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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000244055

Summary for AC007566.10

check button Gene summary

Gene informationEnsembl ID

ENSG00000244055

Gene symbol

AC007566.10

Gene name
HGNC
Entrez ID
Gene typeantisense
Synonyms
UniProtAcc

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Structure and expression level for AC007566.10

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002440557.466761e+011.625953e+001.357130e-011.198082e+014.480000e-335.290000e-32UPKIRC

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002440555.220997e-012.346171e-04CHOL5.621452e-04

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lncRNA-Protein interaction for AC007566.10

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000244055ENST00000427458AC007566.10ENSG00000118058KMT2A84.9992.5363Q03164TF,EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000146247PHIP84.6990.9153Q8WWQ0EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000168137SETD584.391.0607Q9C0A6EpiNA
ENSG00000244055ENST00000427458AC007566.10ENSG00000171316CHD780.8692.3745Q9P2D1EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000118058KMT2A80.1596.3648Q03164TF,EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000171316CHD775.1495.0057Q9P2D1EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000196199MPHOSPH873.7590.9199Q99549EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000185658BRWD169.7293.1223Q9NSI6EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000147133TAF161.3990.7768P21675EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000104885DOT1L59.491.8737Q8TEK3TF,EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000139613SMARCC256.894.5117Q8TAQ2EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000171634BPTF56.4994.6629Q12830TF,EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000143442POGZ56.0790.3525Q7Z3K3EpiNA
ENSG00000244055ENST00000427458AC007566.10ENSG00000167548KMT2D54.4892.5653O14686EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000167548KMT2D51.3295.4812O14686EpiNA
ENSG00000244055ENST00000427458AC007566.10ENSG00000120616EPC145.5790.1652Q9H2F5EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000120616EPC144.0892.8399Q9H2F5EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000272333KMT2B41.4291.7043Q9UMN6TF,EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000083544TDRD326.7690.3231Q9H7E2RBP,EpiNA
ENSG00000244055ENST00000427458AC007566.10ENSG00000123636BAZ2B105.9491.1412Q9UIF8TF,EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000123636BAZ2B97.8794.3805Q9UIF8TF,EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000054267ARID4B84.6891.8504Q4LE39EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000032219ARID4A83.9991.4518P29374EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000005483KMT2E76.7894.0669Q8IZD2EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000181555SETD275.9991.5596Q9BYW2EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000275023MLLT675.7291.4561P55198EpiNA
ENSG00000244055ENST00000427458AC007566.10ENSG00000177200CHD974.6490.9129Q3L8U1EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000145241CENPC74.5490.2823Q03188EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000165288BRWD369.5390.2347Q6RI45EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000177200CHD969.4491.1615Q3L8U1EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000055609KMT2C68.0395.391Q8NEZ4EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000076108BAZ2A60.2990.94Q9UIF9TF,RBP,EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000078403MLLT1060.2893.2021P55197EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000168769TET257.9193.776Q6N021TF,EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000108799EZH155.1392.0043Q92800EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000183495EP40049.4493.4747Q96L91EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000120071KANSL135.6690.2703Q7Z3B3EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000171456ASXL132.1492.2341Q8IXJ9EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000244055ENST00000427458AC007566.10ENSG00000123636BAZ2B105.9491.322Q9UIF8TF,EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000102189EEA198.792.02Q15075TFNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000123636BAZ2B97.8794.4441Q9UIF8TF,EpiNA
ENSG00000244055ENST00000427458AC007566.10ENSG00000118058KMT2A84.9992.3396Q03164TF,EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000118058KMT2A80.1596.3282Q03164TF,EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000076108BAZ2A60.2990.8631Q9UIF9TF,RBP,EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000104885DOT1L59.491.986Q8TEK3TF,EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000147124ZNF4158.7990.2341P51814TFNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000168769TET257.9193.6962Q6N021TF,EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000171634BPTF56.4994.6931Q12830TF,EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000167232ZNF9152.8690.8359Q05481TFNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000117000RLF47.8693.4141Q13129TFNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000196670ZFP6245.5790.4556Q8NB50TFNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000272333KMT2B41.4291.7173Q9UMN6TF,EpiNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000244055ENST00000441539AC007566.10ENSG00000198000NOL867.3890.9094Q76FK4RBPNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000137776SLTM63.2291.9614Q9NWH9RBPNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000076108BAZ2A60.2990.9367Q9UIF9TF,RBP,EpiNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000162775RBM1557.1591.8438Q96T37RBPENCODE
ENSG00000244055ENST00000441539AC007566.10ENSG00000133226SRRM128.4593.5377Q8IYB3RBPNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000083544TDRD326.7690.2597Q9H7E2RBP,EpiNA
ENSG00000244055ENST00000427458AC007566.10ENSG00000167978SRRM223.095.5503Q9UQ35RBPNA
ENSG00000244055ENST00000441539AC007566.10ENSG00000167978SRRM221.1396.9146Q9UQ35RBPNA

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lncRNA-DNA interaction for AC007566.10

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for AC007566.10

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
PSMB5,CFL1,ATP6V0D1
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000244055ENST00000441539exon_skip_382458chr3:38131595-38131638-4.85-0.1244ACAA1ENST00000333167Frame-shift
ENSG00000244055ENST00000441539exon_skip_300663chr19:1425877-1425960-8.58-0.1208DAZAP1ENST00000233078Frame-shift
ENSG00000244055ENST00000427458exon_skip_327433chr2:86125794-86125880-5.16-0.1985PTCD3ENST00000254630Frame-shift
ENSG00000244055ENST00000427458exon_skip_442657chr5:74730259-74730398-9.99-0.3568GFM2ENST00000296805,ENST00000509430Frame-shift

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for AC007566.10

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000244055.1ENST00000427458.189712981
ENSG00000244055.1ENST00000441539.114050179