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Gene: ENSG00000009335 |
Summary for UBE3C |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000009335 | Gene symbol | UBE3C |
| Gene name | ubiquitin protein ligase E3C | |
| HGNC | 16803 | |
| Entrez ID | 9690 | |
| Gene type | protein_coding | |
| Synonyms | UBE3C|KIAA0010|KIAA10 | |
| UniProtAcc | Q15386 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for UBE3C |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| UBE3C | 8.27e+03 | 1.13e+00 | 1.22e-01 | 9.26e+00 | 2.13e-20 | 4.93e-19 | KICH |
Top |
Sex-biased somatic mutation for UBE3C |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for UBE3C |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg05182265 | chr7:157140512 | CGI:chr7:157138475-157139666 | promoter,gene body | 6.16e-01 | 7.65e-01 | -2.16e+00 | 3.10e-02 | 4.15e-02 | -1.49e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUSC | cg05182265 | chr7:157140512 | CGI:chr7:157138475-157139666 | promoter,gene body | 5.11e-01 | 6.49e-01 | -2.30e+00 | 2.13e-02 | 2.51e-02 | -1.38e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| COAD | cg05182265 | chr7:157140512 | CGI:chr7:157138475-157139666 | promoter,gene body | 4.39e-01 | 5.83e-01 | -2.31e+00 | 2.07e-02 | 2.67e-02 | -1.44e-01 |
Top |
Exon skipping events with PSI in TCGA for UBE3C |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for UBE3C |
| ∗Please access CAeditome for RNA editing annotation. |
| Landscape of RNA editing events across multiple cancer types. |
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| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| LUAD | UBE3C-008 | chr7_157232530_+ | 2.39e-01 | 3.04e-01 | -2.64e+00 | 8.40e-03 | 2.71e-02 | -6.50e-02 |
| LUSC | UBE3C-008 | chr7_157232459_+ | 2.07e-01 | 1.33e-01 | 2.37e+00 | 1.77e-02 | 4.91e-02 | 7.35e-02 |
| SKCM | UBE3C-008 | chr7_157232530_+ | 2.98e-01 | 2.21e-01 | 1.99e+00 | 4.63e-02 | 4.90e-02 | 7.76e-02 |
| COAD | UBE3C-008 | chr7_157232445_+ | 4.98e-01 | 3.16e-01 | 2.28e+00 | 2.29e-02 | 3.53e-02 | 1.82e-01 |
| COAD | UBE3C-008 | chr7_157232587_+ | 3.45e-01 | 2.77e-01 | 2.08e+00 | 3.79e-02 | 4.41e-02 | 6.88e-02 |
| COAD | UBE3C-008 | chr7_157232626_+ | 3.10e-01 | 1.75e-01 | 2.42e+00 | 1.57e-02 | 2.91e-02 | 1.36e-01 |
| STAD | UBE3C-008 | chr7_157232530_+ | 2.56e-01 | 3.24e-01 | -2.04e+00 | 4.09e-02 | 4.96e-02 | -6.76e-02 |
| STAD | UBE3C-008 | chr7_157235112_+ | 1.83e-01 | 2.43e-01 | -2.17e+00 | 3.03e-02 | 4.96e-02 | -5.96e-02 |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for UBE3C |
| TFs related to UBE3C. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| PAAD | ZNF418 | UBE3C | 4.62e+00 | 9.92e-01 | 3.46e+00 | 1.93e-03 | Male-biased |
| PAAD | ZNF79 | UBE3C | 4.21e+00 | 9.82e-01 | 3.31e+00 | 6.85e-03 | Male-biased |
| PAAD | ZNF879 | UBE3C | 4.29e+00 | 9.85e-01 | 3.35e+00 | 5.73e-03 | Male-biased |
| UBE3C related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for UBE3C |
| RBPs related to ES in UBE3C. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| UVM | ZCRB1 | exon_skip_472864 | 1.12e+01 | 2.29e-03 | 1.16e+01 | 9.97e-01 | Female-biased |
| THYM | PABPC5 | exon_skip_472864 | 7.15e+00 | 9.13e-03 | 7.48e+00 | 9.80e-01 | Female-biased |
| COAD | IGF2BP2 | exon_skip_472838 | 7.68e+00 | 9.16e-03 | 8.02e+00 | 9.82e-01 | Female-biased |
| COAD | IGF2BP3 | exon_skip_472838 | 7.69e+00 | 9.02e-03 | 8.03e+00 | 9.83e-01 | Female-biased |
| COAD | KHDRBS2 | exon_skip_472838 | 7.44e+00 | 9.81e-03 | 7.77e+00 | 9.81e-01 | Female-biased |
| ESCA | PTBP1 | exon_skip_472877 | 7.24e+00 | 9.84e-01 | 6.69e+00 | 4.62e-03 | Male-biased |
| ESCA | ZC3H10 | exon_skip_472841 | 9.08e+00 | 1.65e-02 | 9.47e+00 | 9.81e-01 | Female-biased |
| READ | hnRNPK | exon_skip_472866 | 8.79e+00 | 1.16e-02 | 9.11e+00 | 9.85e-01 | Female-biased |
| READ | IGF2BP2 | exon_skip_472838 | 7.69e+00 | 1.13e-02 | 8.02e+00 | 9.80e-01 | Female-biased |
| READ | IGF2BP3 | exon_skip_472838 | 7.70e+00 | 1.13e-02 | 8.03e+00 | 9.80e-01 | Female-biased |
| READ | ZC3H10 | exon_skip_472841 | 9.57e+00 | 9.95e-01 | 9.11e+00 | 2.34e-03 | Male-biased |
| MESO | IGF2BP2 | exon_skip_472837 | 8.68e+00 | 8.15e-03 | 9.05e+00 | 9.87e-01 | Female-biased |
| MESO | IGF2BP3 | exon_skip_472837 | 8.65e+00 | 8.20e-03 | 9.01e+00 | 9.87e-01 | Female-biased |
| MESO | PABPC5 | exon_skip_472864 | 7.24e+00 | 8.84e-03 | 7.60e+00 | 9.81e-01 | Female-biased |
| MESO | ZC3H10 | exon_skip_472841 | 9.04e+00 | 4.70e-03 | 9.46e+00 | 9.92e-01 | Female-biased |
| GBM | HNRNPH2 | exon_skip_472868 | 5.96e+00 | 8.74e-04 | 6.54e+00 | 9.81e-01 | Female-biased |
| KIRC | PABPN1 | exon_skip_472877 | 7.62e+00 | 9.85e-01 | 7.27e+00 | 5.48e-03 | Male-biased |
| BLCA | HNRNPH2 | exon_skip_472868 | 6.08e+00 | 1.18e-03 | 6.66e+00 | 9.82e-01 | Female-biased |
| SARC | ZC3H10 | exon_skip_472841 | 9.10e+00 | 2.50e-03 | 9.62e+00 | 9.95e-01 | Female-biased |
| UBE3C related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs1076283 | chr7:149395916:A:G | - | 0.0609599574600782 | 0.0184910702514458 | LUAD | Female-baised eQTL |
| rs2727527 | chr7:151650376:A:C | - | 0.0453977636056503 | 0.0384637879691944 | LUAD | Female-baised eQTL |
| rs10272564 | chr7:149008398:G:A | - | 0.095575843412138 | 0.00542335829119724 | COAD | Female-baised eQTL |
| rs4727005 | chr7:149007777:C:T | - | 0.0939636844516561 | 0.00699779924518216 | COAD | Female-baised eQTL |
| rs3779039 | chr7:149013484:C:T | - | 0.092846662151949 | 0.00739621612522477 | COAD | Female-baised eQTL |
| rs6965440 | chr7:149023989:A:C | - | 0.0943888560147493 | 0.0117772327635955 | COAD | Female-baised eQTL |
| rs6464930 | chr7:149023814:C:T | - | 0.0932993423189938 | 0.0134267322987106 | COAD | Female-baised eQTL |
| rs112684174 | chr7:149024689:A:G | - | 0.0945923327096129 | 0.013826825695623 | COAD | Female-baised eQTL |
| rs112799047 | chr7:149024797:C:A | - | 0.0945923327096129 | 0.013826825695623 | COAD | Female-baised eQTL |
| rs10233906 | chr7:149025555:C:T | - | 0.0945923327096129 | 0.013826825695623 | COAD | Female-baised eQTL |
| rs112634954 | chr7:149024771:G:A | - | 0.0934900064667473 | 0.0156123432978186 | COAD | Female-baised eQTL |
| rs6944853 | chr7:149024089:G:A | - | 0.0871945565892848 | 0.0166647574080698 | COAD | Female-baised eQTL |
| rs9065 | chr7:149003757:C:T | - | 0.0971143004152644 | 0.0188549448459832 | COAD | Female-baised eQTL |
| rs6464929 | chr7:149020375:G:A | - | 0.0849489514114288 | 0.0216384683486201 | COAD | Female-baised eQTL |
| rs66691097 | chr7:149008851:C:G | - | 0.0850782144553706 | 0.021824933312126 | COAD | Female-baised eQTL |
| rs11980538 | chr7:149009071:T:C | - | 0.0850782144553706 | 0.021824933312126 | COAD | Female-baised eQTL |
| rs13247593 | chr7:149026177:A:G | - | 0.087755077786679 | 0.0243968510913959 | COAD | Female-baised eQTL |
| rs28463009 | chr7:149011111:G:C | - | 0.0875441543065516 | 0.024962611314074 | COAD | Female-baised eQTL |
| rs4727006 | chr7:149007843:A:G | - | 0.0834930957932154 | 0.0269267589816137 | COAD | Female-baised eQTL |
| rs7805319 | chr7:148999077:C:T | - | 0.0949609104196193 | 0.0281274822581055 | COAD | Female-baised eQTL |
| rs7809055 | chr7:148999211:C:G | - | 0.0949609104196193 | 0.0281274822581055 | COAD | Female-baised eQTL |
| rs6464928 | chr7:149002830:G:A | - | 0.0837254116556981 | 0.0315638411230416 | COAD | Female-baised eQTL |
| rs1052549 | chr7:149003450:A:C | - | 0.0837254116556981 | 0.0315638411230416 | COAD | Female-baised eQTL |
| rs6963547 | chr7:149022576:T:C | - | 0.0883632402566291 | 0.0344030032765691 | COAD | Female-baised eQTL |
| rs10085877 | chr7:149004554:G:C | - | 0.0856245753921194 | 0.0349569048440141 | COAD | Female-baised eQTL |
| rs10236808 | chr7:149001382:C:T | - | 0.0821463413083697 | 0.0377223685670631 | COAD | Female-baised eQTL |
| rs7795577 | chr7:149005394:A:G | - | 0.0813340208167656 | 0.0380685426072076 | COAD | Female-baised eQTL |
| rs28532077 | chr7:149005065:C:T | - | 0.0848194473767028 | 0.0393579066050331 | COAD | Female-baised eQTL |
| rs7781312 | chr7:149027144:A:T | - | 0.0845906862114828 | 0.0434008923743743 | COAD | Female-baised eQTL |
| rs1551926 | chr7:149022491:T:C | - | -0.0816419525929627 | 0.0446515669570901 | COAD | Female-baised eQTL |
| rs6958855 | chr7:149021946:T:A | - | 0.0844218934958099 | 0.0490069360330446 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs112857065 | chr7:155969463:G:A | - | 0.0819399634891449 | 0.0140502336880132 | LGG | Male-baised eQTL |
| rs6459976 | chr7:155969079:C:T | - | 0.0779454096477898 | 0.0277104401011616 | LGG | Male-baised eQTL |
| rs73181280 | chr7:157557966:A:T | - | 0.0528850009640663 | 0.013169484068171 | BLCA | Male-baised eQTL |
| rs113717500 | chr7:157563622:G:A | - | 0.0520859226240111 | 0.0152213211113888 | BLCA | Male-baised eQTL |
| rs4716758 | chr7:157566869:G:C | - | 0.0520859226240111 | 0.0152213211113888 | BLCA | Male-baised eQTL |
| rs373233384 | chr7:157563203:T:C | - | 0.0510069519181837 | 0.0226160038982506 | BLCA | Male-baised eQTL |
| rs2788495 | chr7:158803615:G:A | - | 0.0658125823919514 | 0.0329504514973191 | BLCA | Male-baised eQTL |
| rs10274893 | chr7:158491550:A:T | - | -0.0813673054762874 | 0.00304969885205211 | LUAD | Male-baised eQTL |
| rs10232620 | chr7:158534547:C:T | - | -0.0754462448609984 | 0.0136623659021655 | LUAD | Male-baised eQTL |
| rs10261281 | chr7:158534627:G:C | - | -0.0754462448609984 | 0.0136623659021655 | LUAD | Male-baised eQTL |
| rs10232983 | chr7:158534856:C:T | - | -0.0754377572893639 | 0.0136885597557878 | LUAD | Male-baised eQTL |
| rs4909238 | chr7:158532880:T:C | - | -0.0736497414557027 | 0.0144514706459515 | LUAD | Male-baised eQTL |
| rs10081191 | chr7:158530114:A:C | - | -0.0730971468193023 | 0.0150361379547944 | LUAD | Male-baised eQTL |
| rs12670231 | chr7:158532646:G:A | - | -0.0730971468193023 | 0.0150361379547944 | LUAD | Male-baised eQTL |
| rs4909239 | chr7:158533395:A:G | - | -0.0730971468193023 | 0.0150361379547944 | LUAD | Male-baised eQTL |
| rs12534193 | chr7:158530510:G:C | - | -0.07195704774163 | 0.0226618790916849 | LUAD | Male-baised eQTL |
| rs10265417 | chr7:158487897:C:T | - | -0.0700557453271992 | 0.0232156291362125 | LUAD | Male-baised eQTL |
| rs56083936 | chr7:158488793:C:G | - | -0.0705103163712704 | 0.0236616561859781 | LUAD | Male-baised eQTL |
| rs57121296 | chr7:158533599:G:A | - | -0.0720624580498128 | 0.0237540620827879 | LUAD | Male-baised eQTL |
| rs10225002 | chr7:158487943:T:C | - | -0.0700022821999673 | 0.0248390533511276 | LUAD | Male-baised eQTL |
| rs62481733 | chr7:155901270:C:T | - | 0.139369103699278 | 7.36221073680511e-05 | COAD | Male-baised eQTL |
| rs61577287 | chr7:155893664:A:G | - | 0.128139424028216 | 0.000303473179382604 | COAD | Male-baised eQTL |
| rs77365900 | chr7:155904365:G:A | - | 0.132616319595117 | 0.000697985622417369 | COAD | Male-baised eQTL |
| rs62481737 | chr7:155904723:C:T | - | 0.132616319595117 | 0.000697985622417369 | COAD | Male-baised eQTL |
| rs117464208 | chr7:155906279:G:T | - | 0.132843662649704 | 0.000934382388740903 | COAD | Male-baised eQTL |
| rs13246178 | chr7:154520093:G:T | - | 0.0678801680084515 | 0.00365059057014199 | COAD | Male-baised eQTL |
| rs73460109 | chr7:147783720:C:T | - | 0.116078747364028 | 0.00530101490283313 | COAD | Male-baised eQTL |
| rs12113689 | chr7:147746400:G:A | - | 0.0998138328592371 | 0.0090907220310485 | COAD | Male-baised eQTL |
| rs143394879 | chr7:147734686:C:A | - | 0.0968053484240352 | 0.00983709520555581 | COAD | Male-baised eQTL |
| rs138749160 | chr7:147734799:T:C | - | 0.0968053484240352 | 0.00983709520555581 | COAD | Male-baised eQTL |
| rs926102 | chr7:153065831:G:A | - | -0.0558855038590025 | 0.0108191645848394 | COAD | Male-baised eQTL |
| rs59703369 | chr7:148468354:G:A | - | 0.109612408929782 | 0.0152602568059692 | COAD | Male-baised eQTL |
| rs75506728 | chr7:148468537:A:G | - | 0.109612408929782 | 0.0152602568059692 | COAD | Male-baised eQTL |
| rs1234356 | chr7:150686741:T:C | - | -0.0548213349746269 | 0.0155110044336208 | COAD | Male-baised eQTL |
| rs78586460 | chr7:155933774:A:T | - | 0.0873049563849816 | 0.0164056357859301 | COAD | Male-baised eQTL |
| rs150938970 | chr7:155934816:C:T | - | 0.0873049563849816 | 0.0164056357859301 | COAD | Male-baised eQTL |
| rs73475064 | chr7:147757698:G:T | - | 0.101729609397829 | 0.0177335385171068 | COAD | Male-baised eQTL |
| rs77328689 | chr7:147729420:A:G | - | 0.0963274023445395 | 0.0271136347394841 | COAD | Male-baised eQTL |
| rs75263336 | chr7:147730106:G:A | - | 0.0963274023445395 | 0.0271136347394841 | COAD | Male-baised eQTL |
| rs73475065 | chr7:147758096:C:G | - | 0.0939815535727447 | 0.0303117799113196 | COAD | Male-baised eQTL |
| rs62490366 | chr7:150677653:A:G | - | 0.051072056244325 | 0.0304060723454548 | COAD | Male-baised eQTL |
| rs112981485 | chr7:147734334:G:A | - | 0.0936898585636267 | 0.0310590659475942 | COAD | Male-baised eQTL |
| rs6962148 | chr7:148467246:T:C | - | 0.0944566648559461 | 0.034426171091476 | COAD | Male-baised eQTL |
| rs6976253 | chr7:148467845:G:A | - | 0.0944566648559461 | 0.034426171091476 | COAD | Male-baised eQTL |
| rs9640245 | chr7:147791538:G:A | - | 0.0907341687018223 | 0.0371424396734037 | COAD | Male-baised eQTL |
| rs73460125 | chr7:147792352:C:T | - | 0.0907341687018223 | 0.0371424396734037 | COAD | Male-baised eQTL |
| rs56279394 | chr7:150678124:C:T | - | 0.0495194385196232 | 0.0393790881118196 | COAD | Male-baised eQTL |
| rs56138121 | chr7:150678313:G:T | - | 0.0495194385196232 | 0.0393790881118196 | COAD | Male-baised eQTL |
| rs62477167 | chr7:154561879:C:G | - | 0.0595171296921245 | 0.0405098162628959 | COAD | Male-baised eQTL |
| rs73460131 | chr7:147797663:T:C | - | 0.0898405574028801 | 0.0405380048631966 | COAD | Male-baised eQTL |
| rs73460128 | chr7:147792745:A:T | - | 0.0897883052940582 | 0.0406419244602651 | COAD | Male-baised eQTL |
| rs12056208 | chr7:147728374:T:C | - | 0.090759848281678 | 0.0415686809771258 | COAD | Male-baised eQTL |
| rs954395 | chr7:150673167:A:G | - | 0.0486971082489253 | 0.0447838764701683 | COAD | Male-baised eQTL |
| rs62477165 | chr7:154558404:T:C | - | 0.0597917203657391 | 0.0454886877194373 | COAD | Male-baised eQTL |
| rs141832123 | chr7:147736064:A:G | - | 0.0883608786801065 | 0.0466016539338646 | COAD | Male-baised eQTL |
| rs12112564 | chr7:147747980:A:G | - | 0.0878447684500859 | 0.0486898085763718 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_472831 | chr7:157169047:157169122 | In-frame | rs1184671 | chr7:157288893:T:C | Distant downstream | 0.0539788008542694 | 0.00805170482200301 | HNSC | Female-baised sQTL |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of UBE3C |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000009335 | UBE3C | C0087031 | Juvenile-Onset Still Disease | 1 | CTD_human |
| ENSG00000009335 | UBE3C | C3495559 | Juvenile arthritis | 1 | CTD_human |
| ENSG00000009335 | UBE3C | C3714758 | Juvenile psoriatic arthritis | 1 | CTD_human |
| ENSG00000009335 | UBE3C | C4552091 | Polyarthritis, Juvenile, Rheumatoid Factor Negative | 1 | CTD_human |
| ENSG00000009335 | UBE3C | C4704862 | Polyarthritis, Juvenile, Rheumatoid Factor Positive | 1 | CTD_human |
