ENST ID	PC Gene Name	PC Gene ID	PC ENST ID	dG	nDG	Cancer with PC gene up-regulation	Cancer with PC gene Down-regulation
ENSG00000205559	ENST00000380711	PTPN21	ENSG00000070778	ENST00000553531	-0.1089	46	-	BLCA,UCEC,ESCA,LUSC,BRCA,LUAD,READ
ENSG00000205559	ENST00000380711	PTPN21	ENSG00000070778	ENST00000536337	-0.1280	1	-	BLCA,UCEC,ESCA,LUSC,BRCA,LUAD,READ
ENSG00000205559	ENST00000380711	ZZEF1	ENSG00000074755	ENST00000381638	-0.1131	1	-	READ
ENSG00000205559	ENST00000380711	ZZEF1	ENSG00000074755	ENST00000573183	-0.1372	1	-	READ
ENSG00000205559	ENST00000380711	ZZEF1	ENSG00000074755	ENST00000572699	-0.1100	9	-	READ
ENSG00000205559	ENST00000380711	TNS1	ENSG00000079308	ENST00000453356	-0.1501	30	-	BLCA,UCEC,ESCA,LUSC,BRCA,LUAD,READ
ENSG00000205559	ENST00000380711	ARHGEF18	ENSG00000104880	ENST00000319670	-0.1015	1	-	READ
ENSG00000205559	ENST00000380711	ARHGEF18	ENSG00000104880	ENST00000359920	-0.1015	1	-	READ
ENSG00000205559	ENST00000380711	ARHGEF18	ENSG00000104880	ENST00000594665	-0.1015	1	-	READ
ENSG00000205559	ENST00000380711	PPP1R12A	ENSG00000058272	ENST00000550299	-0.1697	66	-	BLCA,UCEC,READ
ENSG00000205559	ENST00000380711	NEO1	ENSG00000067141	ENST00000560262	-0.3200	7	-	READ
ENSG00000205559	ENST00000380711	NEO1	ENSG00000067141	ENST00000558964	-0.3200	7	-	READ
ENSG00000205559	ENST00000380711	RIOK3	ENSG00000101782	ENST00000577501	-0.1169	105	-	READ
ENSG00000205559	ENST00000380711	RIOK3	ENSG00000101782	ENST00000584130	-0.1085	22	-	READ
ENSG00000205559	ENST00000380711	DHX40	ENSG00000108406	ENST00000425628	-0.1324	139	-	KICH
ENSG00000205559	ENST00000380711	ARSB	ENSG00000113273	ENST00000565165	-0.1685	5	-	KICH
ENSG00000205559	ENST00000380711	PLEKHG1	ENSG00000120278	ENST00000475490	-0.1241	1	-	KICH
ENSG00000205559	ENST00000380711	KIAA1109	ENSG00000138688	ENST00000419325	-0.2136	521	-	LUSC
ENSG00000205559	ENST00000380711	KIAA1109	ENSG00000138688	ENST00000442707	-0.5280	25	-	LUSC
ENSG00000205559	ENST00000380711	MIER3	ENSG00000155545	ENST00000451637	-0.2102	61	-	READ
ENSG00000205559	ENST00000380711	FCHO2	ENSG00000157107	ENST00000287761	-0.2034	104	-	LUSC,READ
ENSG00000205559	ENST00000380711	CERT1	ENSG00000113163	ENST00000261415	-0.1997	334	-	LUSC
ENSG00000205559	ENST00000380711	CERT1	ENSG00000113163	ENST00000508809	-0.1015	317	-	LUSC
ENSG00000205559	ENST00000380711	SH3BP5	ENSG00000131370	ENST00000450625	-0.1096	24	-	KICH,UCEC,ESCA,LUSC,LUAD
ENSG00000205559	ENST00000380711	NAPEPLD	ENSG00000161048	ENST00000420631	-0.1013	38	-	KICH
ENSG00000205559	ENST00000380711	FYCO1	ENSG00000163820	ENST00000438446	-0.1301	53	-	BLCA,UCEC,ESCA,LUSC,READ
ENSG00000205559	ENST00000380711	SEPTIN2	ENSG00000168385	ENST00000457335	-0.1464	1	-	KICH
ENSG00000205559	ENST00000380711	PLS1	ENSG00000120756	ENST00000497002	-0.1433	50	-	KICH,READ
ENSG00000205559	ENST00000380711	AHNAK	ENSG00000124942	ENST00000530124	-0.1397	1	-	BLCA,UCEC,LUSC,BRCA,LUAD,READ
ENSG00000205559	ENST00000380711	AHNAK	ENSG00000124942	ENST00000257247	-0.1191	1	-	BLCA,UCEC,LUSC,BRCA,LUAD,READ
ENSG00000205559	ENST00000380711	NOTCH2	ENSG00000134250	ENST00000579475	-0.1184	300	-	KICH
ENSG00000205559	ENST00000380711	LPP	ENSG00000145012	ENST00000415906	-0.1148	95	-	BLCA,UCEC,ESCA,READ
ENSG00000205559	ENST00000380711	IL6ST	ENSG00000134352	ENST00000502326	-0.1871	4	-	BLCA,UCEC,ESCA,LUSC,READ
ENSG00000205559	ENST00000380711	GAB1	ENSG00000109458	ENST00000512843	-0.1085	19	-	UCEC,LUSC,LUAD,READ
ENSG00000205559	ENST00000380711	PPFIBP1	ENSG00000110841	ENST00000535047	-0.1229	442	-	KICH,LUAD
ENSG00000205559	ENST00000380711	PLSCR4	ENSG00000114698	ENST00000493382	-0.2786	14	-	KICH,BLCA,UCEC,LUSC,BRCA,LUAD,READ
ENSG00000205559	ENST00000380711	CNST	ENSG00000162852	ENST00000366511	-0.2119	21	-	BLCA,READ
ENSG00000205559	ENST00000380711	AFAP1	ENSG00000196526	ENST00000382543	-0.2152	1	-	KICH,BLCA
ENSG00000205559	ENST00000380711	AFAP1	ENSG00000196526	ENST00000614385	-0.1045	355	-	KICH,BLCA
ENSG00000205559	ENST00000380711	SLMAP	ENSG00000163681	ENST00000416658	-0.1060	1	-	BLCA,UCEC,READ
ENSG00000205559	ENST00000380711	SLMAP	ENSG00000163681	ENST00000417128	-0.1060	1	-	BLCA,UCEC,READ
ENSG00000205559	ENST00000380711	SLMAP	ENSG00000163681	ENST00000495364	-0.1934	184	-	BLCA,UCEC,READ
ENSG00000205559	ENST00000380711	SLMAP	ENSG00000163681	ENST00000494088	-0.1203	42	-	BLCA,UCEC,READ
ENSG00000205559	ENST00000380711	SLMAP	ENSG00000163681	ENST00000460223	-0.1060	1	-	BLCA,UCEC,READ
ENSG00000205559	ENST00000380711	PKD2	ENSG00000118762	ENST00000508588	-0.1124	14	-	KICH,BLCA,UCEC,BRCA,READ
ENSG00000205559	ENST00000380711	PKD2	ENSG00000118762	ENST00000502363	-0.4200	569	-	KICH,BLCA,UCEC,BRCA,READ
ENSG00000205559	ENST00000380711	YAP1	ENSG00000137693	ENST00000531439	-0.5367	277	-	UCEC,BRCA
ENSG00000205559	ENST00000380711	YAP1	ENSG00000137693	ENST00000524575	-0.1134	17	-	UCEC,BRCA
ENSG00000205559	ENST00000380711	SNRK	ENSG00000163788	ENST00000437827	-0.1329	131	-	BLCA,UCEC,LUSC,LUAD,READ
ENSG00000205559	ENST00000380711	SOS2	ENSG00000100485	ENST00000543680	-0.3708	478	-	READ
ENSG00000205559	ENST00000380711	SOS2	ENSG00000100485	ENST00000556452	-0.1793	104	-	READ
ENSG00000205559	ENST00000380711	ZNF106	ENSG00000103994	ENST00000569648	-0.1994	109	-	BLCA,LUSC,BRCA,LUAD
ENSG00000205559	ENST00000380711	PTPRB	ENSG00000127329	ENST00000538708	-0.1765	75	-	KICH,UCEC,ESCA,LUSC,BRCA,LUAD
ENSG00000205559	ENST00000380711	PTPRB	ENSG00000127329	ENST00000550857	-0.1765	75	-	KICH,UCEC,ESCA,LUSC,BRCA,LUAD
ENSG00000205559	ENST00000380711	PTPRB	ENSG00000127329	ENST00000261266	-0.1765	75	-	KICH,UCEC,ESCA,LUSC,BRCA,LUAD
ENSG00000205559	ENST00000380711	SECISBP2L	ENSG00000138593	ENST00000561428	-0.1349	155	-	ESCA,LUSC,LUAD,READ
ENSG00000205559	ENST00000380711	DOCK1	ENSG00000150760	ENST00000623213	-0.3206	177	-	KICH
ENSG00000205559	ENST00000380711	MTMR10	ENSG00000166912	ENST00000566981	-0.1146	296	-	LUSC,BRCA,LUAD,READ

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID

lncRNA ENST ID

length(AA)

start at transcript

end at transcript

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential