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Gene: ENSG00000213988 |
Summary for ZNF90 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000213988 | Gene symbol | ZNF90 |
| Gene name | zinc finger protein 90 | |
| HGNC | 13165 | |
| Entrez ID | 7643 | |
| Gene type | protein_coding | |
| Synonyms | ZNF90|HTF9 | |
| UniProtAcc | Q03938 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
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Structure and expression level for ZNF90 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| ZNF90 | 4.43e+02 | 1.34e+00 | 5.11e-01 | 2.62e+00 | 8.77e-03 | 2.13e-02 | BLCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
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Sex-biased somatic mutation for ZNF90 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for ZNF90 |
| Landscape of DNA methylation across multiple cancer types. |
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| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| THCA | cg14766646 | chr19:20076528 | CGI:chr19:20051963-20052298 | promoter | 6.68e-01 | 5.46e-01 | 3.66e+00 | 2.48e-04 | 1.14e-03 | 1.22e-01 |
| LUSC | cg14766646 | chr19:20076528 | CGI:chr19:20051963-20052298 | promoter | 5.87e-01 | 8.10e-01 | -3.90e+00 | 9.43e-05 | 6.81e-04 | -2.23e-01 |
| LUSC | cg03317517 | chr19:20077994 | CGI:chr19:20051963-20052298 | promoter | 4.07e-01 | 1.38e-01 | 2.58e+00 | 9.98e-03 | 1.38e-02 | 2.70e-01 |
| CHOL | cg26265468 | chr19:20078893 | CGI:chr19:20051963-20052298 | promoter,gene body | 2.70e-01 | 1.23e-01 | 2.36e+00 | 1.83e-02 | 2.92e-02 | 1.47e-01 |
| CHOL | cg03317517 | chr19:20077994 | CGI:chr19:20051963-20052298 | promoter | 4.52e-01 | 1.36e-01 | 2.43e+00 | 1.50e-02 | 2.65e-02 | 3.16e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg03317517 | chr19:20077994 | CGI:chr19:20051963-20052298 | promoter | 2.75e-01 | 8.65e-02 | 6.74e+00 | 1.55e-11 | 4.34e-11 | 1.89e-01 |
| LUAD | cg03317517 | chr19:20077994 | CGI:chr19:20051963-20052298 | promoter | 2.79e-01 | 9.20e-02 | 2.03e+00 | 4.23e-02 | 4.42e-02 | 1.87e-01 |
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Exon skipping events with PSI in TCGA for ZNF90 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
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RNA A-to-I editing events in TCGA for ZNF90 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for ZNF90 |
| TFs related to ZNF90. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| BLCA | ASCL1 | ZNF90 | 4.05e+00 | 9.80e-01 | 3.04e+00 | 4.57e-03 | Male-biased |
| BLCA | LYL1 | ZNF90 | 4.13e+00 | 9.82e-01 | 3.15e+00 | 5.13e-03 | Male-biased |
| BLCA | NHLH1 | ZNF90 | 4.41e+00 | 9.89e-01 | 3.27e+00 | 3.10e-03 | Male-biased |
| BLCA | NHLH2 | ZNF90 | 4.34e+00 | 9.86e-01 | 3.34e+00 | 4.81e-03 | Male-biased |
| BLCA | TCF12 | ZNF90 | 4.25e+00 | 9.85e-01 | 3.22e+00 | 4.43e-03 | Male-biased |
| BLCA | TCF3 | ZNF90 | 4.46e+00 | 9.90e-01 | 3.33e+00 | 3.29e-03 | Male-biased |
| BLCA | TFAP4 | ZNF90 | 4.37e+00 | 9.86e-01 | 3.43e+00 | 6.01e-03 | Male-biased |
| BLCA | ZFP69B | ZNF90 | 4.30e+00 | 9.83e-01 | 3.42e+00 | 7.35e-03 | Male-biased |
| BLCA | ZNF329 | ZNF90 | 4.59e+00 | 9.88e-01 | 3.64e+00 | 5.94e-03 | Male-biased |
| BLCA | ZNF335 | ZNF90 | 4.29e+00 | 9.83e-01 | 3.40e+00 | 7.16e-03 | Male-biased |
| BLCA | ZNF530 | ZNF90 | 4.11e+00 | 9.80e-01 | 3.20e+00 | 6.39e-03 | Male-biased |
| BRCA | PRDM6 | ZNF90 | 4.46e+00 | 9.86e-01 | 3.04e+00 | 5.66e-03 | Male-biased |
| BRCA | ZNF182 | ZNF90 | 4.63e+00 | 9.87e-01 | 3.24e+00 | 6.30e-03 | Male-biased |
| BRCA | ZNF22 | ZNF90 | 4.63e+00 | 9.87e-01 | 3.25e+00 | 6.37e-03 | Male-biased |
| BRCA | ZNF225 | ZNF90 | 4.54e+00 | 9.86e-01 | 3.20e+00 | 7.14e-03 | Male-biased |
| BRCA | ZNF235 | ZNF90 | 4.59e+00 | 9.89e-01 | 3.12e+00 | 4.85e-03 | Male-biased |
| BRCA | ZNF287 | ZNF90 | 4.46e+00 | 9.86e-01 | 3.04e+00 | 5.65e-03 | Male-biased |
| BRCA | ZNF418 | ZNF90 | 4.96e+00 | 9.94e-01 | 3.20e+00 | 2.07e-03 | Male-biased |
| BRCA | ZNF487 | ZNF90 | 4.54e+00 | 9.88e-01 | 3.09e+00 | 5.10e-03 | Male-biased |
| BRCA | ZNF879 | ZNF90 | 4.66e+00 | 9.89e-01 | 3.23e+00 | 5.62e-03 | Male-biased |
| DLBC | EN1 | ZNF90 | 5.13e+00 | 9.93e-01 | 4.07e+00 | 4.75e-03 | Male-biased |
| DLBC | FOXP1 | ZNF90 | 4.87e+00 | 9.93e-01 | 3.74e+00 | 3.56e-03 | Male-biased |
| DLBC | HSFY1 | ZNF90 | 5.20e+00 | 9.85e-01 | 4.40e+00 | 1.25e-02 | Male-biased |
| DLBC | HSFY2 | ZNF90 | 5.10e+00 | 9.88e-01 | 4.23e+00 | 9.53e-03 | Male-biased |
| DLBC | MSX1 | ZNF90 | 4.62e+00 | 9.93e-01 | 3.26e+00 | 1.51e-03 | Male-biased |
| DLBC | MSX2 | ZNF90 | 4.57e+00 | 9.92e-01 | 3.21e+00 | 1.48e-03 | Male-biased |
| DLBC | MYNN | ZNF90 | 4.17e+00 | 9.87e-01 | 2.69e+00 | 9.18e-04 | Male-biased |
| DLBC | NHLH1 | ZNF90 | 2.81e+00 | 2.47e-03 | 4.08e+00 | 9.84e-01 | Female-biased |
| DLBC | PRDM1 | ZNF90 | 4.01e+00 | 9.83e-01 | 2.70e+00 | 1.68e-03 | Male-biased |
| DLBC | TCF3 | ZNF90 | 2.81e+00 | 3.08e-03 | 4.02e+00 | 9.82e-01 | Female-biased |
| DLBC | TCF4 | ZNF90 | 4.27e+00 | 9.82e-01 | 3.33e+00 | 7.32e-03 | Male-biased |
| DLBC | TFAP4 | ZNF90 | 3.05e+00 | 5.58e-03 | 4.09e+00 | 9.82e-01 | Female-biased |
| DLBC | ZKSCAN2 | ZNF90 | 4.38e+00 | 9.91e-01 | 2.92e+00 | 1.01e-03 | Male-biased |
| DLBC | ZNF175 | ZNF90 | 4.20e+00 | 9.88e-01 | 2.72e+00 | 9.21e-04 | Male-biased |
| DLBC | ZNF280A | ZNF90 | 4.35e+00 | 9.86e-01 | 3.32e+00 | 5.09e-03 | Male-biased |
| DLBC | ZNF35 | ZNF90 | 4.25e+00 | 9.89e-01 | 2.51e+00 | 3.94e-04 | Male-biased |
| ESCA | ZNF543 | ZNF90 | 2.96e+00 | 4.77e-03 | 3.91e+00 | 9.83e-01 | Female-biased |
| ESCA | ZNF776 | ZNF90 | 3.21e+00 | 9.27e-03 | 4.02e+00 | 9.80e-01 | Female-biased |
| PAAD | MSX1 | ZNF90 | 3.37e+00 | 9.43e-03 | 4.18e+00 | 9.81e-01 | Female-biased |
| PAAD | MSX2 | ZNF90 | 3.31e+00 | 8.70e-03 | 4.13e+00 | 9.80e-01 | Female-biased |
| PAAD | ZKSCAN2 | ZNF90 | 3.14e+00 | 5.05e-03 | 4.07e+00 | 9.83e-01 | Female-biased |
| PAAD | ZNF235 | ZNF90 | 2.71e+00 | 1.48e-03 | 3.87e+00 | 9.82e-01 | Female-biased |
| PAAD | ZNF35 | ZNF90 | 3.07e+00 | 4.79e-03 | 4.01e+00 | 9.82e-01 | Female-biased |
| PAAD | ZNF418 | ZNF90 | 2.08e+00 | 4.77e-05 | 3.88e+00 | 9.84e-01 | Female-biased |
| ZNF90 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for ZNF90 |
| RBPs related to ES in ZNF90. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ZNF90 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of ZNF90 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
