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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000229180

Summary for GS1-124K5.11

check button Gene summary

Gene informationEnsembl ID

ENSG00000229180

Gene symbol

GS1-124K5.11

Gene name
HGNC
Entrez ID

493754

Gene typelincRNA
Synonyms
UniProtAcc

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Structure and expression level for GS1-124K5.11

check buttonDifferentially expressed gene analysis between cancer and normal samples.
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002291804.762130e-019.441082e-04CHOL1.623712e-03

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lncRNA-Protein interaction for GS1-124K5.11

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000118058KMT2A57.5195.0864Q03164TF,EpiNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000116731PRDM252.9393.5004Q13029TF,EpiPredict
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000104885DOT1L46.5693.6369Q8TEK3TF,EpiNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000154832CXXC139.6990.4896Q9P0U4TF,EpiNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000123636BAZ2B76.2494.3673Q9UIF8TF,EpiNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000025293PHF2073.7394.598Q9BVI0TF,EpiNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000116539ASH1L51.6493.1265Q9NR48TF,EpiNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000124151NCOA331.4390.7013Q9Y6Q9TF,EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000123636BAZ2B76.2494.6692Q9UIF8TF,EpiNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000025293PHF2073.7394.6713Q9BVI0TF,EpiNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000130254SAFB258.792.4903Q14151TF,RBPENCODE
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000257923CUX158.6990.6622P39880TFChIP-seq,catRAPID
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000118058KMT2A57.5195.1791Q03164TF,EpiNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000181827RFX753.1990.2987Q2KHR2TFNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000116731PRDM252.9393.5111Q13029TF,EpiPredict
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000116539ASH1L51.6493.1524Q9NR48TF,EpiNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000104885DOT1L46.5693.8375Q8TEK3TF,EpiNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000167232ZNF9142.4993.6698Q05481TFNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000198521ZNF4339.9590.6072P17038TFNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000154832CXXC139.6990.8215Q9P0U4TF,EpiNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000126464PRR1237.5893.3184Q9ULL5TFNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000126804ZBTB136.6892.3255Q9Y2K1TFNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000147789ZNF733.4290.3198P17097TFNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000198040ZNF8432.191.1552P51523TFNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000124151NCOA331.4390.8326Q9Y6Q9TF,EpiNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000186272ZNF1723.7191.6416P17021TFNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000105708ZNF1418.2490.1033P17017TFNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000197857ZNF4413.2191.3472P15621TFNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000184939ZFP9012.9590.4471Q8TF47TFNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000168661ZNF3012.9190.9634P17039TFNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000256223ZNF107.8790.2643P21506TFNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000196378ZNF344.6691.5754Q8IZ26TFNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000146757ZNF924.1290.4594Q03936TFNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000175395ZNF252.7291.0007P17030TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000013573DDX1160.7692.5943Q96FC9RBPNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000130254SAFB258.792.3195Q14151TF,RBPENCODE
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000004534RBM658.1992.1063P78332RBPHigh-throughput data
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000122965RBM1955.8892.579Q9Y4C8RBPNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000198000NOL852.2492.6789Q76FK4RBPNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000106344RBM2851.4692.5529Q9NW13RBPNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000137776SLTM50.094.2147Q9NWH9RBPENCODE
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000133226SRRM124.3495.1897Q8IYB3RBPNA
ENSG00000229180ENST00000625310GS1-124K5.11ENSG00000167978SRRM216.7296.7708Q9UQ35RBPNA

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lncRNA-DNA interaction for GS1-124K5.11

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
ZNF30,RBM19,NCOA2,ILF3,GLI4,PBX2,RBM39,ZBTB4,IRF3,CIRBP,DDX56,MZF1,MYSM1,NRF1,AKAP8,ZNF2,KAT7,ARID2,ZXDC,SUGP2,DMTF1,ZNF70,BAZ2A,ZNF24,RBM28,ATF6B,TBP,DDX55,KMT2B,STAT2,TET3,NR6A1,ZFP14,RNPC3,ZFP69,SAFB2,THOC1,ZNF25,MNT,CNOT4,SON,ZBED5,CENPT,TTC14,CREB1,RC3H1,SUGP1,ZNF44,ZNF91,SRSF4,RBMX,AGO2,RBM4B,TIGD6,RBM26,CPSF1,RBM14,PURB,ZBTB3,MYEF2,MBD1,IKZF4,PUS7L,ASH1L,MEIS1,DHX34,NFIA,CPSF4,RBM15,SP4,CPSF7,THOC2,CXXC1,ZNF34,THAP6,PATZ1,DDX17,MOV10,SRRM2,RFX7,PRR12,MECP2,PHF1,PURA,ZC3H8,RBM41,HSF4,NOL9,DZIP3,ZFP62,SGSM2,CELF1,SCMH1,ELK4,TIGD1,RBM45,PRDM2,RBM10,DDX51,E2F4,MBD4,AGO3,FOXP1,SRSF2,MBD6,ZGPAT,FIZ1,PBX4,ZMAT1,ZNF83,ZNF3,RFX3,NXF1,ZNF8,ZNF18,NR2C2,STAT6,DDX11,PUS10,RBM6,HMGN3,ZNF14,RFX1,RBM48,GMEB2,NOL3,ZFHX3,XPO1,RBM5,ELF2,SMAD4,ZNF43,ZFP28,ZNF17,SRCAP,DOT1L,ZNF84,DDX42,BAZ2B,RXRB,TRA2A,AHDC1,KMT2A,ZNF69,SRSF7,HINFP,NR2C1,ZFP3,TEP1,SFPQ,TET2,RBM33,NOL8,ZNF10
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for GS1-124K5.11

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000229180ENST00000625310exon_skip_111863chr14:23565815-23565892-15.05-0.2315AP1G2ENST00000308724,ENST00000397120Frame-shift
ENSG00000229180ENST00000625310exon_skip_114365chr14:74290026-74290118-13.03-0.1515ABCD4ENST00000356924Frame-shift
ENSG00000229180ENST00000625310exon_skip_370518chr22:50247691-50247776-12.76-0.1636HDAC10ENST00000216271Frame-shift
ENSG00000229180ENST00000625310exon_skip_66482chr11:126274926-126275021-15.65-0.1841FOXRED1ENST00000263578Frame-shift
ENSG00000229180ENST00000625310exon_skip_74009chr11:64773429-64773505-10.49-0.1665SF1ENST00000377390Frame-shift
ENSG00000229180ENST00000625310exon_skip_319223chr19:43526200-43526349-18.21-0.1282ETHE1ENST00000292147Frame-shift
ENSG00000229180ENST00000625310exon_skip_374375chr3:49675182-49675309-17.41-0.1527APEHENST00000296456Frame-shift
ENSG00000229180ENST00000625310exon_skip_382458chr3:38131595-38131638-10.99-0.7850ACAA1ENST00000333167Frame-shift
ENSG00000229180ENST00000625310exon_skip_499390chr9:127808557-127808705-22.28-0.1921FPGSENST00000373247Frame-shift
ENSG00000229180ENST00000625310exon_skip_111870chr14:23566561-23566686-15.06-0.2215AP1G2ENST00000397120Frame-shift
ENSG00000229180ENST00000625310exon_skip_290158chr17:42953723-42953778-9.06-0.3124AARSD1ENST00000427569Frame-shift
ENSG00000229180ENST00000625310exon_skip_300663chr19:1425877-1425960-14.22-0.3307DAZAP1ENST00000233078Frame-shift
ENSG00000229180ENST00000625310exon_skip_326885chr2:74490024-74490127-14.73-0.1519TTC31ENST00000233623Frame-shift
ENSG00000229180ENST00000625310exon_skip_370525chr22:50250426-50250523-16.29-0.2011HDAC10ENST00000216271Frame-shift
ENSG00000229180ENST00000625310exon_skip_431827chr4:109696409-109696486-8.00-0.1176CASP6ENST00000265164Frame-shift
ENSG00000229180ENST00000449307exon_skip_442657chr5:74730259-74730398-15.88-0.1176GFM2ENST00000296805,ENST00000509430Frame-shift
ENSG00000229180ENST00000449307exon_skip_470226chr7:103307595-103307708-16.18-0.1602PMPCBENST00000249269Frame-shift
ENSG00000229180ENST00000625310exon_skip_511212chrX:71555189-71555385-22.04-0.1344OGTENST00000373719Frame-shift

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for GS1-124K5.11

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA-RBP complex negative regulation
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type
ENSG00000229180ENSG00000004534RBM6exon_skip_114365ENSG00000119688:chr14:74290026-74290118ABCD4ENST00000356924Frame-shiftSTAD,READ,OV,PAAD,THCA
ENSG00000229180ENSG00000004534RBM6exon_skip_370518ENSG00000100429:chr22:50247691-50247776HDAC10ENST00000216271Frame-shiftSARC,UVM,READ,PRAD,PAAD
ENSG00000229180ENSG00000004534RBM6exon_skip_382458ENSG00000060971:chr3:38131595-38131638ACAA1ENST00000333167Frame-shiftSTAD,READ,OV,UCS,PAAD,THCA

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000229180.5ENST00000449307.350141293
ENSG00000229180.5ENST00000625310.116822332739