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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000259456

Summary for ADNP-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000259456

Gene symbol

ADNP-AS1

Gene nameADNP antisense RNA 1
HGNC

51227

Entrez ID

101927631

Gene typeantisense
SynonymsADNP-AS1|20q13.13
UniProtAcc

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Structure and expression level for ADNP-AS1

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002594565.526448e-018.270603e-05CHOL2.685551e-04

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lncRNA-Protein interaction for ADNP-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000168137SETD5108.5790.3551Q9C0A6EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000146247PHIP107.0993.0476Q8WWQ0EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000132780NASP102.8890.997P49321EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000104320NBN100.891.0035O60934EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000118058KMT2A99.0795.7888Q03164TF,EpiNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000171316CHD795.7594.978Q9P2D1EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000181090EHMT194.8491.1075Q9H9B1EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000196199MPHOSPH894.4692.6255Q99549EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000085224ATRX91.1495.9658P46100EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000185658BRWD190.1695.3062Q9NSI6EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000183337BCOR79.5893.029Q6W2J9EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000147133TAF178.7792.0765P21675EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000131149GSE174.9194.6485Q14687EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000139613SMARCC272.594.9724Q8TAQ2EpiChIP-seq,catRAPID
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000156650KAT6B39.1696.6888Q8WYB5EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000083544TDRD333.492.0419Q9H7E2RBP,EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000117625RCOR329.6290.3089Q9P2K3EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000123636BAZ2B125.9894.1381Q9UIF8TF,EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000025293PHF20122.2690.8073Q9BVI0TF,EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000032219ARID4A107.5493.1151P29374EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000048649RSF1106.8294.947Q96T23EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000054267ARID4B105.2993.4937Q4LE39EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000181555SETD297.9894.3279Q9BYW2EpiNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000005483KMT2E96.0294.8031Q8IZD2EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000145241CENPC95.6491.2886Q03188EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000165671NSD195.4492.1072Q96L73EpiNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000165288BRWD389.7891.91Q6RI45EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000005339CREBBP88.6291.5656Q92793EpiChIP-seq
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000164190NIPBL78.995.9955Q6KC79EpiChIP-seq
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000071794HLTF78.5790.4919Q14527EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000078403MLLT1077.4390.2084P55197EpiNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000168769TET273.1193.7205Q6N021TF,EpiNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000108799EZH170.391.0543Q92800EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000084093REST68.8693.1469Q13127TF,EpiChIP-seq,catRAPID
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000183495EP40063.2495.1586Q96L91EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000083168KAT6A57.7795.1124Q92794EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000171456ASXL140.5191.9286Q8IXJ9EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000141582CBX425.0590.0017O00257EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000149929HIRIP319.792.2786Q9BW71EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000168283BMI111.8690.2116P35226EpiNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000163961RNF1683.990.9289Q8IYW5EpiPredict

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000123636BAZ2B125.9894.4989Q9UIF8TF,EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000102189EEA1123.2392.1847Q15075TFPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000025293PHF20122.2691.7315Q9BVI0TF,EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000144747TMF1108.7793.7176P82094TFPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000118058KMT2A99.0795.9978Q03164TF,EpiNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000130254SAFB294.8794.8452Q14151TF,RBPPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000105127AKAP885.4293.4665O43823TFNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000147124ZNF4175.4590.5611P51814TFNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000168769TET273.1194.0089Q6N021TF,EpiNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000084093REST68.8692.9393Q13127TF,EpiChIP-seq,catRAPID
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000167232ZNF9167.3794.2694Q05481TFNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000198521ZNF4363.6591.337P17038TFNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000117000RLF61.4594.8543Q13129TFPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000126804ZBTB155.4893.8676Q9Y2K1TFPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000125812GZF153.2992.5532Q9H116TFPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000140836ZFHX352.4793.6861Q15911TFChIP-seq
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000198040ZNF8450.3891.0379P51523TFNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000198538ZNF2849.3991.6981P17035TFPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000168795ZBTB540.4791.3789O15062TFPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000065029ZNF7634.4290.2666P36508TFPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000256223ZNF1022.1390.2851P21506TFNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000197857ZNF4418.0291.2871P15621TFNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000105750ZNF8513.1491.6166Q03923TFNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000196378ZNF3412.4892.8522Q8IZ26TFPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000146757ZNF928.9490.9888Q03936TFNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000114126TFDP28.2191.5646Q14188TFPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000175395ZNF254.2390.4417P17030TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000259456ENST00000614698ADNP-AS1ENSG00000004534RBM649.3190.5995P78332RBPPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000056097ZFR123.4194.4033Q96KR1RBPPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000130254SAFB294.8794.5565Q14151TF,RBPPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000198000NOL886.3992.7722Q76FK4RBPPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000106344RBM2882.5192.4407Q9NW13RBPPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000137776SLTM81.195.3985Q9NWH9RBPPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000135870RC3H157.6790.0208Q5TC82RBPPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000133226SRRM136.7594.1255Q8IYB3RBPNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000083544TDRD333.492.3609Q9H7E2RBP,EpiPredict
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000167978SRRM226.7396.1703Q9UQ35RBPNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000116350SRSF421.0692.9Q08170RBPNA
ENSG00000259456ENST00000558899ADNP-AS1ENSG00000121390PSPC110.8292.394Q8WXF1RBPPredict

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lncRNA-DNA interaction for ADNP-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for ADNP-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
SLC16A3,MRPL37,GRK6,TOM1,ARHGDIA,GET3,ETHE1,WBP2,FTH1,MYDGF,YIF1B,COPE,RHOG,CCT7,GAS2L1,AP2S1,ACADS,CYB5R3,CLPP,GAPDH,LMAN2,ECHS1,NCLN,PYGL,GALK1
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000259456ENST00000614698exon_skip_62840chr11:70421469-70421580-11.64-0.1200CTTNENST00000301843In-frame
ENSG00000259456ENST00000614698exon_skip_334375chr2:227347225-227347384-14.44-0.1256MFFENST00000353339In-frame
ENSG00000259456ENST00000614698exon_skip_484062chr8:73030335-73030395-7.32-0.1785TERF1ENST00000276603In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000259456ENST00000558899exon_skip_41841chr10:68756272-68756483-20.88-0.1207CCAR1ENST00000265872Frame-shift
ENSG00000259456ENST00000614698exon_skip_111863chr14:23565815-23565892-13.06-0.2968AP1G2ENST00000308724,ENST00000397120Frame-shift
ENSG00000259456ENST00000614698exon_skip_114365chr14:74290026-74290118-11.35-0.1599ABCD4ENST00000356924Frame-shift
ENSG00000259456ENST00000614698exon_skip_133217chr16:8635038-8635079-8.40-0.5250METTL22ENST00000381920Frame-shift
ENSG00000259456ENST00000614698exon_skip_139422chr16:89114338-89114487-20.68-0.1532ACSF3ENST00000317447,ENST00000406948Frame-shift
ENSG00000259456ENST00000614698exon_skip_300663chr19:1425877-1425960-8.74-0.1784DAZAP1ENST00000233078Frame-shift
ENSG00000259456ENST00000614698exon_skip_327748chr2:95410863-95411026-18.73-0.1523FAHD2AENST00000233379,ENST00000447036Frame-shift
ENSG00000259456ENST00000614698exon_skip_382458chr3:38131595-38131638-7.43-0.2858ACAA1ENST00000333167Frame-shift
ENSG00000259456ENST00000614698exon_skip_470226chr7:103307595-103307708-10.40-0.1677PMPCBENST00000249269Frame-shift
ENSG00000259456ENST00000558899exon_skip_327433chr2:86125794-86125880-7.54-0.1047PTCD3ENST00000254630Frame-shift
ENSG00000259456ENST00000614698exon_skip_5818chr1:45568484-45568684-27.62-0.1526AKR1A1ENST00000351829,ENST00000372070Frame-shift

check buttonlncRNA targets by miRNA.
lncRNA targets by miRNA
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source
ENSG00000259456hsa-mir-511ENST00000558899chr20:50931503-50931581185.00-55.0285NA
ENSG00000259456hsa-mir-511ENST00000558899chr20:50931671-50931756177.00-57.4588NA
ENSG00000259456hsa-mir-511ENST00000558899chr20:50931376-50931463169.00-65.8186NA
ENSG00000259456hsa-mir-511ENST00000558899chr20:50931186-50931274162.00-68.4566NA
ENSG00000259456hsa-mir-511ENST00000558899chr20:50931577-50931669161.00-52.9588NA
ENSG00000259456hsa-mir-511ENST00000558899chr20:50931103-50931182151.00-59.2955NA
ENSG00000259456hsa-mir-511ENST00000558899chr20:50931774-50931862142.00-52.2588NA
ENSG00000259456hsa-mir-511ENST00000614698chr20:50931373-50931460169.00-65.8186NA
ENSG00000259456hsa-mir-511ENST00000614698chr20:50931183-50931271162.00-68.4566NA
ENSG00000259456hsa-mir-511ENST00000614698chr20:50931100-50931179151.00-59.2955NA

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Variants for ADNP-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000259456.3ENST00000558899.2124524150
ENSG00000259456.3ENST00000614698.161305490