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Editing gene: SEC16A (CAeditome ID:9919)

Gene summary for SEC16A

Gene summary

Gene information	Gene symbol	SEC16A
	Gene ID	9919
	Gene name	SEC16 homolog A, endoplasmic reticulum export factor
	Synonyms	KIAA0310\|SEC16L\|p250
	Cytomap	9q34.3
	Type of gene	protein-coding
	Description	protein transport protein Sec16Aprotein SEC16 homolog A
	Modification date	20210518
	UniProtAcc	O15027
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
SEC16A	GO:0007029	Protein transport protein Sec16A	21768384
SEC16A	GO:0034976	Protein transport protein Sec16A	28067262
SEC16A	GO:0005783	Protein transport protein Sec16A	0000052
SEC16A	GO:0005789	Protein transport protein Sec16A	29300766
SEC16A	GO:0005794	Protein transport protein Sec16A	0000052
SEC16A	GO:0005829	Protein transport protein Sec16A	17428803
SEC16A	GO:0005829	Protein transport protein Sec16A	21768384
SEC16A	GO:0031090	Protein transport protein Sec16A	17428803
SEC16A	GO:0070971	Protein transport protein Sec16A	19638414
SEC16A	GO:0070971	Protein transport protein Sec16A	22355596
SEC16A	GO:0070971	Protein transport protein Sec16A	25201882
SEC16A	GO:0070971	Protein transport protein Sec16A	28067262

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RNA A-to-I events for SEC16A

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000148396.17

RNA A-to-I editing events in Cancer.

CAediting_722558(136441103, -), CAediting_722559(136441114, -), CAediting_722560(136441145, -), CAediting_722561(136441166, -), CAediting_722562(136441171, -), CAediting_722563(136441194, -), CAediting_722564(136441406, -), CAediting_722565(136441409, -), CAediting_722566(136441411, -), CAediting_722567(136444652, -), CAediting_722568(136444713, -), CAediting_722569(136444766, -), CAediting_722570(136446182, -), CAediting_722571(136446191, -), CAediting_722572(136449336, -), CAediting_722573(136449388, -), CAediting_722574(136449490, -), CAediting_722575(136450104, -), CAediting_722576(136450128, -), CAediting_722577(136458004, -), CAediting_722578(136458049, -), CAediting_722579(136458072, -), CAediting_722580(136458084, -), CAediting_722581(136458107, -), CAediting_722582(136458116, -), CAediting_722583(136458201, -), CAediting_722584(136458202, -), CAediting_722585(136458219, -), CAediting_722586(136458220, -), CAediting_722587(136458228, -), CAediting_722588(136458241, -), CAediting_722589(136458516, -), CAediting_722590(136458528, -), CAediting_722591(136458551, -), CAediting_722592(136458597, -), CAediting_722593(136458826, -), CAediting_722594(136458846, -), CAediting_722595(136458896, -), CAediting_722596(136468923, -), CAediting_722597(136469000, -), CAediting_722598(136469009, -), CAediting_722599(136469013, -), CAediting_722600(136469491, -), CAediting_722601(136469581, -), CAediting_722602(136478733, -), CAediting_722603(136479450, -), CAediting_722604(136479464, -), CAediting_722605(136479477, -), CAediting_722606(136479501, -), CAediting_722607(136479757, -), CAediting_722608(136479769, -), CAediting_722609(136479770, -), CAediting_722610(136479771, -), CAediting_722611(136479805, -), CAediting_722612(136479880, -), CAediting_722613(136479902, -), CAediting_722614(136479919, -), CAediting_722615(136479940, -), CAediting_722616(136479945, -), CAediting_722617(136479954, -), CAediting_722618(136479988, -), CAediting_722619(136479994, -), CAediting_722620(136481264, -), CAediting_722621(136481300, -), CAediting_722622(136481367, -), CAediting_722623(136481410, -), CAediting_722624(136481411, -),

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RNA editing positional annotations for SEC16A using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_722558	chr9_136441103_-	ncRNA_exonic
CAediting_722559	chr9_136441114_-	ncRNA_exonic
CAediting_722560	chr9_136441145_-	ncRNA_exonic
CAediting_722561	chr9_136441166_-	ncRNA_exonic
CAediting_722562	chr9_136441171_-	ncRNA_exonic
CAediting_722563	chr9_136441194_-	ncRNA_exonic
CAediting_722564	chr9_136441406_-	ncRNA_exonic
CAediting_722565	chr9_136441409_-	ncRNA_exonic
CAediting_722566	chr9_136441411_-	ncRNA_exonic
CAediting_722567	chr9_136444652_-	intronic
CAediting_722568	chr9_136444713_-	intronic
CAediting_722569	chr9_136444766_-	intronic
CAediting_722570	chr9_136446182_-	intronic
CAediting_722571	chr9_136446191_-	intronic
CAediting_722572	chr9_136449336_-	intronic
CAediting_722573	chr9_136449388_-	intronic
CAediting_722574	chr9_136449490_-	intronic
CAediting_722575	chr9_136450104_-	intronic
CAediting_722576	chr9_136450128_-	intronic
CAediting_722577	chr9_136458004_-	intronic
CAediting_722578	chr9_136458049_-	intronic
CAediting_722579	chr9_136458072_-	intronic
CAediting_722580	chr9_136458084_-	intronic
CAediting_722581	chr9_136458107_-	intronic
CAediting_722582	chr9_136458116_-	intronic
CAediting_722583	chr9_136458201_-	intronic
CAediting_722584	chr9_136458202_-	intronic
CAediting_722585	chr9_136458219_-	intronic
CAediting_722586	chr9_136458220_-	intronic
CAediting_722587	chr9_136458228_-	intronic
CAediting_722588	chr9_136458241_-	intronic
CAediting_722589	chr9_136458516_-	intronic
CAediting_722590	chr9_136458528_-	intronic
CAediting_722591	chr9_136458551_-	intronic
CAediting_722592	chr9_136458597_-	intronic
CAediting_722593	chr9_136458826_-	intronic
CAediting_722594	chr9_136458846_-	intronic
CAediting_722595	chr9_136458896_-	intronic
CAediting_722596	chr9_136468923_-	intronic
CAediting_722597	chr9_136469000_-	intronic
CAediting_722598	chr9_136469009_-	intronic
CAediting_722599	chr9_136469013_-	intronic
CAediting_722600	chr9_136469491_-	intronic
CAediting_722601	chr9_136469581_-	intronic
CAediting_722602	chr9_136478733_-	intronic
CAediting_722603	chr9_136479450_-	intronic
CAediting_722604	chr9_136479464_-	intronic
CAediting_722605	chr9_136479477_-	intronic
CAediting_722606	chr9_136479501_-	intronic
CAediting_722607	chr9_136479757_-	intronic
CAediting_722608	chr9_136479769_-	intronic
CAediting_722609	chr9_136479770_-	intronic
CAediting_722610	chr9_136479771_-	intronic
CAediting_722611	chr9_136479805_-	intronic
CAediting_722612	chr9_136479880_-	intronic
CAediting_722613	chr9_136479902_-	intronic
CAediting_722614	chr9_136479919_-	intronic
CAediting_722615	chr9_136479940_-	intronic
CAediting_722616	chr9_136479945_-	intronic
CAediting_722617	chr9_136479954_-	intronic
CAediting_722618	chr9_136479988_-	intronic
CAediting_722619	chr9_136479994_-	intronic
CAediting_722620	chr9_136481264_-	intronic
CAediting_722621	chr9_136481300_-	intronic
CAediting_722622	chr9_136481367_-	intronic
CAediting_722623	chr9_136481410_-	intronic
CAediting_722624	chr9_136481411_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_722567	chr9_136444652_-	SINE	Alu	AluSp
CAediting_722568	chr9_136444713_-	SINE	Alu	AluSp
CAediting_722569	chr9_136444766_-	SINE	Alu	AluSp
CAediting_722570	chr9_136446182_-	SINE	Alu	AluSx1
CAediting_722571	chr9_136446191_-	SINE	Alu	AluSx1
CAediting_722572	chr9_136449336_-	SINE	Alu	AluSg7
CAediting_722573	chr9_136449388_-	SINE	Alu	AluSg7
CAediting_722574	chr9_136449490_-	SINE	Alu	AluSg7
CAediting_722575	chr9_136450104_-	SINE	Alu	AluSx1
CAediting_722576	chr9_136450128_-	SINE	Alu	AluSx1
CAediting_722577	chr9_136458004_-	SINE	Alu	AluJb
CAediting_722578	chr9_136458049_-	SINE	Alu	AluJb
CAediting_722579	chr9_136458072_-	SINE	Alu	AluJb
CAediting_722580	chr9_136458084_-	SINE	Alu	AluJb
CAediting_722581	chr9_136458107_-	SINE	Alu	AluJb
CAediting_722582	chr9_136458116_-	SINE	Alu	AluJb
CAediting_722583	chr9_136458201_-	SINE	Alu	AluJb
CAediting_722584	chr9_136458202_-	SINE	Alu	AluJb
CAediting_722585	chr9_136458219_-	SINE	Alu	AluJb
CAediting_722586	chr9_136458220_-	SINE	Alu	AluJb
CAediting_722587	chr9_136458228_-	SINE	Alu	AluJb
CAediting_722588	chr9_136458241_-	SINE	Alu	AluJb
CAediting_722589	chr9_136458516_-	SINE	Alu	AluY
CAediting_722590	chr9_136458528_-	SINE	Alu	AluY
CAediting_722591	chr9_136458551_-	SINE	Alu	AluY
CAediting_722592	chr9_136458597_-	SINE	Alu	AluY
CAediting_722593	chr9_136458826_-	SINE	Alu	AluJb
CAediting_722594	chr9_136458846_-	SINE	Alu	AluJb
CAediting_722595	chr9_136458896_-	SINE	Alu	AluJb
CAediting_722596	chr9_136468923_-	SINE	Alu	AluJb
CAediting_722597	chr9_136469000_-	SINE	Alu	AluJb
CAediting_722598	chr9_136469009_-	SINE	Alu	AluJb
CAediting_722599	chr9_136469013_-	SINE	Alu	AluJb
CAediting_722600	chr9_136469491_-	SINE	Alu	AluJo
CAediting_722601	chr9_136469581_-	SINE	Alu	AluJo
CAediting_722602	chr9_136478733_-	SINE	Alu	AluJo
CAediting_722603	chr9_136479450_-	SINE	Alu	AluY
CAediting_722604	chr9_136479464_-	SINE	Alu	AluY
CAediting_722605	chr9_136479477_-	SINE	Alu	AluY
CAediting_722606	chr9_136479501_-	SINE	Alu	AluY
CAediting_722607	chr9_136479757_-	SINE	Alu	AluJb
CAediting_722608	chr9_136479769_-	SINE	Alu	AluJb
CAediting_722609	chr9_136479770_-	SINE	Alu	AluJb
CAediting_722610	chr9_136479771_-	SINE	Alu	AluJb
CAediting_722611	chr9_136479805_-	SINE	Alu	AluJb
CAediting_722612	chr9_136479880_-	SINE	Alu	AluJb
CAediting_722613	chr9_136479902_-	SINE	Alu	AluJb
CAediting_722614	chr9_136479919_-	SINE	Alu	AluJb
CAediting_722615	chr9_136479940_-	SINE	Alu	AluJb
CAediting_722616	chr9_136479945_-	SINE	Alu	AluJb
CAediting_722617	chr9_136479954_-	SINE	Alu	AluJb
CAediting_722618	chr9_136479988_-	SINE	Alu	AluJb
CAediting_722619	chr9_136479994_-	SINE	Alu	AluJb
CAediting_722620	chr9_136481264_-	SINE	Alu	AluYe6
CAediting_722621	chr9_136481300_-	SINE	Alu	AluYe6
CAediting_722622	chr9_136481367_-	SINE	Alu	AluYe6
CAediting_722623	chr9_136481410_-	SINE	Alu	AluYe6
CAediting_722624	chr9_136481411_-	SINE	Alu	AluYe6

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RNA A-to-I editing events in the alternative splicing sites for SEC16A

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000148396.17.SEC16A.

Correlation between RNA A-to-I editing and PSI for ENSG00000148396.17.SEC16A.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SEC16A

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for SEC16A

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for SEC16A

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000313050	hsa-miR-4743-5p	136441100	136441106	7mer-m8	136441099	136441121	146.00	-17.61
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000290037	hsa-miR-4743-5p	136441100	136441106	7mer-m8	136441099	136441121	146.00	-17.61
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000277537	hsa-miR-4743-5p	136441100	136441106	7mer-m8	136441099	136441121	146.00	-17.61
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000453963	hsa-miR-4743-5p	136441100	136441106	7mer-m8	136441099	136441121	146.00	-17.61
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000371706	hsa-miR-4743-5p	136441100	136441106	7mer-m8	136441099	136441121	146.00	-17.61
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000313084	hsa-miR-4743-5p	136441100	136441106	7mer-m8	136441099	136441121	146.00	-17.61
CAediting_722559	chr9_136441114_-	ENSG00000148396.17	ENST00000313050	hsa-miR-4772-3p	136441113	136441120	8mer-1a	136441113	136441134	140.00	-9.29
CAediting_722559	chr9_136441114_-	ENSG00000148396.17	ENST00000313050	hsa-miR-593-3p	136441110	136441116	7mer-m8	136441109	136441127	146.00	-19.42
CAediting_722559	chr9_136441114_-	ENSG00000148396.17	ENST00000290037	hsa-miR-4772-3p	136441113	136441120	8mer-1a	136441113	136441134	140.00	-9.29
CAediting_722559	chr9_136441114_-	ENSG00000148396.17	ENST00000290037	hsa-miR-593-3p	136441110	136441116	7mer-m8	136441109	136441127	146.00	-19.42
CAediting_722559	chr9_136441114_-	ENSG00000148396.17	ENST00000277537	hsa-miR-4772-3p	136441113	136441120	8mer-1a	136441113	136441134	140.00	-9.29
CAediting_722559	chr9_136441114_-	ENSG00000148396.17	ENST00000277537	hsa-miR-593-3p	136441110	136441116	7mer-m8	136441109	136441127	146.00	-19.42
CAediting_722559	chr9_136441114_-	ENSG00000148396.17	ENST00000453963	hsa-miR-4772-3p	136441113	136441120	8mer-1a	136441113	136441134	140.00	-9.29
CAediting_722559	chr9_136441114_-	ENSG00000148396.17	ENST00000453963	hsa-miR-593-3p	136441110	136441116	7mer-m8	136441109	136441127	146.00	-19.42
CAediting_722559	chr9_136441114_-	ENSG00000148396.17	ENST00000371706	hsa-miR-4772-3p	136441113	136441120	8mer-1a	136441113	136441134	140.00	-9.29
CAediting_722559	chr9_136441114_-	ENSG00000148396.17	ENST00000371706	hsa-miR-593-3p	136441110	136441116	7mer-m8	136441109	136441127	146.00	-19.42
CAediting_722559	chr9_136441114_-	ENSG00000148396.17	ENST00000313084	hsa-miR-4772-3p	136441113	136441120	8mer-1a	136441113	136441134	140.00	-9.29
CAediting_722559	chr9_136441114_-	ENSG00000148396.17	ENST00000313084	hsa-miR-593-3p	136441110	136441116	7mer-m8	136441109	136441127	146.00	-19.42
CAediting_722560	chr9_136441145_-	ENSG00000148396.17	ENST00000313050	hsa-miR-3922-5p	136441145	136441151	7mer-m8	136441144	136441166	140.00	-16.06
CAediting_722560	chr9_136441145_-	ENSG00000148396.17	ENST00000290037	hsa-miR-3922-5p	136441145	136441151	7mer-m8	136441144	136441166	140.00	-16.06
CAediting_722560	chr9_136441145_-	ENSG00000148396.17	ENST00000277537	hsa-miR-3922-5p	136441145	136441151	7mer-m8	136441144	136441166	140.00	-16.06
CAediting_722560	chr9_136441145_-	ENSG00000148396.17	ENST00000453963	hsa-miR-3922-5p	136441145	136441151	7mer-m8	136441144	136441166	140.00	-16.06
CAediting_722560	chr9_136441145_-	ENSG00000148396.17	ENST00000371706	hsa-miR-3922-5p	136441145	136441151	7mer-m8	136441144	136441166	140.00	-16.06
CAediting_722560	chr9_136441145_-	ENSG00000148396.17	ENST00000313084	hsa-miR-3922-5p	136441145	136441151	7mer-m8	136441144	136441166	140.00	-16.06
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000313050	hsa-miR-10392-3p	136441190	136441196	7mer-m8	136441189	136441212	152.00	-27.14
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000313050	hsa-miR-4749-3p	136441192	136441198	7mer-m8	136441191	136441210	140.00	-14.91
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000313050	hsa-miR-6795-3p	136441193	136441199	7mer-m8	136441192	136441212	140.00	-15.41
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000290037	hsa-miR-10392-3p	136441190	136441196	7mer-m8	136441189	136441212	152.00	-27.14
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000290037	hsa-miR-4749-3p	136441192	136441198	7mer-m8	136441191	136441210	140.00	-14.91
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000290037	hsa-miR-6795-3p	136441193	136441199	7mer-m8	136441192	136441212	140.00	-15.41
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000277537	hsa-miR-10392-3p	136441190	136441196	7mer-m8	136441189	136441212	152.00	-27.14
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000277537	hsa-miR-4749-3p	136441192	136441198	7mer-m8	136441191	136441210	140.00	-14.91
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000277537	hsa-miR-6795-3p	136441193	136441199	7mer-m8	136441192	136441212	140.00	-15.41
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000453963	hsa-miR-10392-3p	136441190	136441196	7mer-m8	136441189	136441212	152.00	-27.14
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000453963	hsa-miR-4749-3p	136441192	136441198	7mer-m8	136441191	136441210	140.00	-14.91
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000453963	hsa-miR-6795-3p	136441193	136441199	7mer-m8	136441192	136441212	140.00	-15.41
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000371706	hsa-miR-10392-3p	136441190	136441196	7mer-m8	136441189	136441212	152.00	-27.14
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000371706	hsa-miR-4749-3p	136441192	136441198	7mer-m8	136441191	136441210	140.00	-14.91
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000371706	hsa-miR-6795-3p	136441193	136441199	7mer-m8	136441192	136441212	140.00	-15.41
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000313084	hsa-miR-10392-3p	136441190	136441196	7mer-m8	136441189	136441212	152.00	-27.14
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000313084	hsa-miR-4749-3p	136441192	136441198	7mer-m8	136441191	136441210	140.00	-14.91
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000313084	hsa-miR-6795-3p	136441193	136441199	7mer-m8	136441192	136441212	140.00	-15.41
CAediting_722564	chr9_136441406_-	ENSG00000148396.17	ENST00000313050	hsa-miR-10398-5p	136441400	136441407	8mer-1a	136441400	136441420	149.00	-18.76
CAediting_722564	chr9_136441406_-	ENSG00000148396.17	ENST00000313050	hsa-miR-146b-3p	136441406	136441412	7mer-m8	136441405	136441429	159.00	-34.23
CAediting_722564	chr9_136441406_-	ENSG00000148396.17	ENST00000290037	hsa-miR-10398-5p	136441400	136441407	8mer-1a	136441400	136441420	149.00	-18.76
CAediting_722564	chr9_136441406_-	ENSG00000148396.17	ENST00000290037	hsa-miR-146b-3p	136441406	136441412	7mer-m8	136441405	136441429	159.00	-34.23
CAediting_722564	chr9_136441406_-	ENSG00000148396.17	ENST00000277537	hsa-miR-10398-5p	136441400	136441407	8mer-1a	136441400	136441420	149.00	-18.76
CAediting_722564	chr9_136441406_-	ENSG00000148396.17	ENST00000277537	hsa-miR-146b-3p	136441406	136441412	7mer-m8	136441405	136441429	159.00	-34.23
CAediting_722564	chr9_136441406_-	ENSG00000148396.17	ENST00000453963	hsa-miR-10398-5p	136441400	136441407	8mer-1a	136441400	136441420	149.00	-18.76
CAediting_722564	chr9_136441406_-	ENSG00000148396.17	ENST00000453963	hsa-miR-146b-3p	136441406	136441412	7mer-m8	136441405	136441429	159.00	-34.23
CAediting_722564	chr9_136441406_-	ENSG00000148396.17	ENST00000371706	hsa-miR-10398-5p	136441400	136441407	8mer-1a	136441400	136441420	149.00	-18.76
CAediting_722564	chr9_136441406_-	ENSG00000148396.17	ENST00000371706	hsa-miR-146b-3p	136441406	136441412	7mer-m8	136441405	136441429	159.00	-34.23
CAediting_722564	chr9_136441406_-	ENSG00000148396.17	ENST00000313084	hsa-miR-10398-5p	136441400	136441407	8mer-1a	136441400	136441420	149.00	-18.76
CAediting_722564	chr9_136441406_-	ENSG00000148396.17	ENST00000313084	hsa-miR-146b-3p	136441406	136441412	7mer-m8	136441405	136441429	159.00	-34.23
CAediting_722565	chr9_136441409_-	ENSG00000148396.17	ENST00000313050	hsa-miR-132-5p	136441408	136441414	7mer-m8	136441407	136441427	141.00	-17.64
CAediting_722565	chr9_136441409_-	ENSG00000148396.17	ENST00000290037	hsa-miR-132-5p	136441408	136441414	7mer-m8	136441407	136441427	141.00	-17.64
CAediting_722565	chr9_136441409_-	ENSG00000148396.17	ENST00000277537	hsa-miR-132-5p	136441408	136441414	7mer-m8	136441407	136441427	141.00	-17.64
CAediting_722565	chr9_136441409_-	ENSG00000148396.17	ENST00000453963	hsa-miR-132-5p	136441408	136441414	7mer-m8	136441407	136441427	141.00	-17.64
CAediting_722565	chr9_136441409_-	ENSG00000148396.17	ENST00000371706	hsa-miR-132-5p	136441408	136441414	7mer-m8	136441407	136441427	141.00	-17.64
CAediting_722565	chr9_136441409_-	ENSG00000148396.17	ENST00000313084	hsa-miR-132-5p	136441408	136441414	7mer-m8	136441407	136441427	141.00	-17.64
CAediting_722566	chr9_136441411_-	ENSG00000148396.17	ENST00000313050	hsa-miR-6820-5p	136441409	136441416	8mer-1a	136441409	136441427	154.00	-24.03
CAediting_722566	chr9_136441411_-	ENSG00000148396.17	ENST00000290037	hsa-miR-6820-5p	136441409	136441416	8mer-1a	136441409	136441427	154.00	-24.03
CAediting_722566	chr9_136441411_-	ENSG00000148396.17	ENST00000277537	hsa-miR-6820-5p	136441409	136441416	8mer-1a	136441409	136441427	154.00	-24.03
CAediting_722566	chr9_136441411_-	ENSG00000148396.17	ENST00000453963	hsa-miR-6820-5p	136441409	136441416	8mer-1a	136441409	136441427	154.00	-24.03
CAediting_722566	chr9_136441411_-	ENSG00000148396.17	ENST00000371706	hsa-miR-6820-5p	136441409	136441416	8mer-1a	136441409	136441427	154.00	-24.03
CAediting_722566	chr9_136441411_-	ENSG00000148396.17	ENST00000313084	hsa-miR-6820-5p	136441409	136441416	8mer-1a	136441409	136441427	154.00	-24.03

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000313050	hsa-miR-3129-3p	136441168	136441174	7mer-m8	136441167	136441188	145	-7.99
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000313050	hsa-miR-4268	136441192	136441198	7mer-m8	136441191	136441211	140	-21.65
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000313050	hsa-miR-4430	136441100	136441106	7mer-m8	136441099	136441113	143	-20.82
CAediting_722559	chr9_136441114_-	ENSG00000148396.17	ENST00000313050	hsa-miR-450b-5p	136441113	136441119	7mer-m8	136441112	136441133	148	-9.93
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000313050	hsa-miR-485-5p	136441097	136441104	8mer-1a	136441097	136441118	150	-19.87
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000313050	hsa-miR-5583-5p	136441168	136441174	7mer-m8	136441167	136441188	140	-10.55
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000313050	hsa-miR-5583-5p	136441168	136441174	7mer-m8	136441167	136441188	140	-10.55
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000313050	hsa-miR-6079	136441103	136441109	7mer-m8	136441102	136441125	146	-16.82
CAediting_722564	chr9_136441406_-	ENSG00000148396.17	ENST00000313050	hsa-miR-6845-3p	136441403	136441409	7mer-m8	136441402	136441422	140	-16.15
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000313050	hsa-miR-6884-5p	136441097	136441104	8mer-1a	136441097	136441118	152	-21.23
CAediting_722561	chr9_136441166_-	ENSG00000148396.17	ENST00000313050	hsa-miR-7158-3p	136441166	136441172	7mer-m8	136441165	136441185	145	-12.12
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000313050	hsa-miR-7158-3p	136441166	136441172	7mer-m8	136441165	136441185	145	-12.12
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000290037	hsa-miR-3129-3p	136441168	136441174	7mer-m8	136441167	136441188	145	-7.99
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000290037	hsa-miR-4268	136441192	136441198	7mer-m8	136441191	136441211	140	-21.65
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000290037	hsa-miR-4430	136441100	136441106	7mer-m8	136441099	136441113	143	-20.82
CAediting_722559	chr9_136441114_-	ENSG00000148396.17	ENST00000290037	hsa-miR-450b-5p	136441113	136441119	7mer-m8	136441112	136441133	148	-9.93
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000290037	hsa-miR-485-5p	136441097	136441104	8mer-1a	136441097	136441118	150	-19.87
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000290037	hsa-miR-5583-5p	136441168	136441174	7mer-m8	136441167	136441188	140	-10.55
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000290037	hsa-miR-5583-5p	136441168	136441174	7mer-m8	136441167	136441188	140	-10.55
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000290037	hsa-miR-6079	136441103	136441109	7mer-m8	136441102	136441125	146	-16.82
CAediting_722564	chr9_136441406_-	ENSG00000148396.17	ENST00000290037	hsa-miR-6845-3p	136441403	136441409	7mer-m8	136441402	136441422	140	-16.15
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000290037	hsa-miR-6884-5p	136441097	136441104	8mer-1a	136441097	136441118	152	-21.23
CAediting_722561	chr9_136441166_-	ENSG00000148396.17	ENST00000290037	hsa-miR-7158-3p	136441166	136441172	7mer-m8	136441165	136441185	145	-12.12
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000290037	hsa-miR-7158-3p	136441166	136441172	7mer-m8	136441165	136441185	145	-12.12
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000277537	hsa-miR-3129-3p	136441168	136441174	7mer-m8	136441167	136441188	145	-7.99
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000277537	hsa-miR-4268	136441192	136441198	7mer-m8	136441191	136441211	140	-21.65
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000277537	hsa-miR-4430	136441100	136441106	7mer-m8	136441099	136441113	143	-20.82
CAediting_722559	chr9_136441114_-	ENSG00000148396.17	ENST00000277537	hsa-miR-450b-5p	136441113	136441119	7mer-m8	136441112	136441133	148	-9.93
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000277537	hsa-miR-485-5p	136441097	136441104	8mer-1a	136441097	136441118	150	-19.87
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000277537	hsa-miR-5583-5p	136441168	136441174	7mer-m8	136441167	136441188	140	-10.55
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000277537	hsa-miR-5583-5p	136441168	136441174	7mer-m8	136441167	136441188	140	-10.55
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000277537	hsa-miR-6079	136441103	136441109	7mer-m8	136441102	136441125	146	-16.82
CAediting_722564	chr9_136441406_-	ENSG00000148396.17	ENST00000277537	hsa-miR-6845-3p	136441403	136441409	7mer-m8	136441402	136441422	140	-16.15
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000277537	hsa-miR-6884-5p	136441097	136441104	8mer-1a	136441097	136441118	152	-21.23
CAediting_722561	chr9_136441166_-	ENSG00000148396.17	ENST00000277537	hsa-miR-7158-3p	136441166	136441172	7mer-m8	136441165	136441185	145	-12.12
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000277537	hsa-miR-7158-3p	136441166	136441172	7mer-m8	136441165	136441185	145	-12.12
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000453963	hsa-miR-3129-3p	136441168	136441174	7mer-m8	136441167	136441188	145	-7.99
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000453963	hsa-miR-4268	136441192	136441198	7mer-m8	136441191	136441211	140	-21.65
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000453963	hsa-miR-4430	136441100	136441106	7mer-m8	136441099	136441113	143	-20.82
CAediting_722559	chr9_136441114_-	ENSG00000148396.17	ENST00000453963	hsa-miR-450b-5p	136441113	136441119	7mer-m8	136441112	136441133	148	-9.93
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000453963	hsa-miR-485-5p	136441097	136441104	8mer-1a	136441097	136441118	150	-19.87
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000453963	hsa-miR-5583-5p	136441168	136441174	7mer-m8	136441167	136441188	140	-10.55
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000453963	hsa-miR-5583-5p	136441168	136441174	7mer-m8	136441167	136441188	140	-10.55
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000453963	hsa-miR-6079	136441103	136441109	7mer-m8	136441102	136441125	146	-16.82
CAediting_722564	chr9_136441406_-	ENSG00000148396.17	ENST00000453963	hsa-miR-6845-3p	136441403	136441409	7mer-m8	136441402	136441422	140	-16.15
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000453963	hsa-miR-6884-5p	136441097	136441104	8mer-1a	136441097	136441118	152	-21.23
CAediting_722561	chr9_136441166_-	ENSG00000148396.17	ENST00000453963	hsa-miR-7158-3p	136441166	136441172	7mer-m8	136441165	136441185	145	-12.12
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000453963	hsa-miR-7158-3p	136441166	136441172	7mer-m8	136441165	136441185	145	-12.12
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000371706	hsa-miR-3129-3p	136441168	136441174	7mer-m8	136441167	136441188	145	-7.99
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000371706	hsa-miR-4268	136441192	136441198	7mer-m8	136441191	136441211	140	-21.65
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000371706	hsa-miR-4430	136441100	136441106	7mer-m8	136441099	136441113	143	-20.82
CAediting_722559	chr9_136441114_-	ENSG00000148396.17	ENST00000371706	hsa-miR-450b-5p	136441113	136441119	7mer-m8	136441112	136441133	148	-9.93
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000371706	hsa-miR-485-5p	136441097	136441104	8mer-1a	136441097	136441118	150	-19.87
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000371706	hsa-miR-5583-5p	136441168	136441174	7mer-m8	136441167	136441188	140	-10.55
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000371706	hsa-miR-5583-5p	136441168	136441174	7mer-m8	136441167	136441188	140	-10.55
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000371706	hsa-miR-6079	136441103	136441109	7mer-m8	136441102	136441125	146	-16.82
CAediting_722564	chr9_136441406_-	ENSG00000148396.17	ENST00000371706	hsa-miR-6845-3p	136441403	136441409	7mer-m8	136441402	136441422	140	-16.15
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000371706	hsa-miR-6884-5p	136441097	136441104	8mer-1a	136441097	136441118	152	-21.23
CAediting_722561	chr9_136441166_-	ENSG00000148396.17	ENST00000371706	hsa-miR-7158-3p	136441166	136441172	7mer-m8	136441165	136441185	145	-12.12
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000371706	hsa-miR-7158-3p	136441166	136441172	7mer-m8	136441165	136441185	145	-12.12
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000313084	hsa-miR-3129-3p	136441168	136441174	7mer-m8	136441167	136441188	145	-7.99
CAediting_722563	chr9_136441194_-	ENSG00000148396.17	ENST00000313084	hsa-miR-4268	136441192	136441198	7mer-m8	136441191	136441211	140	-21.65
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000313084	hsa-miR-4430	136441100	136441106	7mer-m8	136441099	136441113	143	-20.82
CAediting_722559	chr9_136441114_-	ENSG00000148396.17	ENST00000313084	hsa-miR-450b-5p	136441113	136441119	7mer-m8	136441112	136441133	148	-9.93
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000313084	hsa-miR-485-5p	136441097	136441104	8mer-1a	136441097	136441118	150	-19.87
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000313084	hsa-miR-5583-5p	136441168	136441174	7mer-m8	136441167	136441188	140	-10.55
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000313084	hsa-miR-5583-5p	136441168	136441174	7mer-m8	136441167	136441188	140	-10.55
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000313084	hsa-miR-6079	136441103	136441109	7mer-m8	136441102	136441125	146	-16.82
CAediting_722564	chr9_136441406_-	ENSG00000148396.17	ENST00000313084	hsa-miR-6845-3p	136441403	136441409	7mer-m8	136441402	136441422	140	-16.15
CAediting_722558	chr9_136441103_-	ENSG00000148396.17	ENST00000313084	hsa-miR-6884-5p	136441097	136441104	8mer-1a	136441097	136441118	152	-21.23
CAediting_722561	chr9_136441166_-	ENSG00000148396.17	ENST00000313084	hsa-miR-7158-3p	136441166	136441172	7mer-m8	136441165	136441185	145	-12.12
CAediting_722562	chr9_136441171_-	ENSG00000148396.17	ENST00000313084	hsa-miR-7158-3p	136441166	136441172	7mer-m8	136441165	136441185	145	-12.12

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_980496	chr14_31014685_-	ENSG00000148396.17	ENST00000313050	hsa-miR-624-3p	136440653	136440659	7mer-m8	136440652	136440670	147	-17.78
CAediting_980496	chr14_31014685_-	ENSG00000148396.17	ENST00000290037	hsa-miR-624-3p	136440653	136440659	7mer-m8	136440652	136440670	147	-17.78
CAediting_980496	chr14_31014685_-	ENSG00000148396.17	ENST00000277537	hsa-miR-624-3p	136440653	136440659	7mer-m8	136440652	136440670	147	-17.78
CAediting_980496	chr14_31014685_-	ENSG00000148396.17	ENST00000453963	hsa-miR-624-3p	136440653	136440659	7mer-m8	136440652	136440670	147	-17.78
CAediting_980496	chr14_31014685_-	ENSG00000148396.17	ENST00000371706	hsa-miR-624-3p	136440653	136440659	7mer-m8	136440652	136440670	147	-17.78
CAediting_980496	chr14_31014685_-	ENSG00000148396.17	ENST00000313084	hsa-miR-624-3p	136440653	136440659	7mer-m8	136440652	136440670	147	-17.78
CAediting_1229415	chr17_67471547_+	ENSG00000148396.17	ENST00000313050	hsa-miR-548aa	136440417	136440423	7mer-m8	136440416	136440441	152	-10.4
CAediting_228905	chr2_188297554_+	ENSG00000148396.17	ENST00000313050	hsa-miR-561-3p	136440584	136440590	7mer-m8	136440583	136440604	155	-10.41
CAediting_442554	chr5_154685830_+	ENSG00000148396.17	ENST00000313050	hsa-miR-1303	136441370	136441376	7mer-m8	136441369	136441387	152	-20.87
CAediting_524911	chr7_5495852_-	ENSG00000148396.17	ENST00000313050	hsa-miR-589-3p	136441273	136441279	7mer-m8	136441272	136441295	140	-13.73
CAediting_1229415	chr17_67471547_+	ENSG00000148396.17	ENST00000290037	hsa-miR-548aa	136440417	136440423	7mer-m8	136440416	136440441	152	-10.4
CAediting_228905	chr2_188297554_+	ENSG00000148396.17	ENST00000290037	hsa-miR-561-3p	136440584	136440590	7mer-m8	136440583	136440604	155	-10.41
CAediting_442554	chr5_154685830_+	ENSG00000148396.17	ENST00000290037	hsa-miR-1303	136441370	136441376	7mer-m8	136441369	136441387	152	-20.87
CAediting_524911	chr7_5495852_-	ENSG00000148396.17	ENST00000290037	hsa-miR-589-3p	136441273	136441279	7mer-m8	136441272	136441295	140	-13.73
CAediting_1229415	chr17_67471547_+	ENSG00000148396.17	ENST00000277537	hsa-miR-548aa	136440417	136440423	7mer-m8	136440416	136440441	152	-10.4
CAediting_228905	chr2_188297554_+	ENSG00000148396.17	ENST00000277537	hsa-miR-561-3p	136440584	136440590	7mer-m8	136440583	136440604	155	-10.41
CAediting_442554	chr5_154685830_+	ENSG00000148396.17	ENST00000277537	hsa-miR-1303	136441370	136441376	7mer-m8	136441369	136441387	152	-20.87
CAediting_524911	chr7_5495852_-	ENSG00000148396.17	ENST00000277537	hsa-miR-589-3p	136441273	136441279	7mer-m8	136441272	136441295	140	-13.73
CAediting_1229415	chr17_67471547_+	ENSG00000148396.17	ENST00000453963	hsa-miR-548aa	136440417	136440423	7mer-m8	136440416	136440441	152	-10.4
CAediting_228905	chr2_188297554_+	ENSG00000148396.17	ENST00000453963	hsa-miR-561-3p	136440584	136440590	7mer-m8	136440583	136440604	155	-10.41
CAediting_442554	chr5_154685830_+	ENSG00000148396.17	ENST00000453963	hsa-miR-1303	136441370	136441376	7mer-m8	136441369	136441387	152	-20.87
CAediting_524911	chr7_5495852_-	ENSG00000148396.17	ENST00000453963	hsa-miR-589-3p	136441273	136441279	7mer-m8	136441272	136441295	140	-13.73
CAediting_1229415	chr17_67471547_+	ENSG00000148396.17	ENST00000371706	hsa-miR-548aa	136440417	136440423	7mer-m8	136440416	136440441	152	-10.4
CAediting_228905	chr2_188297554_+	ENSG00000148396.17	ENST00000371706	hsa-miR-561-3p	136440584	136440590	7mer-m8	136440583	136440604	155	-10.41
CAediting_442554	chr5_154685830_+	ENSG00000148396.17	ENST00000371706	hsa-miR-1303	136441370	136441376	7mer-m8	136441369	136441387	152	-20.87
CAediting_524911	chr7_5495852_-	ENSG00000148396.17	ENST00000371706	hsa-miR-589-3p	136441273	136441279	7mer-m8	136441272	136441295	140	-13.73
CAediting_1229415	chr17_67471547_+	ENSG00000148396.17	ENST00000313084	hsa-miR-548aa	136440417	136440423	7mer-m8	136440416	136440441	152	-10.4
CAediting_228905	chr2_188297554_+	ENSG00000148396.17	ENST00000313084	hsa-miR-561-3p	136440584	136440590	7mer-m8	136440583	136440604	155	-10.41
CAediting_442554	chr5_154685830_+	ENSG00000148396.17	ENST00000313084	hsa-miR-1303	136441370	136441376	7mer-m8	136441369	136441387	152	-20.87
CAediting_524911	chr7_5495852_-	ENSG00000148396.17	ENST00000313084	hsa-miR-589-3p	136441273	136441279	7mer-m8	136441272	136441295	140	-13.73
CAediting_468389	chr6_31355314_-	ENSG00000148396.17	ENST00000313050	hsa-miR-6891-5p	136440630	136440636	7mer-m8	136440629	136440647	140	-15.7
CAediting_468389	chr6_31355314_-	ENSG00000148396.17	ENST00000313050	hsa-miR-6891-5p	136441610	136441617	8mer-1a	136441610	136441628	153	-24.7
CAediting_468389	chr6_31355314_-	ENSG00000148396.17	ENST00000290037	hsa-miR-6891-5p	136440630	136440636	7mer-m8	136440629	136440647	140	-15.7
CAediting_468389	chr6_31355314_-	ENSG00000148396.17	ENST00000290037	hsa-miR-6891-5p	136441610	136441617	8mer-1a	136441610	136441628	153	-24.7
CAediting_468389	chr6_31355314_-	ENSG00000148396.17	ENST00000277537	hsa-miR-6891-5p	136440630	136440636	7mer-m8	136440629	136440647	140	-15.7
CAediting_468389	chr6_31355314_-	ENSG00000148396.17	ENST00000277537	hsa-miR-6891-5p	136441610	136441617	8mer-1a	136441610	136441628	153	-24.7
CAediting_468389	chr6_31355314_-	ENSG00000148396.17	ENST00000453963	hsa-miR-6891-5p	136440630	136440636	7mer-m8	136440629	136440647	140	-15.7
CAediting_468389	chr6_31355314_-	ENSG00000148396.17	ENST00000453963	hsa-miR-6891-5p	136441610	136441617	8mer-1a	136441610	136441628	153	-24.7
CAediting_468389	chr6_31355314_-	ENSG00000148396.17	ENST00000371706	hsa-miR-6891-5p	136440630	136440636	7mer-m8	136440629	136440647	140	-15.7
CAediting_468389	chr6_31355314_-	ENSG00000148396.17	ENST00000371706	hsa-miR-6891-5p	136441610	136441617	8mer-1a	136441610	136441628	153	-24.7
CAediting_468389	chr6_31355314_-	ENSG00000148396.17	ENST00000313084	hsa-miR-6891-5p	136440630	136440636	7mer-m8	136440629	136440647	140	-15.7
CAediting_468389	chr6_31355314_-	ENSG00000148396.17	ENST00000313084	hsa-miR-6891-5p	136441610	136441617	8mer-1a	136441610	136441628	153	-24.7

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_524911	chr7_5495852_-	ENSG00000148396.17	ENST00000313050	hsa-miR-589-3p	136440590	136440597	8mer-1a	136440590	136440613	140	-13.84
CAediting_524911	chr7_5495852_-	ENSG00000148396.17	ENST00000290037	hsa-miR-589-3p	136440590	136440597	8mer-1a	136440590	136440613	140	-13.84
CAediting_524911	chr7_5495852_-	ENSG00000148396.17	ENST00000277537	hsa-miR-589-3p	136440590	136440597	8mer-1a	136440590	136440613	140	-13.84
CAediting_524911	chr7_5495852_-	ENSG00000148396.17	ENST00000453963	hsa-miR-589-3p	136440590	136440597	8mer-1a	136440590	136440613	140	-13.84
CAediting_524911	chr7_5495852_-	ENSG00000148396.17	ENST00000371706	hsa-miR-589-3p	136440590	136440597	8mer-1a	136440590	136440613	140	-13.84
CAediting_524911	chr7_5495852_-	ENSG00000148396.17	ENST00000313084	hsa-miR-589-3p	136440590	136440597	8mer-1a	136440590	136440613	140	-13.84

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for SEC16A

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for SEC16A

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
BLCA	CAediting_722560	chr9_136441145_-	5.26001266363128e-06	0.314224647703995	.	.	.	.
LGG	CAediting_722560	chr9_136441145_-	3.06319598935723e-08	0.381922158051052	.	.	.	.
BRCA	CAediting_722560	chr9_136441145_-	1.01972062642446e-25	0.374237670981344	.	.	.	.
LIHC	CAediting_722560	chr9_136441145_-	4.51228997003621e-07	0.32472128001216	.	.	.	.
CESC	CAediting_722560	chr9_136441145_-	0.00107852321487268	0.262663560861761	.	.	.	.
LUAD	CAediting_722560	chr9_136441145_-	2.15007514848137e-15	0.414655178632835	.	.	.	.
COAD	CAediting_722560	chr9_136441145_-	0.0039683192577568	0.231612358941922	.	.	.	.
LUSC	CAediting_722560	chr9_136441145_-	1.34203462147869e-12	0.412495022421727	.	.	.	.
GBM	CAediting_722560	chr9_136441145_-	0.0339985999463617	0.274200598818919	.	.	.	.
PRAD	CAediting_722560	chr9_136441145_-	2.19397295584052e-08	0.386538667114364	.	.	.	.
HNSC	CAediting_722560	chr9_136441145_-	0.000122102039917179	0.241080758855365	.	.	.	.
STAD	CAediting_722560	chr9_136441145_-	6.75727828002191e-06	0.324994567516343	.	.	.	.
KIRC	CAediting_722560	chr9_136441145_-	0.00181261659789348	0.193677025569897	.	.	.	.
UCEC	CAediting_722560	chr9_136441145_-	1.34104659322745e-05	0.257376699911985	.	.	.	.
KIRP	CAediting_722560	chr9_136441145_-	0.0223598665761567	0.282992423418824	.	.	.	.
OV	CAediting_722560	chr9_136441145_-	3.5138760032854e-09	0.361179274719683	.	.	.	.
PAAD	CAediting_722560	chr9_136441145_-	0.00117309965370748	0.328043068542725	.	.	.	.
PCPG	CAediting_722560	chr9_136441145_-	0.000500649008919588	0.335394687463425	.	.	.	.
SKCM	CAediting_722560	chr9_136441145_-	4.16195685160466e-10	0.443188441112416	.	.	.	.
READ	CAediting_722560	chr9_136441145_-	0.0395553170976688	0.281011194874206	.	.	.	.
SARC	CAediting_722560	chr9_136441145_-	1.96336475404915e-06	0.392179869592294	.	.	.	.
TGCT	CAediting_722560	chr9_136441145_-	8.2712996496025e-07	0.52156946561591	.	.	.	.
BRCA	CAediting_722562	chr9_136441171_-	1.41205440675368e-06	0.23755539805117	.	.	.	.
CESC	CAediting_722562	chr9_136441171_-	0.00386264453706676	0.34839350075838	.	.	0.0421182525421897	0.249050759642839
LUAD	CAediting_722562	chr9_136441171_-	1.0027218261513e-06	0.367889363132526	.	.	.	.
LUSC	CAediting_722562	chr9_136441171_-	3.70745670218087e-09	0.416498447878703	.	.	.	.
UCEC	CAediting_722562	chr9_136441171_-	0.0417384542346969	0.171117327383452	.	.	.	.
OV	CAediting_722562	chr9_136441171_-	0.00608023861214998	0.214686908356877	.	.	.	.
PAAD	CAediting_722562	chr9_136441171_-	0.00361448352081954	0.385921583282044	.	.	.	.
SARC	CAediting_722562	chr9_136441171_-	0.00112510177512338	0.36430874713874	.	.	.	.

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Relation with cancer stages for SEC16A

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
CESC	clinical_stage	CAediting_722560	chr9_136441145_-	0.00540743281226219	-0.22459016425937
HNSC	pathologic_stage	CAediting_722562	chr9_136441171_-	0.0304631415657466	0.208365833546477
LUAD	pathologic_stage	CAediting_722562	chr9_136441171_-	0.0222421185577186	-0.177375004102453
THCA	pathologic_stage	CAediting_722560	chr9_136441145_-	0.00522102086827187	0.185617700382287
THCA	pathologic_stage	CAediting_722562	chr9_136441171_-	0.00326365806167653	0.269799189661002

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Relation with survival for SEC16A

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
READ	CAediting_722560	chr9_136441145_-	0.0170311478350414	0.0312405	3.59801e+11

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RelatedDrugs for SEC16A

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for SEC16A

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene