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Gene: ENSG00000092841 |
Summary for MYL6 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000092841 | Gene symbol | MYL6 |
| Gene name | myosin light chain 6 | |
| HGNC | 7587 | |
| Entrez ID | 4637 | |
| Gene type | protein_coding | |
| Synonyms | MYL6|ESMLC|MLC3NM|MLC1SM | |
| UniProtAcc | P60660 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for MYL6 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| MYL6 | 4.65e+04 | -1.11e+00 | 2.27e-01 | -4.89e+00 | 1.02e-06 | 7.89e-06 | BLCA |
| MYL6 | 2.87e+04 | -1.02e+00 | 1.54e-01 | -6.66e+00 | 2.81e-11 | 2.03e-10 | COAD |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| MYL6 | 3.22e+04 | -1.48e+00 | 2.43e-01 | -6.09e+00 | 1.14e-09 | 2.33e-08 | READ |
Top |
Sex-biased somatic mutation for MYL6 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for MYL6 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Top |
Exon skipping events with PSI in TCGA for MYL6 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| BLCA | exon_skip_84124 | 6.28e-01 | 4.88e-01 | 2.34e+00 | 1.91e-02 | 3.02e-02 | 1.40e-01 |
| KIRP | exon_skip_84121 | 7.02e-01 | 5.94e-01 | 3.86e+00 | 1.15e-04 | 7.64e-04 | 1.08e-01 |
| KIRP | exon_skip_84124 | 3.12e-01 | 4.22e-01 | -4.81e+00 | 1.48e-06 | 2.79e-05 | -1.10e-01 |
| ESCA | exon_skip_84118 | 1.26e-01 | 2.29e-01 | -2.83e+00 | 4.59e-03 | 1.76e-02 | -1.03e-01 |
| ESCA | exon_skip_84119 | 5.65e-01 | 7.76e-01 | -3.44e+00 | 5.72e-04 | 8.46e-03 | -2.11e-01 |
| ESCA | exon_skip_84124 | 4.23e-01 | 2.53e-01 | 2.50e+00 | 1.25e-02 | 2.67e-02 | 1.70e-01 |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| BRCA | exon_skip_84124 | 4.98e-01 | 6.85e-01 | -1.22e+01 | 5.51e-34 | 4.55e-32 | -1.87e-01 |
| STAD | exon_skip_84118 | 1.26e-01 | 2.38e-01 | -2.92e+00 | 3.49e-03 | 1.44e-02 | -1.13e-01 |
| READ | exon_skip_84119 | 4.23e-01 | 5.93e-01 | -3.59e+00 | 3.36e-04 | 4.80e-03 | -1.71e-01 |
| READ | exon_skip_84121 | 6.57e-01 | 7.79e-01 | -3.56e+00 | 3.77e-04 | 4.80e-03 | -1.22e-01 |
| READ | exon_skip_84124 | 3.56e-01 | 2.04e-01 | 2.84e+00 | 4.53e-03 | 1.45e-02 | 1.52e-01 |
Top |
RNA A-to-I editing events in TCGA for MYL6 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for MYL6 |
| TFs related to MYL6. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| READ | GLIS1 | MYL6 | 4.20e+00 | 9.85e-01 | 2.91e+00 | 1.57e-03 | Male-biased |
| READ | NFKB2 | MYL6 | 4.13e+00 | 9.84e-01 | 2.58e+00 | 5.97e-04 | Male-biased |
| MYL6 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for MYL6 |
| RBPs related to ES in MYL6. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| LUSC | ESRP2 | exon_skip_84120 | 7.46e+00 | 9.83e-01 | 7.03e+00 | 6.21e-03 | Male-biased |
| BRCA | BRUNOL6 | exon_skip_84120 | 6.88e+00 | 8.60e-04 | 8.36e+00 | 9.92e-01 | Female-biased |
| BRCA | BRUNOL6 | exon_skip_84121 | 6.95e+00 | 1.41e-03 | 8.23e+00 | 9.91e-01 | Female-biased |
| BRCA | ESRP2 | exon_skip_84120 | 6.73e+00 | 3.43e-03 | 7.68e+00 | 9.87e-01 | Female-biased |
| BRCA | ESRP2 | exon_skip_84121 | 6.60e+00 | 3.36e-03 | 7.55e+00 | 9.86e-01 | Female-biased |
| ESCA | BRUNOL6 | exon_skip_84120 | 7.60e+00 | 9.86e-01 | 7.04e+00 | 4.48e-03 | Male-biased |
| ESCA | BRUNOL6 | exon_skip_84121 | 7.47e+00 | 9.80e-01 | 7.02e+00 | 9.67e-03 | Male-biased |
| ESCA | ESRP2 | exon_skip_84120 | 7.24e+00 | 9.82e-01 | 6.74e+00 | 6.37e-03 | Male-biased |
| PAAD | BRUNOL6 | exon_skip_84121 | 6.68e+00 | 1.35e-03 | 7.15e+00 | 9.86e-01 | Female-biased |
| KIRC | BRUNOL6 | exon_skip_84120 | 6.97e+00 | 5.58e-04 | 7.58e+00 | 9.90e-01 | Female-biased |
| KIRC | ESRP2 | exon_skip_84120 | 6.76e+00 | 4.70e-04 | 7.39e+00 | 9.89e-01 | Female-biased |
| HNSC | BRUNOL6 | exon_skip_84120 | 7.71e+00 | 9.86e-01 | 7.27e+00 | 4.25e-03 | Male-biased |
| MYL6 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs10747590 | chr12:50766554:T:G | - | -0.186345501952922 | 0.0284875611004281 | KIRP | Female-baised eQTL |
| rs4768920 | chr12:50772812:G:A | - | -0.186345501952922 | 0.0284875611004281 | KIRP | Female-baised eQTL |
| rs6580766 | chr12:50775964:A:G | - | -0.186345501952922 | 0.0284875611004281 | KIRP | Female-baised eQTL |
| rs12578427 | chr12:53109065:C:T | - | 0.0564596672499332 | 0.0021964680850516 | LGG | Female-baised eQTL |
| rs12230946 | chr12:53104941:G:A | - | 0.0547288167989094 | 0.00324474758558048 | LGG | Female-baised eQTL |
| rs11170421 | chr12:53112581:A:G | - | 0.0544773622126672 | 0.00552028290426047 | LGG | Female-baised eQTL |
| rs61922663 | chr12:63033886:C:T | - | 0.050471434894882 | 0.0117410659172011 | LGG | Female-baised eQTL |
| rs66671152 | chr12:52713823:C:T | - | 0.055167222482224 | 0.0138154186502975 | LGG | Female-baised eQTL |
| rs34864714 | chr12:52717380:G:A | - | 0.055167222482224 | 0.0138154186502975 | LGG | Female-baised eQTL |
| rs11611567 | chr12:52717945:C:G | - | 0.055167222482224 | 0.0138154186502975 | LGG | Female-baised eQTL |
| rs12821123 | chr12:52721064:A:T | - | 0.055167222482224 | 0.0138154186502975 | LGG | Female-baised eQTL |
| rs12369352 | chr12:52724403:C:A | - | 0.0523965103333402 | 0.0170618033205886 | LGG | Female-baised eQTL |
| rs11170244 | chr12:52726281:T:C | - | 0.0523965103333402 | 0.0170618033205886 | LGG | Female-baised eQTL |
| rs7301507 | chr12:52727916:A:C | - | 0.0523965103333402 | 0.0170618033205886 | LGG | Female-baised eQTL |
| rs112743107 | chr12:57667733:C:T | - | 0.0570411067355686 | 0.0210116900966395 | LGG | Female-baised eQTL |
| rs12371688 | chr12:52729130:G:A | - | 0.0507083187867069 | 0.0279681874019448 | LGG | Female-baised eQTL |
| rs3782399 | chr12:54496155:A:G | - | 0.0505194144424649 | 0.0302676918204925 | LGG | Female-baised eQTL |
| rs61920303 | chr12:62942213:G:T | - | 0.0476946988978784 | 0.0327981927424911 | LGG | Female-baised eQTL |
| rs12297847 | chr12:54489740:C:T | - | 0.0495084240055416 | 0.034606791935827 | LGG | Female-baised eQTL |
| rs11170922 | chr12:54480060:G:A | - | 0.0492946545738701 | 0.0364129661018811 | LGG | Female-baised eQTL |
| rs61920305 | chr12:62944845:G:A | - | 0.0468510517399144 | 0.0372517806040951 | LGG | Female-baised eQTL |
| rs12230183 | chr12:62945335:G:T | - | 0.0468510517399144 | 0.0372517806040951 | LGG | Female-baised eQTL |
| rs11174725 | chr12:62946547:G:A | - | 0.0468510517399144 | 0.0372517806040951 | LGG | Female-baised eQTL |
| rs11170245 | chr12:52729496:G:A | - | 0.0469633144743432 | 0.0470321116953975 | LGG | Female-baised eQTL |
| rs143968460 | chr12:54488939:C:G | - | 0.047778604355253 | 0.0474252039636425 | LGG | Female-baised eQTL |
| rs7959882 | chr12:54490231:A:G | - | 0.047778604355253 | 0.0474252039636425 | LGG | Female-baised eQTL |
| rs11170920 | chr12:54477873:G:T | - | 0.0475634891751504 | 0.0498408974371123 | LGG | Female-baised eQTL |
| rs7299852 | chr12:54479154:C:A | - | 0.0475634891751504 | 0.0498408974371123 | LGG | Female-baised eQTL |
| rs7300026 | chr12:54479335:A:G | - | 0.0475634891751504 | 0.0498408974371123 | LGG | Female-baised eQTL |
| rs7313377 | chr12:54482644:A:T | - | 0.0475634891751504 | 0.0498408974371123 | LGG | Female-baised eQTL |
| rs7294423 | chr12:54483075:G:A | - | 0.0475634891751504 | 0.0498408974371123 | LGG | Female-baised eQTL |
| rs1859443 | chr12:48005829:G:A | - | 0.0624363183640262 | 0.028644219610339 | LUAD | Female-baised eQTL |
| rs11168350 | chr12:48008845:G:C | - | 0.0619352931276628 | 0.0309058998044836 | LUAD | Female-baised eQTL |
| rs9804751 | chr12:48010134:T:C | - | 0.0591875498863139 | 0.0424417739718196 | LUAD | Female-baised eQTL |
| rs9669263 | chr12:48002427:C:T | - | 0.0598274528670541 | 0.0485813364012891 | LUAD | Female-baised eQTL |
| rs56254002 | chr12:55588627:G:A | - | 0.118227926080604 | 0.0237293126908965 | COAD | Female-baised eQTL |
| rs191152992 | chr12:55591171:G:A | - | 0.118227926080604 | 0.0237293126908965 | COAD | Female-baised eQTL |
| rs149526946 | chr12:55592639:C:T | - | 0.118227926080604 | 0.0237293126908965 | COAD | Female-baised eQTL |
| rs139781066 | chr12:55593925:A:G | - | 0.118227926080604 | 0.0237293126908965 | COAD | Female-baised eQTL |
| rs1048371 | chr12:54854573:G:T | - | 0.0514758413575184 | 0.0334332285625798 | COAD | Female-baised eQTL |
| rs76089352 | chr12:61417954:T:G | - | 0.0600894447684541 | 0.0405494202058216 | COAD | Female-baised eQTL |
| rs7972087 | chr12:61437787:A:G | - | 0.0594899744753544 | 0.0421015744057068 | COAD | Female-baised eQTL |
| rs60877833 | chr12:61408749:G:A | - | 0.0594980828856388 | 0.042939315988321 | COAD | Female-baised eQTL |
| rs73114982 | chr12:55630340:G:A | - | 0.105954790434503 | 0.0459068536231326 | COAD | Female-baised eQTL |
| rs11173963 | chr12:61400595:G:A | - | 0.058962982579209 | 0.047497316199673 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs4760262 | chr12:59119560:G:A | - | 0.0890831181697359 | 0.049464793929858 | LIHC | Male-baised eQTL |
| rs4760263 | chr12:59119655:A:T | - | 0.0890831181697359 | 0.049464793929858 | LIHC | Male-baised eQTL |
| rs74666862 | chr12:59122353:A:T | - | 0.0890831181697359 | 0.049464793929858 | LIHC | Male-baised eQTL |
| rs79833984 | chr12:53940212:A:C | - | 0.0592191611934522 | 0.0278629478208068 | BLCA | Male-baised eQTL |
| rs10467077 | chr12:65538847:A:G | - | 0.163935402967585 | 0.00956940019632326 | LUAD | Male-baised eQTL |
| rs17122378 | chr12:53039194:T:C | - | 0.136698977315655 | 0.0106490719394863 | LUAD | Male-baised eQTL |
| rs1532326 | chr12:65523408:A:G | - | 0.0811996493175744 | 0.0244735242690814 | LUAD | Male-baised eQTL |
| rs7980047 | chr12:61768770:G:A | - | 0.0533979453603169 | 0.0101288489366872 | COAD | Male-baised eQTL |
| rs10877732 | chr12:61746253:C:T | - | 0.0535803018486841 | 0.0123509359145405 | COAD | Male-baised eQTL |
| rs10784260 | chr12:61747812:A:G | - | 0.0535803018486841 | 0.0123509359145405 | COAD | Male-baised eQTL |
| rs7961921 | chr12:61748820:A:T | - | 0.0535803018486841 | 0.0123509359145405 | COAD | Male-baised eQTL |
| rs7956809 | chr12:52808399:C:G | - | 0.0896113624048939 | 0.0126888365133323 | COAD | Male-baised eQTL |
| rs80269830 | chr12:55323246:A:T | - | 0.0683123684519089 | 0.0156075560550688 | COAD | Male-baised eQTL |
| rs3816880 | chr12:52807896:C:T | - | 0.0859233783060779 | 0.0165686190010254 | COAD | Male-baised eQTL |
| rs11171413 | chr12:55331406:T:G | - | 0.0673263467025257 | 0.0178733824827236 | COAD | Male-baised eQTL |
| rs10877102 | chr12:58339974:G:A | - | 0.0620640154707802 | 0.0189632848114479 | COAD | Male-baised eQTL |
| rs10784265 | chr12:61815712:T:C | - | -0.0478720032323857 | 0.0201737637187538 | COAD | Male-baised eQTL |
| rs11174910 | chr12:63264992:A:G | - | -0.055087928139497 | 0.0215961755253407 | COAD | Male-baised eQTL |
| rs10784350 | chr12:63265639:A:C | - | -0.055087928139497 | 0.0215961755253407 | COAD | Male-baised eQTL |
| rs17121185 | chr12:58609700:A:T | - | -0.0606949740741422 | 0.0245163896738916 | COAD | Male-baised eQTL |
| rs7966375 | chr12:61802067:A:G | - | -0.0471259655104088 | 0.024869821414817 | COAD | Male-baised eQTL |
| rs7957748 | chr12:61805330:C:T | - | -0.0471259655104088 | 0.024869821414817 | COAD | Male-baised eQTL |
| rs10877747 | chr12:61809531:T:C | - | -0.0471032002883856 | 0.0249914033135397 | COAD | Male-baised eQTL |
| rs10877741 | chr12:61776167:T:C | - | 0.0485463167724687 | 0.0296282508222136 | COAD | Male-baised eQTL |
| rs11174190 | chr12:61832138:A:G | - | 0.0501907591629863 | 0.03061518999206 | COAD | Male-baised eQTL |
| rs7303726 | chr12:52804173:A:G | - | 0.0863090879054576 | 0.0308865930834084 | COAD | Male-baised eQTL |
| rs7307646 | chr12:61747325:T:G | - | 0.0476859964607907 | 0.0313224404815481 | COAD | Male-baised eQTL |
| rs12368938 | chr12:61792119:A:T | - | 0.047337517114917 | 0.0333297078157299 | COAD | Male-baised eQTL |
| rs7979443 | chr12:61828641:C:G | - | 0.0487745679380585 | 0.0349655912345428 | COAD | Male-baised eQTL |
| rs10877750 | chr12:61828226:A:C | - | 0.0484636946631721 | 0.0360990884344057 | COAD | Male-baised eQTL |
| rs10877103 | chr12:58340144:C:G | - | 0.0591643879843088 | 0.0364257831158135 | COAD | Male-baised eQTL |
| rs10877096 | chr12:58311450:A:T | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs11172533 | chr12:58311779:C:G | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs10877097 | chr12:58312195:C:T | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs10877099 | chr12:58314370:G:A | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs10128909 | chr12:58318905:G:A | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs10128994 | chr12:58318947:T:C | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs1852793 | chr12:58319796:C:T | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs10128826 | chr12:58321100:A:G | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs12297015 | chr12:58322255:T:A | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs11172540 | chr12:58323382:A:G | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs12317979 | chr12:58324847:T:A | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs3847701 | chr12:58325969:G:A | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs11172544 | chr12:58326946:G:A | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs35906588 | chr12:58327716:T:C | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs11832860 | chr12:58338087:T:G | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs57782897 | chr12:58338319:C:T | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs11172546 | chr12:58338841:G:A | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs61922271 | chr12:58339148:C:T | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs61922272 | chr12:58339271:G:C | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs17504503 | chr12:58339391:C:T | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs11172547 | chr12:58339730:C:G | - | 0.0587171400450615 | 0.0380660822920832 | COAD | Male-baised eQTL |
| rs11174177 | chr12:61796027:T:A | - | 0.0480343300287342 | 0.0402891196578709 | COAD | Male-baised eQTL |
| rs199966335 | chr12:58328525:C:T | - | 0.0582697144402189 | 0.0410303525815419 | COAD | Male-baised eQTL |
| rs10783886 | chr12:58323346:C:T | - | 0.0572664833123877 | 0.0417563442830737 | COAD | Male-baised eQTL |
| rs10747799 | chr12:58323759:A:G | - | 0.0572664833123877 | 0.0417563442830737 | COAD | Male-baised eQTL |
| rs10783887 | chr12:58323786:G:T | - | 0.0572664833123877 | 0.0417563442830737 | COAD | Male-baised eQTL |
| rs11172542 | chr12:58324488:A:G | - | 0.0572664833123877 | 0.0417563442830737 | COAD | Male-baised eQTL |
| rs61921204 | chr12:58327511:C:T | - | 0.0572664833123877 | 0.0417563442830737 | COAD | Male-baised eQTL |
| rs11168308 | chr12:47926137:G:T | - | -0.0500568453745869 | 0.0433392297976788 | COAD | Male-baised eQTL |
| rs718702 | chr12:58341496:G:C | - | 0.0568319389402386 | 0.0445588894221441 | COAD | Male-baised eQTL |
| rs10877095 | chr12:58306785:G:A | - | 0.0577040986127082 | 0.0456104294634401 | COAD | Male-baised eQTL |
| rs10877746 | chr12:61796889:T:A | - | 0.0465608462532391 | 0.045808907790626 | COAD | Male-baised eQTL |
| rs7967972 | chr12:63251148:T:C | - | -0.0476961180339673 | 0.0466337248321003 | COAD | Male-baised eQTL |
| rs4763166 | chr12:61850139:A:G | - | -0.0435364381688853 | 0.0484711839718518 | COAD | Male-baised eQTL |
| rs1846397 | chr12:63253076:A:T | - | -0.0473135667184201 | 0.0493521808228236 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_84124 | chr12:56160625:56160670 | 3UTR-3CDS | rs12228282 | chr12:55689862:C:G | Distant upstream | 0.0399168625595967 | 0.0325117751276822 | KIRC | Male-baised sQTL |
| exon_skip_84124 | chr12:56160625:56160670 | 3UTR-3CDS | rs2293410 | chr12:55694989:C:T | Distant upstream | 0.0393864110525941 | 0.0326666138545988 | KIRC | Male-baised sQTL |
| exon_skip_84124 | chr12:56160625:56160670 | 3UTR-3CDS | rs7953669 | chr12:55694422:T:C | Distant upstream | 0.0389603430247199 | 0.0346651130825599 | KIRC | Male-baised sQTL |
| exon_skip_84124 | chr12:56160625:56160670 | 3UTR-3CDS | rs7974721 | chr12:55696254:C:T | Distant upstream | 0.038575857636109 | 0.0446085231861999 | KIRC | Male-baised sQTL |
| exon_skip_84124 | chr12:56160625:56160670 | 3UTR-3CDS | rs3817532 | chr12:55695425:C:T | Distant upstream | 0.0385739445314356 | 0.0446309129624473 | KIRC | Male-baised sQTL |
| exon_skip_84124 | chr12:56160625:56160670 | 3UTR-3CDS | rs4143553 | chr12:55695128:C:T | Distant upstream | 0.0380515164898 | 0.0451413389083199 | KIRC | Male-baised sQTL |
| exon_skip_84124 | chr12:56160625:56160670 | 3UTR-3CDS | rs12304445 | chr12:55695185:C:G | Distant upstream | 0.0380515164898 | 0.0451413389083199 | KIRC | Male-baised sQTL |
| exon_skip_84124 | chr12:56160625:56160670 | 3UTR-3CDS | rs10783769 | chr12:55702227:T:C | Distant upstream | 0.0383910240942666 | 0.0497864606942156 | KIRC | Male-baised sQTL |
| exon_skip_84124 | chr12:56160625:56160670 | 3UTR-3CDS | rs2293414 | chr12:55703241:A:C | Distant upstream | 0.0383910240942666 | 0.0497864606942156 | KIRC | Male-baised sQTL |
| exon_skip_84124 | chr12:56160625:56160670 | 3UTR-3CDS | rs10783770 | chr12:55702274:G:A | Distant upstream | 0.0383846226183306 | 0.0498750579733944 | KIRC | Male-baised sQTL |
| exon_skip_84124 | chr12:56160625:56160670 | 3UTR-3CDS | rs7970844 | chr12:55702690:A:G | Distant upstream | 0.0383846226183306 | 0.0498750579733944 | KIRC | Male-baised sQTL |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of MYL6 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
