|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
|
Gene: ENSG00000110777 |
Summary for POU2AF1 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000110777 | Gene symbol | POU2AF1 |
| Gene name | POU class 2 homeobox associating factor 1 | |
| HGNC | 9211 | |
| Entrez ID | 5450 | |
| Gene type | protein_coding | |
| Synonyms | POU2AF1|OBF1|BOB1 | |
| UniProtAcc | Q16633 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for POU2AF1 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| POU2AF1 | 5.65e+02 | -2.90e+00 | 5.63e-01 | -5.15e+00 | 2.58e-07 | 2.15e-05 | BRCA |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| POU2AF1 | 2.02e+03 | 1.38e+00 | 2.66e-01 | 5.18e+00 | 2.19e-07 | 4.60e-07 | LUSC |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| POU2AF1 | 8.16e+02 | -1.46e+00 | 3.26e-01 | -4.48e+00 | 7.40e-06 | 2.13e-05 | THCA |
| POU2AF1 | 2.94e+02 | -1.84e+00 | 5.63e-01 | -3.27e+00 | 1.07e-03 | 3.70e-03 | READ |
Top |
Sex-biased somatic mutation for POU2AF1 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for POU2AF1 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUSC | cg22033281 | chr11:111455029 | CGI:chr11:111512443-111513167 | promoter,gene body | 4.50e-01 | 6.50e-01 | -4.11e+00 | 3.92e-05 | 5.33e-04 | -2.00e-01 |
| LIHC | cg22033281 | chr11:111455029 | CGI:chr11:111512443-111513167 | promoter,gene body | 5.70e-01 | 7.34e-01 | -4.78e+00 | 1.71e-06 | 5.91e-06 | -1.64e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Top |
Exon skipping events with PSI in TCGA for POU2AF1 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for POU2AF1 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for POU2AF1 |
| TFs related to POU2AF1. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| LGG | ZNF235 | POU2AF1 | 4.24e+00 | 9.86e-01 | 3.53e+00 | 2.57e-03 | Male-biased |
| LGG | ZNF287 | POU2AF1 | 4.12e+00 | 9.82e-01 | 3.46e+00 | 3.56e-03 | Male-biased |
| POU2AF1 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for POU2AF1 |
| RBPs related to ES in POU2AF1. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| POU2AF1 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000110777 | LINC00943,hsa-mir-195,POU2AF1 | Female-specific ceRNA | TCGA-THCA |
| ENSG00000110777 | FAM30A,hsa-mir-195,POU2AF1 | Female-specific ceRNA | TCGA-THCA |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs59408746 | chr11:115888678:C:T | - | 0.224878625371391 | 0.01063152322531 | HNSC | Female-baised eQTL |
| rs2186703 | chr11:115889789:T:G | - | 0.224878625371391 | 0.01063152322531 | HNSC | Female-baised eQTL |
| rs17174413 | chr11:115891114:C:A | - | 0.224878625371391 | 0.01063152322531 | HNSC | Female-baised eQTL |
| rs57142776 | chr11:115890982:G:A | - | 0.223177633397305 | 0.012772387342572 | HNSC | Female-baised eQTL |
| rs1939689 | chr11:115891459:T:A | - | 0.212015698158574 | 0.019118214341273 | HNSC | Female-baised eQTL |
| rs10502014 | chr11:103434331:C:T | - | 0.129453424944104 | 5.54029874054142e-06 | STAD | Female-baised eQTL |
| rs71464710 | chr11:103403654:A:G | - | 0.122683123498884 | 2.1005490533021e-05 | STAD | Female-baised eQTL |
| rs12798974 | chr11:103404174:A:G | - | 0.122683123498884 | 2.1005490533021e-05 | STAD | Female-baised eQTL |
| rs34114013 | chr11:103404504:T:G | - | 0.122683123498884 | 2.1005490533021e-05 | STAD | Female-baised eQTL |
| rs17093669 | chr11:103404627:T:C | - | 0.122683123498884 | 2.1005490533021e-05 | STAD | Female-baised eQTL |
| rs78163600 | chr11:103410629:A:G | - | 0.122683123498884 | 2.1005490533021e-05 | STAD | Female-baised eQTL |
| rs12791999 | chr11:103411997:C:A | - | 0.122683123498884 | 2.1005490533021e-05 | STAD | Female-baised eQTL |
| rs71480490 | chr11:103416597:T:C | - | 0.122683123498884 | 2.1005490533021e-05 | STAD | Female-baised eQTL |
| rs7928264 | chr11:103417617:G:A | - | 0.122683123498884 | 2.1005490533021e-05 | STAD | Female-baised eQTL |
| rs35366198 | chr11:103425520:T:A | - | 0.122683123498884 | 2.1005490533021e-05 | STAD | Female-baised eQTL |
| rs12796183 | chr11:103426790:G:A | - | 0.122683123498884 | 2.1005490533021e-05 | STAD | Female-baised eQTL |
| rs34084066 | chr11:103367685:G:T | - | 0.112137614920239 | 8.67609431296223e-05 | STAD | Female-baised eQTL |
| rs12796853 | chr11:103447712:A:T | - | 0.112401608402331 | 0.00046706559533631 | STAD | Female-baised eQTL |
| rs12576549 | chr11:103448100:A:G | - | 0.112401608402331 | 0.00046706559533631 | STAD | Female-baised eQTL |
| rs35782069 | chr11:103450290:G:A | - | 0.112401608402331 | 0.00046706559533631 | STAD | Female-baised eQTL |
| rs58172144 | chr11:103457536:A:C | - | 0.112347368843162 | 0.000478659975666888 | STAD | Female-baised eQTL |
| rs17100794 | chr11:103428322:G:A | - | 0.0989062055374409 | 0.000669481670442269 | STAD | Female-baised eQTL |
| rs4938131 | chr11:114780115:T:C | - | 0.120922702785268 | 0.000686907463415598 | STAD | Female-baised eQTL |
| rs80349041 | chr11:114798966:G:A | - | 0.120922702785268 | 0.000686907463415598 | STAD | Female-baised eQTL |
| rs9645679 | chr11:103407326:T:C | - | 0.0861330221136874 | 0.00304612189099494 | STAD | Female-baised eQTL |
| rs11225843 | chr11:103508724:G:A | - | 0.0957224258372368 | 0.00364355651993096 | STAD | Female-baised eQTL |
| rs11225846 | chr11:103510327:T:C | - | 0.0957224258372368 | 0.00364355651993096 | STAD | Female-baised eQTL |
| rs10502082 | chr11:107044308:G:C | - | 0.108847463306504 | 0.0039110487086599 | STAD | Female-baised eQTL |
| rs10750023 | chr11:113052882:A:G | - | -0.105970420349789 | 0.00410553645806286 | STAD | Female-baised eQTL |
| rs3910097 | chr11:103373585:A:T | - | 0.0767166049421303 | 0.00931162849931931 | STAD | Female-baised eQTL |
| rs1245089 | chr11:113066523:G:C | - | 0.0882708825852557 | 0.0267162614114895 | STAD | Female-baised eQTL |
| rs7113370 | chr11:104034057:C:T | - | 0.206418821513181 | 0.0130947348322084 | BLCA | Female-baised eQTL |
| rs1793073 | chr11:106647835:T:C | - | 0.102281793646478 | 0.023332601731354 | BLCA | Female-baised eQTL |
| rs1945848 | chr11:106648404:T:C | - | 0.0920177018995851 | 0.0443978089839626 | BLCA | Female-baised eQTL |
| rs609775 | chr11:107396489:A:C | - | 0.121198262356545 | 0.000775107075731199 | COAD | Female-baised eQTL |
| rs7121399 | chr11:107385099:T:C | - | 0.128322682003787 | 0.00135233585127311 | COAD | Female-baised eQTL |
| rs73547700 | chr11:107389131:A:C | - | 0.128322682003787 | 0.00135233585127311 | COAD | Female-baised eQTL |
| rs58122182 | chr11:107395345:C:T | - | 0.128161767925025 | 0.00138254812779086 | COAD | Female-baised eQTL |
| rs1317912 | chr11:120632928:G:A | - | 0.0823402157206397 | 0.00307192066145289 | COAD | Female-baised eQTL |
| rs5744281 | chr11:112145470:T:C | - | 0.0852273927745323 | 0.0050904093864836 | COAD | Female-baised eQTL |
| rs17103984 | chr11:105215007:G:A | - | 0.101325377666259 | 0.00593421164885089 | COAD | Female-baised eQTL |
| rs13377527 | chr11:105216206:C:T | - | 0.101325377666259 | 0.00593421164885089 | COAD | Female-baised eQTL |
| rs61536732 | chr11:105217446:T:C | - | 0.101325377666259 | 0.00593421164885089 | COAD | Female-baised eQTL |
| rs56729117 | chr11:105219111:C:T | - | 0.101325377666259 | 0.00593421164885089 | COAD | Female-baised eQTL |
| rs7940032 | chr11:105219984:G:C | - | 0.101325377666259 | 0.00593421164885089 | COAD | Female-baised eQTL |
| rs9888195 | chr11:105220606:A:C | - | 0.101325377666259 | 0.00593421164885089 | COAD | Female-baised eQTL |
| rs9888157 | chr11:105220811:C:T | - | 0.101325377666259 | 0.00593421164885089 | COAD | Female-baised eQTL |
| rs7101358 | chr11:105222749:C:A | - | 0.101325377666259 | 0.00593421164885089 | COAD | Female-baised eQTL |
| rs11828526 | chr11:110688090:C:G | - | 0.0894755146076829 | 0.0113213800998752 | COAD | Female-baised eQTL |
| rs11213546 | chr11:110702718:C:A | - | 0.0894755146076829 | 0.0113213800998752 | COAD | Female-baised eQTL |
| rs2048041 | chr11:110709874:A:T | - | 0.0894732242764037 | 0.0113255576801295 | COAD | Female-baised eQTL |
| rs7929561 | chr11:110685759:G:A | - | 0.0832510795561266 | 0.0116631565873627 | COAD | Female-baised eQTL |
| rs2726873 | chr11:108810339:G:A | - | 0.068119812669803 | 0.0125356814831535 | COAD | Female-baised eQTL |
| rs7938499 | chr11:110678062:A:G | - | 0.0797302595201123 | 0.0137890525753714 | COAD | Female-baised eQTL |
| rs73563832 | chr11:110695529:T:C | - | 0.0797302595201123 | 0.0137890525753714 | COAD | Female-baised eQTL |
| rs12280447 | chr11:110696264:T:C | - | 0.0797302595201123 | 0.0137890525753714 | COAD | Female-baised eQTL |
| rs7117008 | chr11:110696762:T:C | - | 0.0797302595201123 | 0.0137890525753714 | COAD | Female-baised eQTL |
| rs10891166 | chr11:110698163:A:G | - | 0.0797302595201123 | 0.0137890525753714 | COAD | Female-baised eQTL |
| rs7947149 | chr11:110698908:T:C | - | 0.0797302595201123 | 0.0137890525753714 | COAD | Female-baised eQTL |
| rs11213553 | chr11:110704556:T:C | - | 0.0797302595201123 | 0.0137890525753714 | COAD | Female-baised eQTL |
| rs11212704 | chr11:108555063:T:C | - | 0.0649752015979712 | 0.0147897125240402 | COAD | Female-baised eQTL |
| rs6589804 | chr11:120290932:G:A | - | 0.0848888770810975 | 0.0160083095801747 | COAD | Female-baised eQTL |
| rs7129597 | chr11:117685218:C:T | - | 0.0787183609265971 | 0.0164430754765923 | COAD | Female-baised eQTL |
| rs59071712 | chr11:117686509:T:A | - | 0.0783124536050978 | 0.0178613955445149 | COAD | Female-baised eQTL |
| rs583905 | chr11:118825199:G:A | - | -0.0661897269218939 | 0.0182318125821908 | COAD | Female-baised eQTL |
| rs577121 | chr11:118819841:C:T | - | -0.0654132536717152 | 0.0209811823819979 | COAD | Female-baised eQTL |
| rs11226667 | chr11:105226249:G:T | - | 0.0885846575870557 | 0.0213477454637131 | COAD | Female-baised eQTL |
| rs10891180 | chr11:110842124:C:G | - | 0.0755605441038306 | 0.0257894865438017 | COAD | Female-baised eQTL |
| rs721486 | chr11:117686825:A:G | - | 0.0747700294453343 | 0.0270295334582984 | COAD | Female-baised eQTL |
| rs1115447 | chr11:110600514:C:A | - | 0.0716570989385146 | 0.0295694344342448 | COAD | Female-baised eQTL |
| rs11213499 | chr11:110604766:T:C | - | 0.0716570989385146 | 0.0295694344342448 | COAD | Female-baised eQTL |
| rs2615757 | chr11:108815369:G:A | - | 0.063570723419815 | 0.0295951218868342 | COAD | Female-baised eQTL |
| rs79663212 | chr11:116426200:G:T | - | 0.114834198225549 | 0.0301083904312327 | COAD | Female-baised eQTL |
| rs7114768 | chr11:105021000:T:C | - | 0.0622081746442556 | 0.0312511106162113 | COAD | Female-baised eQTL |
| rs7102109 | chr11:110691855:A:G | - | 0.0727117655933534 | 0.0332976985461576 | COAD | Female-baised eQTL |
| rs7117632 | chr11:105283387:A:G | - | 0.0798387935174416 | 0.0338519769733714 | COAD | Female-baised eQTL |
| rs7939663 | chr11:105262319:C:A | - | 0.0796922160081996 | 0.0347018840219314 | COAD | Female-baised eQTL |
| rs149473281 | chr11:105265250:G:A | - | 0.0796922160081996 | 0.0347018840219314 | COAD | Female-baised eQTL |
| rs75881428 | chr11:105267894:C:T | - | 0.0796922160081996 | 0.0347018840219314 | COAD | Female-baised eQTL |
| rs12574455 | chr11:105268674:G:A | - | 0.0796922160081996 | 0.0347018840219314 | COAD | Female-baised eQTL |
| rs74709921 | chr11:105269400:C:A | - | 0.0796922160081996 | 0.0347018840219314 | COAD | Female-baised eQTL |
| rs77493124 | chr11:105272942:C:T | - | 0.0796922160081996 | 0.0347018840219314 | COAD | Female-baised eQTL |
| rs80157688 | chr11:105277195:A:T | - | 0.0796922160081996 | 0.0347018840219314 | COAD | Female-baised eQTL |
| rs7109143 | chr11:105277781:G:C | - | 0.0796922160081996 | 0.0347018840219314 | COAD | Female-baised eQTL |
| rs76857944 | chr11:105279472:C:A | - | 0.0796922160081996 | 0.0347018840219314 | COAD | Female-baised eQTL |
| rs10890859 | chr11:108552145:A:G | - | 0.0605594573170919 | 0.0347557948265645 | COAD | Female-baised eQTL |
| rs12289021 | chr11:103661920:T:C | - | 0.0808908616793084 | 0.0348700482476751 | COAD | Female-baised eQTL |
| rs12272930 | chr11:103665095:G:T | - | 0.0808908616793084 | 0.0348700482476751 | COAD | Female-baised eQTL |
| rs11607289 | chr11:120292865:A:G | - | 0.0731797139034869 | 0.0362650313782235 | COAD | Female-baised eQTL |
| rs11603274 | chr11:120293221:G:A | - | 0.0731797139034869 | 0.0362650313782235 | COAD | Female-baised eQTL |
| rs11603307 | chr11:120293432:G:A | - | 0.0731797139034869 | 0.0362650313782235 | COAD | Female-baised eQTL |
| rs11603757 | chr11:120293949:G:T | - | 0.0731797139034869 | 0.0362650313782235 | COAD | Female-baised eQTL |
| rs1354975 | chr11:116481622:C:T | - | 0.0570189847077711 | 0.0364969634890357 | COAD | Female-baised eQTL |
| rs7944427 | chr11:117434745:C:T | - | 0.0605917840266849 | 0.0379056571788038 | COAD | Female-baised eQTL |
| rs2615733 | chr11:108832242:C:T | - | 0.0630048445989848 | 0.0388093030033513 | COAD | Female-baised eQTL |
| rs7121960 | chr11:105202942:C:G | - | 0.0780390962935062 | 0.0435693720530061 | COAD | Female-baised eQTL |
| rs61906114 | chr11:116686328:G:C | - | 0.0765371154317932 | 0.0493142755899305 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs7117466 | chr11:107481326:A:G | - | 0.0456366335999607 | 0.00524126101345459 | HNSC | Male-baised eQTL |
| rs2435922 | chr11:103131752:T:C | - | -0.0370918548918733 | 0.0348297718844528 | HNSC | Male-baised eQTL |
| rs471079 | chr11:109353656:T:A | - | 0.055976247253688 | 0.0301252743001125 | BLCA | Male-baised eQTL |
| rs11213050 | chr11:109357590:A:G | - | 0.0559537727294352 | 0.0302611095336999 | BLCA | Male-baised eQTL |
| rs12289219 | chr11:109372036:A:G | - | 0.0559396531355316 | 0.0304069199207208 | BLCA | Male-baised eQTL |
| rs12272157 | chr11:109369519:G:A | - | 0.0540716604099917 | 0.038979327727737 | BLCA | Male-baised eQTL |
| rs11213057 | chr11:109383853:T:A | - | 0.0516348344140249 | 0.039278548203886 | BLCA | Male-baised eQTL |
| rs514984 | chr11:109348330:C:T | - | 0.0537622136304105 | 0.0410484735940183 | BLCA | Male-baised eQTL |
| rs659092 | chr11:118047247:T:C | - | 0.0674526969433782 | 0.034691411226374 | COAD | Male-baised eQTL |
| rs59238367 | chr11:118049385:G:A | - | 0.0674526969433782 | 0.034691411226374 | COAD | Male-baised eQTL |
| rs2845695 | chr11:118044810:A:C | - | 0.0659660499077083 | 0.0396550211694645 | COAD | Male-baised eQTL |
| rs73000004 | chr11:115548930:G:A | - | 0.0616730702229572 | 0.0447734877695338 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000110777 |
| CpG Site: cg24049888 | |
| Position to Gene: gene,exon,UTR | |
| Male Effect: - | |
| Female Effect: -0.488698857498521 | |
 | Gene ID: ENSG00000110777 |
| CpG Site: cg18316498 | |
| Position to Gene: gene,exon,UTR | |
| Male Effect: - | |
| Female Effect: -0.488698857498521 | |
 | Gene ID: ENSG00000110777 |
| CpG Site: cg11362935 | |
| Position to Gene: gene,exon,UTR | |
| Male Effect: - | |
| Female Effect: -0.488698857498521 | |
 | Gene ID: ENSG00000110777 |
| CpG Site: cg20140034 | |
| Position to Gene: gene,exon,UTR | |
| Male Effect: - | |
| Female Effect: -0.488698857498521 | |
 | Gene ID: ENSG00000110777 |
| CpG Site: cg10694914 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.488698857498521 | |
 | Gene ID: ENSG00000110777 |
| CpG Site: cg14592365 | |
| Position to Gene: gene | |
| Male Effect: -0.462234414457061 | |
| Female Effect: - | |
 | Gene ID: ENSG00000110777 |
| CpG Site: cg01212326 | |
| Position to Gene: gene,exon,UTR | |
| Male Effect: -0.0592576483808397 | |
| Female Effect: - | |
 | Gene ID: ENSG00000110777 |
| CpG Site: cg14592365 | |
| Position to Gene: gene | |
| Male Effect: -0.248104707559426 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg14592365 | chr11:111417375 | gene | -0.462234414457061 | 2.77749958706994e-19 | -0.5488377513685572 | 4.111935405744306e-23 | LUSC |
| cg01212326 | chr11:111379561 | gene,exon,UTR | -0.0592576483808397 | 1.75445002472968e-08 | -0.3880092620950396 | 2.383180971664224e-11 | LUSC |
| cg14592365 | chr11:111417375 | gene | -0.248104707559426 | 1.36837830543013e-09 | -0.39740689665407847 | 1.7332155288378614e-12 | SKCM |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg24049888 | chr11:111379404 | gene,exon,UTR | -0.488698857498521 | 6.7281079220559e-53 | -0.9431688571593443 | 2.4737278525603722e-57 | STAD |
| cg18316498 | chr11:111379471 | gene,exon,UTR | -0.488698857498521 | 6.7281079220559e-53 | -0.9431688571593443 | 2.4737278525603722e-57 | STAD |
| cg11362935 | chr11:111379476 | gene,exon,UTR | -0.488698857498521 | 6.7281079220559e-53 | -0.9431688571593443 | 2.4737278525603722e-57 | STAD |
| cg20140034 | chr11:111379630 | gene,exon,UTR | -0.488698857498521 | 6.7281079220559e-53 | -0.9431688571593443 | 2.4737278525603722e-57 | STAD |
| cg10694914 | chr11:111379706 | gene | -0.488698857498521 | 6.7281079220559e-53 | -0.9431688571593443 | 2.4737278525603722e-57 | STAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of POU2AF1 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
