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Gene: ENSG00000166016 |
Summary for ABTB2 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000166016 | Gene symbol | ABTB2 |
| Gene name | ankyrin repeat and BTB domain containing 2 | |
| HGNC | 23842 | |
| Entrez ID | 25841 | |
| Gene type | protein_coding | |
| Synonyms | ABTB2|DKFZP586C1619|BTBD22|ABTB2A | |
| UniProtAcc | Q8N961 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for ABTB2 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| ABTB2 | 6.75e+02 | -1.08e+00 | 3.91e-01 | -2.77e+00 | 5.53e-03 | 3.85e-02 | BRCA |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| ABTB2 | 7.69e+02 | 1.02e+00 | 1.98e-01 | 5.15e+00 | 2.61e-07 | 5.45e-07 | LUSC |
| ABTB2 | 1.56e+03 | -1.13e+00 | 2.00e-01 | -5.63e+00 | 1.80e-08 | 8.48e-08 | KIRP |
| ABTB2 | 7.36e+02 | -1.27e+00 | 4.74e-01 | -2.69e+00 | 7.18e-03 | 1.87e-02 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| ABTB2 | 5.50e+02 | 1.03e+00 | 1.53e-01 | 6.75e+00 | 1.48e-11 | 7.90e-11 | LUAD |
Top |
Sex-biased somatic mutation for ABTB2 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for ABTB2 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg03831465 | chr11:34357250 | CGI:chr11:34356682-34358176 | promoter,exon,CDS,gene body | 5.88e-02 | 1.89e-01 | -1.98e+00 | 4.79e-02 | 4.91e-02 | -1.30e-01 |
| BRCA | cg00508498 | chr11:34357258 | CGI:chr11:34356682-34358176 | promoter,exon,CDS,gene body | 9.18e-02 | 2.49e-01 | -2.80e+00 | 5.09e-03 | 2.05e-02 | -1.57e-01 |
| BRCA | cg20211779 | chr11:34357374 | CGI:chr11:34356682-34358176 | promoter,exon,CDS,gene body | 1.02e-01 | 2.49e-01 | -2.63e+00 | 8.43e-03 | 2.50e-02 | -1.47e-01 |
| BRCA | cg01888411 | chr11:34356746 | CGI:chr11:34356682-34358176 | promoter,exon,CDS,gene body | 1.62e-01 | 3.05e-01 | -2.23e+00 | 2.54e-02 | 3.83e-02 | -1.43e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BLCA | cg20406267 | chr11:34356374 | CGI:chr11:34356682-34358176 | promoter,gene body | 2.21e-01 | 3.75e-01 | -3.92e+00 | 8.96e-05 | 3.70e-04 | -1.54e-01 |
| LIHC | cg02434541 | chr11:34356071 | CGI:chr11:34356682-34358176 | promoter,gene body | 7.51e-01 | 8.68e-01 | -2.80e+00 | 5.18e-03 | 6.81e-03 | -1.17e-01 |
| CHOL | cg20406267 | chr11:34356374 | CGI:chr11:34356682-34358176 | promoter,gene body | 3.04e-01 | 1.02e-01 | 3.46e+00 | 5.30e-04 | 8.63e-03 | 2.02e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg02434541 | chr11:34356071 | CGI:chr11:34356682-34358176 | promoter,gene body | 7.86e-01 | 8.92e-01 | -5.85e+00 | 4.85e-09 | 1.11e-08 | -1.06e-01 |
| HNSC | cg01888411 | chr11:34356746 | CGI:chr11:34356682-34358176 | promoter,exon,CDS,gene body | 2.16e-01 | 7.70e-02 | 2.28e+00 | 2.23e-02 | 2.95e-02 | 1.39e-01 |
| COAD | cg20406267 | chr11:34356374 | CGI:chr11:34356682-34358176 | promoter,gene body | 3.48e-01 | 2.12e-01 | 2.13e+00 | 3.34e-02 | 3.75e-02 | 1.36e-01 |
Top |
Exon skipping events with PSI in TCGA for ABTB2 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for ABTB2 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for ABTB2 |
| TFs related to ABTB2. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ABTB2 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for ABTB2 |
| RBPs related to ES in ABTB2. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ABTB2 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000166016 | MIR100HG,hsa-mir-497,ABTB2 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000166016 | AL162377.1,hsa-mir-497,ABTB2 | Male-specific ceRNA | TCGA-KIRP |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs12270238 | chr11:35306974:A:G | - | 0.120484561691258 | 0.0276406295733689 | HNSC | Female-baised eQTL |
| rs113679719 | chr11:35311308:C:T | - | 0.120484561691258 | 0.0276406295733689 | HNSC | Female-baised eQTL |
| rs12276085 | chr11:35310388:A:G | - | 0.120188376338443 | 0.0289492070710832 | HNSC | Female-baised eQTL |
| rs3915513 | chr11:35313521:G:A | - | 0.10840519956862 | 0.0494616880827648 | HNSC | Female-baised eQTL |
| rs2840072 | chr11:41839376:A:G | - | 0.145756184466324 | 0.0493072921694133 | KIRP | Female-baised eQTL |
| rs4756675 | chr11:41841727:T:A | - | 0.145756184466324 | 0.0493072921694133 | KIRP | Female-baised eQTL |
| rs1484950 | chr11:41843509:C:G | - | 0.145756184466324 | 0.0493072921694133 | KIRP | Female-baised eQTL |
| rs10836346 | chr11:35228271:G:A | - | 0.156251961973448 | 0.0431951272330726 | LUSC | Female-baised eQTL |
| rs4756639 | chr11:41199088:A:G | - | 0.125205383892804 | 0.0479791093525154 | LUSC | Female-baised eQTL |
| rs61882771 | chr11:35231379:C:T | - | 0.151637133096889 | 0.0481829922185875 | LUSC | Female-baised eQTL |
| rs4755638 | chr11:42690773:T:C | - | 0.110664701931755 | 6.9272301230878e-05 | LGG | Female-baised eQTL |
| rs12800689 | chr11:42671579:C:T | - | 0.108151128868278 | 0.000117721100787279 | LGG | Female-baised eQTL |
| rs7111587 | chr11:42674689:G:T | - | 0.108151128868278 | 0.000117721100787279 | LGG | Female-baised eQTL |
| rs35847811 | chr11:42683151:G:C | - | 0.105705410490375 | 0.000230180960043462 | LGG | Female-baised eQTL |
| rs34207097 | chr11:42683476:C:T | - | 0.105227921824907 | 0.000234032793402881 | LGG | Female-baised eQTL |
| rs12273784 | chr11:39932807:G:A | - | 0.141384272599565 | 0.000250596722867625 | LGG | Female-baised eQTL |
| rs72908166 | chr11:32150197:C:T | - | 0.128953465237946 | 0.000441259702876136 | LGG | Female-baised eQTL |
| rs34022357 | chr11:39961903:T:G | - | 0.144625272781976 | 0.00113524804896289 | LGG | Female-baised eQTL |
| rs78954572 | chr11:39924221:A:G | - | 0.144452501891574 | 0.00119167730675462 | LGG | Female-baised eQTL |
| rs7127916 | chr11:42732768:T:C | - | 0.110766113057954 | 0.00147475273457586 | LGG | Female-baised eQTL |
| rs7939649 | chr11:26514954:C:T | - | 0.117259832139872 | 0.00188154553603289 | LGG | Female-baised eQTL |
| rs12797888 | chr11:39958755:T:C | - | 0.139311303658667 | 0.00195174664960531 | LGG | Female-baised eQTL |
| rs71482187 | chr11:39959260:A:G | - | 0.139311303658667 | 0.00195174664960531 | LGG | Female-baised eQTL |
| rs59286398 | chr11:39954869:T:C | - | 0.138672141863799 | 0.00220030567117866 | LGG | Female-baised eQTL |
| rs7481655 | chr11:39944073:C:T | - | 0.138532744740346 | 0.00226918702283076 | LGG | Female-baised eQTL |
| rs72898306 | chr11:39929771:A:T | - | 0.137677558436632 | 0.0025708662043982 | LGG | Female-baised eQTL |
| rs35394863 | chr11:39941859:T:A | - | 0.137677558436632 | 0.0025708662043982 | LGG | Female-baised eQTL |
| rs7483950 | chr11:39946788:C:T | - | 0.137677558436632 | 0.0025708662043982 | LGG | Female-baised eQTL |
| rs34113190 | chr11:39945918:G:A | - | 0.132038829767434 | 0.00474228858902157 | LGG | Female-baised eQTL |
| rs12802744 | chr11:39935233:G:A | - | 0.131600339177065 | 0.0050877479983298 | LGG | Female-baised eQTL |
| rs35483236 | chr11:39931730:C:G | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs12285169 | chr11:39932027:A:C | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs12272219 | chr11:39932258:G:A | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs12272269 | chr11:39932406:G:A | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs12272323 | chr11:39932500:G:A | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs12286737 | chr11:39932623:A:T | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs12286781 | chr11:39932715:A:G | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs12286793 | chr11:39932743:A:C | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs12273770 | chr11:39932744:G:A | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs12273901 | chr11:39933119:C:T | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs12287036 | chr11:39933120:A:G | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs11035612 | chr11:39933907:C:T | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs72898332 | chr11:39934483:C:T | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs11035613 | chr11:39934858:T:C | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs12793467 | chr11:39937393:T:A | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs12793664 | chr11:39937475:T:G | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs12286179 | chr11:39937562:A:C | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs12273091 | chr11:39937634:C:T | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs12273100 | chr11:39937705:C:T | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs35072624 | chr11:39938637:G:C | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs35013809 | chr11:39939369:G:C | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs35670037 | chr11:39939446:T:G | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs59187918 | chr11:39939463:T:C | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs35958665 | chr11:39940592:G:T | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs12279136 | chr11:39941507:C:T | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs7481660 | chr11:39944104:C:T | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs7942812 | chr11:39944502:G:C | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs7943051 | chr11:39944712:G:A | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs12278607 | chr11:39946219:G:A | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs12278569 | chr11:39946325:C:T | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs12291682 | chr11:39946386:A:G | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs9971590 | chr11:39946472:A:G | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs7481283 | chr11:39946737:T:C | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs7483966 | chr11:39946953:A:C | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs7483990 | chr11:39947043:C:T | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs7480392 | chr11:39947396:A:G | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs7480393 | chr11:39947404:A:C | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs7933907 | chr11:39947846:C:T | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs7934059 | chr11:39948089:A:G | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs11035618 | chr11:39948285:A:G | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs11035620 | chr11:39948652:C:T | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs11035621 | chr11:39948656:T:C | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs11035622 | chr11:39948999:A:C | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs11035623 | chr11:39949536:T:G | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs11035624 | chr11:39949550:T:C | - | 0.131381140286938 | 0.00527165355407055 | LGG | Female-baised eQTL |
| rs11035619 | chr11:39948434:G:A | - | 0.13141582392305 | 0.00528045238112495 | LGG | Female-baised eQTL |
| rs12271971 | chr11:39932030:C:A | - | 0.131223319355187 | 0.00544366581930855 | LGG | Female-baised eQTL |
| rs11035625 | chr11:39950069:T:A | - | 0.130933451656965 | 0.00567519371810515 | LGG | Female-baised eQTL |
| rs35586652 | chr11:24581554:G:A | - | 0.0733636152417459 | 0.00821422720775527 | LGG | Female-baised eQTL |
| rs35120388 | chr11:39937042:G:A | - | 0.126413200941778 | 0.00875655092855263 | LGG | Female-baised eQTL |
| rs4468321 | chr11:39933195:G:A | - | 0.1260859812876 | 0.00907502087056781 | LGG | Female-baised eQTL |
| rs12295949 | chr11:39935885:G:T | - | 0.1260859812876 | 0.00907502087056781 | LGG | Female-baised eQTL |
| rs35301356 | chr11:39936911:A:G | - | 0.1260859812876 | 0.00907502087056781 | LGG | Female-baised eQTL |
| rs12791800 | chr11:39937092:G:C | - | 0.1260859812876 | 0.00907502087056781 | LGG | Female-baised eQTL |
| rs34687267 | chr11:39937172:C:T | - | 0.1260859812876 | 0.00907502087056781 | LGG | Female-baised eQTL |
| rs34800685 | chr11:39945663:A:C | - | 0.1260859812876 | 0.00907502087056781 | LGG | Female-baised eQTL |
| rs35390886 | chr11:39945838:G:C | - | 0.1260859812876 | 0.00907502087056781 | LGG | Female-baised eQTL |
| rs67012914 | chr11:39936641:A:G | - | 0.125674008602145 | 0.00968261385649627 | LGG | Female-baised eQTL |
| rs7949104 | chr11:24581029:C:T | - | 0.0727050289937346 | 0.00994892798055644 | LGG | Female-baised eQTL |
| rs1912135 | chr11:24578364:A:G | - | 0.0725816190809723 | 0.010017039295695 | LGG | Female-baised eQTL |
| rs34578313 | chr11:24579949:G:A | - | 0.0725816190809723 | 0.010017039295695 | LGG | Female-baised eQTL |
| rs59194417 | chr11:44265255:C:T | - | 0.140419168127397 | 0.0104853422919201 | LGG | Female-baised eQTL |
| rs12360940 | chr11:24582510:C:G | - | 0.071470044159807 | 0.0127205158257468 | LGG | Female-baised eQTL |
| rs12800717 | chr11:24592353:G:A | - | 0.0707286293524151 | 0.0139312796146776 | LGG | Female-baised eQTL |
| rs11028029 | chr11:24573271:G:A | - | 0.0702969908330373 | 0.0162547146951925 | LGG | Female-baised eQTL |
| rs34355204 | chr11:24575106:C:T | - | 0.0702969908330373 | 0.0162547146951925 | LGG | Female-baised eQTL |
| rs59534867 | chr11:34283575:T:C | gene | 0.0916668053022611 | 0.0293778129669707 | LGG | Female-baised eQTL |
| rs1446672 | chr11:36236520:G:A | - | 0.101696514752969 | 0.0392670900631972 | LGG | Female-baised eQTL |
| rs72914540 | chr11:34285182:G:A | gene | 0.0888413497372249 | 0.0399375296395475 | LGG | Female-baised eQTL |
| rs72640872 | chr11:36750189:T:C | - | 0.119781241493028 | 0.0431313878020549 | LGG | Female-baised eQTL |
| rs111900071 | chr11:36260024:C:G | - | 0.208641909322074 | 0.00645891572774112 | BLCA | Female-baised eQTL |
| rs16929803 | chr11:37029208:C:T | - | 0.170890448059749 | 0.0484929886790598 | BLCA | Female-baised eQTL |
| rs2016270 | chr11:38796788:T:C | - | 0.0782591385910248 | 0.00147789134875886 | COAD | Female-baised eQTL |
| rs7129305 | chr11:38813033:C:T | - | 0.0787932894728179 | 0.0014977283807801 | COAD | Female-baised eQTL |
| rs11034972 | chr11:38838472:T:C | - | 0.0752306682695687 | 0.00264049757755375 | COAD | Female-baised eQTL |
| rs11034967 | chr11:38817839:T:G | - | 0.0741766578170495 | 0.00343842469068506 | COAD | Female-baised eQTL |
| rs12360728 | chr11:38795792:T:C | - | 0.0719539398355482 | 0.00804217135932945 | COAD | Female-baised eQTL |
| rs7938113 | chr11:38809888:A:C | - | 0.0723137460650647 | 0.0082462194490305 | COAD | Female-baised eQTL |
| rs7119942 | chr11:38965682:C:T | - | 0.0669182305275765 | 0.016147342984203 | COAD | Female-baised eQTL |
| rs7119943 | chr11:38965684:C:T | - | 0.0669182305275765 | 0.016147342984203 | COAD | Female-baised eQTL |
| rs1530778 | chr11:26771505:C:T | - | 0.0653087941627246 | 0.0168495174330967 | COAD | Female-baised eQTL |
| rs11034968 | chr11:38817949:A:G | - | 0.0663745243847361 | 0.0200803249637749 | COAD | Female-baised eQTL |
| rs7122010 | chr11:38893861:C:T | - | 0.0663679206555609 | 0.0211462943096753 | COAD | Female-baised eQTL |
| rs1913056 | chr11:38815498:T:C | - | 0.0664643177603333 | 0.0216414182969541 | COAD | Female-baised eQTL |
| rs11034971 | chr11:38829750:C:A | - | 0.0664643177603333 | 0.0216414182969541 | COAD | Female-baised eQTL |
| rs10837056 | chr11:38824965:A:C | - | 0.0664263983399884 | 0.0219033929517029 | COAD | Female-baised eQTL |
| rs10837057 | chr11:38824989:A:G | - | 0.0664263983399884 | 0.0219033929517029 | COAD | Female-baised eQTL |
| rs1913033 | chr11:38848318:T:A | - | 0.0645607222444489 | 0.0266766549546055 | COAD | Female-baised eQTL |
| rs10837052 | chr11:38818291:T:C | - | 0.0649224407306391 | 0.0293737939014875 | COAD | Female-baised eQTL |
| rs11034580 | chr11:38075453:G:A | - | 0.0743926619028836 | 0.0300426070185229 | COAD | Female-baised eQTL |
| rs12790466 | chr11:38849114:A:C | - | 0.0643535091691789 | 0.0309116908331766 | COAD | Female-baised eQTL |
| rs12360613 | chr11:38895751:T:A | - | 0.0630724577403422 | 0.0337304906388323 | COAD | Female-baised eQTL |
| rs7119965 | chr11:38965745:C:A | - | 0.062247576030343 | 0.0357958754620103 | COAD | Female-baised eQTL |
| rs11035022 | chr11:38960666:A:G | - | 0.0619402699548295 | 0.0379654589821498 | COAD | Female-baised eQTL |
| rs10501212 | chr11:38961066:G:A | - | 0.0619402699548295 | 0.0379654589821498 | COAD | Female-baised eQTL |
| rs10837074 | chr11:38945755:T:A | - | 0.0615835068514778 | 0.0389524832601683 | COAD | Female-baised eQTL |
| rs11035000 | chr11:38925323:T:G | - | 0.0620689869868212 | 0.0399779210991994 | COAD | Female-baised eQTL |
| rs12362954 | chr11:38910854:C:A | - | 0.0615843723153401 | 0.0434365142435329 | COAD | Female-baised eQTL |
| rs12365929 | chr11:38910929:A:C | - | 0.0615843723153401 | 0.0434365142435329 | COAD | Female-baised eQTL |
| rs67373894 | chr11:38951495:C:T | - | 0.0609933021436158 | 0.0436409657294305 | COAD | Female-baised eQTL |
| rs11034992 | chr11:38913497:G:A | - | 0.0614674985826276 | 0.044754791853298 | COAD | Female-baised eQTL |
| rs11512257 | chr11:38917589:T:C | - | 0.0614674985826276 | 0.044754791853298 | COAD | Female-baised eQTL |
| rs117868183 | chr11:38918395:T:C | - | 0.0614674985826276 | 0.044754791853298 | COAD | Female-baised eQTL |
| rs67833059 | chr11:38920412:G:A | - | 0.0614674985826276 | 0.044754791853298 | COAD | Female-baised eQTL |
| rs11034995 | chr11:38920811:G:A | - | 0.0614674985826276 | 0.044754791853298 | COAD | Female-baised eQTL |
| rs12363587 | chr11:38927858:C:T | - | 0.0614674985826276 | 0.044754791853298 | COAD | Female-baised eQTL |
| rs4406805 | chr11:38934062:C:T | - | 0.0614674985826276 | 0.044754791853298 | COAD | Female-baised eQTL |
| rs11035009 | chr11:38936948:C:A | - | 0.0614674985826276 | 0.044754791853298 | COAD | Female-baised eQTL |
| rs11035010 | chr11:38939134:C:T | - | 0.0614674985826276 | 0.044754791853298 | COAD | Female-baised eQTL |
| rs2061944 | chr11:38121587:A:T | - | 0.0699078817707074 | 0.0474671209022067 | COAD | Female-baised eQTL |
| rs4586125 | chr11:39653378:A:C | - | 0.0601641533627152 | 0.0493562257357308 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs7928559 | chr11:35780340:G:A | - | 0.138635959967571 | 0.0001800220163055 | SARC | Male-baised eQTL |
| rs78764031 | chr11:42658071:G:A | - | 0.116372342256705 | 0.00267862886376171 | SARC | Male-baised eQTL |
| rs75119942 | chr11:42636950:G:T | - | 0.113301477138495 | 0.00310747950975202 | SARC | Male-baised eQTL |
| rs59230900 | chr11:42651252:T:C | - | 0.113036431027351 | 0.00315555737270707 | SARC | Male-baised eQTL |
| rs112130338 | chr11:42636666:T:C | - | 0.113039313878215 | 0.00320205491936736 | SARC | Male-baised eQTL |
| rs77742871 | chr11:42645299:G:T | - | 0.113638265590139 | 0.00434487939589668 | SARC | Male-baised eQTL |
| rs76788174 | chr11:42647812:G:A | - | 0.113638265590139 | 0.00434487939589668 | SARC | Male-baised eQTL |
| rs75351955 | chr11:42651357:C:T | - | 0.113638265590139 | 0.00434487939589668 | SARC | Male-baised eQTL |
| rs4077252 | chr11:42652949:G:A | - | 0.113638265590139 | 0.00434487939589668 | SARC | Male-baised eQTL |
| rs74544724 | chr11:42643746:G:C | - | 0.107000694039024 | 0.00645127646786496 | SARC | Male-baised eQTL |
| rs75153109 | chr11:39711884:A:C | - | 0.100794484032254 | 0.0105695198199515 | SARC | Male-baised eQTL |
| rs57441289 | chr11:42460050:T:A | - | 0.10003580320797 | 0.0119749450667024 | SARC | Male-baised eQTL |
| rs57555728 | chr11:39718352:G:A | - | 0.0958828463047006 | 0.01805614296873 | SARC | Male-baised eQTL |
| rs57758991 | chr11:39718513:G:C | - | 0.0958828463047006 | 0.01805614296873 | SARC | Male-baised eQTL |
| rs112591883 | chr11:39718574:C:G | - | 0.0958828463047006 | 0.01805614296873 | SARC | Male-baised eQTL |
| rs11036457 | chr11:41559162:A:G | - | 0.108379750822413 | 0.0180726323311167 | SARC | Male-baised eQTL |
| rs113266083 | chr11:41561876:G:C | - | 0.108379750822413 | 0.0180726323311167 | SARC | Male-baised eQTL |
| rs11036462 | chr11:41565814:A:G | - | 0.108314501736426 | 0.0181323528757596 | SARC | Male-baised eQTL |
| rs77100754 | chr11:42639734:G:A | - | 0.0970005482433394 | 0.0191507574206773 | SARC | Male-baised eQTL |
| rs78765253 | chr11:42639876:A:T | - | 0.0970005482433394 | 0.0191507574206773 | SARC | Male-baised eQTL |
| rs78962111 | chr11:42640259:G:A | - | 0.0970005482433394 | 0.0191507574206773 | SARC | Male-baised eQTL |
| rs78574554 | chr11:42640293:G:C | - | 0.0970005482433394 | 0.0191507574206773 | SARC | Male-baised eQTL |
| rs75196608 | chr11:42640316:G:A | - | 0.0970005482433394 | 0.0191507574206773 | SARC | Male-baised eQTL |
| rs4604869 | chr11:42642230:A:G | - | 0.088280961159298 | 0.0364081582184128 | SARC | Male-baised eQTL |
| rs7129198 | chr11:42641851:C:T | - | 0.0860184293419728 | 0.0419624037677718 | SARC | Male-baised eQTL |
| rs12361794 | chr11:35554227:T:C | - | 0.100151284677447 | 0.0371880704609764 | STAD | Male-baised eQTL |
| rs636328 | chr11:35497732:A:G | - | -0.0735234285617638 | 0.0395558509341753 | KIRC | Male-baised eQTL |
| rs10742348 | chr11:35482217:A:G | - | -0.0750598883819372 | 0.0475556815448435 | KIRC | Male-baised eQTL |
| rs11032223 | chr11:33295189:G:C | - | -0.0578297418701857 | 0.0488065104769763 | KIRC | Male-baised eQTL |
| rs7113867 | chr11:33298102:C:G | - | -0.0578297418701857 | 0.0488065104769763 | KIRC | Male-baised eQTL |
| rs9630170 | chr11:33300829:G:A | - | -0.0578297418701857 | 0.0488065104769763 | KIRC | Male-baised eQTL |
| rs6484653 | chr11:33301032:A:G | - | -0.0578297418701857 | 0.0488065104769763 | KIRC | Male-baised eQTL |
| rs56778729 | chr11:33302342:C:T | - | -0.0578297418701857 | 0.0488065104769763 | KIRC | Male-baised eQTL |
| rs9666540 | chr11:33303260:T:G | - | -0.0578297418701857 | 0.0488065104769763 | KIRC | Male-baised eQTL |
| rs2025014 | chr11:33304692:A:G | - | -0.0578297418701857 | 0.0488065104769763 | KIRC | Male-baised eQTL |
| rs10768003 | chr11:33313584:G:T | - | -0.0578297418701857 | 0.0488065104769763 | KIRC | Male-baised eQTL |
| rs11029765 | chr11:26984140:T:A | - | 0.0756889287026557 | 0.0018330360731945 | COAD | Male-baised eQTL |
| rs7117332 | chr11:26947925:T:C | - | 0.0685200483059396 | 0.00863768160232683 | COAD | Male-baised eQTL |
| rs12290211 | chr11:26948859:A:G | - | 0.0679295433885079 | 0.00957634590412638 | COAD | Male-baised eQTL |
| rs12277118 | chr11:26948863:C:T | - | 0.0679295433885079 | 0.00957634590412638 | COAD | Male-baised eQTL |
| rs59415162 | chr11:26971460:A:G | - | 0.0671848149034297 | 0.0108915553209119 | COAD | Male-baised eQTL |
| rs7949760 | chr11:26941756:G:A | - | 0.0678415098439715 | 0.0113058681113386 | COAD | Male-baised eQTL |
| rs986792 | chr11:26942054:A:T | - | 0.0678415098439715 | 0.0113058681113386 | COAD | Male-baised eQTL |
| rs986793 | chr11:26942279:A:G | - | 0.0678415098439715 | 0.0113058681113386 | COAD | Male-baised eQTL |
| rs12279221 | chr11:26941269:T:C | - | 0.0677752684661036 | 0.0115918166910961 | COAD | Male-baised eQTL |
| rs12289852 | chr11:26952237:T:C | - | 0.0669267660810887 | 0.0116868842765212 | COAD | Male-baised eQTL |
| rs7131042 | chr11:26947366:G:A | - | 0.0664167416656779 | 0.0120460485758326 | COAD | Male-baised eQTL |
| rs12576904 | chr11:26978466:A:G | - | 0.0655793354190905 | 0.0132837719936303 | COAD | Male-baised eQTL |
| rs11029763 | chr11:26981681:T:C | - | 0.0655793354190905 | 0.0132837719936303 | COAD | Male-baised eQTL |
| rs10835089 | chr11:26981870:T:G | - | 0.0655793354190905 | 0.0132837719936303 | COAD | Male-baised eQTL |
| rs4922778 | chr11:26942765:C:G | - | 0.0668616022239288 | 0.0133999275432485 | COAD | Male-baised eQTL |
| rs4922779 | chr11:26943181:T:C | - | 0.0668616022239288 | 0.0133999275432485 | COAD | Male-baised eQTL |
| rs7122421 | chr11:26943589:T:C | - | 0.0668616022239288 | 0.0133999275432485 | COAD | Male-baised eQTL |
| rs7940358 | chr11:26979501:G:A | - | 0.0655014521114143 | 0.0136098691143451 | COAD | Male-baised eQTL |
| rs7105234 | chr11:41250400:G:A | - | -0.0485100207545991 | 0.0160109877611424 | COAD | Male-baised eQTL |
| rs7110466 | chr11:26944491:A:T | - | 0.0656275503041177 | 0.0165470485510214 | COAD | Male-baised eQTL |
| rs7110575 | chr11:26944497:C:G | - | 0.0656275503041177 | 0.0165470485510214 | COAD | Male-baised eQTL |
| rs7110482 | chr11:26944533:A:G | - | 0.0656275503041177 | 0.0165470485510214 | COAD | Male-baised eQTL |
| rs7128480 | chr11:26962812:T:C | - | 0.0835824315098034 | 0.0176327328503683 | COAD | Male-baised eQTL |
| rs12286947 | chr11:26964559:C:T | - | 0.0835824315098034 | 0.0176327328503683 | COAD | Male-baised eQTL |
| rs12274052 | chr11:26965151:A:G | - | 0.0835824315098034 | 0.0176327328503683 | COAD | Male-baised eQTL |
| rs1992677 | chr11:26945373:A:G | - | 0.0642321599185347 | 0.0218196211920891 | COAD | Male-baised eQTL |
| rs12271524 | chr11:26945868:G:A | - | 0.0642321599185347 | 0.0218196211920891 | COAD | Male-baised eQTL |
| rs7108314 | chr11:26989500:G:A | - | 0.0629320253399729 | 0.0233123606513034 | COAD | Male-baised eQTL |
| rs11029757 | chr11:26960656:T:C | - | 0.0744419404057607 | 0.0277085661467679 | COAD | Male-baised eQTL |
| rs7111891 | chr11:26962518:A:G | - | 0.0744419404057607 | 0.0277085661467679 | COAD | Male-baised eQTL |
| rs1445327 | chr11:26985566:T:G | - | 0.0614817951525532 | 0.0299165776071306 | COAD | Male-baised eQTL |
| rs12287195 | chr11:26985991:T:C | - | 0.060969591656292 | 0.0350220393154791 | COAD | Male-baised eQTL |
| rs12419641 | chr11:26987801:G:A | - | 0.0592601160874252 | 0.039004475841512 | COAD | Male-baised eQTL |
| rs111349994 | chr11:26940974:C:T | - | 0.088177500374272 | 0.0392050323873942 | COAD | Male-baised eQTL |
| rs59417854 | chr11:26941531:A:G | - | 0.088177500374272 | 0.0392050323873942 | COAD | Male-baised eQTL |
| rs115691349 | chr11:26982269:G:A | - | 0.0779834814657351 | 0.0395296877782711 | COAD | Male-baised eQTL |
| rs2957594 | chr11:38015291:G:T | - | 0.106767147704243 | 0.0449988436068381 | COAD | Male-baised eQTL |
| rs7107282 | chr11:26944204:G:C | - | 0.0854878907643405 | 0.0465628327754954 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000166016 |
| CpG Site: cg08663298 | |
| Position to Gene: gene | |
| Male Effect: -0.419872093851242 | |
| Female Effect: - | |
 | Gene ID: ENSG00000166016 |
| CpG Site: cg04954111 | |
| Position to Gene: gene | |
| Male Effect: -0.419872093851242 | |
| Female Effect: - | |
 | Gene ID: ENSG00000166016 |
| CpG Site: cg00534343 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.405591200976682 | |
 | Gene ID: ENSG00000166016 |
| CpG Site: cg08202743 | |
| Position to Gene: gene,exon,CDS | |
| Male Effect: - | |
| Female Effect: -0.405591200976682 | |
 | Gene ID: ENSG00000166016 |
| CpG Site: cg02697979 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.405591200976682 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg08663298 | chr11:34328893 | gene | -0.419872093851242 | 2.94966523070889e-09 | -0.4577804440086072 | 8.342658558541666e-12 | KIRP |
| cg04954111 | chr11:34342239 | gene | -0.419872093851242 | 2.94966523070889e-09 | -0.4577804440086072 | 8.342658558541666e-12 | KIRP |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg00534343 | chr11:34160788 | gene | -0.405591200976682 | 2.41474188901713e-05 | -0.39296391174546497 | 5.293510023746295e-08 | SKCM |
| cg08202743 | chr11:34161023 | gene,exon,CDS | -0.405591200976682 | 2.41474188901713e-05 | -0.39296391174546497 | 5.293510023746295e-08 | SKCM |
| cg02697979 | chr11:34243814 | gene | -0.405591200976682 | 2.41474188901713e-05 | -0.39296391174546497 | 5.293510023746295e-08 | SKCM |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of ABTB2 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
