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lncRNA: ENSG00000245060

Summary for LINC00847

Gene summary

Gene information	Ensembl ID	ENSG00000245060
	Gene symbol	LINC00847
	Gene name	long intergenic non-protein coding RNA 847
	HGNC	45050
	Entrez ID	729678
	Gene type	lincRNA
	Synonyms	LINC00847\|05q35.3
	UniProtAcc

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Structure and expression level for LINC00847

AS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID

Base mean

log2FC(AD/control)

lfcSE

Stat

P-value

Adjc.p-value

DEG direction

Cancer type

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000245060	5.271445e-01	1.988507e-04	CHOL	5.079206e-04
ENSG00000245060	3.691269e-01	2.337102e-14	LIHC	2.447342e-13

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lncRNA-Protein interaction for LINC00847

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000245060	ENST00000501855	LINC00847	ENSG00000204231	RXRB	30.61	91.9375	P28702	TF	NA
ENSG00000245060	ENST00000502162	LINC00847	ENSG00000130254	SAFB2	45.97	93.3696	Q14151	TF,RBP	NA
ENSG00000245060	ENST00000501937	LINC00847	ENSG00000204231	RXRB	37.87	92.5415	P28702	TF	NA
ENSG00000245060	ENST00000502162	LINC00847	ENSG00000198521	ZNF43	30.77	90.5424	P17038	TF	NA
ENSG00000245060	ENST00000502162	LINC00847	ENSG00000180787	ZFP3	30.04	91.0872	Q96NJ6	TF	NA
ENSG00000245060	ENST00000502162	LINC00847	ENSG00000180035	ZNF48	29.78	91.7009	Q96MX3	TF	NA
ENSG00000245060	ENST00000502162	LINC00847	ENSG00000125812	GZF1	29.12	92.9183	Q9H116	TF	NA
ENSG00000245060	ENST00000502162	LINC00847	ENSG00000196670	ZFP62	25.73	92.5701	Q8NB50	TF	NA
ENSG00000245060	ENST00000502162	LINC00847	ENSG00000198040	ZNF84	22.54	91.7045	P51523	TF	ChIP-seq
ENSG00000245060	ENST00000502162	LINC00847	ENSG00000114439	BBX	21.54	90.2116	Q8WY36	TF	NA
ENSG00000245060	ENST00000501937	LINC00847	ENSG00000135457	TFCP2	21.22	90.475	Q12800	TF	NA
ENSG00000245060	ENST00000502162	LINC00847	ENSG00000186272	ZNF17	17.27	90.4618	P17021	TF	NA
ENSG00000245060	ENST00000502162	LINC00847	ENSG00000168661	ZNF30	13.0	90.4693	P17039	TF	NA
ENSG00000245060	ENST00000502162	LINC00847	ENSG00000146757	ZNF92	10.78	91.0658	Q03936	TF	NA
ENSG00000245060	ENST00000502162	LINC00847	ENSG00000196152	ZNF79	6.11	90.1026	Q15937	TF	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000245060	ENST00000502162	LINC00847	ENSG00000198000	NOL8	46.19	91.5024	Q76FK4	RBP	NA
ENSG00000245060	ENST00000502162	LINC00847	ENSG00000130254	SAFB2	45.97	92.2443	Q14151	TF,RBP	NA
ENSG00000245060	ENST00000501937	LINC00847	ENSG00000091009	RBM27	44.02	91.84	Q9P2N5	RBP	NA
ENSG00000245060	ENST00000502162	LINC00847	ENSG00000100461	RBM23	7.28	90.7672	Q86U06	RBP	NA
ENSG00000245060	ENST00000501855	LINC00847	ENSG00000091009	RBM27	40.16	90.2703	Q9P2N5	RBP	NA
ENSG00000245060	ENST00000501855	LINC00847	ENSG00000100461	RBM23	7.33	92.485	Q86U06	RBP	NA

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lncRNA-DNA interaction for LINC00847

lncRNA targets the enhancer region and positively regulates the gene expression.

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for LINC00847

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

Only predicted by lncTar

KLF16

Exist in public source

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

lncRNA and exonskipping events positive correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	ORF mutation
ENSG00000245060	ENST00000501937	exon_skip_368285	chr22:29329711-29329720	-2.82	-0.5640	AP1B1	ENST00000357586,ENST00000405198	In-frame
ENSG00000245060	ENST00000501937	exon_skip_52894	chr10:98431130-98431291	-28.82	-0.1961	HPS1	ENST00000325103,ENST00000361490	Frame-shift
ENSG00000245060	ENST00000501937	exon_skip_150854	chr17:32366664-32366757	-10.29	-0.1303	ZNF207	ENST00000321233	In-frame
ENSG00000245060	ENST00000501937	exon_skip_298575	chr18:26035830-26035923	-13.64	-0.1921	SS18	ENST00000415083	In-frame

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000245060	ENST00000501937	exon_skip_482403	chr8:27445793-27445919	-18.72	-0.1614	PTK2B	ENST00000346049,ENST00000397501	In-frame
ENSG00000245060	ENST00000501937	exon_skip_114200	chr14:73279280-73279424	-21.04	-0.1514	NUMB	ENST00000355058,ENST00000555238	In-frame

lncRNA targets by miRNA.

LncRNA Ensembl ID	miRNA ID	LncRNA ENST ID	Binding site in lncRNA	Score	Energy	Align Len	Public source
ENSG00000245060	hsa-mir-31	ENST00000501855	chr5:180832574-180832645	203.00	-58.31	67	NA
ENSG00000245060	hsa-mir-31	ENST00000501855	chr5:180831249-180831324	185.00	-63.16	67	NA
ENSG00000245060	hsa-mir-31	ENST00000501855	chr5:180832300-180832372	176.00	-61.91	70	NA
ENSG00000245060	hsa-mir-31	ENST00000501855	chr5:180831409-180831481	175.00	-61.04	72	NA
ENSG00000245060	hsa-mir-31	ENST00000501855	chr5:180831983-180832051	167.00	-56.90	71	NA
ENSG00000245060	hsa-mir-31	ENST00000501855	chr5:180832491-180832564	162.00	-57.92	67	NA
ENSG00000245060	hsa-mir-31	ENST00000501855	chr5:180830958-180831000	159.00	-53.76	47	NA
ENSG00000245060	hsa-mir-31	ENST00000501855	chr5:180832070-180832147	158.00	-62.40	74	NA
ENSG00000245060	hsa-mir-31	ENST00000501855	chr5:180831772-180831839	154.00	-51.64	73	NA
ENSG00000245060	hsa-mir-31	ENST00000501855	chr5:180831316-180831390	151.00	-57.87	67	NA
ENSG00000245060	hsa-mir-31	ENST00000501855	chr5:180831112-180831184	150.00	-69.43	68	NA
ENSG00000245060	hsa-mir-31	ENST00000501855	chr5:180831525-180831593	149.00	-57.32	72	NA
ENSG00000245060	hsa-mir-31	ENST00000501855	chr5:180831612-180831690	141.00	-60.51	75	NA
ENSG00000245060	hsa-mir-31	ENST00000502162	chr5:180832579-180832650	203.00	-58.31	67	NA
ENSG00000245060	hsa-mir-31	ENST00000502162	chr5:180832305-180832377	176.00	-61.91	70	NA
ENSG00000245060	hsa-mir-31	ENST00000502162	chr5:180831414-180831486	175.00	-61.04	72	NA
ENSG00000245060	hsa-mir-31	ENST00000502162	chr5:180831988-180832056	167.00	-56.90	71	NA
ENSG00000245060	hsa-mir-31	ENST00000502162	chr5:180832496-180832569	162.00	-57.92	67	NA
ENSG00000245060	hsa-mir-31	ENST00000502162	chr5:180832075-180832152	158.00	-62.40	74	NA
ENSG00000245060	hsa-mir-31	ENST00000502162	chr5:180831777-180831844	154.00	-51.64	73	NA
ENSG00000245060	hsa-mir-31	ENST00000502162	chr5:180831112-180831184	150.00	-69.43	68	NA
ENSG00000245060	hsa-mir-31	ENST00000502162	chr5:180831530-180831598	149.00	-57.32	72	NA
ENSG00000245060	hsa-mir-31	ENST00000502162	chr5:180831617-180831695	141.00	-60.51	75	NA
ENSG00000245060	hsa-mir-31	ENST00000508309	chr5:180831226-180831298	175.00	-61.04	72	NA
ENSG00000245060	hsa-mir-31	ENST00000508309	chr5:180831589-180831656	154.00	-51.64	73	NA
ENSG00000245060	hsa-mir-31	ENST00000508309	chr5:180831112-180831184	150.00	-69.43	68	NA
ENSG00000245060	hsa-mir-31	ENST00000508309	chr5:180831342-180831410	149.00	-57.32	72	NA
ENSG00000245060	hsa-mir-31	ENST00000508309	chr5:180831429-180831507	141.00	-60.51	75	NA
ENSG00000245060	hsa-mir-31	ENST00000509921	chr5:180831173-180831248	177.00	-67.76	66	NA
ENSG00000245060	hsa-mir-31	ENST00000509921	chr5:180831297-180831369	175.00	-61.04	72	NA
ENSG00000245060	hsa-mir-31	ENST00000509921	chr5:180831660-180831727	154.00	-51.64	73	NA
ENSG00000245060	hsa-mir-31	ENST00000509921	chr5:180831112-180831184	150.00	-69.43	68	NA
ENSG00000245060	hsa-mir-31	ENST00000509921	chr5:180831413-180831481	149.00	-57.32	72	NA
ENSG00000245060	hsa-mir-31	ENST00000509921	chr5:180831500-180831578	141.00	-60.51	75	NA
ENSG00000245060	hsa-mir-31	ENST00000501937	chr5:180832968-180833039	203.00	-58.31	67	NA
ENSG00000245060	hsa-mir-31	ENST00000501937	chr5:180831682-180831754	181.00	-58.49	52	NA
ENSG00000245060	hsa-mir-31	ENST00000501937	chr5:180832694-180832766	176.00	-61.91	70	NA
ENSG00000245060	hsa-mir-31	ENST00000501937	chr5:180831803-180831875	175.00	-61.04	72	NA
ENSG00000245060	hsa-mir-31	ENST00000501937	chr5:180832377-180832445	167.00	-56.90	71	NA
ENSG00000245060	hsa-mir-31	ENST00000501937	chr5:180832885-180832958	162.00	-57.92	67	NA
ENSG00000245060	hsa-mir-31	ENST00000501937	chr5:180832464-180832541	158.00	-62.40	74	NA
ENSG00000245060	hsa-mir-31	ENST00000501937	chr5:180832166-180832233	154.00	-51.64	73	NA
ENSG00000245060	hsa-mir-31	ENST00000501937	chr5:180831368-180831447	149.00	-67.29	80	NA
ENSG00000245060	hsa-mir-31	ENST00000501937	chr5:180831919-180831987	149.00	-57.32	72	NA
ENSG00000245060	hsa-mir-31	ENST00000501937	chr5:180832006-180832084	141.00	-60.51	75	NA
ENSG00000245060	hsa-mir-148a	ENST00000501855	chr5:180832413-180832487	175.00	-58.60	71	NA
ENSG00000245060	hsa-mir-148a	ENST00000501855	chr5:180832056-180832131	160.00	-55.01	57	NA
ENSG00000245060	hsa-mir-148a	ENST00000501855	chr5:180831317-180831393	153.00	-54.55	68	NA
ENSG00000245060	hsa-mir-148a	ENST00000501855	chr5:180831598-180831674	149.00	-58.68	63	NA
ENSG00000245060	hsa-mir-148a	ENST00000501855	chr5:180831788-180831851	147.00	-53.95	61	NA
ENSG00000245060	hsa-mir-148a	ENST00000501855	chr5:180831052-180831116	146.00	-60.44	66	NA
ENSG00000245060	hsa-mir-148a	ENST00000501855	chr5:180831157-180831220	146.00	-61.37	64	NA
ENSG00000245060	hsa-mir-148a	ENST00000501855	chr5:180832130-180832197	140.00	-54.81	67	NA
ENSG00000245060	hsa-mir-148a	ENST00000502162	chr5:180832418-180832492	175.00	-58.60	71	NA
ENSG00000245060	hsa-mir-148a	ENST00000502162	chr5:180832061-180832136	160.00	-55.01	57	NA
ENSG00000245060	hsa-mir-148a	ENST00000502162	chr5:180831603-180831679	149.00	-58.68	63	NA
ENSG00000245060	hsa-mir-148a	ENST00000502162	chr5:180831793-180831856	147.00	-53.95	61	NA
ENSG00000245060	hsa-mir-148a	ENST00000502162	chr5:180831052-180831116	146.00	-60.44	66	NA
ENSG00000245060	hsa-mir-148a	ENST00000502162	chr5:180831157-180831220	146.00	-61.37	64	NA
ENSG00000245060	hsa-mir-148a	ENST00000502162	chr5:180831229-180831299	144.00	-62.74	66	NA
ENSG00000245060	hsa-mir-148a	ENST00000502162	chr5:180831338-180831403	144.00	-52.04	66	NA
ENSG00000245060	hsa-mir-148a	ENST00000502162	chr5:180832135-180832202	140.00	-54.81	67	NA
ENSG00000245060	hsa-mir-148a	ENST00000508309	chr5:180831415-180831491	149.00	-58.68	63	NA
ENSG00000245060	hsa-mir-148a	ENST00000508309	chr5:180831605-180831668	147.00	-53.95	61	NA
ENSG00000245060	hsa-mir-148a	ENST00000508309	chr5:180831052-180831116	146.00	-60.44	66	NA
ENSG00000245060	hsa-mir-148a	ENST00000508309	chr5:180831157-180831220	146.00	-61.37	64	NA
ENSG00000245060	hsa-mir-148a	ENST00000509921	chr5:180831486-180831562	149.00	-58.68	63	NA
ENSG00000245060	hsa-mir-148a	ENST00000509921	chr5:180831676-180831739	147.00	-53.95	61	NA
ENSG00000245060	hsa-mir-148a	ENST00000509921	chr5:180831052-180831116	146.00	-60.44	66	NA
ENSG00000245060	hsa-mir-148a	ENST00000509921	chr5:180831157-180831220	146.00	-61.37	64	NA
ENSG00000245060	hsa-mir-148a	ENST00000501937	chr5:180831389-180831456	186.00	-51.04	64	NA
ENSG00000245060	hsa-mir-148a	ENST00000501937	chr5:180832807-180832881	175.00	-58.60	71	NA
ENSG00000245060	hsa-mir-148a	ENST00000501937	chr5:180832450-180832525	160.00	-55.01	57	NA
ENSG00000245060	hsa-mir-148a	ENST00000501937	chr5:180831992-180832068	149.00	-58.68	63	NA
ENSG00000245060	hsa-mir-148a	ENST00000501937	chr5:180832182-180832245	147.00	-53.95	61	NA
ENSG00000245060	hsa-mir-148a	ENST00000501937	chr5:180832524-180832591	140.00	-54.81	67	NA

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Variants for LINC00847

RNA A-to-I editing events in lncRNA.

LncRNAediting ID	LncRNA Ensembl ID	Chromosome	Editing Position	Strand	Gene Type	Gene Name	Transcript ID	Transcript Type	Transcript Name
LncEditing_158033	ENSG00000245060.5	chr5	180835080	+	lincRNA	LINC00847	ENST00000502162.2	lincRNA	LINC00847-003
LncEditing_158072	ENSG00000245060.5	chr5	180835317	+	lincRNA	LINC00847	ENST00000502162.2	lincRNA	LINC00847-003
LncEditing_158075	ENSG00000245060.5	chr5	180835373	+	lincRNA	LINC00847	ENST00000502162.2	lincRNA	LINC00847-003
LncEditing_158078	ENSG00000245060.5	chr5	180835380	+	lincRNA	LINC00847	ENST00000502162.2	lincRNA	LINC00847-003

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID	LncRNA Index	Cancer Type	Chr_Postion_Strand	AVE1	AVE2	log2FC	W-value	P-value	Adjc.p-value	Change
ENSG00000245060	LncEditing_158033	LIHC	chr5_180835080_+	4.404309e+00	1.906916e+00	8.280377e-01	6.699469e+00	2.091785e-11	4.076690e-11	UP
ENSG00000245060	LncEditing_158075	KIRC	chr5_180835373_+	8.428497e+00	5.014713e+00	1.334920e+00	2.552184e+00	1.070499e-02	1.109317e-02	UP
ENSG00000245060	LncEditing_158075	MESO	chr5_180835373_+	6.404257e+00	2.791205e+00	8.346248e-01	2.120353e+00	3.397633e-02	3.510511e-02	UP
ENSG00000245060	LncEditing_158072	BLCA	chr5_180835317_+	8.270605e+00	9.765746e+00	-4.171230e+00	-2.797224e+00	5.154377e-03	5.563454e-03	DOWN
ENSG00000245060	LncEditing_158075	BLCA	chr5_180835373_+	9.675551e+00	5.841895e+00	1.373801e+00	4.263950e+00	2.008441e-05	2.471928e-05	UP
ENSG00000245060	LncEditing_158033	COAD	chr5_180835080_+	4.992689e+00	2.727221e+00	1.146282e+00	1.001597e+01	1.296876e-23	7.465802e-23	UP
ENSG00000245060	LncEditing_158075	COAD	chr5_180835373_+	5.005623e+00	3.254006e+00	1.609443e+00	8.259757e+00	1.459692e-16	3.701363e-16	UP
ENSG00000245060	LncEditing_158033	LAML	chr5_180835080_+	6.428037e+00	3.704127e+00	1.257475e+00	5.001830e+00	5.678856e-07	1.375174e-06	UP
ENSG00000245060	LncEditing_158075	LAML	chr5_180835373_+	6.655502e+00	4.770152e+00	2.081113e+00	5.602544e+00	2.112279e-08	6.975038e-08	UP
ENSG00000245060	LncEditing_158075	OV	chr5_180835373_+	8.942226e+00	4.388613e+00	9.738342e-01	3.109231e+00	1.875751e-03	2.011374e-03	UP
ENSG00000245060	LncEditing_158078	OV	chr5_180835380_+	1.036303e+01	8.592209e+00	3.698973e+00	2.725103e+00	6.428136e-03	6.697645e-03	UP
ENSG00000245060	LncEditing_158075	TGCT	chr5_180835373_+	3.536257e+00	1.511648e+00	8.155938e-01	4.878363e+00	1.069698e-06	1.837972e-06	UP
ENSG00000245060	LncEditing_158033	READ	chr5_180835080_+	4.739200e+00	2.509331e+00	1.090107e+00	6.927998e+00	4.268364e-12	4.078659e-11	UP
ENSG00000245060	LncEditing_158075	READ	chr5_180835373_+	4.690033e+00	3.112781e+00	1.690920e+00	4.941324e+00	7.759403e-07	1.756076e-06	UP
ENSG00000245060	LncEditing_158033	STAD	chr5_180835080_+	4.472762e+00	2.187564e+00	9.691421e-01	6.916131e+00	4.641455e-12	8.620705e-12	UP
ENSG00000245060	LncEditing_158075	STAD	chr5_180835373_+	4.429685e+00	2.705695e+00	1.406065e+00	5.247000e+00	1.545958e-07	2.019902e-07	UP
ENSG00000245060	LncEditing_158075	BRCA	chr5_180835373_+	9.035070e+00	4.349297e+00	9.480887e-01	3.291533e+00	9.964293e-04	1.033387e-03	UP

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID

LncRNA ENST ID

PC Gene Name

PC Gene ID

PC ENST ID

nDG

Cancer with PC gene up-regulation

Cancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000245060.5	ENST00000501855.5	110	507	175
ENSG00000245060.5	ENST00000502162.2	136	10	420
ENSG00000245060.5	ENST00000508309.1	130	727	1119
ENSG00000245060.5	ENST00000509921.1	94	3	287
ENSG00000245060.5	ENST00000501937.2	95	59	346

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential