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Gene: ENSG00000153132 |
Summary for CLGN |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000153132 | Gene symbol | CLGN |
| Gene name | calmegin | |
| HGNC | 2060 | |
| Entrez ID | 1047 | |
| Gene type | protein_coding | |
| Synonyms | CLGN| | |
| UniProtAcc | O14967 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for CLGN |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| CLGN | 3.10e+02 | -1.20e+00 | 2.66e-01 | -4.51e+00 | 6.58e-06 | 2.32e-04 | SARC |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| CLGN | 2.00e+02 | 2.33e+00 | 2.96e-01 | 7.88e+00 | 3.20e-15 | 1.17e-14 | KIRC |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| CLGN | 1.15e+03 | 2.61e+00 | 1.79e-01 | 1.46e+01 | 2.84e-48 | 2.72e-47 | BRCA |
Top |
Sex-biased somatic mutation for CLGN |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for CLGN |
| Landscape of DNA methylation across multiple cancer types. |
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| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| DLBC | cg03710295 | chr4:140427895 | CGI:chr4:140426888-140427803 | UTR,promoter,exon,gene body | 1.56e-01 | 2.61e-01 | -3.43e+00 | 5.93e-04 | 2.26e-03 | -1.05e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUAD | cg05373723 | chr4:140426839 | CGI:chr4:140426888-140427803 | promoter,gene body | 2.44e-01 | 1.41e-01 | 2.34e+00 | 1.92e-02 | 2.51e-02 | 1.03e-01 |
| HNSC | cg11539424 | chr4:140427708 | CGI:chr4:140426888-140427803 | UTR,promoter,exon,gene body | 1.70e-01 | 2.18e-02 | 2.15e+00 | 3.16e-02 | 3.67e-02 | 1.49e-01 |
| HNSC | cg17902573 | chr4:140427013 | CGI:chr4:140426888-140427803 | promoter,gene body | 1.70e-01 | 5.30e-02 | 2.12e+00 | 3.44e-02 | 3.88e-02 | 1.17e-01 |
| HNSC | cg08821557 | chr4:140427532 | CGI:chr4:140426888-140427803 | promoter,gene body | 1.50e-01 | 3.50e-02 | 2.36e+00 | 1.81e-02 | 2.60e-02 | 1.15e-01 |
| HNSC | cg08129449 | chr4:140427878 | CGI:chr4:140426888-140427803 | UTR,promoter,exon,gene body | 1.55e-01 | 5.32e-02 | 2.38e+00 | 1.75e-02 | 2.55e-02 | 1.01e-01 |
| COAD | cg08821557 | chr4:140427532 | CGI:chr4:140426888-140427803 | promoter,gene body | 1.46e-01 | 3.22e-02 | 2.64e+00 | 8.37e-03 | 1.38e-02 | 1.14e-01 |
| COAD | cg01725318 | chr4:140427583 | CGI:chr4:140426888-140427803 | UTR,promoter,exon,gene body | 1.66e-01 | 3.55e-02 | 1.99e+00 | 4.66e-02 | 4.75e-02 | 1.30e-01 |
| COAD | cg03710295 | chr4:140427895 | CGI:chr4:140426888-140427803 | UTR,promoter,exon,gene body | 2.28e-01 | 1.19e-01 | 2.02e+00 | 4.32e-02 | 4.49e-02 | 1.09e-01 |
Top |
Exon skipping events with PSI in TCGA for CLGN |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
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| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for CLGN |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for CLGN |
| TFs related to CLGN. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ACC | FOXR2 | CLGN | 3.38e+00 | 8.95e-03 | 4.25e+00 | 9.83e-01 | Female-biased |
| ACC | ZNF334 | CLGN | 3.48e+00 | 1.16e-02 | 4.27e+00 | 9.81e-01 | Female-biased |
| ACC | ZNF418 | CLGN | 3.15e+00 | 7.43e-03 | 4.05e+00 | 9.82e-01 | Female-biased |
| BLCA | CTCFL | CLGN | 3.07e+00 | 2.67e-03 | 4.25e+00 | 9.86e-01 | Female-biased |
| BLCA | FOXD3 | CLGN | 4.33e+00 | 9.86e-01 | 3.34e+00 | 5.14e-03 | Male-biased |
| BLCA | FOXR2 | CLGN | 4.17e+00 | 9.85e-01 | 2.99e+00 | 2.66e-03 | Male-biased |
| BLCA | INSM1 | CLGN | 3.27e+00 | 1.79e-03 | 4.55e+00 | 9.91e-01 | Female-biased |
| BLCA | MBD2 | CLGN | 3.93e+00 | 1.37e-02 | 4.71e+00 | 9.81e-01 | Female-biased |
| BLCA | ZIC4 | CLGN | 3.45e+00 | 2.82e-03 | 4.62e+00 | 9.91e-01 | Female-biased |
| BLCA | ZNF300 | CLGN | 3.44e+00 | 2.22e-03 | 4.67e+00 | 9.92e-01 | Female-biased |
| BLCA | ZNF322 | CLGN | 2.96e+00 | 1.82e-03 | 4.23e+00 | 9.87e-01 | Female-biased |
| BLCA | ZNF334 | CLGN | 4.44e+00 | 9.91e-01 | 3.11e+00 | 1.69e-03 | Male-biased |
| BLCA | ZNF460 | CLGN | 3.84e+00 | 4.98e-03 | 4.87e+00 | 9.91e-01 | Female-biased |
| BLCA | ZNF483 | CLGN | 3.44e+00 | 7.43e-03 | 4.37e+00 | 9.83e-01 | Female-biased |
| BLCA | ZNF534 | CLGN | 3.63e+00 | 5.60e-03 | 4.63e+00 | 9.88e-01 | Female-biased |
| BLCA | ZNF555 | CLGN | 3.48e+00 | 5.44e-03 | 4.48e+00 | 9.87e-01 | Female-biased |
| BLCA | ZNF587 | CLGN | 3.55e+00 | 6.57e-03 | 4.51e+00 | 9.86e-01 | Female-biased |
| BLCA | ZNF707 | CLGN | 3.35e+00 | 1.52e-03 | 4.67e+00 | 9.93e-01 | Female-biased |
| BRCA | CTCFL | CLGN | 2.15e+00 | 5.27e-04 | 4.28e+00 | 9.85e-01 | Female-biased |
| BRCA | DNMT1 | CLGN | 2.38e+00 | 1.57e-03 | 4.17e+00 | 9.81e-01 | Female-biased |
| BRCA | FOXR2 | CLGN | 4.47e+00 | 9.86e-01 | 3.10e+00 | 6.36e-03 | Male-biased |
| BRCA | INSM1 | CLGN | 2.41e+00 | 6.29e-04 | 4.49e+00 | 9.89e-01 | Female-biased |
| BRCA | MBD2 | CLGN | 2.75e+00 | 1.32e-03 | 4.61e+00 | 9.91e-01 | Female-biased |
| BRCA | TCFL5 | CLGN | 3.07e+00 | 5.45e-03 | 4.47e+00 | 9.84e-01 | Female-biased |
| BRCA | ZIC4 | CLGN | 2.64e+00 | 1.08e-03 | 4.55e+00 | 9.90e-01 | Female-biased |
| BRCA | ZNF100 | CLGN | 2.67e+00 | 2.90e-03 | 4.26e+00 | 9.82e-01 | Female-biased |
| BRCA | ZNF300 | CLGN | 2.11e+00 | 3.34e-04 | 4.37e+00 | 9.87e-01 | Female-biased |
| BRCA | ZNF311 | CLGN | 2.32e+00 | 1.11e-03 | 4.23e+00 | 9.83e-01 | Female-biased |
| BRCA | ZNF322 | CLGN | 2.26e+00 | 7.50e-04 | 4.28e+00 | 9.85e-01 | Female-biased |
| BRCA | ZNF334 | CLGN | 4.70e+00 | 9.87e-01 | 3.37e+00 | 7.54e-03 | Male-biased |
| BRCA | ZNF418 | CLGN | 4.51e+00 | 9.93e-01 | 2.05e+00 | 2.19e-04 | Male-biased |
| BRCA | ZNF460 | CLGN | 2.63e+00 | 7.32e-04 | 4.67e+00 | 9.92e-01 | Female-biased |
| BRCA | ZNF483 | CLGN | 2.62e+00 | 1.16e-03 | 4.51e+00 | 9.89e-01 | Female-biased |
| BRCA | ZNF534 | CLGN | 2.60e+00 | 6.78e-04 | 4.66e+00 | 9.92e-01 | Female-biased |
| BRCA | ZNF555 | CLGN | 2.60e+00 | 8.33e-04 | 4.60e+00 | 9.91e-01 | Female-biased |
| BRCA | ZNF587 | CLGN | 2.75e+00 | 1.26e-03 | 4.63e+00 | 9.91e-01 | Female-biased |
| BRCA | ZNF704 | CLGN | 3.40e+00 | 5.67e-03 | 4.79e+00 | 9.88e-01 | Female-biased |
| BRCA | ZNF707 | CLGN | 2.49e+00 | 9.22e-04 | 4.45e+00 | 9.88e-01 | Female-biased |
| BRCA | ZNF768 | CLGN | 2.38e+00 | 1.32e-03 | 4.23e+00 | 9.83e-01 | Female-biased |
| BRCA | ZNF879 | CLGN | 4.27e+00 | 9.88e-01 | 2.36e+00 | 1.28e-03 | Male-biased |
| CHOL | CTCFL | CLGN | 2.74e+00 | 1.26e-03 | 4.16e+00 | 9.89e-01 | Female-biased |
| CHOL | E2F6 | CLGN | 3.19e+00 | 8.73e-03 | 4.15e+00 | 9.81e-01 | Female-biased |
| CHOL | INSM1 | CLGN | 2.60e+00 | 2.11e-03 | 3.91e+00 | 9.83e-01 | Female-biased |
| CHOL | KLF11 | CLGN | 2.53e+00 | 1.93e-03 | 3.85e+00 | 9.82e-01 | Female-biased |
| CHOL | ZNF100 | CLGN | 2.94e+00 | 3.54e-03 | 4.13e+00 | 9.86e-01 | Female-biased |
| CHOL | ZNF180 | CLGN | 2.97e+00 | 5.31e-03 | 4.05e+00 | 9.83e-01 | Female-biased |
| CHOL | ZNF283 | CLGN | 2.87e+00 | 1.90e-03 | 4.21e+00 | 9.89e-01 | Female-biased |
| CHOL | ZNF30 | CLGN | 2.94e+00 | 4.80e-03 | 4.04e+00 | 9.84e-01 | Female-biased |
| CHOL | ZNF300 | CLGN | 2.41e+00 | 8.57e-04 | 3.92e+00 | 9.85e-01 | Female-biased |
| CHOL | ZNF311 | CLGN | 2.93e+00 | 2.78e-03 | 4.18e+00 | 9.88e-01 | Female-biased |
| CHOL | ZNF322 | CLGN | 3.04e+00 | 7.76e-03 | 4.03e+00 | 9.80e-01 | Female-biased |
| CHOL | ZNF418 | CLGN | 3.76e+00 | 9.81e-01 | 2.36e+00 | 1.61e-03 | Male-biased |
| CHOL | ZNF44 | CLGN | 2.90e+00 | 4.62e-03 | 4.01e+00 | 9.83e-01 | Female-biased |
| CHOL | ZNF460 | CLGN | 2.88e+00 | 1.49e-03 | 4.27e+00 | 9.90e-01 | Female-biased |
| CHOL | ZNF484 | CLGN | 2.48e+00 | 9.30e-04 | 3.97e+00 | 9.86e-01 | Female-biased |
| CHOL | ZNF529 | CLGN | 2.63e+00 | 2.27e-03 | 3.91e+00 | 9.83e-01 | Female-biased |
| CHOL | ZNF534 | CLGN | 2.72e+00 | 2.15e-03 | 4.03e+00 | 9.86e-01 | Female-biased |
| CHOL | ZNF548 | CLGN | 2.84e+00 | 1.19e-03 | 4.29e+00 | 9.91e-01 | Female-biased |
| CHOL | ZNF555 | CLGN | 3.06e+00 | 5.50e-03 | 4.13e+00 | 9.84e-01 | Female-biased |
| CHOL | ZNF707 | CLGN | 3.01e+00 | 3.77e-03 | 4.18e+00 | 9.87e-01 | Female-biased |
| CHOL | ZNF792 | CLGN | 2.97e+00 | 4.12e-03 | 4.12e+00 | 9.86e-01 | Female-biased |
| CHOL | ZNF93 | CLGN | 2.82e+00 | 3.04e-03 | 4.04e+00 | 9.85e-01 | Female-biased |
| DLBC | CEBPB | CLGN | 1.10e+01 | 9.84e-01 | 1.02e+01 | 1.57e-02 | Male-biased |
| DLBC | CEBPD | CLGN | 1.06e+01 | 9.86e-01 | 9.84e+00 | 1.39e-02 | Male-biased |
| DLBC | CEBPE | CLGN | 1.09e+01 | 9.85e-01 | 1.02e+01 | 1.46e-02 | Male-biased |
| DLBC | CEBPG | CLGN | 1.08e+01 | 9.87e-01 | 9.98e+00 | 1.34e-02 | Male-biased |
| ESCA | NRF1 | CLGN | 4.45e+00 | 9.92e-01 | 3.48e+00 | 2.42e-03 | Male-biased |
| ESCA | ZNF182 | CLGN | 4.18e+00 | 9.84e-01 | 3.41e+00 | 7.21e-03 | Male-biased |
| ESCA | ZNF22 | CLGN | 4.25e+00 | 9.84e-01 | 3.50e+00 | 8.15e-03 | Male-biased |
| ESCA | ZNF225 | CLGN | 4.31e+00 | 9.81e-01 | 3.62e+00 | 1.18e-02 | Male-biased |
| ESCA | ZNF384 | CLGN | 4.20e+00 | 9.83e-01 | 3.46e+00 | 8.61e-03 | Male-biased |
| ESCA | ZNF613 | CLGN | 4.24e+00 | 9.84e-01 | 3.48e+00 | 8.06e-03 | Male-biased |
| GBM | FOXR2 | CLGN | 4.38e+00 | 9.80e-01 | 3.33e+00 | 1.14e-02 | Male-biased |
| GBM | MBD2 | CLGN | 3.10e+00 | 9.02e-03 | 4.19e+00 | 9.81e-01 | Female-biased |
| GBM | ZIC4 | CLGN | 2.79e+00 | 4.21e-03 | 4.17e+00 | 9.85e-01 | Female-biased |
| GBM | ZNF300 | CLGN | 2.30e+00 | 2.11e-03 | 3.93e+00 | 9.81e-01 | Female-biased |
| GBM | ZNF334 | CLGN | 4.53e+00 | 9.81e-01 | 3.50e+00 | 1.20e-02 | Male-biased |
| GBM | ZNF460 | CLGN | 3.07e+00 | 5.22e-03 | 4.38e+00 | 9.88e-01 | Female-biased |
| GBM | ZNF534 | CLGN | 2.71e+00 | 4.91e-03 | 4.03e+00 | 9.81e-01 | Female-biased |
| GBM | ZNF555 | CLGN | 2.69e+00 | 3.64e-03 | 4.13e+00 | 9.85e-01 | Female-biased |
| GBM | ZNF587 | CLGN | 3.07e+00 | 8.10e-03 | 4.20e+00 | 9.82e-01 | Female-biased |
| LGG | DNMT1 | CLGN | 3.23e+00 | 7.12e-04 | 4.24e+00 | 9.87e-01 | Female-biased |
| LGG | FOXD3 | CLGN | 4.27e+00 | 9.82e-01 | 3.74e+00 | 7.01e-03 | Male-biased |
| LGG | FOXR2 | CLGN | 4.32e+00 | 9.85e-01 | 3.69e+00 | 4.21e-03 | Male-biased |
| LGG | MBD2 | CLGN | 3.32e+00 | 1.40e-03 | 4.19e+00 | 9.85e-01 | Female-biased |
| LGG | TCFL5 | CLGN | 3.74e+00 | 3.97e-03 | 4.41e+00 | 9.87e-01 | Female-biased |
| LGG | ZNF100 | CLGN | 3.25e+00 | 8.93e-04 | 4.21e+00 | 9.86e-01 | Female-biased |
| LGG | ZNF30 | CLGN | 3.06e+00 | 7.98e-04 | 4.04e+00 | 9.82e-01 | Female-biased |
| LGG | ZNF311 | CLGN | 3.01e+00 | 6.09e-04 | 4.06e+00 | 9.83e-01 | Female-biased |
| LGG | ZNF334 | CLGN | 4.50e+00 | 9.88e-01 | 3.90e+00 | 4.73e-03 | Male-biased |
| LGG | ZNF418 | CLGN | 4.31e+00 | 9.88e-01 | 3.53e+00 | 1.86e-03 | Male-biased |
| LGG | ZNF460 | CLGN | 3.23e+00 | 1.22e-03 | 4.12e+00 | 9.84e-01 | Female-biased |
| LGG | ZNF704 | CLGN | 3.71e+00 | 7.88e-03 | 4.25e+00 | 9.80e-01 | Female-biased |
| PAAD | CTCFL | CLGN | 2.74e+00 | 2.11e-03 | 3.83e+00 | 9.80e-01 | Female-biased |
| PAAD | FOXD3 | CLGN | 4.51e+00 | 9.89e-01 | 3.52e+00 | 4.62e-03 | Male-biased |
| PAAD | FOXR2 | CLGN | 4.17e+00 | 9.87e-01 | 2.95e+00 | 1.35e-03 | Male-biased |
| PAAD | INSM1 | CLGN | 2.86e+00 | 2.32e-03 | 3.94e+00 | 9.83e-01 | Female-biased |
| PAAD | MBD2 | CLGN | 3.53e+00 | 7.61e-03 | 4.39e+00 | 9.85e-01 | Female-biased |
| PAAD | ZIC4 | CLGN | 3.27e+00 | 1.85e-03 | 4.40e+00 | 9.91e-01 | Female-biased |
| PAAD | ZNF300 | CLGN | 2.76e+00 | 1.47e-03 | 3.93e+00 | 9.84e-01 | Female-biased |
| PAAD | ZNF322 | CLGN | 2.85e+00 | 3.16e-03 | 3.87e+00 | 9.80e-01 | Female-biased |
| PAAD | ZNF334 | CLGN | 4.28e+00 | 9.90e-01 | 3.00e+00 | 9.59e-04 | Male-biased |
| PAAD | ZNF460 | CLGN | 3.30e+00 | 3.06e-03 | 4.34e+00 | 9.89e-01 | Female-biased |
| PAAD | ZNF534 | CLGN | 3.09e+00 | 4.13e-03 | 4.06e+00 | 9.84e-01 | Female-biased |
| PAAD | ZNF555 | CLGN | 3.26e+00 | 5.03e-03 | 4.19e+00 | 9.85e-01 | Female-biased |
| PAAD | ZNF587 | CLGN | 3.39e+00 | 3.89e-03 | 4.38e+00 | 9.89e-01 | Female-biased |
| PAAD | ZNF707 | CLGN | 3.09e+00 | 2.77e-03 | 4.14e+00 | 9.87e-01 | Female-biased |
| PCPG | DNMT1 | CLGN | 3.44e+00 | 8.04e-03 | 4.29e+00 | 9.83e-01 | Female-biased |
| SARC | FOXR2 | CLGN | 3.97e+00 | 6.70e-03 | 4.69e+00 | 9.89e-01 | Female-biased |
| SARC | INSM1 | CLGN | 4.14e+00 | 9.86e-01 | 3.24e+00 | 1.39e-03 | Male-biased |
| SARC | MBD2 | CLGN | 4.68e+00 | 9.85e-01 | 4.12e+00 | 9.51e-03 | Male-biased |
| SARC | ZIC4 | CLGN | 4.29e+00 | 9.87e-01 | 3.53e+00 | 2.87e-03 | Male-biased |
| SARC | ZNF300 | CLGN | 4.11e+00 | 9.85e-01 | 3.13e+00 | 8.91e-04 | Male-biased |
| SARC | ZNF334 | CLGN | 4.03e+00 | 4.96e-03 | 4.80e+00 | 9.91e-01 | Female-biased |
| SARC | ZNF418 | CLGN | 2.83e+00 | 2.18e-04 | 4.19e+00 | 9.89e-01 | Female-biased |
| SARC | ZNF460 | CLGN | 4.73e+00 | 9.93e-01 | 3.90e+00 | 2.11e-03 | Male-biased |
| SARC | ZNF483 | CLGN | 4.11e+00 | 9.82e-01 | 3.43e+00 | 4.60e-03 | Male-biased |
| SARC | ZNF484 | CLGN | 4.01e+00 | 9.82e-01 | 3.20e+00 | 2.23e-03 | Male-biased |
| SARC | ZNF534 | CLGN | 4.54e+00 | 9.91e-01 | 3.70e+00 | 1.91e-03 | Male-biased |
| SARC | ZNF555 | CLGN | 4.23e+00 | 9.82e-01 | 3.60e+00 | 6.25e-03 | Male-biased |
| SARC | ZNF587 | CLGN | 4.17e+00 | 9.82e-01 | 3.53e+00 | 5.96e-03 | Male-biased |
| SARC | ZNF707 | CLGN | 4.28e+00 | 9.89e-01 | 3.32e+00 | 9.94e-04 | Male-biased |
| SARC | ZNF791 | CLGN | 4.39e+00 | 9.82e-01 | 3.81e+00 | 8.82e-03 | Male-biased |
| SARC | ZNF879 | CLGN | 2.74e+00 | 6.68e-04 | 3.88e+00 | 9.81e-01 | Female-biased |
| THYM | FOXD3 | CLGN | 3.54e+00 | 1.59e-03 | 4.69e+00 | 9.92e-01 | Female-biased |
| THYM | FOXR2 | CLGN | 3.41e+00 | 6.39e-04 | 4.79e+00 | 9.94e-01 | Female-biased |
| THYM | IRX2 | CLGN | 5.11e+00 | 1.54e-02 | 5.70e+00 | 9.83e-01 | Female-biased |
| THYM | POU5F1B | CLGN | 4.08e+00 | 3.20e-03 | 5.06e+00 | 9.93e-01 | Female-biased |
| THYM | PRDM6 | CLGN | 3.47e+00 | 7.48e-03 | 4.23e+00 | 9.80e-01 | Female-biased |
| THYM | ZNF225 | CLGN | 3.49e+00 | 4.27e-03 | 4.39e+00 | 9.86e-01 | Female-biased |
| THYM | ZNF334 | CLGN | 3.44e+00 | 3.28e-04 | 4.99e+00 | 9.96e-01 | Female-biased |
| THYM | ZNF337 | CLGN | 4.73e+00 | 1.18e-02 | 5.38e+00 | 9.86e-01 | Female-biased |
| THYM | ZNF384 | CLGN | 3.58e+00 | 7.59e-03 | 4.34e+00 | 9.82e-01 | Female-biased |
| THYM | ZNF418 | CLGN | 3.39e+00 | 1.62e-04 | 5.14e+00 | 9.97e-01 | Female-biased |
| THYM | ZNF613 | CLGN | 3.63e+00 | 8.53e-03 | 4.36e+00 | 9.81e-01 | Female-biased |
| THYM | ZNF879 | CLGN | 3.36e+00 | 6.34e-04 | 4.74e+00 | 9.94e-01 | Female-biased |
| CLGN related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for CLGN |
| RBPs related to ES in CLGN. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| CLGN related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs9986099 | chr4:137189324:T:C | - | 0.161625461238583 | 0.00161849654659625 | KIRP | Female-baised eQTL |
| rs7660195 | chr4:137190614:C:T | - | 0.161625461238583 | 0.00161849654659625 | KIRP | Female-baised eQTL |
| rs10020833 | chr4:147443367:A:C | - | 0.219122514253505 | 0.00529755953233575 | KIRP | Female-baised eQTL |
| rs28484901 | chr4:147445345:A:C | - | 0.219122514253505 | 0.00529755953233575 | KIRP | Female-baised eQTL |
| rs28631753 | chr4:147445346:G:T | - | 0.219122514253505 | 0.00529755953233575 | KIRP | Female-baised eQTL |
| rs6839545 | chr4:137657307:G:C | - | 0.149526857101893 | 0.00586856189245393 | KIRP | Female-baised eQTL |
| rs10013038 | chr4:147854986:C:T | - | -0.157648908845175 | 0.00613739856467603 | KIRP | Female-baised eQTL |
| rs7663712 | chr4:143339964:A:G | - | 0.177472192709952 | 0.0313665992197496 | KIRP | Female-baised eQTL |
| rs3775242 | chr4:139691952:G:A | - | 0.132599671212643 | 0.0416574139713497 | KIRP | Female-baised eQTL |
| rs72939349 | chr4:133649996:G:A | - | 0.160639681322499 | 0.0421610520287067 | KIRP | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs4412042 | chr4:134520914:T:A | - | -0.137288699233635 | 0.000555867022299636 | PAAD | Male-baised eQTL |
| rs4241952 | chr4:134518751:G:T | - | -0.131616161759975 | 0.00206065496132853 | PAAD | Male-baised eQTL |
| rs4568285 | chr4:134519349:C:T | - | -0.131616161759975 | 0.00206065496132853 | PAAD | Male-baised eQTL |
| rs4543185 | chr4:134519676:A:G | - | -0.131616161759975 | 0.00206065496132853 | PAAD | Male-baised eQTL |
| rs11930014 | chr4:134520370:C:T | - | -0.131616161759975 | 0.00206065496132853 | PAAD | Male-baised eQTL |
| rs4864224 | chr4:134521302:G:T | - | -0.131616161759975 | 0.00206065496132853 | PAAD | Male-baised eQTL |
| rs13107279 | chr4:134525932:C:T | - | -0.130687354155429 | 0.00222744490766338 | PAAD | Male-baised eQTL |
| rs7665017 | chr4:134526212:T:C | - | -0.130687354155429 | 0.00222744490766338 | PAAD | Male-baised eQTL |
| rs62316118 | chr4:134521916:C:A | - | -0.130744330379997 | 0.002289910893511 | PAAD | Male-baised eQTL |
| rs4435795 | chr4:134522745:G:A | - | -0.130744330379997 | 0.002289910893511 | PAAD | Male-baised eQTL |
| rs4618369 | chr4:134523060:A:C | - | -0.130744330379997 | 0.002289910893511 | PAAD | Male-baised eQTL |
| rs10022854 | chr4:134523173:A:T | - | -0.130744330379997 | 0.002289910893511 | PAAD | Male-baised eQTL |
| rs10012548 | chr4:134523270:T:C | - | -0.130744330379997 | 0.002289910893511 | PAAD | Male-baised eQTL |
| rs6812574 | chr4:134523450:C:A | - | -0.130744330379997 | 0.002289910893511 | PAAD | Male-baised eQTL |
| rs6813365 | chr4:134523713:G:C | - | -0.130744330379997 | 0.002289910893511 | PAAD | Male-baised eQTL |
| rs6856172 | chr4:134523971:T:G | - | -0.130744330379997 | 0.002289910893511 | PAAD | Male-baised eQTL |
| rs10032077 | chr4:134524503:G:A | - | -0.130744330379997 | 0.002289910893511 | PAAD | Male-baised eQTL |
| rs4864225 | chr4:134524883:A:T | - | -0.130744330379997 | 0.002289910893511 | PAAD | Male-baised eQTL |
| rs4269231 | chr4:134525107:C:T | - | -0.130744330379997 | 0.002289910893511 | PAAD | Male-baised eQTL |
| rs4450985 | chr4:134525730:G:C | - | -0.130744330379997 | 0.002289910893511 | PAAD | Male-baised eQTL |
| rs4475198 | chr4:134528681:A:G | - | -0.130291461201861 | 0.00237683976229315 | PAAD | Male-baised eQTL |
| rs4385128 | chr4:134528940:C:A | - | -0.130291461201861 | 0.00237683976229315 | PAAD | Male-baised eQTL |
| rs4389625 | chr4:134530275:T:C | - | -0.130291461201861 | 0.00237683976229315 | PAAD | Male-baised eQTL |
| rs4557331 | chr4:134527526:A:G | - | -0.127338124162546 | 0.00332356484705061 | PAAD | Male-baised eQTL |
| rs4406069 | chr4:134520190:T:G | - | -0.132076883642112 | 0.00710672183604673 | PAAD | Male-baised eQTL |
| rs4374668 | chr4:134528697:T:G | - | -0.111056818343745 | 0.0177392023918229 | PAAD | Male-baised eQTL |
| rs12511845 | chr4:134506116:A:T | - | -0.114549490242582 | 0.0350717597599416 | PAAD | Male-baised eQTL |
| rs4438806 | chr4:134502608:C:T | - | 0.105353191445326 | 0.0412933738429835 | PAAD | Male-baised eQTL |
| rs4561947 | chr4:146378068:G:T | - | 0.0676946253924291 | 0.000905272073741285 | LUAD | Male-baised eQTL |
| rs76018317 | chr4:146392593:C:T | - | 0.0676946253924291 | 0.000905272073741285 | LUAD | Male-baised eQTL |
| rs58997046 | chr4:146400575:C:T | - | 0.0676946253924291 | 0.000905272073741285 | LUAD | Male-baised eQTL |
| rs76629701 | chr4:146382215:G:A | - | 0.0676637384572626 | 0.000921635288214571 | LUAD | Male-baised eQTL |
| rs10519805 | chr4:146401230:T:G | - | 0.0686716831124486 | 0.000932167785728429 | LUAD | Male-baised eQTL |
| rs13107210 | chr4:146655268:G:C | - | 0.0609679430510521 | 0.000961373530676914 | LUAD | Male-baised eQTL |
| rs3810843 | chr4:146640819:G:T | - | 0.0596671224896485 | 0.00119413614737855 | LUAD | Male-baised eQTL |
| rs34447546 | chr4:146656877:G:A | - | 0.0595079275184362 | 0.00129914828767168 | LUAD | Male-baised eQTL |
| rs185048985 | chr4:146656922:T:C | - | 0.0595079275184362 | 0.00129914828767168 | LUAD | Male-baised eQTL |
| rs79118085 | chr4:146376476:C:T | - | 0.065223658872512 | 0.00151443625156894 | LUAD | Male-baised eQTL |
| rs78623985 | chr4:146378951:C:T | - | 0.0651925289818539 | 0.0015389077108931 | LUAD | Male-baised eQTL |
| rs75369178 | chr4:146381385:A:G | - | 0.0651925289818539 | 0.0015389077108931 | LUAD | Male-baised eQTL |
| rs7673042 | chr4:146645392:A:G | - | 0.0581143761391823 | 0.00168088174219898 | LUAD | Male-baised eQTL |
| rs71614602 | chr4:146647024:A:T | - | 0.0580920358740585 | 0.0017098925216706 | LUAD | Male-baised eQTL |
| rs35396752 | chr4:146657691:T:A | - | 0.0574947077868799 | 0.00175227295344394 | LUAD | Male-baised eQTL |
| rs76163256 | chr4:146648442:T:C | - | 0.0550711907573143 | 0.00331108532541565 | LUAD | Male-baised eQTL |
| rs28478962 | chr4:146648701:G:T | - | 0.0550711907573143 | 0.00331108532541565 | LUAD | Male-baised eQTL |
| rs10005616 | chr4:146649485:T:A | - | 0.0550711907573143 | 0.00331108532541565 | LUAD | Male-baised eQTL |
| rs7689436 | chr4:146652536:T:C | - | 0.0550711907573143 | 0.00331108532541565 | LUAD | Male-baised eQTL |
| rs13144778 | chr4:146602999:T:A | - | 0.0531513777724142 | 0.00532453413382959 | LUAD | Male-baised eQTL |
| rs13144780 | chr4:146603000:T:A | - | 0.0531513777724142 | 0.00532453413382959 | LUAD | Male-baised eQTL |
| rs6858827 | chr4:146599228:T:C | - | 0.0524820509401378 | 0.00560574072057694 | LUAD | Male-baised eQTL |
| rs17021616 | chr4:146599827:C:T | - | 0.0524820509401378 | 0.00560574072057694 | LUAD | Male-baised eQTL |
| rs10001900 | chr4:146599926:G:T | - | 0.0524820509401378 | 0.00560574072057694 | LUAD | Male-baised eQTL |
| rs71614595 | chr4:146607513:G:T | - | 0.0524820509401378 | 0.00560574072057694 | LUAD | Male-baised eQTL |
| rs28510923 | chr4:146610396:G:A | - | 0.0524820509401378 | 0.00560574072057694 | LUAD | Male-baised eQTL |
| rs1979903 | chr4:146628151:T:G | - | 0.0518219226368268 | 0.00600370061230873 | LUAD | Male-baised eQTL |
| rs10025202 | chr4:146630177:C:T | - | 0.0518219226368268 | 0.00600370061230873 | LUAD | Male-baised eQTL |
| rs34012438 | chr4:146636134:C:T | - | 0.0517640909455322 | 0.00611808584045974 | LUAD | Male-baised eQTL |
| rs1910595 | chr4:146637085:C:A | - | 0.0517640909455322 | 0.00611808584045974 | LUAD | Male-baised eQTL |
| rs6847530 | chr4:146632233:G:A | - | 0.0517638190266908 | 0.00611867537885759 | LUAD | Male-baised eQTL |
| rs3827594 | chr4:146640502:C:G | - | 0.0486797483083275 | 0.00757306830902123 | LUAD | Male-baised eQTL |
| rs3762842 | chr4:146637412:C:G | - | 0.0445541290728241 | 0.0164304326688847 | LUAD | Male-baised eQTL |
| rs71616503 | chr4:146656756:A:T | - | 0.044544874156946 | 0.0169131477033994 | LUAD | Male-baised eQTL |
| rs13152799 | chr4:146639259:T:C | - | 0.0450615413562486 | 0.0173337788392076 | LUAD | Male-baised eQTL |
| rs6537429 | chr4:146645836:G:A | - | 0.0424585756058091 | 0.0216343983688095 | LUAD | Male-baised eQTL |
| rs10017498 | chr4:146634624:A:G | - | 0.0402745461017142 | 0.0317426450020033 | LUAD | Male-baised eQTL |
| rs10017331 | chr4:146634451:A:G | - | 0.0400469135521477 | 0.032768808704664 | LUAD | Male-baised eQTL |
| rs1979904 | chr4:146627891:C:T | - | 0.0415733004778476 | 0.0331963705761974 | LUAD | Male-baised eQTL |
| rs6856128 | chr4:146648511:T:C | - | 0.0401637919858971 | 0.0339149794082483 | LUAD | Male-baised eQTL |
| rs9996188 | chr4:146631465:C:T | - | 0.0392675887195363 | 0.0383913460738904 | LUAD | Male-baised eQTL |
| rs9996279 | chr4:146631508:C:T | - | 0.0392675887195363 | 0.0383913460738904 | LUAD | Male-baised eQTL |
| rs6825523 | chr4:146632350:A:G | - | 0.0392675887195363 | 0.0383913460738904 | LUAD | Male-baised eQTL |
| rs17021717 | chr4:146632583:T:A | - | 0.0386177707632357 | 0.0432097730675082 | LUAD | Male-baised eQTL |
| rs17021722 | chr4:146633117:C:G | - | 0.0386177707632357 | 0.0432097730675082 | LUAD | Male-baised eQTL |
| rs10024327 | chr4:146633532:G:C | - | 0.0386177707632357 | 0.0432097730675082 | LUAD | Male-baised eQTL |
| rs13134193 | chr4:146634063:G:A | - | 0.0386177707632357 | 0.0432097730675082 | LUAD | Male-baised eQTL |
| rs34375288 | chr4:146634129:A:G | - | 0.0386177707632357 | 0.0432097730675082 | LUAD | Male-baised eQTL |
| rs10011145 | chr4:146632651:A:C | - | 0.0380053520853975 | 0.0466803425230974 | LUAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of CLGN |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
