lncRNAfunc Logo

Home

Download

Statistics

Landscape

Help

Contact

Center for Computational Systems Medicine
leaf

lncRNA summary

leaf

lncRNA structure and expression level

leaf

lncRNA-Protein interaction

leaf

lncRNA-DNA interaction

leaf

lncRNA-RNA interaction

leaf

Variants in lncRNA

leaf

lncRNAs regulate the target genes through functioning as enhancers

leaf

lncRNAs regulate the target genes through recruiting transcript factors

leaf

lncRNAs regulate the alternative splicing events through interacting with splicing factor

leaf

lncRNAs regulate mRNA through targeting the 3'-UTR region

leaf

lncRNAs regulate mRNA by competing with miRNA

leaf

lncRNA coding potential

lncRNA: ENSG00000237181

Summary for PRKAR1B-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000237181

Gene symbol

PRKAR1B-AS1

Gene namePRKAR1B antisense RNA 1
HGNC

40470

Entrez ID
Gene typeantisense
Synonyms07p22.3|PRKAR1B-AS1|AC147651.4
UniProtAcc

Top

Structure and expression level for PRKAR1B-AS1

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002371811.075733e+022.863815e+005.034998e-015.687819e+001.290000e-081.630000e-07UPGBM
ENSG000002371811.122723e+022.378991e+001.319767e-011.802584e+011.220000e-726.600000e-71UPKIRC
ENSG000002371817.022411e+011.716543e+002.604547e-016.590563e+004.380000e-113.690000e-10UPKIRP
ENSG000002371816.320686e+01-1.084475e+001.729417e-01-6.270758e+003.590000e-101.270000e-09DOWNLUSC

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002371813.500936e-011.839537e-02CHOL2.017016e-02
ENSG000002371814.702315e-018.947441e-35KIRC1.342116e-32

Top

lncRNA-Protein interaction for PRKAR1B-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

Top

lncRNA-DNA interaction for PRKAR1B-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

Top

lncRNA-RNA interaction for PRKAR1B-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
CNOT1,LRP6,PARG,EPB41L5,ERC1,NEK4,CMTM4,PRKAR2A,L2HGDH,NFAT5,KIF2A,PLS1,CSDE1,EXOC7,SOS2,KTN1,USP9X,MAGI1,RNF123,HACD3,CHP1,HUWE1,LONP2,TAF1,ZMYND11,SERINC5,NAF1,DYNC1LI2,KBTBD4,TOM1L1,DCAF17,USP32,GNL3L,FOXJ3,KIDINS220,NPTN,ATRN,AKAP1,EIF4G1,HECTD1,RAI1,BPTF,DDB1,NCOA2,PBX1,ARHGAP5,DDX3X,RAB11A,PUM1,ALDH7A1,NR2C2,TJP2,ZNF91,BCL2L2,RNF38,SYNJ1,NDUFS1
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000237181ENST00000429872exon_skip_75398chr11:72692752-72692785-12.49-0.4461ARAP1ENST00000393605In-frame
ENSG00000237181ENST00000429872exon_skip_515330chrX:65524563-65524614-10.48-0.5516LAS1LENST00000374811In-frame
ENSG00000237181ENST00000429872exon_skip_368285chr22:29329711-29329720-5.39-0.6737AP1B1ENST00000357586,ENST00000405198In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000237181ENST00000429872exon_skip_60345chr11:63903985-63904147-21.02-0.1314MARK2ENST00000402010In-frame
ENSG00000237181ENST00000429872exon_skip_95025chr12:79805591-79805768-16.91-0.1217PPP1R12AENST00000261207,ENST00000450142In-frame
ENSG00000237181ENST00000429872exon_skip_482403chr8:27445793-27445919-15.67-0.1328PTK2BENST00000346049,ENST00000397501In-frame
ENSG00000237181ENST00000429872exon_skip_2091chr1:17634547-17634562-5.91-2.9550ARHGEF10LENST00000361221In-frame
ENSG00000237181ENST00000429872exon_skip_353131chr20:58669290-58669453-25.71-0.1850STX16ENST00000371141Frame-shift
ENSG00000237181ENST00000429872exon_skip_379903chr3:184180644-184180650-2.01-0.4020AP2M1ENST00000292807In-frame
ENSG00000237181ENST00000429872exon_skip_44853chr10:104010815-104010908-10.24-0.1766SLKENST00000369755In-frame
ENSG00000237181ENST00000429872exon_skip_461111chr6:90544551-90544632-13.37-0.1938MAP3K7ENST00000369329In-frame
ENSG00000237181ENST00000429872exon_skip_64939chr11:112230207-112230230-6.33-2.1100PTSENST00000280362Frame-shift
ENSG00000237181ENST00000429872exon_skip_334374chr2:227347225-227347384-20.83-0.1811MFFENST00000353339In-frame

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

Top

Variants for PRKAR1B-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

Top

lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

Top

lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

Top

lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

Top

lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation
ENSG00000237181ENST00000429872RAI1ENSG00000108557ENST00000353383-0.10261-GBM
ENSG00000237181ENST00000429872RAI1ENSG00000108557ENST00000583166-0.268930-GBM
ENSG00000237181ENST00000429872TJP2ENSG00000119139ENST00000377259-0.12951-GBM
ENSG00000237181ENST00000429872ZMYND11ENSG00000015171ENST00000509513-0.1278101-GBM
ENSG00000237181ENST00000429872ZMYND11ENSG00000015171ENST00000602682-0.238034-GBM
ENSG00000237181ENST00000429872ZMYND11ENSG00000015171ENST00000558098-0.1278101-GBM
ENSG00000237181ENST00000429872RNF123ENSG00000164068ENST00000327697-0.1140448-GBM
ENSG00000237181ENST00000429872RNF123ENSG00000164068ENST00000432042-0.240283-GBM
ENSG00000237181ENST00000429872RNF123ENSG00000164068ENST00000443204-0.1379298-GBM
ENSG00000237181ENST00000429872RNF123ENSG00000164068ENST00000433785-0.13381-GBM
ENSG00000237181ENST00000429872CMTM4ENSG00000183723ENST00000561680-0.1595198-GBM,KIRC,KIRP
ENSG00000237181ENST00000429872CMTM4ENSG00000183723ENST00000563952-0.1051229-GBM,KIRC,KIRP
ENSG00000237181ENST00000429872NDUFS1ENSG00000023228ENST00000449699-0.211153-KIRC
ENSG00000237181ENST00000429872NDUFS1ENSG00000023228ENST00000432169-0.211153-KIRC
ENSG00000237181ENST00000429872EPB41L5ENSG00000115109ENST00000331393-0.108582-KIRC
ENSG00000237181ENST00000429872KIF2AENSG00000068796ENST00000401507-0.1183455-GBM
ENSG00000237181ENST00000429872KIF2AENSG00000068796ENST00000407818-0.1689318-GBM
ENSG00000237181ENST00000429872KIF2AENSG00000068796ENST00000506857-0.1396281-GBM
ENSG00000237181ENST00000429872ATRNENSG00000088812ENST00000446916-0.157633-GBM
ENSG00000237181ENST00000429872USP32ENSG00000170832ENST00000300896-0.1058132-GBM
ENSG00000237181ENST00000429872USP32ENSG00000170832ENST00000592339-0.1316496-GBM
ENSG00000237181ENST00000429872USP32ENSG00000170832ENST00000593071-0.1316502-GBM
ENSG00000237181ENST00000429872USP32ENSG00000170832ENST00000589552-0.1020446-GBM
ENSG00000237181ENST00000429872USP32ENSG00000170832ENST00000590297-0.1025304-GBM
ENSG00000237181ENST00000429872L2HGDHENSG00000087299ENST00000261699-1.5200441LUSCKIRC,KIRP
ENSG00000237181ENST00000429872L2HGDHENSG00000087299ENST00000555423-0.326013LUSCKIRC,KIRP
ENSG00000237181ENST00000429872L2HGDHENSG00000087299ENST00000555610-0.1077255LUSCKIRC,KIRP
ENSG00000237181ENST00000429872HECTD1ENSG00000092148ENST00000554471-0.1423243-GBM
ENSG00000237181ENST00000429872BCL2L2ENSG00000129473ENST00000556599-0.42393-GBM
ENSG00000237181ENST00000429872MAGI1ENSG00000151276ENST00000460329-0.11691-GBM
ENSG00000237181ENST00000429872MAGI1ENSG00000151276ENST00000497477-0.1766100-GBM
ENSG00000237181ENST00000429872HACD3ENSG00000074696ENST00000565299-0.165776-KIRC,KIRP

Top

lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

Top

lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000237181.1ENST00000429872.1121179544