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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: PIEZO1 (CAeditome ID:9780)

Gene summary for PIEZO1

check button Gene summary
Gene informationGene symbol

PIEZO1

Gene ID

9780

Gene namepiezo type mechanosensitive ion channel component 1
SynonymsDHS|FAM38A|LMPH3|LMPHM6|Mib
Cytomap

16q24.3

Type of geneprotein-coding
Descriptionpiezo-type mechanosensitive ion channel component 1family with sequence similarity 38, member Amembrane protein induced by beta-amyloid treatment
Modification date20210522
UniProtAcc

Q92508

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
PIEZO1

GO:0005783

Piezo-type mechanosensitive ion channel component 1

20016066


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RNA A-to-I events for PIEZO1

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000103335.18
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_1143421(88717854, -), CAediting_1143422(88717860, -), CAediting_1143423(88717867, -), CAediting_1143424(88717888, -), CAediting_1143425(88717889, -), CAediting_1143426(88717902, -), CAediting_1143427(88717903, -), CAediting_1143428(88717904, -), CAediting_1143429(88717948, -), CAediting_1143430(88717959, -), CAediting_1143431(88717971, -), CAediting_1143432(88717974, -), CAediting_1143433(88717983, -), CAediting_1143434(88717988, -), CAediting_1143435(88717996, -), CAediting_1143436(88718000, -), CAediting_1143437(88718001, -), CAediting_1143438(88718021, -), CAediting_1143439(88718026, -), CAediting_1143440(88718039, -), CAediting_1143441(88718050, -), CAediting_1143442(88718051, -), CAediting_1143443(88718062, -), CAediting_1143444(88718065, -), CAediting_1143445(88718259, -), CAediting_1143446(88730482, -), CAediting_1143447(88730515, -), CAediting_1143448(88730516, -), CAediting_1143449(88730659, -), CAediting_1143450(88730682, -), CAediting_1143451(88730723, -), CAediting_1143452(88764508, -), CAediting_1143453(88764509, -), CAediting_1143454(88764651, -), CAediting_1143455(88764675, -), CAediting_1143456(88765742, -), CAediting_1143457(88765802, -), CAediting_1143458(88769331, -), CAediting_1143459(88772662, -), CAediting_1143460(88772667, -), CAediting_1143461(88774309, -), CAediting_1143462(88774328, -), CAediting_1143463(88775549, -), CAediting_1143464(88775589, -), CAediting_1143465(88775605, -), CAediting_1143466(88775607, -), CAediting_1143467(88777000, -), CAediting_1143468(88777110, -), CAediting_1143469(88777111, -), CAediting_1143470(88777137, -), CAediting_1143471(88777143, -), CAediting_1143472(88777146, -), CAediting_1143473(88777151, -), CAediting_1143474(88777155, -), CAediting_1143475(88777169, -), CAediting_1143476(88777176, -), CAediting_1143477(88777191, -), CAediting_1143478(88777192, -), CAediting_1143479(88777200, -), CAediting_1143480(88777205, -), CAediting_1143481(88777238, -), CAediting_1143482(88777243, -), CAediting_1143483(88777244, -), CAediting_1143484(88777252, -), CAediting_1143485(88779114, -), CAediting_1143486(88779134, -), CAediting_1143487(88779138, -), CAediting_1143488(88779203, -), CAediting_1143489(88779207, -), CAediting_1143490(88780716, -), CAediting_1143491(88780726, -), CAediting_1143492(88780778, -), CAediting_1143493(88780781, -), CAediting_1143494(88780817, -), CAediting_1143495(88780857, -), CAediting_1143496(88780874, -), CAediting_1143497(88780875, -), CAediting_1143498(88780955, -), CAediting_1143499(88782207, -), CAediting_1143500(88782225, -), CAediting_1143501(88782226, -), CAediting_1143502(88782231, -), CAediting_1143503(88782234, -), CAediting_1143504(88782238, -), CAediting_1143505(88782248, -), CAediting_1143506(88782311, -), CAediting_1143507(88782315, -), CAediting_1143508(88782391, -),

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RNA editing positional annotations for PIEZO1 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_1143421chr16_88717854_-ncRNA_exonic
CAediting_1143422chr16_88717860_-ncRNA_exonic
CAediting_1143423chr16_88717867_-ncRNA_exonic
CAediting_1143424chr16_88717888_-ncRNA_exonic
CAediting_1143425chr16_88717889_-ncRNA_exonic
CAediting_1143426chr16_88717902_-ncRNA_exonic
CAediting_1143427chr16_88717903_-ncRNA_exonic
CAediting_1143428chr16_88717904_-ncRNA_exonic
CAediting_1143429chr16_88717948_-ncRNA_exonic
CAediting_1143430chr16_88717959_-ncRNA_exonic
CAediting_1143431chr16_88717971_-ncRNA_exonic
CAediting_1143432chr16_88717974_-ncRNA_exonic
CAediting_1143433chr16_88717983_-ncRNA_exonic
CAediting_1143434chr16_88717988_-ncRNA_exonic
CAediting_1143435chr16_88717996_-ncRNA_exonic
CAediting_1143436chr16_88718000_-ncRNA_exonic
CAediting_1143437chr16_88718001_-ncRNA_exonic
CAediting_1143438chr16_88718021_-ncRNA_exonic
CAediting_1143439chr16_88718026_-ncRNA_exonic
CAediting_1143440chr16_88718039_-ncRNA_exonic
CAediting_1143441chr16_88718050_-ncRNA_exonic
CAediting_1143442chr16_88718051_-ncRNA_exonic
CAediting_1143443chr16_88718062_-ncRNA_exonic
CAediting_1143444chr16_88718065_-ncRNA_exonic
CAediting_1143445chr16_88718259_-ncRNA_exonic
CAediting_1143446chr16_88730482_-intronic
CAediting_1143447chr16_88730515_-intronic
CAediting_1143448chr16_88730516_-intronic
CAediting_1143449chr16_88730659_-intronic
CAediting_1143450chr16_88730682_-intronic
CAediting_1143451chr16_88730723_-intronic
CAediting_1143452chr16_88764508_-intronic
CAediting_1143453chr16_88764509_-intronic
CAediting_1143454chr16_88764651_-intronic
CAediting_1143455chr16_88764675_-intronic
CAediting_1143456chr16_88765742_-intronic
CAediting_1143457chr16_88765802_-intronic
CAediting_1143458chr16_88769331_-intronic
CAediting_1143459chr16_88772662_-intronic
CAediting_1143460chr16_88772667_-intronic
CAediting_1143461chr16_88774309_-intronic
CAediting_1143462chr16_88774328_-intronic
CAediting_1143463chr16_88775549_-intronic
CAediting_1143464chr16_88775589_-intronic
CAediting_1143465chr16_88775605_-intronic
CAediting_1143466chr16_88775607_-intronic
CAediting_1143467chr16_88777000_-intronic
CAediting_1143468chr16_88777110_-intronic
CAediting_1143469chr16_88777111_-intronic
CAediting_1143470chr16_88777137_-intronic
CAediting_1143471chr16_88777143_-intronic
CAediting_1143472chr16_88777146_-intronic
CAediting_1143473chr16_88777151_-intronic
CAediting_1143474chr16_88777155_-intronic
CAediting_1143475chr16_88777169_-intronic
CAediting_1143476chr16_88777176_-intronic
CAediting_1143477chr16_88777191_-intronic
CAediting_1143478chr16_88777192_-intronic
CAediting_1143479chr16_88777200_-intronic
CAediting_1143480chr16_88777205_-intronic
CAediting_1143481chr16_88777238_-intronic
CAediting_1143482chr16_88777243_-intronic
CAediting_1143483chr16_88777244_-intronic
CAediting_1143484chr16_88777252_-intronic
CAediting_1143485chr16_88779114_-intronic
CAediting_1143486chr16_88779134_-intronic
CAediting_1143487chr16_88779138_-intronic
CAediting_1143488chr16_88779203_-intronic
CAediting_1143489chr16_88779207_-intronic
CAediting_1143490chr16_88780716_-intronic
CAediting_1143491chr16_88780726_-intronic
CAediting_1143492chr16_88780778_-intronic
CAediting_1143493chr16_88780781_-intronic
CAediting_1143494chr16_88780817_-intronic
CAediting_1143495chr16_88780857_-intronic
CAediting_1143496chr16_88780874_-intronic
CAediting_1143497chr16_88780875_-intronic
CAediting_1143498chr16_88780955_-intronic
CAediting_1143499chr16_88782207_-intronic
CAediting_1143500chr16_88782225_-intronic
CAediting_1143501chr16_88782226_-intronic
CAediting_1143502chr16_88782231_-intronic
CAediting_1143503chr16_88782234_-intronic
CAediting_1143504chr16_88782238_-intronic
CAediting_1143505chr16_88782248_-intronic
CAediting_1143506chr16_88782311_-intronic
CAediting_1143507chr16_88782315_-intronic
CAediting_1143508chr16_88782391_-intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_1143421chr16_88717854_-SINEAluAluSx3
CAediting_1143422chr16_88717860_-SINEAluAluSx3
CAediting_1143423chr16_88717867_-SINEAluAluSx3
CAediting_1143424chr16_88717888_-SINEAluAluSx3
CAediting_1143425chr16_88717889_-SINEAluAluSx3
CAediting_1143426chr16_88717902_-SINEAluAluSx3
CAediting_1143427chr16_88717903_-SINEAluAluSx3
CAediting_1143428chr16_88717904_-SINEAluAluSx3
CAediting_1143429chr16_88717948_-SINEAluAluSx3
CAediting_1143430chr16_88717959_-SINEAluAluSx3
CAediting_1143431chr16_88717971_-SINEAluAluSx3
CAediting_1143432chr16_88717974_-SINEAluAluSx3
CAediting_1143433chr16_88717983_-SINEAluAluSx3
CAediting_1143434chr16_88717988_-SINEAluAluSx3
CAediting_1143435chr16_88717996_-SINEAluAluSx3
CAediting_1143436chr16_88718000_-SINEAluAluSx3
CAediting_1143437chr16_88718001_-SINEAluAluSx3
CAediting_1143438chr16_88718021_-SINEAluAluSx3
CAediting_1143439chr16_88718026_-SINEAluAluSx3
CAediting_1143440chr16_88718039_-SINEAluAluSx3
CAediting_1143441chr16_88718050_-SINEAluAluSx3
CAediting_1143442chr16_88718051_-SINEAluAluSx3
CAediting_1143443chr16_88718062_-SINEAluAluSx3
CAediting_1143444chr16_88718065_-SINEAluAluSx3
CAediting_1143445chr16_88718259_-LINEL1L1MB7
CAediting_1143446chr16_88730482_-SINEAluAluSx
CAediting_1143447chr16_88730515_-SINEAluAluSx
CAediting_1143448chr16_88730516_-SINEAluAluSx
CAediting_1143449chr16_88730659_-SINEAluAluJr
CAediting_1143450chr16_88730682_-SINEAluAluJr
CAediting_1143451chr16_88730723_-SINEAluAluJr
CAediting_1143452chr16_88764508_-SINEAluAluSg
CAediting_1143453chr16_88764509_-SINEAluAluSg
CAediting_1143454chr16_88764651_-SINEAluAluSg
CAediting_1143455chr16_88764675_-SINEAluAluSg
CAediting_1143456chr16_88765742_-SINEAluAluSx1
CAediting_1143457chr16_88765802_-SINEAluAluSx1
CAediting_1143458chr16_88769331_-SINEAluAluJr
CAediting_1143459chr16_88772662_-SINEAluAluSc
CAediting_1143460chr16_88772667_-SINEAluAluSc
CAediting_1143461chr16_88774309_-SINEAluAluSz6
CAediting_1143462chr16_88774328_-SINEAluAluSz6
CAediting_1143463chr16_88775549_-SINEAluAluSx1
CAediting_1143464chr16_88775589_-SINEAluAluSx1
CAediting_1143465chr16_88775605_-SINEAluAluSx1
CAediting_1143466chr16_88775607_-SINEAluAluSx1
CAediting_1143467chr16_88777000_-SINEAluAluSq2
CAediting_1143468chr16_88777110_-SINEAluAluSq2
CAediting_1143469chr16_88777111_-SINEAluAluSq2
CAediting_1143470chr16_88777137_-SINEAluAluSq2
CAediting_1143471chr16_88777143_-SINEAluAluSq2
CAediting_1143472chr16_88777146_-SINEAluAluSq2
CAediting_1143473chr16_88777151_-SINEAluAluSq2
CAediting_1143474chr16_88777155_-SINEAluAluSq2
CAediting_1143475chr16_88777169_-SINEAluAluSq2
CAediting_1143476chr16_88777176_-SINEAluAluSq2
CAediting_1143477chr16_88777191_-SINEAluAluSq2
CAediting_1143478chr16_88777192_-SINEAluAluSq2
CAediting_1143479chr16_88777200_-SINEAluAluSq2
CAediting_1143480chr16_88777205_-SINEAluAluSq2
CAediting_1143481chr16_88777238_-SINEAluAluSq2
CAediting_1143482chr16_88777243_-SINEAluAluSq2
CAediting_1143483chr16_88777244_-SINEAluAluSq2
CAediting_1143484chr16_88777252_-SINEAluAluSq2
CAediting_1143485chr16_88779114_-SINEAluAluSx1
CAediting_1143486chr16_88779134_-SINEAluAluSx1
CAediting_1143487chr16_88779138_-SINEAluAluSx1
CAediting_1143488chr16_88779203_-SINEAluAluSx1
CAediting_1143489chr16_88779207_-SINEAluAluSx1
CAediting_1143490chr16_88780716_-SINEAluAluSz
CAediting_1143491chr16_88780726_-SINEAluAluSz
CAediting_1143492chr16_88780778_-SINEAluAluSz
CAediting_1143493chr16_88780781_-SINEAluAluSz
CAediting_1143494chr16_88780817_-SINEAluAluSz
CAediting_1143495chr16_88780857_-SINEAluAluSz
CAediting_1143496chr16_88780874_-SINEAluAluSz
CAediting_1143497chr16_88780875_-SINEAluAluSz
CAediting_1143498chr16_88780955_-SINEAluAluSz
CAediting_1143499chr16_88782207_-SINEAluAluJr
CAediting_1143500chr16_88782225_-SINEAluAluJr
CAediting_1143501chr16_88782226_-SINEAluAluJr
CAediting_1143502chr16_88782231_-SINEAluAluJr
CAediting_1143503chr16_88782234_-SINEAluAluJr
CAediting_1143504chr16_88782238_-SINEAluAluJr
CAediting_1143505chr16_88782248_-SINEAluAluJr
CAediting_1143506chr16_88782311_-SINEAluAluJr
CAediting_1143507chr16_88782315_-SINEAluAluJr
CAediting_1143508chr16_88782391_-SINEAluAluJr

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RNA A-to-I editing events in the alternative splicing sites for PIEZO1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
IRCAediting_1143438chr16_88718021_-88718003:887180253SS0+16iCTGTAGCCTCTGCCTCCCAGGTT5.5CTGTGGCCTCTGCCTCCCAGGTT8.5

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000103335.18.PIEZO1.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000103335.18.PIEZO1.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PIEZO1

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for PIEZO1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for PIEZO1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_980496chr14_31014685_-ENSG00000103335.18ENST00000419505hsa-miR-624-3p88716215887162217mer-m88871621488716232146-19.42
CAediting_846604chr11_93733708_-ENSG00000103335.18ENST00000419505hsa-miR-1304-3p88715787887157948mer-1a8871578788715811154-21.23
CAediting_688080chr9_63819626_+ENSG00000103335.18ENST00000419505hsa-miR-4477b88715735887157417mer-m88871573488715755140-12.8
CAediting_77128chr1_85133844_+ENSG00000103335.18ENST00000419505hsa-miR-4423-3p88716625887166317mer-m88871662488716644140-11.89
CAediting_396018chr5_1062918_-ENSG00000103335.18ENST00000419505hsa-miR-463588715734887157407mer-m88871573388715755145-20.89
CAediting_573000chr7_92204081_-ENSG00000103335.18ENST00000419505hsa-miR-1285-5p88715786887157927mer-m88871578588715805145-17.96
CAediting_1524209chrX_134546392_-ENSG00000103335.18ENST00000419505hsa-miR-503-5p88715993887159986mer8871599288716015140-24.74
CAediting_1524209chrX_134546392_-ENSG00000103335.18ENST00000419505hsa-miR-503-5p88715409887154157mer-m88871540888715432146-24.2

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for PIEZO1

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for PIEZO1

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
BLCACAediting_1143431chr16_88717971_-3.06841128110276e-060.356167210815384....
LGGCAediting_1143431chr16_88717971_-0.008958341843184030.24483871529288....
BRCACAediting_1143431chr16_88717971_-1.16542888937507e-110.325308064775175....
CESCCAediting_1143431chr16_88717971_-1.07956160563334e-050.348553858397797....
LUADCAediting_1143431chr16_88717971_-0.0002171938284830480.280004491586796....
COADCAediting_1143431chr16_88717971_-0.006752370875034630.232959914328107....
LUSCCAediting_1143431chr16_88717971_-0.007683773341010650.212012830469941....
PRADCAediting_1143431chr16_88717971_-1.20501960121342e-050.282387286092033....
STADCAediting_1143431chr16_88717971_-0.01676379270311380.153319381000752....
ESCACAediting_1143431chr16_88717971_-0.02374412302083060.179287370633857....
SARCCAediting_1143431chr16_88717971_-0.0008420188680050180.426520541935995....
BLCACAediting_1143436chr16_88718000_-0.00150344866642860.265794165877242....
LGGCAediting_1143436chr16_88718000_-....0.0005509496385611520.245803576872349
BRCACAediting_1143436chr16_88718000_-8.76594403534672e-050.175727033705624....
CESCCAediting_1143436chr16_88718000_-0.01472064247613230.224067105866014....
LUADCAediting_1143436chr16_88718000_-4.83024772767066e-050.286006478863214....
LUSCCAediting_1143436chr16_88718000_-0.04220999289532520.16392491447814....
PRADCAediting_1143436chr16_88718000_-0.0003441047356192940.245862335310229....
HNSCCAediting_1143436chr16_88718000_-0.01482070089104460.244280732455827....
ESCACAediting_1143436chr16_88718000_-..1.93462568351996e-060.40790623207873..
PAADCAediting_1143436chr16_88718000_-..0.04072921495547670.23849073130522..
SKCMCAediting_1143436chr16_88718000_-0.00952529157416020.210364708112054....
BRCACAediting_1143437chr16_88718001_-0.007708956475809360.177216044383179....
LUADCAediting_1143440chr16_88718039_-0.03299955729450190.164599469692193....
COADCAediting_1143440chr16_88718039_-..0.02315491549383120.265576593379973..

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Relation with cancer stages for PIEZO1

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
COADpathologic_stageCAediting_1143431chr16_88717971_-0.0408034522664881-0.181079126756162
ESCAclinical_stageCAediting_1143436chr16_88718000_-0.000352303637109248-0.531202142341282
HNSCclinical_stageCAediting_1143440chr16_88718039_-0.01902174371149640.244120367902179
KIRCpathologic_stageCAediting_1143440chr16_88718039_-0.02054303531771380.167513642017064
LIHCpathologic_stageCAediting_1143440chr16_88718039_-0.0499804256149326-0.268107784574636
LUSCpathologic_stageCAediting_1143431chr16_88717971_-0.0151572199763040.193533828769904
LUSCpathologic_stageCAediting_1143440chr16_88718039_-0.03083602826392320.170249652139042
OVclinical_stageCAediting_1143431chr16_88717971_-0.01327467859148130.19361100508227

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Relation with survival for PIEZO1

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR
BRCACAediting_1143431chr16_88717971_-0.02308168986615670.01350586.05504
COADCAediting_1143431chr16_88717971_-0.02953595447428760.04257310.0670276

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RelatedDrugs for PIEZO1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for PIEZO1

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
PIEZO1C4551512DEHYDRATED HEREDITARY STOMATOCYTOSIS 1 WITH OR WITHOUT PSEUDOHYPERKALEMIA AND/OR PERINATAL EDEMA7GENOMICS_ENGLAND;UNIPROT
PIEZO1C4225184LYMPHATIC MALFORMATION 64CTD_human;GENOMICS_ENGLAND;UNIPROT
PIEZO1C0272051Xerocytosis3GENOMICS_ENGLAND;ORPHANET
PIEZO1C0272048stomatocytic anemia2GENOMICS_ENGLAND
PIEZO1C0677598Stomatocytosis Result2GENOMICS_ENGLAND