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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000245573

Summary for BDNF-AS

check button Gene summary

Gene informationEnsembl ID

ENSG00000245573

Gene symbol

BDNF-AS

Gene nameBDNF antisense RNA
HGNC

20608

Entrez ID

497258

Gene typeantisense
Synonyms11p14.1|BDNF-AS
UniProtAcc

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Structure and expression level for BDNF-AS

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG00000245573-3.828509e-012.131683e-04KICH3.388829e-04

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lncRNA-Protein interaction for BDNF-AS

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000245573ENST00000530686BDNF-ASENSG00000123636BAZ2B113.3695.8216Q9UIF8TF,EpiNA
ENSG00000245573ENST00000530686BDNF-ASENSG00000116539ASH1L76.3893.807Q9NR48TF,EpiNA
ENSG00000245573ENST00000501176BDNF-ASENSG00000123636BAZ2B120.1394.8081Q9UIF8TF,EpiNA
ENSG00000245573ENST00000530313BDNF-ASENSG00000123636BAZ2B91.2394.6201Q9UIF8TF,EpiNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000123636BAZ2B84.7296.3157Q9UIF8TF,EpiNA
ENSG00000245573ENST00000501176BDNF-ASENSG00000116539ASH1L76.8195.0133Q9NR48TF,EpiNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000156256USP1660.6393.0503Q9Y5T5EpiNA
ENSG00000245573ENST00000530313BDNF-ASENSG00000116539ASH1L60.3494.4905Q9NR48TF,EpiNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000116539ASH1L58.6593.6406Q9NR48TF,EpiNA
ENSG00000245573ENST00000501176BDNF-ASENSG00000015171ZMYND116.1890.6381Q15326EpiChIP-seq

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000245573ENST00000501663BDNF-ASENSG00000236287ZBED559.5491.1409Q49AG3TFNA
ENSG00000245573ENST00000530686BDNF-ASENSG00000123636BAZ2B113.3694.6818Q9UIF8TF,EpiNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000123636BAZ2B82.5296.8021Q9UIF8TF,EpiNA
ENSG00000245573ENST00000530686BDNF-ASENSG00000116539ASH1L76.3893.9169Q9NR48TF,EpiNA
ENSG00000245573ENST00000530686BDNF-ASENSG00000196867ZFP2873.0492.4991Q8NHY6TFNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000116539ASH1L55.5996.1829Q9NR48TF,EpiNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000196867ZFP2853.2494.6595Q8NHY6TFNA
ENSG00000245573ENST00000530686BDNF-ASENSG00000166432ZMAT134.8190.0482Q5H9K5TFNA
ENSG00000245573ENST00000530686BDNF-ASENSG00000105708ZNF1425.390.7704P17017TFNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000062194GPBP123.4595.034Q86WP2TFNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000105708ZNF1422.3492.9149P17017TFNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000142065ZFP1419.6394.5163Q9HCL3TFNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000065029ZNF7615.4195.1257P36508TFNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000132846ZBED315.0891.7704Q96IU2TFNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000109381ELF212.2492.5246Q15723TFChIP-seq
ENSG00000245573ENST00000499568BDNF-ASENSG00000095574IKZF58.1890.4728Q9H5V7TFNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000186130ZBTB66.4391.4126Q15916TFNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000175395ZNF255.3895.2619P17030TFNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000275111ZNF23.694.5035Q9BSG1TFNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000198939ZFP21.2793.3388Q6ZN57TFNA
ENSG00000245573ENST00000501176BDNF-ASENSG00000123636BAZ2B120.1395.216Q9UIF8TF,EpiNA
ENSG00000245573ENST00000530313BDNF-ASENSG00000123636BAZ2B91.2394.9296Q9UIF8TF,EpiNA
ENSG00000245573ENST00000501176BDNF-ASENSG00000196867ZFP2888.2391.0109Q8NHY6TFNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000123636BAZ2B84.7295.9496Q9UIF8TF,EpiNA
ENSG00000245573ENST00000501176BDNF-ASENSG00000116539ASH1L76.8194.8705Q9NR48TF,EpiNA
ENSG00000245573ENST00000530313BDNF-ASENSG00000196867ZFP2861.9892.2435Q8NHY6TFNA
ENSG00000245573ENST00000530313BDNF-ASENSG00000116539ASH1L60.3494.4584Q9NR48TF,EpiNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000116539ASH1L58.6593.3991Q9NR48TF,EpiNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000236287ZBED553.2691.3291Q49AG3TFNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000105708ZNF1426.6393.4742P17017TFNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000142065ZFP1425.8291.6649Q9HCL3TFNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000062194GPBP125.793.7172Q86WP2TFNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000065029ZNF7617.0192.9186P36508TFNA
ENSG00000245573ENST00000501176BDNF-ASENSG00000105708ZNF1416.8990.3278P17017TFNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000109381ELF214.6192.3552Q15723TFChIP-seq
ENSG00000245573ENST00000499008BDNF-ASENSG00000095574IKZF59.3890.7609Q9H5V7TFNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000175395ZNF256.1891.4131P17030TFNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000275111ZNF26.1291.2361Q9BSG1TFNA
ENSG00000245573ENST00000530313BDNF-ASENSG00000275111ZNF23.0990.6656Q9BSG1TFNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000198939ZFP21.7492.3922Q6ZN57TFNA
ENSG00000245573ENST00000530313BDNF-ASENSG00000065029ZNF761.4791.6802P36508TFNA
ENSG00000245573ENST00000530313BDNF-ASENSG00000198939ZFP21.2190.334Q6ZN57TFNA
ENSG00000245573ENST00000530313BDNF-ASENSG00000186130ZBTB60.9990.3867Q15916TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000245573ENST00000501176BDNF-ASENSG00000056097ZFR123.5992.5056Q96KR1RBPNA
ENSG00000245573ENST00000530313BDNF-ASENSG00000056097ZFR90.8892.3495Q96KR1RBPNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000056097ZFR86.6395.4833Q96KR1RBPNA
ENSG00000245573ENST00000501176BDNF-ASENSG00000213079SCAF885.1492.9243Q9UPN6RBPNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000159082SYNJ167.6695.1685O43426RBPNA
ENSG00000245573ENST00000530313BDNF-ASENSG00000213079SCAF865.0395.5243Q9UPN6RBPNA
ENSG00000245573ENST00000501176BDNF-ASENSG00000125676THOC262.7592.7458Q8NI27RBPNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000213079SCAF860.5493.4344Q9UPN6RBPNA
ENSG00000245573ENST00000501176BDNF-ASENSG00000135870RC3H154.9491.7611Q5TC82RBPNA
ENSG00000245573ENST00000501176BDNF-ASENSG00000107864CPEB345.4790.8563Q8NE35RBPNA
ENSG00000245573ENST00000530313BDNF-ASENSG00000135870RC3H141.9394.0029Q5TC82RBPNA
ENSG00000245573ENST00000530313BDNF-ASENSG00000107864CPEB340.9991.6373Q8NE35RBPNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000135870RC3H140.4391.831Q5TC82RBPNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000173914RBM4B24.4190.9783Q9BQ04RBPNA
ENSG00000245573ENST00000499008BDNF-ASENSG00000107164FUBP39.2892.9885Q96I24RBPNA
ENSG00000245573ENST00000530313BDNF-ASENSG00000107164FUBP33.0391.4887Q96I24RBPNA
ENSG00000245573ENST00000530313BDNF-ASENSG00000174720LARP70.0693.9055Q4G0J3RBPNA
ENSG00000245573ENST00000530686BDNF-ASENSG00000056097ZFR110.4391.5082Q96KR1RBPNA
ENSG00000245573ENST00000500662BDNF-ASENSG00000056097ZFR108.1690.2515Q96KR1RBPNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000056097ZFR80.0496.168Q96KR1RBPNA
ENSG00000245573ENST00000530686BDNF-ASENSG00000163728TTC1479.5792.0151Q96N46RBPNA
ENSG00000245573ENST00000530686BDNF-ASENSG00000125676THOC268.7591.5395Q8NI27RBPNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000159082SYNJ164.2393.6361O43426RBPNA
ENSG00000245573ENST00000530686BDNF-ASENSG00000135870RC3H152.3191.3931Q5TC82RBPNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000107864CPEB341.3792.9974Q8NE35RBPNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000135870RC3H138.3595.0172Q5TC82RBPNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000173914RBM4B25.2791.1779Q9BQ04RBPNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000174720LARP712.6894.958Q4G0J3RBPNA
ENSG00000245573ENST00000499568BDNF-ASENSG00000107164FUBP34.2193.0533Q96I24RBPNA
ENSG00000245573ENST00000530686BDNF-ASENSG00000107164FUBP32.9590.6291Q96I24RBPNA

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lncRNA-DNA interaction for BDNF-AS

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
KRCC1,C11orf1,RAB28,RNF141,PEX2,RCBTB1,MFSD8,TAF9B,ANGEL2,ATPSCKMT,FASTKD3,LIFR,TMEM267,DYNC2LI1,MCEE,FAM120B,SIRT3,ZNF2,KAT7,C12orf29,RNF170,ARV1,SPIN3,OSCP1,IFT88,FAM120AOS,GABPA,IKZF5,TCAIM,KLHDC1,TTC30B,DCAKD,TTC19,ZFP14,RHOT1,RNPC3,WDR5B,GORASP1,INCA1,ZMYND12,ZNF25,LARP7,ARAP2,ABITRAM,KBTBD3,SLC18B1,ZBED5,TMEM220,CLN5,ODR4,CTSO,OSGEPL1,TTC14,ZBED3,STK33,GKAP1,RC3H1,IQCA1,ORC3,DPY19L4,FAM104B,DENND11,RBM4B,ELP4,ANAPC13,TCTA,ASH1L,SLC39A9,UTP14C,BBS10,PRIMPOL,RBM43,ANAPC10,ALDH7A1,TTC30A,THAP9,THOC2,GLT8D1,ZBTB6,FBXO8,HDHD2,ANKRD46,FBXO3,THAP6,SEC62,C4orf33,TMEM9B,SAP30L,SLC35A5,SBDS,BBS12,LIAS,TMEM128,REEP5,KLF15,GNPDA2,DZIP3,NBR1,PNPLA8,SEC63,APPL2,ANKRA2,KCTD18,C2orf49,VPS52,FAXDC2,COQ7,CCDC121,CETN3,PEX11A,YAE1,FAM149B1,RBM18,UNC50,CRYZL1,TMEM87A,DCUN1D1,DNAJC18,SALL2,FAM229B,ZMAT1,ZFR,ADHFE1,CBR4,MOCS2,SYNJ1,CRCP,GPBP1,DIABLO,MFF,PLSCR4,ZNF14,SCRN3,GIN1,LIPT1,CPEB3,ELF2,NDUFA5,LYRM7,SMAD4,NUDCD2,UEVLD,ZFP28,DMAC2L,COA5,CRBN,ALDH9A1,ERCC8,STXBP3,GSTA4,MICU2,BBS4,BAZ2B,TMEM50B,SNX13,PIK3C2A,USP16,FBXO36,DNAJC24,PCBD2,MRPS14,NDRG2,ETFRF1,LRRC6,RCBTB2,RCHY1,TBC1D5,LIN7C,WBP1,NUCKS1,TRMT10A,MRFAP1L1
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for BDNF-AS

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
TRPV2,NCLN
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for BDNF-AS

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000245573.6ENST00000530686.48317268
ENSG00000245573.6ENST00000532965.469488279
ENSG00000245573.6ENST00000501176.56362253
ENSG00000245573.6ENST00000499008.6145799362
ENSG00000245573.6ENST00000502161.511120991764
ENSG00000245573.6ENST00000500662.5119652293
ENSG00000245573.6ENST00000499568.2145730293
ENSG00000245573.6ENST00000530313.1831061810
ENSG00000245573.6ENST00000501663.273154375