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Gene: ENSG00000272573 |
Summary for MUSTN1 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000272573 | Gene symbol | MUSTN1 |
| Gene name | musculoskeletal, embryonic nuclear protein 1 | |
| HGNC | 22144 | |
| Entrez ID | 389125 | |
| Gene type | protein_coding | |
| Synonyms | MUSTN1|Mustang | |
| UniProtAcc | Q8IVN3 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
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Structure and expression level for MUSTN1 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
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Sex-biased somatic mutation for MUSTN1 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for MUSTN1 |
| Landscape of DNA methylation across multiple cancer types. |
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| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| THCA | cg21547371 | chr3:52835505 | CGI:chr3:52897210-52897824 | promoter | 7.43e-01 | 6.31e-01 | 3.02e+00 | 2.49e-03 | 6.06e-03 | 1.12e-01 |
| LUSC | cg21547371 | chr3:52835505 | CGI:chr3:52897210-52897824 | promoter | 7.95e-01 | 6.35e-01 | 4.05e+00 | 5.10e-05 | 5.60e-04 | 1.60e-01 |
| BLCA | cg18741586 | chr3:52834983 | CGI:chr3:52897210-52897824 | UTR,promoter,exon,gene body | 6.53e-01 | 5.19e-01 | 4.11e+00 | 4.01e-05 | 2.14e-04 | 1.34e-01 |
| BLCA | cg21547371 | chr3:52835505 | CGI:chr3:52897210-52897824 | promoter | 7.95e-01 | 5.73e-01 | 4.45e+00 | 8.59e-06 | 8.91e-05 | 2.21e-01 |
| CHOL | cg18741586 | chr3:52834983 | CGI:chr3:52897210-52897824 | UTR,promoter,exon,gene body | 6.31e-01 | 3.45e-01 | 3.46e+00 | 5.30e-04 | 8.63e-03 | 2.86e-01 |
| CHOL | cg12941836 | chr3:52835272 | CGI:chr3:52897210-52897824 | promoter | 7.06e-01 | 4.97e-01 | 3.10e+00 | 1.96e-03 | 1.07e-02 | 2.08e-01 |
| CHOL | cg09354317 | chr3:52835291 | CGI:chr3:52897210-52897824 | promoter | 7.06e-01 | 4.77e-01 | 3.24e+00 | 1.18e-03 | 1.07e-02 | 2.29e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg18741586 | chr3:52834983 | CGI:chr3:52897210-52897824 | UTR,promoter,exon,gene body | 6.87e-01 | 5.21e-01 | 1.35e+01 | 1.07e-41 | 1.30e-39 | 1.65e-01 |
| BRCA | cg12941836 | chr3:52835272 | CGI:chr3:52897210-52897824 | promoter | 7.71e-01 | 6.05e-01 | 1.43e+01 | 1.20e-46 | 1.35e-43 | 1.66e-01 |
| BRCA | cg09354317 | chr3:52835291 | CGI:chr3:52897210-52897824 | promoter | 7.56e-01 | 5.71e-01 | 1.43e+01 | 1.09e-46 | 1.28e-43 | 1.85e-01 |
| BRCA | cg21547371 | chr3:52835505 | CGI:chr3:52897210-52897824 | promoter | 8.32e-01 | 6.23e-01 | 1.34e+01 | 3.11e-41 | 3.34e-39 | 2.09e-01 |
| HNSC | cg18741586 | chr3:52834983 | CGI:chr3:52897210-52897824 | UTR,promoter,exon,gene body | 6.49e-01 | 5.27e-01 | 3.39e+00 | 6.91e-04 | 9.05e-03 | 1.21e-01 |
| COAD | cg18741586 | chr3:52834983 | CGI:chr3:52897210-52897824 | UTR,promoter,exon,gene body | 5.71e-01 | 6.72e-01 | -3.97e+00 | 7.16e-05 | 5.50e-04 | -1.01e-01 |
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Exon skipping events with PSI in TCGA for MUSTN1 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
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RNA A-to-I editing events in TCGA for MUSTN1 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for MUSTN1 |
| TFs related to MUSTN1. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| GBM | ASCL1 | MUSTN1 | 4.58e+00 | 9.90e-01 | 3.20e+00 | 4.13e-03 | Male-biased |
| GBM | ASCL2 | MUSTN1 | 4.70e+00 | 9.85e-01 | 3.63e+00 | 1.07e-02 | Male-biased |
| GBM | KLF10 | MUSTN1 | 4.36e+00 | 9.86e-01 | 3.08e+00 | 5.47e-03 | Male-biased |
| GBM | LYL1 | MUSTN1 | 4.51e+00 | 9.84e-01 | 3.41e+00 | 9.56e-03 | Male-biased |
| GBM | NHLH1 | MUSTN1 | 4.94e+00 | 9.93e-01 | 3.51e+00 | 3.54e-03 | Male-biased |
| GBM | NR1H4 | MUSTN1 | 4.69e+00 | 9.93e-01 | 3.17e+00 | 2.68e-03 | Male-biased |
| GBM | SPZ1 | MUSTN1 | 4.70e+00 | 9.88e-01 | 3.49e+00 | 7.18e-03 | Male-biased |
| GBM | TCF12 | MUSTN1 | 4.69e+00 | 9.92e-01 | 3.20e+00 | 3.01e-03 | Male-biased |
| GBM | TFAP2E | MUSTN1 | 4.84e+00 | 9.84e-01 | 3.81e+00 | 1.23e-02 | Male-biased |
| GBM | XPA | MUSTN1 | 4.64e+00 | 9.83e-01 | 3.60e+00 | 1.17e-02 | Male-biased |
| GBM | ZFP69B | MUSTN1 | 4.58e+00 | 9.84e-01 | 3.49e+00 | 1.02e-02 | Male-biased |
| GBM | ZNF19 | MUSTN1 | 4.78e+00 | 9.89e-01 | 3.57e+00 | 7.01e-03 | Male-biased |
| GBM | ZNF223 | MUSTN1 | 4.54e+00 | 9.84e-01 | 3.43e+00 | 9.63e-03 | Male-biased |
| GBM | ZNF28 | MUSTN1 | 4.82e+00 | 9.93e-01 | 3.34e+00 | 3.02e-03 | Male-biased |
| GBM | ZNF300 | MUSTN1 | 4.51e+00 | 9.89e-01 | 3.19e+00 | 4.90e-03 | Male-biased |
| GBM | ZNF460 | MUSTN1 | 4.47e+00 | 9.85e-01 | 3.32e+00 | 8.24e-03 | Male-biased |
| GBM | ZNF563 | MUSTN1 | 4.56e+00 | 9.89e-01 | 3.25e+00 | 5.13e-03 | Male-biased |
| GBM | ZNF573 | MUSTN1 | 4.79e+00 | 9.89e-01 | 3.55e+00 | 6.58e-03 | Male-biased |
| GBM | ZSCAN30 | MUSTN1 | 4.53e+00 | 9.88e-01 | 3.24e+00 | 5.43e-03 | Male-biased |
| MESO | NR1H4 | MUSTN1 | 2.86e+00 | 8.02e-03 | 4.19e+00 | 9.80e-01 | Female-biased |
| MESO | ZNF28 | MUSTN1 | 2.89e+00 | 5.26e-03 | 4.35e+00 | 9.86e-01 | Female-biased |
| MESO | ZNF311 | MUSTN1 | 2.60e+00 | 4.04e-03 | 4.13e+00 | 9.84e-01 | Female-biased |
| MESO | ZNF460 | MUSTN1 | 2.91e+00 | 6.42e-03 | 4.31e+00 | 9.84e-01 | Female-biased |
| SARC | TBR1 | MUSTN1 | 4.74e+00 | 9.92e-01 | 4.00e+00 | 3.45e-03 | Male-biased |
| SARC | TBX18 | MUSTN1 | 4.65e+00 | 9.81e-01 | 4.14e+00 | 1.37e-02 | Male-biased |
| SARC | TBX6 | MUSTN1 | 4.59e+00 | 9.83e-01 | 4.04e+00 | 1.05e-02 | Male-biased |
| SARC | TEAD2 | MUSTN1 | 5.01e+00 | 9.81e-01 | 4.52e+00 | 1.62e-02 | Male-biased |
| SARC | TEAD4 | MUSTN1 | 4.06e+00 | 9.80e-01 | 3.39e+00 | 4.83e-03 | Male-biased |
| SARC | ZNF490 | MUSTN1 | 4.38e+00 | 9.84e-01 | 3.78e+00 | 7.60e-03 | Male-biased |
| MUSTN1 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for MUSTN1 |
| RBPs related to ES in MUSTN1. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| MUSTN1 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of MUSTN1 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
