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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000203499

Summary for FAM83H-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000203499

Gene symbol

FAM83H-AS1

Gene name
HGNC
Entrez ID

642574

Gene typelincRNA
Synonyms
UniProtAcc

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Structure and expression level for FAM83H-AS1

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002034996.887532e+024.803714e+004.800461e-011.000677e+011.420000e-231.170000e-21UPCHOL
ENSG000002034998.904699e+022.245424e+005.535449e-014.056444e+004.980000e-059.984918e-03UPPAAD
ENSG000002034992.763091e+031.232318e+002.861482e-014.306571e+001.660000e-051.084280e-04UPBLCA
ENSG000002034992.810446e+035.682798e+005.589756e-011.016645e+012.800000e-246.850000e-22UPCESC
ENSG000002034999.004257e+022.265435e+001.755497e-011.290481e+014.230000e-382.320000e-36UPUCEC
ENSG000002034992.292151e+031.345111e+001.170536e-011.149141e+011.460000e-301.340000e-28UPPRAD
ENSG000002034993.376002e+033.010050e+001.270239e-012.369672e+013.900000e-1246.750000e-122UPLUSC
ENSG000002034993.232472e+032.226261e+009.453538e-022.354950e+011.270000e-1221.960000e-120UPBRCA
ENSG000002034991.752868e+032.268440e+001.248891e-011.816364e+011.000000e-731.560000e-71UPLUAD
ENSG000002034991.186327e+032.846645e+001.320419e-012.155865e+014.390000e-1033.730000e-100UPCOAD
ENSG000002034992.493899e+031.279721e+002.157793e-015.930693e+003.020000e-093.270000e-08UPSTAD
ENSG000002034991.319589e+032.949016e+002.645270e-011.114826e+017.300000e-295.830000e-26UPREAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002034995.356446e-011.495923e-04CHOL4.111344e-04
ENSG00000203499-4.811760e-011.813245e-06KICH4.776064e-06
ENSG000002034993.090174e-011.969090e-14LUAD2.382932e-13
ENSG000002034993.121912e-017.874565e-14LUSC2.260656e-12
ENSG000002034993.929833e-018.611763e-22PRAD3.523646e-20
ENSG000002034993.282777e-013.243481e-16UCEC4.324641e-15

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lncRNA-Protein interaction for FAM83H-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000203499ENST00000533004FAM83H-AS1ENSG00000187605TET359.5692.6152O43151TF,EpiNA
ENSG00000203499ENST00000533004FAM83H-AS1ENSG00000140632GLYR121.5391.1741Q49A26TF,EpiNA
ENSG00000203499ENST00000533004FAM83H-AS1ENSG00000123636BAZ2B91.795.5949Q9UIF8TF,EpiNA
ENSG00000203499ENST00000534398FAM83H-AS1ENSG00000104517UBR525.3591.0614O95071RBP,EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000203499ENST00000533004FAM83H-AS1ENSG00000123636BAZ2B91.795.5655Q9UIF8TF,EpiNA
ENSG00000203499ENST00000533004FAM83H-AS1ENSG00000187605TET359.5692.6671O43151TF,EpiNA
ENSG00000203499ENST00000533004FAM83H-AS1ENSG00000105127AKAP857.0692.4712O43823TFNA
ENSG00000203499ENST00000533004FAM83H-AS1ENSG00000126464PRR1242.6592.3789Q9ULL5TFNA
ENSG00000203499ENST00000533004FAM83H-AS1ENSG00000170631ZNF1639.3190.1257P17020TFNA
ENSG00000203499ENST00000533004FAM83H-AS1ENSG00000196670ZFP6237.7692.2244Q8NB50TFNA
ENSG00000203499ENST00000533004FAM83H-AS1ENSG00000147789ZNF736.092.0599P17097TFNA
ENSG00000203499ENST00000533004FAM83H-AS1ENSG00000140632GLYR121.5391.2727Q49A26TF,EpiNA
ENSG00000203499ENST00000533004FAM83H-AS1ENSG00000196378ZNF3415.4192.6726Q8IZ26TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000203499ENST00000533004FAM83H-AS1ENSG00000122965RBM1972.8294.0284Q9Y4C8RBPNA
ENSG00000203499ENST00000533004FAM83H-AS1ENSG00000121057AKAP159.5991.1829Q92667RBPNA
ENSG00000203499ENST00000533004FAM83H-AS1ENSG00000085872CHERP44.1790.3306Q8IWX8RBPNA
ENSG00000203499ENST00000533004FAM83H-AS1ENSG00000135870RC3H141.6191.3615Q5TC82RBPNA
ENSG00000203499ENST00000533004FAM83H-AS1ENSG00000167978SRRM219.3497.6346Q9UQ35RBPNA
ENSG00000203499ENST00000533004FAM83H-AS1ENSG00000254726MEX3A16.6590.5588A1L020RBPNA

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lncRNA-DNA interaction for FAM83H-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
PUS7,HSF1,RBM19,TFAP4,PRR12,LCOR,SRSF9,KLF3,MYC,ZNF16,TBX6,CPSF3,NOP2,ILF3,ZC3H8,GLI4,NOL6,PA2G4,NOL3,GLYR1,PUM2,XPO1,TEAD3,FOXM1,OTX1,RC3H1,NIP7,PUF60,MEX3A,TIGD5,OVOL2,ZFP62,PARN,AKAP8,SRCAP,WIZ,IRX3,CPSF2,AGO2,DDX42,U2AF2,BAZ2B,CPSF1,NFXL1,ZHX2,RBM14,ADNP,HELZ2,HOMEZ,DHX34,RBM28,ZNF74,APEX1,ATF6B,AKAP1,HINFP,MBD6,SP6,ZBED4,DDX55,GRHL2,RARG,SIM2,TET3,UBR5,ZNF34,IRF6,KDM5B,PATZ1,E2F5,SRRM2
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.
Only predicted by TDF
E2F5,UBR5,NOL3,AGO2,IRF6,U2AF2,DKC1,TFAP4,TERF1,HOMEZ,CPSF2,FOXK2,DDX10,AKAP1
Exist in public source
NA

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for FAM83H-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
ZEB2,JAZF1,CELF2,LYL1,SPI1
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000203499ENST00000534398exon_skip_2091chr1:17634547-17634562-8.56-0.7782ARHGEF10LENST00000361221In-frame
ENSG00000203499ENST00000534398exon_skip_11286chr1:155061903-155061975-16.29-0.2431ADAM15ENST00000356955In-frame
ENSG00000203499ENST00000534398exon_skip_14329chr1:178892229-178892307-12.76-0.1724RALGPS2ENST00000367635In-frame
ENSG00000203499ENST00000534398exon_skip_44853chr10:104010815-104010908-11.63-0.2373SLKENST00000369755In-frame
ENSG00000203499ENST00000534398exon_skip_64604chr11:102209516-102209564-10.43-0.2819YAP1ENST00000282441In-frame
ENSG00000203499ENST00000534398exon_skip_64939chr11:112230207-112230230-5.37-0.2557PTSENST00000280362Frame-shift
ENSG00000203499ENST00000534398exon_skip_98384chr12:124327408-124327633-35.94-0.1634NCOR2ENST00000405201In-frame
ENSG00000203499ENST00000534398exon_skip_114200chr14:73279280-73279424-19.48-0.1510NUMBENST00000355058,ENST00000555238In-frame
ENSG00000203499ENST00000534398exon_skip_126350chr15:42192065-42192098-11.09-0.4107VPS39ENST00000348544In-frame
ENSG00000203499ENST00000534398exon_skip_131398chr15:101286213-101286293-13.11-0.1681SNRPA1ENST00000254193Frame-shift
ENSG00000203499ENST00000534398exon_skip_132443chr16:2077597-2077726-17.51-0.2538TSC2ENST00000219476In-frame
ENSG00000203499ENST00000534398exon_skip_148110chr17:4892401-4892512-22.41-0.2094MINK1ENST00000355280In-frame
ENSG00000203499ENST00000534398exon_skip_289780chr17:41896619-41896649-9.08-0.4324ACLYENST00000352035,ENST00000590151In-frame
ENSG00000203499ENST00000534398exon_skip_303809chr19:18431352-18431418-17.39-0.2947SSBP4ENST00000270061In-frame
ENSG00000203499ENST00000534398exon_skip_378912chr3:152446703-152446757-11.13-0.2782MBNL1ENST00000282486,ENST00000463374In-frame
ENSG00000203499ENST00000534398exon_skip_384879chr3:52554723-52554879-26.01-0.1885PBRM1ENST00000296302In-frame
ENSG00000203499ENST00000534398exon_skip_386291chr3:108050577-108050602-6.60-0.4125CD47ENST00000361309Frame-shift
ENSG00000203499ENST00000534398exon_skip_423795chr4:55888887-55888932-9.66-0.3116EXOC1ENST00000346134,ENST00000381295In-frame
ENSG00000203499ENST00000534398exon_skip_461111chr6:90544551-90544632-12.71-0.2154MAP3K7ENST00000369329In-frame
ENSG00000203499ENST00000534398exon_skip_482403chr8:27445793-27445919-15.87-0.1417PTK2BENST00000346049,ENST00000397501In-frame
ENSG00000203499ENST00000534398exon_skip_499771chr9:128592982-128593042-11.38-0.2188SPTAN1ENST00000372731In-frame
ENSG00000203499ENST00000534398exon_skip_517627chrX:154357250-154357274-8.47-0.6515FLNAENST00000369850In-frame
ENSG00000203499ENST00000534398exon_skip_13507chr1:162592731-162592782-8.53-0.7755UAP1ENST00000271469,ENST00000367925In-frame
ENSG00000203499ENST00000534398exon_skip_516535chrX:119840645-119840684-6.52-0.2037UPF3BENST00000276201In-frame
ENSG00000203499ENST00000534398exon_skip_325891chr2:62987930-62988038-12.26-0.1251EHBP1ENST00000263991In-frame
ENSG00000203499ENST00000534398exon_skip_326009chr2:64581189-64581273-16.41-0.2001AFTPHENST00000238855,ENST00000409933In-frame
ENSG00000203499ENST00000534398exon_skip_434332chr5:34813573-34813660-10.11-0.1330RAI14ENST00000265109,ENST00000428746,ENST00000503673In-frame
ENSG00000203499ENST00000534398exon_skip_5133chr1:43602070-43602097-8.64-0.3927PTPRFENST00000359947In-frame
ENSG00000203499ENST00000534398exon_skip_507736chr9:129915965-129915980-4.51-0.6443FNBP1ENST00000446176In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000203499ENST00000534398exon_skip_33516chr1:156938417-156938513-20.56-0.2477ARHGEF11ENST00000361409In-frame
ENSG00000203499ENST00000534398exon_skip_48327chr10:26771074-26771089-6.13-0.5573ABI1ENST00000376142In-frame
ENSG00000203499ENST00000534398exon_skip_62282chr11:68050486-68050664-29.49-0.2048TCIRG1ENST00000265686Frame-shift
ENSG00000203499ENST00000534398exon_skip_90104chr12:10709907-10710114-25.61-0.1362YBX3ENST00000228251In-frame
ENSG00000203499ENST00000534398exon_skip_293641chr17:76091142-76091235-12.67-0.1440EXOC7ENST00000589210In-frame
ENSG00000203499ENST00000534398exon_skip_357772chr20:47659398-47659452-9.74-0.2319SULF2ENST00000359930,ENST00000484875In-frame
ENSG00000203499ENST00000534398exon_skip_368285chr22:29329711-29329720-2.82-0.5640AP1B1ENST00000357586,ENST00000405198In-frame
ENSG00000203499ENST00000534398exon_skip_380242chr3:186784961-186785101-14.29-0.1074EIF4A2ENST00000323963Frame-shift
ENSG00000203499ENST00000534398exon_skip_382356chr3:37091466-37091538-18.48-0.3487LRRFIP2ENST00000336686In-frame
ENSG00000203499ENST00000534398exon_skip_499542chr9:128247923-128247935-3.10-0.6200DNM1ENST00000372923In-frame
ENSG00000203499ENST00000534398exon_skip_11256chr1:155061414-155061489-16.46-0.2572ADAM15ENST00000356955In-frame
ENSG00000203499ENST00000534398exon_skip_153096chr17:44074968-44075087-17.48-0.1604G6PC3ENST00000269097Frame-shift
ENSG00000203499ENST00000534398exon_skip_305632chr19:35262545-35262692-28.18-0.2409LSRENST00000361790In-frame
ENSG00000203499ENST00000534398exon_skip_353395chr20:62130218-62130296-14.28-0.1855LSM14BENST00000279068In-frame
ENSG00000203499ENST00000534398exon_skip_71438chr11:60941121-60941290-19.44-0.1332SLC15A3ENST00000227880Frame-shift
ENSG00000203499ENST00000534398exon_skip_154041chr17:50461241-50461370-19.90-0.2073ACSF2ENST00000300441In-frame
ENSG00000203499ENST00000534398exon_skip_305642chr19:35262545-35262692-28.18-0.2409LSRENST00000361790In-frame

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for FAM83H-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types
ENSG00000203499ENSG00000147789ZNF7ENSG00000133740E2F511BRCA,CHOL,COAD,KICH,LUAD,MESO,PAAD,PRAD,READ,STAD,UCEC
ENSG00000203499ENSG00000170631ZNF16ENSG00000133740E2F57BRCA,CHOL,COAD,LUAD,PRAD,READ,STAD
ENSG00000203499ENSG00000196378ZNF34ENSG00000133740E2F55BRCA,CHOL,COAD,KICH,READ
ENSG00000203499ENSG00000147789ZNF7ENSG00000104517UBR515BRCA,CESC,CHOL,COAD,ESCA,HNSC,KIRP,LUAD,LUSC,OV,PAAD,PRAD,READ,STAD,UCEC
ENSG00000203499ENSG00000170631ZNF16ENSG00000104517UBR513BRCA,CESC,CHOL,COAD,ESCA,HNSC,LUAD,LUSC,OV,PAAD,PRAD,READ,STAD
ENSG00000203499ENSG00000187605TET3ENSG00000104517UBR510CESC,CHOL,ESCA,HNSC,KIRP,LUSC,PAAD,PRAD,STAD,UCEC
ENSG00000203499ENSG00000196378ZNF34ENSG00000104517UBR55BRCA,CHOL,COAD,OV,READ
ENSG00000203499ENSG00000147789ZNF7ENSG00000123908AGO213BRCA,CESC,CHOL,HNSC,LUAD,LUSC,MESO,OV,PAAD,PRAD,READ,STAD,UCEC
ENSG00000203499ENSG00000170631ZNF16ENSG00000123908AGO29BRCA,CESC,CHOL,HNSC,LUSC,OV,PAAD,READ,STAD
ENSG00000203499ENSG00000187605TET3ENSG00000123908AGO28CESC,CHOL,HNSC,LUSC,PAAD,PRAD,STAD,UCEC
ENSG00000203499ENSG00000147789ZNF7ENSG00000063244U2AF25CHOL,HNSC,KIRP,PRAD,THCA
ENSG00000203499ENSG00000147789ZNF7ENSG00000130826DKC16CHOL,COAD,HNSC,KIRP,PRAD,STAD
ENSG00000203499ENSG00000187605TET3ENSG00000130826DKC16CHOL,HNSC,KIRP,LUSC,PRAD,STAD
ENSG00000203499ENSG00000147789ZNF7ENSG00000090447TFAP48CHOL,COAD,HNSC,LUSC,PAAD,PRAD,READ,STAD
ENSG00000203499ENSG00000170631ZNF16ENSG00000090447TFAP46CHOL,HNSC,LUSC,PAAD,PRAD,STAD
ENSG00000203499ENSG00000147789ZNF7ENSG00000147601TERF19BRCA,CHOL,COAD,HNSC,KICH,LUAD,LUSC,PRAD,READ
ENSG00000203499ENSG00000170631ZNF16ENSG00000147601TERF18BRCA,CHOL,COAD,HNSC,LUAD,LUSC,PRAD,READ
ENSG00000203499ENSG00000196378ZNF34ENSG00000147601TERF15BRCA,CHOL,COAD,KICH,READ
ENSG00000203499ENSG00000147789ZNF7ENSG00000141568FOXK27BRCA,CHOL,HNSC,KIRP,PRAD,STAD,THYM
ENSG00000203499ENSG00000187605TET3ENSG00000141568FOXK26CHOL,HNSC,KIRP,LUSC,PRAD,STAD
ENSG00000203499ENSG00000147789ZNF7ENSG00000178105DDX105CHOL,COAD,PAAD,STAD,THYM
ENSG00000203499ENSG00000187605TET3ENSG00000121057AKAP15CHOL,HNSC,LUSC,PRAD,STAD

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000203499.9ENST00000533004.4842532
ENSG00000203499.9ENST00000534398.118317332284