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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000258708

Summary for SLC25A21-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000258708

Gene symbol

SLC25A21-AS1

Gene nameSLC25A21 antisense RNA 1
HGNC

44298

Entrez ID

100129794

Gene typeantisense
SynonymsSLC25A21-AS1|14q13.3
UniProtAcc

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Structure and expression level for SLC25A21-AS1

check buttonDifferentially expressed gene analysis between cancer and normal samples.
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG00000258708-3.541318e-016.624036e-04KICH9.483078e-04

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lncRNA-Protein interaction for SLC25A21-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000258708ENST00000556667SLC25A21-AS1ENSG00000236287ZBED541.0390.0625Q49AG3TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for SLC25A21-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for SLC25A21-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
DPP3,HCK,TAGLN2,TPM3,SELPLG,CD86,C2,KPNA2,ITGB2,ARPC1B,MAN2B1,EFHD2,CTSB,TUBA1C,SEC61A1,SPI1,ACTR3
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000258708ENST00000556667exon_skip_150854chr17:32366664-32366757-13.77-0.1886ZNF207ENST00000321233In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000258708ENST00000556667exon_skip_111863chr14:23565815-23565892-20.26-0.3823AP1G2ENST00000308724,ENST00000397120Frame-shift
ENSG00000258708ENST00000556667exon_skip_41841chr10:68756272-68756483-24.39-0.1270CCAR1ENST00000265872Frame-shift

check buttonlncRNA targets by miRNA.
lncRNA targets by miRNA
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source
ENSG00000258708hsa-mir-142ENST00000556667chr14:37172068-37172155172.00-73.1387NA
ENSG00000258708hsa-mir-142ENST00000556667chr14:37172804-37172888158.00-76.7786NA
ENSG00000258708hsa-mir-142ENST00000556667chr14:37173150-37173234155.00-77.7488NA
ENSG00000258708hsa-mir-142ENST00000556667chr14:37172569-37172656150.00-87.4690NA
ENSG00000258708hsa-mir-142ENST00000556667chr14:37172411-37172494147.00-84.1588NA
ENSG00000258708hsa-mir-142ENST00000556667chr14:37173666-37173751145.00-68.8483NA
ENSG00000258708hsa-mir-142ENST00000556667chr14:37173013-37173103141.00-73.0886NA
ENSG00000258708hsa-mir-185ENST00000556667chr14:37172053-37172138198.00-85.9382NA
ENSG00000258708hsa-mir-185ENST00000556667chr14:37172597-37172675198.00-81.0983NA
ENSG00000258708hsa-mir-185ENST00000556667chr14:37172220-37172301177.00-91.4879NA
ENSG00000258708hsa-mir-185ENST00000556667chr14:37172499-37172581177.00-105.0486NA
ENSG00000258708hsa-mir-185ENST00000556667chr14:37172792-37172865157.00-75.7075NA
ENSG00000258708hsa-mir-185ENST00000556667chr14:37172328-37172409153.00-95.9375NA
ENSG00000258708hsa-mir-185ENST00000556667chr14:37173229-37173312146.00-69.1882NA
ENSG00000258708hsa-mir-185ENST00000556667chr14:37173133-37173209144.00-76.7370NA
ENSG00000258708hsa-mir-21ENST00000556667chr14:37172423-37172488184.00-67.8270NA
ENSG00000258708hsa-mir-21ENST00000556667chr14:37173588-37173660177.00-61.0473NA
ENSG00000258708hsa-mir-21ENST00000556667chr14:37171982-37172051171.00-65.5867NA
ENSG00000258708hsa-mir-21ENST00000556667chr14:37173081-37173147167.00-59.8667NA
ENSG00000258708hsa-mir-21ENST00000556667chr14:37172847-37172920164.00-52.8375NA
ENSG00000258708hsa-mir-21ENST00000556667chr14:37173732-37173804157.00-54.7472NA
ENSG00000258708hsa-mir-21ENST00000556667chr14:37172684-37172754156.00-65.4375NA
ENSG00000258708hsa-mir-21ENST00000556667chr14:37173351-37173422155.00-54.5370NA
ENSG00000258708hsa-mir-21ENST00000556667chr14:37172550-37172615151.00-68.4765NA
ENSG00000258708hsa-mir-21ENST00000556667chr14:37173177-37173248151.00-59.0171NA
ENSG00000258708hsa-mir-21ENST00000556667chr14:37172926-37173006147.00-65.8777NA
ENSG00000258708hsa-mir-21ENST00000556667chr14:37173416-37173487146.00-52.8068NA
ENSG00000258708hsa-mir-21ENST00000556667chr14:37172134-37172210144.00-67.6474NA
ENSG00000258708hsa-mir-21ENST00000556667chr14:37172256-37172334142.00-72.9678NA
ENSG00000258708hsa-mir-21ENST00000556667chr14:37173668-37173731141.00-55.2769NA
ENSG00000258708hsa-mir-1307ENST00000556667chr14:37172478-37172628242.00-146.72152NA
ENSG00000258708hsa-mir-1307ENST00000556667chr14:37173502-37173660230.00-111.86160NA
ENSG00000258708hsa-mir-1307ENST00000556667chr14:37172816-37172960222.00-106.66151NA
ENSG00000258708hsa-mir-1307ENST00000556667chr14:37171942-37172088217.00-131.26148NA
ENSG00000258708hsa-mir-1307ENST00000556667chr14:37172253-37172425214.00-157.14176NA
ENSG00000258708hsa-mir-1307ENST00000556667chr14:37173047-37173211213.00-125.26163NA
ENSG00000258708hsa-mir-1307ENST00000556667chr14:37172628-37172791190.00-140.51161NA
ENSG00000258708hsa-mir-1307ENST00000556667chr14:37173319-37173480181.00-109.69162NA
ENSG00000258708hsa-mir-1307ENST00000556667chr14:37172127-37172260144.00-125.68136NA
ENSG00000258708hsa-mir-942ENST00000556667chr14:37172579-37172663192.00-91.8976NA
ENSG00000258708hsa-mir-942ENST00000556667chr14:37172711-37172799188.00-93.8793NA
ENSG00000258708hsa-mir-942ENST00000556667chr14:37173349-37173432183.00-78.2482NA
ENSG00000258708hsa-mir-942ENST00000556667chr14:37172832-37172915168.00-78.9284NA
ENSG00000258708hsa-mir-942ENST00000556667chr14:37172178-37172259167.00-92.9383NA
ENSG00000258708hsa-mir-942ENST00000556667chr14:37173177-37173266167.00-82.0989NA
ENSG00000258708hsa-mir-942ENST00000556667chr14:37173259-37173356166.00-77.0393NA
ENSG00000258708hsa-mir-942ENST00000556667chr14:37172496-37172590156.00-112.6891NA
ENSG00000258708hsa-mir-942ENST00000556667chr14:37172926-37173005151.00-87.4683NA
ENSG00000258708hsa-mir-942ENST00000556667chr14:37173703-37173795149.00-81.0591NA
ENSG00000258708hsa-mir-942ENST00000556667chr14:37172327-37172424146.00-111.3986NA
ENSG00000258708hsa-mir-942ENST00000556667chr14:37173573-37173655144.00-85.4383NA
ENSG00000258708hsa-mir-942ENST00000556667chr14:37173081-37173171142.00-92.3984NA
ENSG00000258708hsa-mir-942ENST00000556667chr14:37173442-37173522141.00-76.7480NA
ENSG00000258708hsa-mir-4677ENST00000556667chr14:37173679-37173756206.00-53.7779NA
ENSG00000258708hsa-mir-4677ENST00000556667chr14:37172581-37172655181.00-64.2372NA
ENSG00000258708hsa-mir-4677ENST00000556667chr14:37172889-37172963178.00-50.3678NA
ENSG00000258708hsa-mir-4677ENST00000556667chr14:37171924-37171998176.00-53.7777NA
ENSG00000258708hsa-mir-4677ENST00000556667chr14:37173112-37173204163.00-68.3390NA
ENSG00000258708hsa-mir-4677ENST00000556667chr14:37173026-37173106155.00-50.4976NA
ENSG00000258708hsa-mir-4677ENST00000556667chr14:37172334-37172416152.00-74.2279NA
ENSG00000258708hsa-mir-4677ENST00000556667chr14:37172252-37172338141.00-75.0183NA

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Variants for SLC25A21-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types
ENSG00000258708SLC25A21-AS1,hsa-mir-142,TOM1L2THCA,LGG,SARC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-142,CRY2BRCA,LGG,SARC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-142,TEFKICH,THCA,SARC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-142,CASKIN2THCA,LGG,SARC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-142,KLHDC1BRCA,LGG,SARC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-142,PAK4PCPG,KICH,THCA,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-142,PRDM11THCA,LGG,SARC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-142,ZFP2BRCA,THCA,LGG,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-142,MAGI1KICH,BRCA,THCA,SARC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-21,GDAP1PCPG,THCA,LGG,UCS,SARC
ENSG00000258708SLC25A21-AS1,hsa-mir-1307,ANKRA2KICH,BRCA,LGG,SARC,THYM
ENSG00000258708SLC25A21-AS1,hsa-mir-942,KLHDC1KICH,BRCA,LGG,SARC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-185,EPC2KICH,UCS,SARC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-185,MYO9AKICH,UCS,SARC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-185,PRKAA2KICH,UCS,SARC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-185,BAZ2BKICH,UCS,SARC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-185,OBSL1KICH,UCS,SARC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-185,BMPR2KICH,UCS,SARC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-185,MARF1KICH,UCS,SARC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-185,LTBP3KICH,UCS,SARC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-185,CASKIN2KICH,UCS,SARC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-185,ZFP28KICH,UCS,SARC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-185,KMT2EKICH,UCS,SARC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-4677,CGRRF1BRCA,LGG,ACC,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-4677,CRY2BRCA,LGG,ACC,UCS,THYM,KIRP
ENSG00000258708SLC25A21-AS1,hsa-mir-4677,CALCOCO1BRCA,LGG,ACC,UCS,KIRP

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000258708.1ENST00000556667.165523326