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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: IFT140 (CAeditome ID:9742)

Gene summary for IFT140

check button Gene summary
Gene informationGene symbol

IFT140

Gene ID

9742

Gene nameintraflagellar transport 140
SynonymsMZSDS|RP80|SRTD9|WDTC2|c305C8.4|c380F5.1|gs114
Cytomap

16p13.3

Type of geneprotein-coding
Descriptionintraflagellar transport protein 140 homologWD and tetratricopeptide repeats protein 2intraflagellar transport 140 homolog
Modification date20210518
UniProtAcc

Q96RY7

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
IFT140

GO:0005813

Intraflagellar transport protein 140 homolog

23418020

IFT140

GO:0005929

Intraflagellar transport protein 140 homolog

27932497

IFT140

GO:0036064

Intraflagellar transport protein 140 homolog

22503633

IFT140

GO:0030991

Intraflagellar transport protein 140 homolog

20889716

IFT140

GO:0030991

Intraflagellar transport protein 140 homolog

27932497


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RNA A-to-I events for IFT140

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000187535.12

check button RNA A-to-I editing events in Cancer.
CAediting_1078636(1512743, -), CAediting_1078637(1512783, -), CAediting_1078638(1515436, -), CAediting_1078639(1515437, -), CAediting_1078640(1515440, -), CAediting_1078641(1515441, -), CAediting_1078642(1515467, -), CAediting_1078643(1515483, -), CAediting_1078644(1515499, -), CAediting_1078645(1515504, -), CAediting_1078646(1515545, -), CAediting_1078647(1515563, -), CAediting_1078648(1515571, -), CAediting_1078649(1515574, -), CAediting_1078650(1515615, -), CAediting_1078651(1515616, -), CAediting_1078652(1515670, -), CAediting_1078653(1515686, -), CAediting_1078654(1515692, -), CAediting_1078655(1516134, -), CAediting_1078656(1516605, -), CAediting_1078657(1517126, -), CAediting_1078658(1517804, -), CAediting_1078659(1517890, -), CAediting_1078660(1517914, -), CAediting_1078661(1517930, -), CAediting_1078662(1517935, -), CAediting_1078663(1517982, -), CAediting_1078664(1518002, -), CAediting_1078665(1518014, -), CAediting_1078666(1518026, -), CAediting_1078667(1518054, -), CAediting_1078668(1518056, -), CAediting_1078669(1518057, -), CAediting_1078670(1518084, -), CAediting_1078671(1518110, -), CAediting_1078672(1518111, -), CAediting_1078673(1522730, -), CAediting_1078674(1555984, -), CAediting_1078675(1555994, -), CAediting_1078676(1556993, -), CAediting_1078677(1577332, -), CAediting_1078678(1577341, -), CAediting_1078679(1577342, -), CAediting_1078680(1577343, -), CAediting_1078681(1577346, -), CAediting_1078682(1577357, -), CAediting_1078683(1577358, -), CAediting_1078684(1577361, -), CAediting_1078685(1577362, -), CAediting_1078686(1577363, -), CAediting_1078687(1577379, -), CAediting_1078688(1577386, -), CAediting_1078689(1577406, -), CAediting_1078690(1577408, -), CAediting_1078691(1577410, -), CAediting_1078692(1577411, -), CAediting_1078693(1577427, -), CAediting_1078694(1577428, -), CAediting_1078695(1577430, -), CAediting_1078696(1577434, -), CAediting_1078697(1577450, -), CAediting_1078698(1577490, -), CAediting_1078699(1577637, -), CAediting_1078700(1577657, -), CAediting_1078701(1577743, -), CAediting_1078702(1577755, -), CAediting_1078703(1578637, -), CAediting_1078704(1578638, -), CAediting_1078705(1578652, -), CAediting_1078706(1578784, -), CAediting_1078707(1578785, -), CAediting_1078708(1578850, -), CAediting_1078709(1578925, -), CAediting_1078710(1578928, -), CAediting_1078711(1578992, -), CAediting_1078712(1578998, -), CAediting_1078713(1578999, -), CAediting_1078714(1579061, -), CAediting_1078715(1579076, -), CAediting_1078716(1579077, -), CAediting_1078717(1579083, -), CAediting_1078718(1579096, -), CAediting_1078719(1579117, -), CAediting_1078720(1579124, -), CAediting_1078721(1579129, -), CAediting_1078722(1579138, -), CAediting_1078723(1579171, -), CAediting_1078724(1579173, -), CAediting_1078725(1579174, -), CAediting_1078726(1579176, -), CAediting_1078727(1579177, -),

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RNA editing positional annotations for IFT140 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_1078636chr16_1512743_-ncRNA_intronic
CAediting_1078637chr16_1512783_-ncRNA_intronic
CAediting_1078638chr16_1515436_-ncRNA_intronic
CAediting_1078639chr16_1515437_-ncRNA_intronic
CAediting_1078640chr16_1515440_-ncRNA_intronic
CAediting_1078641chr16_1515441_-ncRNA_intronic
CAediting_1078642chr16_1515467_-ncRNA_intronic
CAediting_1078643chr16_1515483_-ncRNA_intronic
CAediting_1078644chr16_1515499_-ncRNA_intronic
CAediting_1078645chr16_1515504_-ncRNA_intronic
CAediting_1078646chr16_1515545_-ncRNA_intronic
CAediting_1078647chr16_1515563_-ncRNA_intronic
CAediting_1078648chr16_1515571_-ncRNA_intronic
CAediting_1078649chr16_1515574_-ncRNA_intronic
CAediting_1078650chr16_1515615_-ncRNA_intronic
CAediting_1078651chr16_1515616_-ncRNA_intronic
CAediting_1078652chr16_1515670_-ncRNA_intronic
CAediting_1078653chr16_1515686_-ncRNA_intronic
CAediting_1078654chr16_1515692_-ncRNA_intronic
CAediting_1078655chr16_1516134_-ncRNA_intronic
CAediting_1078656chr16_1516605_-ncRNA_intronic
CAediting_1078657chr16_1517126_-ncRNA_intronic
CAediting_1078658chr16_1517804_-ncRNA_intronic
CAediting_1078659chr16_1517890_-ncRNA_intronic
CAediting_1078660chr16_1517914_-ncRNA_intronic
CAediting_1078661chr16_1517930_-ncRNA_intronic
CAediting_1078662chr16_1517935_-ncRNA_intronic
CAediting_1078663chr16_1517982_-ncRNA_intronic
CAediting_1078664chr16_1518002_-ncRNA_intronic
CAediting_1078665chr16_1518014_-ncRNA_intronic
CAediting_1078666chr16_1518026_-ncRNA_intronic
CAediting_1078667chr16_1518054_-ncRNA_intronic
CAediting_1078668chr16_1518056_-ncRNA_intronic
CAediting_1078669chr16_1518057_-ncRNA_intronic
CAediting_1078670chr16_1518084_-ncRNA_intronic
CAediting_1078671chr16_1518110_-ncRNA_intronic
CAediting_1078672chr16_1518111_-ncRNA_intronic
CAediting_1078673chr16_1522730_-ncRNA_intronic
CAediting_1078674chr16_1555984_-ncRNA_intronic
CAediting_1078675chr16_1555994_-ncRNA_intronic
CAediting_1078676chr16_1556993_-ncRNA_intronic
CAediting_1078677chr16_1577332_-ncRNA_exonic
CAediting_1078678chr16_1577341_-ncRNA_exonic
CAediting_1078679chr16_1577342_-ncRNA_exonic
CAediting_1078680chr16_1577343_-ncRNA_exonic
CAediting_1078681chr16_1577346_-ncRNA_exonic
CAediting_1078682chr16_1577357_-ncRNA_exonic
CAediting_1078683chr16_1577358_-ncRNA_exonic
CAediting_1078684chr16_1577361_-ncRNA_exonic
CAediting_1078685chr16_1577362_-ncRNA_exonic
CAediting_1078686chr16_1577363_-ncRNA_exonic
CAediting_1078687chr16_1577379_-ncRNA_exonic
CAediting_1078688chr16_1577386_-ncRNA_exonic
CAediting_1078689chr16_1577406_-ncRNA_exonic
CAediting_1078690chr16_1577408_-ncRNA_exonic
CAediting_1078691chr16_1577410_-ncRNA_exonic
CAediting_1078692chr16_1577411_-ncRNA_exonic
CAediting_1078693chr16_1577427_-ncRNA_exonic
CAediting_1078694chr16_1577428_-ncRNA_exonic
CAediting_1078695chr16_1577430_-ncRNA_exonic
CAediting_1078696chr16_1577434_-ncRNA_exonic
CAediting_1078697chr16_1577450_-ncRNA_exonic
CAediting_1078698chr16_1577490_-ncRNA_exonic
CAediting_1078699chr16_1577637_-ncRNA_exonic
CAediting_1078700chr16_1577657_-ncRNA_exonic
CAediting_1078701chr16_1577743_-ncRNA_exonic
CAediting_1078702chr16_1577755_-ncRNA_exonic
CAediting_1078703chr16_1578637_-ncRNA_intronic
CAediting_1078704chr16_1578638_-ncRNA_intronic
CAediting_1078705chr16_1578652_-ncRNA_intronic
CAediting_1078706chr16_1578784_-ncRNA_intronic
CAediting_1078707chr16_1578785_-ncRNA_intronic
CAediting_1078708chr16_1578850_-ncRNA_intronic
CAediting_1078709chr16_1578925_-ncRNA_intronic
CAediting_1078710chr16_1578928_-ncRNA_intronic
CAediting_1078711chr16_1578992_-ncRNA_intronic
CAediting_1078712chr16_1578998_-ncRNA_intronic
CAediting_1078713chr16_1578999_-ncRNA_intronic
CAediting_1078714chr16_1579061_-ncRNA_intronic
CAediting_1078715chr16_1579076_-ncRNA_intronic
CAediting_1078716chr16_1579077_-ncRNA_intronic
CAediting_1078717chr16_1579083_-ncRNA_intronic
CAediting_1078718chr16_1579096_-ncRNA_intronic
CAediting_1078719chr16_1579117_-ncRNA_intronic
CAediting_1078720chr16_1579124_-ncRNA_intronic
CAediting_1078721chr16_1579129_-ncRNA_intronic
CAediting_1078722chr16_1579138_-ncRNA_intronic
CAediting_1078723chr16_1579171_-ncRNA_intronic
CAediting_1078724chr16_1579173_-ncRNA_intronic
CAediting_1078725chr16_1579174_-ncRNA_intronic
CAediting_1078726chr16_1579176_-ncRNA_intronic
CAediting_1078727chr16_1579177_-ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_1078636chr16_1512743_-SINEAluAluJb
CAediting_1078637chr16_1512783_-SINEAluAluJb
CAediting_1078638chr16_1515436_-SINEAluAluJr
CAediting_1078639chr16_1515437_-SINEAluAluJr
CAediting_1078640chr16_1515440_-SINEAluAluJr
CAediting_1078641chr16_1515441_-SINEAluAluJr
CAediting_1078642chr16_1515467_-SINEAluAluJr
CAediting_1078643chr16_1515483_-SINEAluAluJr
CAediting_1078644chr16_1515499_-SINEAluAluJr
CAediting_1078645chr16_1515504_-SINEAluAluJr
CAediting_1078646chr16_1515545_-SINEAluAluJr
CAediting_1078647chr16_1515563_-SINEAluAluJr
CAediting_1078648chr16_1515571_-SINEAluAluJr
CAediting_1078649chr16_1515574_-SINEAluAluJr
CAediting_1078650chr16_1515615_-SINEAluAluJr
CAediting_1078651chr16_1515616_-SINEAluAluJr
CAediting_1078652chr16_1515670_-SINEAluAluJr
CAediting_1078653chr16_1515686_-SINEAluAluJr
CAediting_1078654chr16_1515692_-SINEAluAluJr
CAediting_1078655chr16_1516134_-SINEAluAluSp
CAediting_1078656chr16_1516605_-SINEAluAluY
CAediting_1078657chr16_1517126_-SINEAluAluSz
CAediting_1078659chr16_1517890_-SINEAluAluJb
CAediting_1078660chr16_1517914_-SINEAluAluJb
CAediting_1078661chr16_1517930_-SINEAluAluJb
CAediting_1078662chr16_1517935_-SINEAluAluJb
CAediting_1078663chr16_1517982_-SINEAluAluJb
CAediting_1078664chr16_1518002_-SINEAluAluJb
CAediting_1078665chr16_1518014_-SINEAluAluJb
CAediting_1078666chr16_1518026_-SINEAluAluJb
CAediting_1078667chr16_1518054_-SINEAluAluJb
CAediting_1078668chr16_1518056_-SINEAluAluJb
CAediting_1078669chr16_1518057_-SINEAluAluJb
CAediting_1078670chr16_1518084_-SINEAluAluJb
CAediting_1078671chr16_1518110_-SINEAluAluJb
CAediting_1078672chr16_1518111_-SINEAluAluJb
CAediting_1078673chr16_1522730_-SINEAluAluSc
CAediting_1078674chr16_1555984_-SINEAluAluSx3
CAediting_1078675chr16_1555994_-SINEAluAluSx3
CAediting_1078676chr16_1556993_-SINEAluAluSx
CAediting_1078677chr16_1577332_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078678chr16_1577341_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078679chr16_1577342_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078680chr16_1577343_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078681chr16_1577346_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078682chr16_1577357_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078683chr16_1577358_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078684chr16_1577361_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078685chr16_1577362_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078686chr16_1577363_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078687chr16_1577379_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078688chr16_1577386_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078689chr16_1577406_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078690chr16_1577408_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078691chr16_1577410_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078692chr16_1577411_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078693chr16_1577427_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078694chr16_1577428_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078695chr16_1577430_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078696chr16_1577434_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078697chr16_1577450_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078698chr16_1577490_-DNATcMar-TiggerTigger2b_Pri
CAediting_1078699chr16_1577637_-SINEAluAluSq
CAediting_1078700chr16_1577657_-SINEAluAluSq
CAediting_1078701chr16_1577743_-SINEAluAluSq
CAediting_1078702chr16_1577755_-SINEAluAluSq
CAediting_1078703chr16_1578637_-SINEAluAluSg7
CAediting_1078704chr16_1578638_-SINEAluAluSg7
CAediting_1078705chr16_1578652_-SINEAluAluSg7
CAediting_1078706chr16_1578784_-SINEAluAluJb
CAediting_1078707chr16_1578785_-SINEAluAluJb
CAediting_1078708chr16_1578850_-SINEAluAluJb
CAediting_1078709chr16_1578925_-SINEAluAluJb
CAediting_1078710chr16_1578928_-SINEAluAluJb
CAediting_1078711chr16_1578992_-SINEAluAluJb
CAediting_1078712chr16_1578998_-SINEAluAluJb
CAediting_1078713chr16_1578999_-SINEAluAluJb
CAediting_1078714chr16_1579061_-DNATcMar-TiggerTigger2a
CAediting_1078715chr16_1579076_-DNATcMar-TiggerTigger2a
CAediting_1078716chr16_1579077_-DNATcMar-TiggerTigger2a
CAediting_1078717chr16_1579083_-DNATcMar-TiggerTigger2a
CAediting_1078718chr16_1579096_-DNATcMar-TiggerTigger2a
CAediting_1078719chr16_1579117_-DNATcMar-TiggerTigger2a
CAediting_1078720chr16_1579124_-DNATcMar-TiggerTigger2a
CAediting_1078721chr16_1579129_-DNATcMar-TiggerTigger2a
CAediting_1078722chr16_1579138_-DNATcMar-TiggerTigger2a
CAediting_1078723chr16_1579171_-DNATcMar-TiggerTigger2a
CAediting_1078724chr16_1579173_-DNATcMar-TiggerTigger2a
CAediting_1078725chr16_1579174_-DNATcMar-TiggerTigger2a
CAediting_1078726chr16_1579176_-DNATcMar-TiggerTigger2a
CAediting_1078727chr16_1579177_-DNATcMar-TiggerTigger2a

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RNA A-to-I editing events in the alternative splicing sites for IFT140

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000187535.12.IFT140.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000187535.12.IFT140.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for IFT140

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
BRCA.CAediting_1078724.ENSG00000187535.IFT140.png
Soverview

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Protein coding region RNA A-to-I editings for IFT140

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for IFT140

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1078671chr16_1518110_-ENSG00000187535.12ENST00000568837hsa-miR-3199151810515181117mer-1a15181051518124141.00-22.83
CAediting_1078671chr16_1518110_-ENSG00000187535.12ENST00000568837hsa-miR-3199151810515181117mer-1a15181051518124141.00-22.83
CAediting_1078672chr16_1518111_-ENSG00000187535.12ENST00000568837hsa-miR-513a-5p151811015181167mer-m815181091518126148.00-18.03
CAediting_1078672chr16_1518111_-ENSG00000187535.12ENST00000568837hsa-miR-513a-5p151811015181167mer-m815181091518126148.00-18.03
CAediting_1078672chr16_1518111_-ENSG00000187535.12ENST00000568837hsa-miR-638151810515181117mer-1a15181051518129155.00-34.50

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1078671chr16_1518110_-ENSG00000187535.12ENST00000568837hsa-miR-10399-5p151810915181157mer-m815181081518129143-9.71
CAediting_1078672chr16_1518111_-ENSG00000187535.12ENST00000568837hsa-miR-10399-5p151810915181157mer-m815181081518129143-9.71
CAediting_1078671chr16_1518110_-ENSG00000187535.12ENST00000568837hsa-miR-6504-3p151810915181157mer-m815181081518129146-11.32
CAediting_1078672chr16_1518111_-ENSG00000187535.12ENST00000568837hsa-miR-6504-3p151810915181157mer-m815181081518129146-11.32

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_393chr1_1167164_+ENSG00000187535.12ENST00000361339hsa-miR-200b-3p151086115108677mer-m815108601510881147-10.4
CAediting_393chr1_1167164_+ENSG00000187535.12ENST00000426508hsa-miR-200b-3p151086115108677mer-m815108601510881147-10.4
CAediting_1306324chr19_13836464_-ENSG00000187535.12ENST00000397417hsa-miR-27a-3p155802815580347mer-m815580271558047151-23.05
CAediting_393chr1_1167164_+ENSG00000187535.12ENST00000397417hsa-miR-200b-3p151086115108677mer-m815108601510881147-10.4
CAediting_524911chr7_5495852_-ENSG00000187535.12ENST00000361339hsa-miR-589-3p151075715107637mer-m815107561510783160-21.78
CAediting_524911chr7_5495852_-ENSG00000187535.12ENST00000426508hsa-miR-589-3p151075715107637mer-m815107561510783160-21.78
CAediting_77128chr1_85133844_+ENSG00000187535.12ENST00000397417hsa-miR-4423-3p152528915252957mer-m815252881525308156-19.59
CAediting_573000chr7_92204081_-ENSG00000187535.12ENST00000397417hsa-miR-1285-5p152486915248757mer-m815248681524889158-26.69
CAediting_1368054chr19_46709310_-ENSG00000187535.12ENST00000397417hsa-miR-320e152393215239398mer-1a15239321523951145-19.69
CAediting_1229415chr17_67471547_+ENSG00000187535.12ENST00000397417hsa-miR-548aa152014915201557mer-m815201481520172140-13.77
CAediting_77128chr1_85133844_+ENSG00000187535.12ENST00000397417hsa-miR-4423-3p152013215201387mer-m815201311520158144-16.89
CAediting_524911chr7_5495852_-ENSG00000187535.12ENST00000397417hsa-miR-589-3p151075715107637mer-m815107561510783160-21.78

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1054808chr15_66496985_-ENSG00000187535.12ENST00000397417hsa-miR-4512152589315258986mer15258921525914147-22.49
CAediting_1524209chrX_134546392_-ENSG00000187535.12ENST00000397417hsa-miR-503-5p152358315235897mer-m815235821523603155-29.36

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for IFT140

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for IFT140

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for IFT140

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for IFT140

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for IFT140

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for IFT140

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
IFT140C1849437Mainzer-Saldino Disease5GENOMICS_ENGLAND;ORPHANET;UNIPROT
IFT140C0265275Jeune thoracic dystrophy3GENOMICS_ENGLAND;ORPHANET
IFT140C4540439RETINITIS PIGMENTOSA 803UNIPROT
IFT140C0035334Retinitis Pigmentosa1ORPHANET
IFT140C0339527Leber Congenital Amaurosis1ORPHANET