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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000271032

Summary for CTD-2527I21.14

check button Gene summary

Gene informationEnsembl ID

ENSG00000271032

Gene symbol

CTD-2527I21.14

Gene name
HGNC
Entrez ID
Gene typeantisense
Synonyms
UniProtAcc

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Structure and expression level for CTD-2527I21.14

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002710322.314527e+012.457690e+005.064344e-014.852928e+001.220000e-067.870000e-06UPCHOL
ENSG000002710324.061163e+011.156428e+001.671420e-016.918837e+004.550000e-122.520000e-11UPLUAD
ENSG000002710321.898049e+011.980800e+001.998562e-019.911123e+003.720000e-236.200000e-22UPCOAD
ENSG000002710322.013288e+012.376096e+003.864051e-016.149234e+007.790000e-102.060000e-08UPREAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002710326.092431e-018.936324e-06CHOL7.023783e-05

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lncRNA-Protein interaction for CTD-2527I21.14

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000168137SETD549.4293.2891Q9C0A6EpiNA
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000146247PHIP47.5195.6186Q8WWQ0EpiNA
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000187605TET337.5493.3907O43151TF,EpiNA
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000167548KMT2D33.4595.8773O14686EpiNA
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000272333KMT2B26.3494.5755Q9UMN6TF,EpiNA
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000114933INO80D42.5290.6126Q53TQ3EpiNA
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000165288BRWD342.3995.9606Q6RI45EpiNA
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000275023MLLT641.6993.0311P55198EpiNA
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000120071KANSL124.3894.0592Q7Z3B3EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000167967E4F146.7593.4456Q66K89TFNA
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000105127AKAP840.7191.1568O43823TFNA
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000187605TET337.5493.0476O43151TF,EpiNA
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000126464PRR1229.3993.1845Q9ULL5TFNA
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000272333KMT2B26.3493.6122Q9UMN6TF,EpiNA
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000198040ZNF8425.3590.4352P51523TFNA
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000278129ZNF85.0390.2423P17098TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000137776SLTM38.0994.4102Q9NWH9RBPENCODE
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000129351ILF322.6391.2061Q12906RBPENCODE
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000133226SRRM121.3394.8668Q8IYB3RBPNA
ENSG00000271032ENST00000605640CTD-2527I21.14ENSG00000167978SRRM212.8895.4109Q9UQ35RBPNA

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lncRNA-DNA interaction for CTD-2527I21.14

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for CTD-2527I21.14

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000271032ENST00000605640exon_skip_382458chr3:38131595-38131638-9.19-0.2785ACAA1ENST00000333167Frame-shift

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for CTD-2527I21.14

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000271032.1ENST00000605640.191472197