Home

Download

Statistics

Examples

Help

Contact

Editing gene: GDF15 (CAeditome ID:9518)

Gene summary for GDF15

Gene summary

Gene information	Gene symbol	GDF15
	Gene ID	9518
	Gene name	growth differentiation factor 15
	Synonyms	GDF-15\|MIC-1\|MIC1\|NAG-1\|PDF\|PLAB\|PTGFB
	Cytomap	19p13.11
	Type of gene	protein-coding
	Description	growth/differentiation factor 15NRG-1NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1NSAID-activated gene 1 proteinNSAID-regulated gene 1 proteinPTGF-betamacrophage inhibitory cytokine 1non-steroidal anti-inflammatory drug-activated
	Modification date	20210531
	UniProtAcc	Q99988
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
GDF15	GO:0042803	Growth/differentiation factor 15	29046435
GDF15	GO:0000187	Growth/differentiation factor 15	28953886
GDF15	GO:0002023	Growth/differentiation factor 15	28846097
GDF15	GO:0002023	Growth/differentiation factor 15	28846098
GDF15	GO:0002023	Growth/differentiation factor 15	28846099
GDF15	GO:0002023	Growth/differentiation factor 15	28953886
GDF15	GO:0002023	Growth/differentiation factor 15	29046435
GDF15	GO:0035860	Growth/differentiation factor 15	28953886
GDF15	GO:0051897	Growth/differentiation factor 15	28846097
GDF15	GO:0060395	Growth/differentiation factor 15	25893289
GDF15	GO:0005576	Growth/differentiation factor 15	28572090
GDF15	GO:0005576	Growth/differentiation factor 15	29046435
GDF15	GO:0005615	Growth/differentiation factor 15	25893289
GDF15	GO:0005634	Growth/differentiation factor 15	25893289
GDF15	GO:0005737	Growth/differentiation factor 15	25893289
GDF15	GO:0005794	Growth/differentiation factor 15	0000052

Top

RNA A-to-I events for GDF15

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000130513.6

RNA A-to-I editing events in Cancer.

CAediting_1319428(18375310, +), CAediting_1319429(18375396, +), CAediting_1319430(18382528, +), CAediting_1319431(18382550, +), CAediting_1319432(18382551, +), CAediting_1319433(18382596, +), CAediting_1319434(18382605, +), CAediting_1319435(18382668, +), CAediting_1319436(18382700, +), CAediting_1319437(18382703, +), CAediting_1319438(18382723, +), CAediting_1319439(18382731, +), CAediting_1319440(18382795, +), CAediting_1319441(18383467, +), CAediting_1319442(18383468, +), CAediting_1319443(18383513, +), CAediting_1319444(18383521, +), CAediting_1319445(18383547, +), CAediting_1319446(18383561, +), CAediting_1319447(18383576, +), CAediting_1319448(18383580, +), CAediting_1319449(18383612, +), CAediting_1319450(18383643, +), CAediting_1319451(18383772, +), CAediting_1319452(18383785, +), CAediting_1319453(18383791, +), CAediting_1319454(18383816, +), CAediting_1319455(18383817, +), CAediting_1319456(18383840, +), CAediting_1319457(18383861, +), CAediting_1319458(18383864, +), CAediting_1319459(18383867, +), CAediting_1319460(18383879, +), CAediting_1319461(18383883, +), CAediting_1319462(18383915, +), CAediting_1319463(18383919, +), CAediting_1319464(18383989, +), CAediting_1319465(18384168, +), CAediting_1319466(18384177, +), CAediting_1319467(18384239, +), CAediting_1319468(18384244, +), CAediting_1319469(18384254, +), CAediting_1319470(18384287, +), CAediting_1319471(18384291, +), CAediting_1319472(18384311, +), CAediting_1319473(18384313, +), CAediting_1319474(18384319, +), CAediting_1319475(18384323, +), CAediting_1319476(18384327, +), CAediting_1319477(18384340, +), CAediting_1319478(18384346, +), CAediting_1319479(18384348, +), CAediting_1319480(18384388, +), CAediting_1319481(18384431, +), CAediting_1319482(18384432, +), CAediting_1319483(18384436, +), CAediting_1319484(18384449, +), CAediting_1319485(18384461, +), CAediting_1319486(18384471, +), CAediting_1319487(18384473, +), CAediting_1319488(18384514, +), CAediting_1319489(18384523, +), CAediting_1319490(18384534, +), CAediting_1319491(18384543, +), CAediting_1319492(18384556, +), CAediting_1319493(18384568, +), CAediting_1319494(18384596, +), CAediting_1319495(18385021, +), CAediting_1319496(18385026, +), CAediting_1319497(18385036, +), CAediting_1319498(18385070, +), CAediting_1319499(18385071, +), CAediting_1319500(18385088, +), CAediting_1319501(18385133, +), CAediting_1319502(18385138, +), CAediting_1319503(18385142, +), CAediting_1319504(18385143, +), CAediting_1319505(18385156, +), CAediting_1319506(18385159, +), CAediting_1319507(18385165, +), CAediting_1319508(18385190, +), CAediting_1319509(18385195, +), CAediting_1319510(18385198, +), CAediting_1319511(18385210, +), CAediting_1319512(18385212, +), CAediting_1319513(18385215, +), CAediting_1319514(18385219, +), CAediting_1319515(18385236, +), CAediting_1319516(18385237, +), CAediting_1319517(18385238, +), CAediting_1319518(18385250, +), CAediting_1319519(18385344, +), CAediting_1319520(18385352, +), CAediting_1319521(18385356, +), CAediting_1319522(18385371, +), CAediting_1319523(18385383, +), CAediting_1319524(18385391, +), CAediting_1319525(18387046, +), CAediting_1319526(18387267, +), CAediting_1319527(18387273, +), CAediting_1319528(18387274, +), CAediting_1319529(18387287, +), CAediting_1319530(18387295, +), CAediting_1319531(18387296, +), CAediting_1319532(18387303, +), CAediting_1319533(18387314, +), CAediting_1319534(18387338, +), CAediting_1319535(18387343, +), CAediting_1319536(18387347, +), CAediting_1319537(18387363, +), CAediting_1319538(18387364, +), CAediting_1319539(18387379, +), CAediting_1319540(18387380, +), CAediting_1319541(18387383, +), CAediting_1319542(18387387, +), CAediting_1319543(18387389, +), CAediting_1319544(18387409, +), CAediting_1319545(18387423, +), CAediting_1319546(18387450, +), CAediting_1319547(18387455, +), CAediting_1319548(18387902, +), CAediting_1319549(18387921, +), CAediting_1319550(18387939, +), CAediting_1319551(18387961, +), CAediting_1319552(18387963, +), CAediting_1319553(18387970, +), CAediting_1319554(18387983, +), CAediting_1319555(18387987, +), CAediting_1319556(18388003, +), CAediting_1319557(18388006, +), CAediting_1319558(18388008, +), CAediting_1319559(18388009, +), CAediting_1319560(18388078, +), CAediting_1319561(18388095, +), CAediting_1319562(18388096, +), CAediting_1319563(18388097, +),

Top

RNA editing positional annotations for GDF15 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1319428	chr19_18375310_+	ncRNA_intronic
CAediting_1319429	chr19_18375396_+	ncRNA_intronic
CAediting_1319430	chr19_18382528_+	ncRNA_intronic
CAediting_1319431	chr19_18382550_+	ncRNA_intronic
CAediting_1319432	chr19_18382551_+	ncRNA_intronic
CAediting_1319433	chr19_18382596_+	ncRNA_intronic
CAediting_1319434	chr19_18382605_+	ncRNA_intronic
CAediting_1319435	chr19_18382668_+	ncRNA_intronic
CAediting_1319436	chr19_18382700_+	ncRNA_intronic
CAediting_1319437	chr19_18382703_+	ncRNA_intronic
CAediting_1319438	chr19_18382723_+	ncRNA_intronic
CAediting_1319439	chr19_18382731_+	ncRNA_intronic
CAediting_1319440	chr19_18382795_+	ncRNA_intronic
CAediting_1319441	chr19_18383467_+	ncRNA_intronic
CAediting_1319442	chr19_18383468_+	ncRNA_intronic
CAediting_1319443	chr19_18383513_+	ncRNA_intronic
CAediting_1319444	chr19_18383521_+	ncRNA_intronic
CAediting_1319445	chr19_18383547_+	ncRNA_intronic
CAediting_1319446	chr19_18383561_+	ncRNA_intronic
CAediting_1319447	chr19_18383576_+	ncRNA_intronic
CAediting_1319448	chr19_18383580_+	ncRNA_intronic
CAediting_1319449	chr19_18383612_+	ncRNA_intronic
CAediting_1319450	chr19_18383643_+	ncRNA_intronic
CAediting_1319451	chr19_18383772_+	ncRNA_intronic
CAediting_1319452	chr19_18383785_+	ncRNA_intronic
CAediting_1319453	chr19_18383791_+	ncRNA_intronic
CAediting_1319454	chr19_18383816_+	ncRNA_intronic
CAediting_1319455	chr19_18383817_+	ncRNA_intronic
CAediting_1319456	chr19_18383840_+	ncRNA_intronic
CAediting_1319457	chr19_18383861_+	ncRNA_intronic
CAediting_1319458	chr19_18383864_+	ncRNA_intronic
CAediting_1319459	chr19_18383867_+	ncRNA_intronic
CAediting_1319460	chr19_18383879_+	ncRNA_intronic
CAediting_1319461	chr19_18383883_+	ncRNA_intronic
CAediting_1319462	chr19_18383915_+	ncRNA_intronic
CAediting_1319463	chr19_18383919_+	ncRNA_intronic
CAediting_1319464	chr19_18383989_+	ncRNA_intronic
CAediting_1319465	chr19_18384168_+	ncRNA_intronic
CAediting_1319466	chr19_18384177_+	ncRNA_intronic
CAediting_1319467	chr19_18384239_+	ncRNA_intronic
CAediting_1319468	chr19_18384244_+	ncRNA_intronic
CAediting_1319469	chr19_18384254_+	ncRNA_intronic
CAediting_1319470	chr19_18384287_+	ncRNA_intronic
CAediting_1319471	chr19_18384291_+	ncRNA_intronic
CAediting_1319472	chr19_18384311_+	ncRNA_intronic
CAediting_1319473	chr19_18384313_+	ncRNA_intronic
CAediting_1319474	chr19_18384319_+	ncRNA_intronic
CAediting_1319475	chr19_18384323_+	ncRNA_intronic
CAediting_1319476	chr19_18384327_+	ncRNA_intronic
CAediting_1319477	chr19_18384340_+	ncRNA_intronic
CAediting_1319478	chr19_18384346_+	ncRNA_intronic
CAediting_1319479	chr19_18384348_+	ncRNA_intronic
CAediting_1319480	chr19_18384388_+	ncRNA_intronic
CAediting_1319481	chr19_18384431_+	ncRNA_intronic
CAediting_1319482	chr19_18384432_+	ncRNA_intronic
CAediting_1319483	chr19_18384436_+	ncRNA_intronic
CAediting_1319484	chr19_18384449_+	ncRNA_intronic
CAediting_1319485	chr19_18384461_+	ncRNA_intronic
CAediting_1319486	chr19_18384471_+	ncRNA_intronic
CAediting_1319487	chr19_18384473_+	ncRNA_intronic
CAediting_1319488	chr19_18384514_+	ncRNA_intronic
CAediting_1319489	chr19_18384523_+	ncRNA_intronic
CAediting_1319490	chr19_18384534_+	ncRNA_intronic
CAediting_1319491	chr19_18384543_+	ncRNA_intronic
CAediting_1319492	chr19_18384556_+	ncRNA_intronic
CAediting_1319493	chr19_18384568_+	ncRNA_intronic
CAediting_1319494	chr19_18384596_+	ncRNA_intronic
CAediting_1319495	chr19_18385021_+	ncRNA_intronic
CAediting_1319496	chr19_18385026_+	ncRNA_intronic
CAediting_1319497	chr19_18385036_+	ncRNA_intronic
CAediting_1319498	chr19_18385070_+	ncRNA_intronic
CAediting_1319499	chr19_18385071_+	ncRNA_intronic
CAediting_1319500	chr19_18385088_+	ncRNA_intronic
CAediting_1319501	chr19_18385133_+	ncRNA_intronic
CAediting_1319502	chr19_18385138_+	ncRNA_intronic
CAediting_1319503	chr19_18385142_+	ncRNA_intronic
CAediting_1319504	chr19_18385143_+	ncRNA_intronic
CAediting_1319505	chr19_18385156_+	ncRNA_intronic
CAediting_1319506	chr19_18385159_+	ncRNA_intronic
CAediting_1319507	chr19_18385165_+	ncRNA_intronic
CAediting_1319508	chr19_18385190_+	ncRNA_intronic
CAediting_1319509	chr19_18385195_+	ncRNA_intronic
CAediting_1319510	chr19_18385198_+	ncRNA_intronic
CAediting_1319511	chr19_18385210_+	ncRNA_intronic
CAediting_1319512	chr19_18385212_+	ncRNA_intronic
CAediting_1319513	chr19_18385215_+	ncRNA_intronic
CAediting_1319514	chr19_18385219_+	ncRNA_intronic
CAediting_1319515	chr19_18385236_+	ncRNA_intronic
CAediting_1319516	chr19_18385237_+	ncRNA_intronic
CAediting_1319517	chr19_18385238_+	ncRNA_intronic
CAediting_1319518	chr19_18385250_+	ncRNA_intronic
CAediting_1319519	chr19_18385344_+	ncRNA_intronic
CAediting_1319520	chr19_18385352_+	ncRNA_intronic
CAediting_1319521	chr19_18385356_+	ncRNA_intronic
CAediting_1319522	chr19_18385371_+	ncRNA_intronic
CAediting_1319523	chr19_18385383_+	ncRNA_intronic
CAediting_1319524	chr19_18385391_+	ncRNA_intronic
CAediting_1319525	chr19_18387046_+	ncRNA_intronic
CAediting_1319526	chr19_18387267_+	ncRNA_intronic
CAediting_1319527	chr19_18387273_+	ncRNA_intronic
CAediting_1319528	chr19_18387274_+	ncRNA_intronic
CAediting_1319529	chr19_18387287_+	ncRNA_intronic
CAediting_1319530	chr19_18387295_+	ncRNA_intronic
CAediting_1319531	chr19_18387296_+	ncRNA_intronic
CAediting_1319532	chr19_18387303_+	ncRNA_intronic
CAediting_1319533	chr19_18387314_+	ncRNA_intronic
CAediting_1319534	chr19_18387338_+	ncRNA_intronic
CAediting_1319535	chr19_18387343_+	ncRNA_intronic
CAediting_1319536	chr19_18387347_+	ncRNA_intronic
CAediting_1319537	chr19_18387363_+	ncRNA_intronic
CAediting_1319538	chr19_18387364_+	ncRNA_intronic
CAediting_1319539	chr19_18387379_+	ncRNA_intronic
CAediting_1319540	chr19_18387380_+	ncRNA_intronic
CAediting_1319541	chr19_18387383_+	ncRNA_intronic
CAediting_1319542	chr19_18387387_+	ncRNA_intronic
CAediting_1319543	chr19_18387389_+	ncRNA_intronic
CAediting_1319544	chr19_18387409_+	ncRNA_intronic
CAediting_1319545	chr19_18387423_+	ncRNA_intronic
CAediting_1319546	chr19_18387450_+	ncRNA_intronic
CAediting_1319547	chr19_18387455_+	ncRNA_intronic
CAediting_1319548	chr19_18387902_+	ncRNA_intronic
CAediting_1319549	chr19_18387921_+	ncRNA_intronic
CAediting_1319550	chr19_18387939_+	ncRNA_intronic
CAediting_1319551	chr19_18387961_+	ncRNA_intronic
CAediting_1319552	chr19_18387963_+	ncRNA_intronic
CAediting_1319553	chr19_18387970_+	ncRNA_intronic
CAediting_1319554	chr19_18387983_+	ncRNA_intronic
CAediting_1319555	chr19_18387987_+	ncRNA_intronic
CAediting_1319556	chr19_18388003_+	ncRNA_intronic
CAediting_1319557	chr19_18388006_+	ncRNA_intronic
CAediting_1319558	chr19_18388008_+	ncRNA_intronic
CAediting_1319559	chr19_18388009_+	ncRNA_intronic
CAediting_1319560	chr19_18388078_+	ncRNA_intronic
CAediting_1319561	chr19_18388095_+	ncRNA_intronic
CAediting_1319562	chr19_18388096_+	ncRNA_intronic
CAediting_1319563	chr19_18388097_+	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1319428	chr19_18375310_+	SINE	Alu	AluSx
CAediting_1319429	chr19_18375396_+	SINE	Alu	AluSx
CAediting_1319430	chr19_18382528_+	SINE	Alu	AluSx
CAediting_1319431	chr19_18382550_+	SINE	Alu	AluSx
CAediting_1319432	chr19_18382551_+	SINE	Alu	AluSx
CAediting_1319433	chr19_18382596_+	SINE	Alu	AluSx
CAediting_1319434	chr19_18382605_+	SINE	Alu	AluSx
CAediting_1319435	chr19_18382668_+	SINE	Alu	AluSx
CAediting_1319436	chr19_18382700_+	SINE	Alu	AluSx
CAediting_1319437	chr19_18382703_+	SINE	Alu	AluSx
CAediting_1319438	chr19_18382723_+	SINE	Alu	AluSx
CAediting_1319439	chr19_18382731_+	SINE	Alu	AluSx
CAediting_1319440	chr19_18382795_+	SINE	Alu	AluSx
CAediting_1319441	chr19_18383467_+	SINE	Alu	AluSx
CAediting_1319442	chr19_18383468_+	SINE	Alu	AluSx
CAediting_1319443	chr19_18383513_+	SINE	Alu	AluSx
CAediting_1319444	chr19_18383521_+	SINE	Alu	AluSx
CAediting_1319445	chr19_18383547_+	SINE	Alu	AluSx
CAediting_1319446	chr19_18383561_+	SINE	Alu	AluSx
CAediting_1319447	chr19_18383576_+	SINE	Alu	AluSx
CAediting_1319448	chr19_18383580_+	SINE	Alu	AluSx
CAediting_1319449	chr19_18383612_+	SINE	Alu	AluSx
CAediting_1319450	chr19_18383643_+	SINE	Alu	AluSx
CAediting_1319451	chr19_18383772_+	SINE	Alu	AluSz
CAediting_1319452	chr19_18383785_+	SINE	Alu	AluSz
CAediting_1319453	chr19_18383791_+	SINE	Alu	AluSz
CAediting_1319454	chr19_18383816_+	SINE	Alu	AluSz
CAediting_1319455	chr19_18383817_+	SINE	Alu	AluSz
CAediting_1319456	chr19_18383840_+	SINE	Alu	AluSz
CAediting_1319457	chr19_18383861_+	SINE	Alu	AluSz
CAediting_1319458	chr19_18383864_+	SINE	Alu	AluSz
CAediting_1319459	chr19_18383867_+	SINE	Alu	AluSz
CAediting_1319460	chr19_18383879_+	SINE	Alu	AluSz
CAediting_1319461	chr19_18383883_+	SINE	Alu	AluSz
CAediting_1319462	chr19_18383915_+	SINE	Alu	AluSz
CAediting_1319463	chr19_18383919_+	SINE	Alu	AluSz
CAediting_1319464	chr19_18383989_+	SINE	Alu	AluSz
CAediting_1319465	chr19_18384168_+	SINE	Alu	AluY
CAediting_1319466	chr19_18384177_+	SINE	Alu	AluY
CAediting_1319467	chr19_18384239_+	SINE	Alu	AluY
CAediting_1319468	chr19_18384244_+	SINE	Alu	AluY
CAediting_1319469	chr19_18384254_+	SINE	Alu	AluY
CAediting_1319470	chr19_18384287_+	SINE	Alu	AluY
CAediting_1319471	chr19_18384291_+	SINE	Alu	AluY
CAediting_1319472	chr19_18384311_+	SINE	Alu	AluY
CAediting_1319473	chr19_18384313_+	SINE	Alu	AluY
CAediting_1319474	chr19_18384319_+	SINE	Alu	AluY
CAediting_1319475	chr19_18384323_+	SINE	Alu	AluY
CAediting_1319476	chr19_18384327_+	SINE	Alu	AluY
CAediting_1319477	chr19_18384340_+	SINE	Alu	AluY
CAediting_1319478	chr19_18384346_+	SINE	Alu	AluY
CAediting_1319479	chr19_18384348_+	SINE	Alu	AluY
CAediting_1319480	chr19_18384388_+	SINE	Alu	AluSx
CAediting_1319481	chr19_18384431_+	SINE	Alu	AluSx
CAediting_1319482	chr19_18384432_+	SINE	Alu	AluSx
CAediting_1319483	chr19_18384436_+	SINE	Alu	AluSx
CAediting_1319484	chr19_18384449_+	SINE	Alu	AluSx
CAediting_1319485	chr19_18384461_+	SINE	Alu	AluSx
CAediting_1319486	chr19_18384471_+	SINE	Alu	AluSx
CAediting_1319487	chr19_18384473_+	SINE	Alu	AluSx
CAediting_1319488	chr19_18384514_+	SINE	Alu	AluSx
CAediting_1319489	chr19_18384523_+	SINE	Alu	AluSx
CAediting_1319490	chr19_18384534_+	SINE	Alu	AluSx
CAediting_1319491	chr19_18384543_+	SINE	Alu	AluSx
CAediting_1319492	chr19_18384556_+	SINE	Alu	AluSx
CAediting_1319493	chr19_18384568_+	SINE	Alu	AluSx
CAediting_1319494	chr19_18384596_+	SINE	Alu	AluSx
CAediting_1319495	chr19_18385021_+	SINE	Alu	AluSp
CAediting_1319496	chr19_18385026_+	SINE	Alu	AluSp
CAediting_1319497	chr19_18385036_+	SINE	Alu	AluSp
CAediting_1319498	chr19_18385070_+	SINE	Alu	AluSp
CAediting_1319499	chr19_18385071_+	SINE	Alu	AluSp
CAediting_1319500	chr19_18385088_+	SINE	Alu	AluSp
CAediting_1319501	chr19_18385133_+	SINE	Alu	AluSp
CAediting_1319502	chr19_18385138_+	SINE	Alu	AluSp
CAediting_1319503	chr19_18385142_+	SINE	Alu	AluSp
CAediting_1319504	chr19_18385143_+	SINE	Alu	AluSp
CAediting_1319505	chr19_18385156_+	SINE	Alu	AluSp
CAediting_1319506	chr19_18385159_+	SINE	Alu	AluSp
CAediting_1319507	chr19_18385165_+	SINE	Alu	AluSp
CAediting_1319508	chr19_18385190_+	SINE	Alu	AluSp
CAediting_1319509	chr19_18385195_+	SINE	Alu	AluSp
CAediting_1319510	chr19_18385198_+	SINE	Alu	AluSp
CAediting_1319511	chr19_18385210_+	SINE	Alu	AluSp
CAediting_1319512	chr19_18385212_+	SINE	Alu	AluSp
CAediting_1319513	chr19_18385215_+	SINE	Alu	AluSp
CAediting_1319514	chr19_18385219_+	SINE	Alu	AluSp
CAediting_1319515	chr19_18385236_+	SINE	Alu	AluSp
CAediting_1319516	chr19_18385237_+	SINE	Alu	AluSp
CAediting_1319517	chr19_18385238_+	SINE	Alu	AluSp
CAediting_1319518	chr19_18385250_+	SINE	Alu	AluSp
CAediting_1319519	chr19_18385344_+	SINE	Alu	FLAM_C
CAediting_1319520	chr19_18385352_+	SINE	Alu	FLAM_C
CAediting_1319521	chr19_18385356_+	SINE	Alu	FLAM_C
CAediting_1319522	chr19_18385371_+	SINE	Alu	FLAM_C
CAediting_1319523	chr19_18385383_+	SINE	Alu	FLAM_C
CAediting_1319524	chr19_18385391_+	SINE	Alu	FLAM_C
CAediting_1319526	chr19_18387267_+	SINE	Alu	AluJr
CAediting_1319527	chr19_18387273_+	SINE	Alu	AluJr
CAediting_1319528	chr19_18387274_+	SINE	Alu	AluJr
CAediting_1319529	chr19_18387287_+	SINE	Alu	AluJr
CAediting_1319530	chr19_18387295_+	SINE	Alu	AluJr
CAediting_1319531	chr19_18387296_+	SINE	Alu	AluJr
CAediting_1319532	chr19_18387303_+	SINE	Alu	AluJr
CAediting_1319533	chr19_18387314_+	SINE	Alu	AluJr
CAediting_1319534	chr19_18387338_+	SINE	Alu	AluJr
CAediting_1319535	chr19_18387343_+	SINE	Alu	AluJr
CAediting_1319536	chr19_18387347_+	SINE	Alu	AluJr
CAediting_1319537	chr19_18387363_+	SINE	Alu	AluJr
CAediting_1319538	chr19_18387364_+	SINE	Alu	AluJr
CAediting_1319539	chr19_18387379_+	SINE	Alu	AluJr
CAediting_1319540	chr19_18387380_+	SINE	Alu	AluJr
CAediting_1319541	chr19_18387383_+	SINE	Alu	AluJr
CAediting_1319542	chr19_18387387_+	SINE	Alu	AluJr
CAediting_1319543	chr19_18387389_+	SINE	Alu	AluJr
CAediting_1319544	chr19_18387409_+	SINE	Alu	AluJr
CAediting_1319545	chr19_18387423_+	SINE	Alu	AluJr
CAediting_1319546	chr19_18387450_+	SINE	Alu	AluJr
CAediting_1319547	chr19_18387455_+	SINE	Alu	AluJr
CAediting_1319548	chr19_18387902_+	SINE	Alu	AluSx1
CAediting_1319549	chr19_18387921_+	SINE	Alu	AluSx1
CAediting_1319550	chr19_18387939_+	SINE	Alu	AluSx1
CAediting_1319551	chr19_18387961_+	SINE	Alu	AluSx1
CAediting_1319552	chr19_18387963_+	SINE	Alu	AluSx1
CAediting_1319553	chr19_18387970_+	SINE	Alu	AluSx1
CAediting_1319554	chr19_18387983_+	SINE	Alu	AluSx1
CAediting_1319555	chr19_18387987_+	SINE	Alu	AluSx1
CAediting_1319556	chr19_18388003_+	SINE	Alu	AluSx1
CAediting_1319557	chr19_18388006_+	SINE	Alu	AluSx1
CAediting_1319558	chr19_18388008_+	SINE	Alu	AluSx1
CAediting_1319559	chr19_18388009_+	SINE	Alu	AluSx1
CAediting_1319560	chr19_18388078_+	SINE	Alu	AluSx1
CAediting_1319561	chr19_18388095_+	SINE	Alu	AluSx1
CAediting_1319562	chr19_18388096_+	SINE	Alu	AluSx1
CAediting_1319563	chr19_18388097_+	SINE	Alu	AluSx1

Top

RNA A-to-I editing events in the alternative splicing sites for GDF15

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	CAeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
ES	CAediting_1319430	chr19_18382528_+	18382509:18382531	3SS	0+1i	ATGTTCTTATTTGGGGGCCAGGC	-10.52	ATGTTCTTATTTGGGGGCCGGGC	-1.77
IR	CAediting_1319430	chr19_18382528_+	18382509:18382531	3SS	0+1i	ATGTTCTTATTTGGGGGCCAGGC	-10.52	ATGTTCTTATTTGGGGGCCGGGC	-1.77

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000130513.6.GDF15.

Correlation between RNA A-to-I editing and PSI for ENSG00000130513.6.GDF15.

Top

Differntial gene expression between RNA A-to-I edited versus non-edited samples for GDF15

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

PRAD.CAediting_1319529.ENSG00000130513.GDF15.png
Soverview

Top

Protein coding region RNA A-to-I editings for GDF15

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

Top

The effects of the RNA editing to the miRNA binding sites for GDF15

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_228905	chr2_188297554_+	ENSG00000130513.6	ENST00000252809	hsa-miR-561-3p	18389139	18389145	7mer-m8	18389125	18389146	153	-12.38

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for GDF15

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

Top

Relation with ADAR for GDF15

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
LUAD	CAediting_1319488	chr19_18384514_+	2.96949715019528e-05	0.549459406992677	.	.	.	.
LUAD	CAediting_1319508	chr19_18385190_+	0.0153013848637029	0.280998227833531	.	.	.	.
LUAD	CAediting_1319523	chr19_18385383_+	0.000569778813291534	0.379124487797827	.	.	.	.
LUAD	CAediting_1319529	chr19_18387287_+	0.0161439654561966	0.312002180877446	.	.	.	.
PRAD	CAediting_1319529	chr19_18387287_+	.	.	0.00231522422482055	0.233527454770357	.	.

Top

Relation with cancer stages for GDF15

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
BLCA	pathologic_stage	CAediting_1319544	chr19_18387409_+	0.00835309272233323	0.276436424240119
KIRC	pathologic_stage	CAediting_1319544	chr19_18387409_+	0.026758645450877	0.215166469524832

Top

Relation with survival for GDF15

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
LUAD	CAediting_1319529	chr19_18387287_+	0.0461302152578453	0.0226546	814.078
KIRC	CAediting_1319526	chr19_18387267_+	0.0486898637783478	0.020776	121.989

Top

RelatedDrugs for GDF15

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

RelatedDiseases for GDF15

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
GDF15	C0033578	Prostatic Neoplasms	2	CTD_human
GDF15	C0376358	Malignant neoplasm of prostate	2	CTD_human
GDF15	C0002896	Sideroblastic anemia	1	CTD_human
GDF15	C0006625	Cachexia	1	CTD_human
GDF15	C0010054	Coronary Arteriosclerosis	1	CTD_human
GDF15	C0017185	Gastrointestinal Neoplasms	1	CTD_human
GDF15	C0018801	Heart failure	1	CTD_human
GDF15	C0018802	Congestive heart failure	1	CTD_human
GDF15	C0023212	Left-Sided Heart Failure	1	CTD_human
GDF15	C0025202	melanoma	1	CTD_human
GDF15	C0026636	Mouth Diseases	1	CTD_human
GDF15	C0027627	Neoplasm Metastasis	1	CTD_human
GDF15	C0043094	Weight Gain	1	CTD_human
GDF15	C0149721	Left Ventricular Hypertrophy	1	CTD_human
GDF15	C0151744	Myocardial Ischemia	1	CTD_human
GDF15	C0235527	Heart Failure, Right-Sided	1	CTD_human
GDF15	C0685938	Malignant neoplasm of gastrointestinal tract	1	CTD_human
GDF15	C1956346	Coronary Artery Disease	1	CTD_human
GDF15	C1959583	Myocardial Failure	1	CTD_human
GDF15	C1961112	Heart Decompensation	1	CTD_human
GDF15	C2239176	Liver carcinoma	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene