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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: REEP6 (CAeditome ID:92840) |
Gene summary for REEP6 |
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Gene information | Gene symbol | REEP6 | Gene ID | 92840 |
Gene name | receptor accessory protein 6 | |
Synonyms | C19orf32|DP1L1|REEP6.1|REEP6.2|RP77|TB2L1|Yip2f | |
Cytomap | 19p13.3 | |
Type of gene | protein-coding | |
Description | receptor expression-enhancing protein 6deleted in polyposis 1-like 1polyposis locus protein 1-like 1 | |
Modification date | 20210518 | |
UniProtAcc | Q96HR9 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
REEP6 | GO:0001917 | Receptor expression-enhancing protein 6 | 27889058 |
REEP6 | GO:0005783 | Receptor expression-enhancing protein 6 | 0000052 |
REEP6 | GO:0005783 | Receptor expression-enhancing protein 6 | 27889058 |
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RNA A-to-I events for REEP6 |
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CAediting_1271224(1497466, +), |
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RNA editing positional annotations for REEP6 using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
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CAeditome ID | Position | Variant type |
CAediting_1271224 | chr19_1497466_+ | UTR3 |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
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RNA A-to-I editing events in the alternative splicing sites for REEP6 |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for REEP6 |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for REEP6 |
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The effects of the RNA editing to the miRNA binding sites for REEP6 |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_1271224 | chr19_1497466_+ | ENSG00000115255.9 | ENST00000233596 | hsa-miR-3173-5p | 1497463 | 1497469 | 7mer-m8 | 1497449 | 1497470 | 147 | -16.53 |
CAediting_1271224 | chr19_1497466_+ | ENSG00000115255.9 | ENST00000233596 | hsa-miR-6752-3p | 1497462 | 1497468 | 7mer-m8 | 1497449 | 1497469 | 140 | -14.1 |
CAediting_1271224 | chr19_1497466_+ | ENSG00000115255.9 | ENST00000233596 | hsa-miR-6799-3p | 1497463 | 1497469 | 7mer-m8 | 1497448 | 1497470 | 142 | -19.43 |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_748296 | chr10_51299626_+ | ENSG00000115255.9 | ENST00000233596 | hsa-miR-605-3p | 1497427 | 1497433 | 7mer-m8 | 1497408 | 1497434 | 147 | -24.65 |
CAediting_1054808 | chr15_66496985_- | ENSG00000115255.9 | ENST00000233596 | hsa-miR-4512 | 1497846 | 1497852 | 7mer-m8 | 1497833 | 1497853 | 146 | -18.43 |
CAediting_1368054 | chr19_46709310_- | ENSG00000115255.9 | ENST00000233596 | hsa-miR-320e | 1497403 | 1497409 | 7mer-m8 | 1497393 | 1497410 | 145 | -18.86 |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_604450 | chr7_133034877_- | ENSG00000115255.9 | ENST00000233596 | hsa-miR-3654 | 1497621 | 1497627 | 7mer-m8 | 1497608 | 1497628 | 152 | -21.05 |
CAediting_1054808 | chr15_66496985_- | ENSG00000115255.9 | ENST00000233596 | hsa-miR-4512 | 1497340 | 1497346 | 7mer-m8 | 1497325 | 1497347 | 148 | -26.44 |
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The effects of the RNA editing to the stability of the RNA structures for REEP6 |
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ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for REEP6 |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
BRCA | CAediting_1271224 | chr19_1497466_+ | 0.000168524732542573 | 0.362423954840282 | . | . | . | . |
LIHC | CAediting_1271224 | chr19_1497466_+ | 9.51208825505866e-06 | 0.46238370332388 | . | . | . | . |
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Relation with cancer stages for REEP6 |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
BRCA | pathologic_stage | CAediting_1271224 | chr19_1497466_+ | 0.0156533174897999 | 0.241143653090916 |
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Relation with survival for REEP6 |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for REEP6 |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for REEP6 |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |
REEP6 | C4310626 | RETINITIS PIGMENTOSA 77 | 4 | CTD_human;GENOMICS_ENGLAND;UNIPROT |
REEP6 | C0035334 | Retinitis Pigmentosa | 2 | GENOMICS_ENGLAND;ORPHANET |