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Editing gene: SLC16A7 (CAeditome ID:9194)

Gene summary for SLC16A7

Gene summary

Gene information	Gene symbol	SLC16A7
	Gene ID	9194
	Gene name	solute carrier family 16 member 7
	Synonyms	MCT2
	Cytomap	12q14.1
	Type of gene	protein-coding
	Description	monocarboxylate transporter 2solute carrier family 16 (monocarboxylate transporter), member 7solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
	Modification date	20210518
	UniProtAcc	O60669
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
SLC16A7	GO:0015129	Monocarboxylate transporter 2	9786900
SLC16A7	GO:0050833	Monocarboxylate transporter 2	9786900
SLC16A7	GO:1901475	Monocarboxylate transporter 2	9786900
SLC16A7	GO:0005654	Monocarboxylate transporter 2	0000052
SLC16A7	GO:0005886	Monocarboxylate transporter 2	0000052
SLC16A7	GO:0005887	Monocarboxylate transporter 2	15505343

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RNA A-to-I events for SLC16A7

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000118596.10

RNA A-to-I editing events in Cancer.

CAediting_901556(59614125, +), CAediting_901557(59614311, +), CAediting_901558(59614882, +), CAediting_901559(59666918, +), CAediting_901560(59666939, +), CAediting_901561(59713294, +), CAediting_901562(59716664, +), CAediting_901563(59724436, +), CAediting_901564(59746890, +), CAediting_901565(59747937, +), CAediting_901566(59783716, +), CAediting_901567(59783729, +), CAediting_901568(59783732, +), CAediting_901569(59783745, +), CAediting_901570(59783751, +), CAediting_901571(59783752, +), CAediting_901572(59783755, +), CAediting_901573(59783769, +), CAediting_901574(59783781, +), CAediting_901575(59783782, +), CAediting_901576(59783787, +), CAediting_901577(59783791, +), CAediting_901578(59783804, +), CAediting_901579(59783860, +), CAediting_901580(59783863, +), CAediting_901581(59783865, +), CAediting_901582(59783913, +), CAediting_901583(59784250, +), CAediting_901584(59784256, +), CAediting_901585(59784278, +), CAediting_901586(59784286, +), CAediting_901587(59784291, +), CAediting_901588(59784347, +), CAediting_901589(59784351, +), CAediting_901590(59785884, +),

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RNA editing positional annotations for SLC16A7 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_901556	chr12_59614125_+	intronic
CAediting_901557	chr12_59614311_+	intronic
CAediting_901558	chr12_59614882_+	intronic
CAediting_901559	chr12_59666918_+	intronic
CAediting_901560	chr12_59666939_+	intronic
CAediting_901561	chr12_59713294_+	ncRNA_intronic
CAediting_901562	chr12_59716664_+	ncRNA_intronic
CAediting_901563	chr12_59724436_+	ncRNA_intronic
CAediting_901564	chr12_59746890_+	ncRNA_intronic
CAediting_901565	chr12_59747937_+	ncRNA_intronic
CAediting_901566	chr12_59783716_+	UTR3
CAediting_901567	chr12_59783729_+	UTR3
CAediting_901568	chr12_59783732_+	UTR3
CAediting_901569	chr12_59783745_+	UTR3
CAediting_901570	chr12_59783751_+	UTR3
CAediting_901571	chr12_59783752_+	UTR3
CAediting_901572	chr12_59783755_+	UTR3
CAediting_901573	chr12_59783769_+	UTR3
CAediting_901574	chr12_59783781_+	UTR3
CAediting_901575	chr12_59783782_+	UTR3
CAediting_901576	chr12_59783787_+	UTR3
CAediting_901577	chr12_59783791_+	UTR3
CAediting_901578	chr12_59783804_+	UTR3
CAediting_901579	chr12_59783860_+	UTR3
CAediting_901580	chr12_59783863_+	UTR3
CAediting_901581	chr12_59783865_+	UTR3
CAediting_901582	chr12_59783913_+	UTR3
CAediting_901583	chr12_59784250_+	UTR3
CAediting_901584	chr12_59784256_+	UTR3
CAediting_901585	chr12_59784278_+	UTR3
CAediting_901586	chr12_59784286_+	UTR3
CAediting_901587	chr12_59784291_+	UTR3
CAediting_901588	chr12_59784347_+	UTR3
CAediting_901589	chr12_59784351_+	UTR3
CAediting_901590	chr12_59785884_+	UTR3

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_901556	chr12_59614125_+	SINE	Alu	AluSx1
CAediting_901557	chr12_59614311_+	SINE	Alu	AluSx1
CAediting_901558	chr12_59614882_+	SINE	Alu	AluYm1
CAediting_901559	chr12_59666918_+	LTR	ERVL-MaLR	THE1A
CAediting_901560	chr12_59666939_+	LTR	ERVL-MaLR	THE1A
CAediting_901561	chr12_59713294_+	SINE	Alu	AluSx1
CAediting_901562	chr12_59716664_+	SINE	Alu	AluJb
CAediting_901564	chr12_59746890_+	SINE	Alu	AluJo
CAediting_901565	chr12_59747937_+	SINE	Alu	AluSx1
CAediting_901566	chr12_59783716_+	SINE	Alu	AluSx
CAediting_901567	chr12_59783729_+	SINE	Alu	AluSx
CAediting_901568	chr12_59783732_+	SINE	Alu	AluSx
CAediting_901569	chr12_59783745_+	SINE	Alu	AluSx
CAediting_901570	chr12_59783751_+	SINE	Alu	AluSx
CAediting_901571	chr12_59783752_+	SINE	Alu	AluSx
CAediting_901572	chr12_59783755_+	SINE	Alu	AluSx
CAediting_901573	chr12_59783769_+	SINE	Alu	AluSx
CAediting_901574	chr12_59783781_+	SINE	Alu	AluSx
CAediting_901575	chr12_59783782_+	SINE	Alu	AluSx
CAediting_901576	chr12_59783787_+	SINE	Alu	AluSx
CAediting_901577	chr12_59783791_+	SINE	Alu	AluSx
CAediting_901578	chr12_59783804_+	SINE	Alu	AluSx
CAediting_901579	chr12_59783860_+	SINE	Alu	AluSx
CAediting_901580	chr12_59783863_+	SINE	Alu	AluSx
CAediting_901581	chr12_59783865_+	SINE	Alu	AluSx
CAediting_901582	chr12_59783913_+	SINE	Alu	AluSx
CAediting_901583	chr12_59784250_+	SINE	Alu	AluJr
CAediting_901584	chr12_59784256_+	SINE	Alu	AluJr
CAediting_901585	chr12_59784278_+	SINE	Alu	AluJr
CAediting_901586	chr12_59784286_+	SINE	Alu	AluJr
CAediting_901587	chr12_59784291_+	SINE	Alu	AluJr
CAediting_901588	chr12_59784347_+	SINE	Alu	AluJr
CAediting_901589	chr12_59784351_+	SINE	Alu	AluJr
CAediting_901590	chr12_59785884_+	LINE	L1	L1PA3

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RNA A-to-I editing events in the alternative splicing sites for SLC16A7

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000118596.10.SLC16A7.

Correlation between RNA A-to-I editing and PSI for ENSG00000118596.10.SLC16A7.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SLC16A7

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for SLC16A7

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for SLC16A7

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_901566	chr12_59783716_+	ENSG00000118596.10	ENST00000261187	hsa-miR-6529-3p	59783709	59783715	7mer-m8	59783694	59783716	148.00	-14.43
CAediting_901566	chr12_59783716_+	ENSG00000118596.10	ENST00000261187	hsa-miR-6889-3p	59783709	59783715	7mer-m8	59783697	59783716	154.00	-20.26
CAediting_901566	chr12_59783716_+	ENSG00000118596.10	ENST00000261187	hsa-miR-7157-3p	59783710	59783715	6mer	59783695	59783716	152.00	-27.38
CAediting_901566	chr12_59783716_+	ENSG00000118596.10	ENST00000261187	hsa-miR-873-3p	59783713	59783719	7mer-m8	59783698	59783720	144.00	-18.06
CAediting_901567	chr12_59783729_+	ENSG00000118596.10	ENST00000261187	hsa-miR-6516-5p	59783725	59783731	7mer-m8	59783707	59783732	155.00	-17.01
CAediting_901569	chr12_59783745_+	ENSG00000118596.10	ENST00000261187	hsa-miR-1247-3p	59783740	59783746	7mer-m8	59783725	59783747	152.00	-22.08
CAediting_901568	chr12_59783732_+	ENSG00000118596.10	ENST00000261187	hsa-miR-20b-3p	59783725	59783731	7mer-m8	59783711	59783732	147.00	-14.37
CAediting_901568	chr12_59783732_+	ENSG00000118596.10	ENST00000261187	hsa-miR-485-5p	59783729	59783735	7mer-m8	59783709	59783736	143.00	-23.47
CAediting_901568	chr12_59783732_+	ENSG00000118596.10	ENST00000261187	hsa-miR-6884-5p	59783729	59783735	7mer-m8	59783713	59783736	158.00	-25.51
CAediting_901574	chr12_59783781_+	ENSG00000118596.10	ENST00000261187	hsa-miR-4704-3p	59783778	59783784	7mer-m8	59783764	59783785	140.00	-13.10
CAediting_901574	chr12_59783781_+	ENSG00000118596.10	ENST00000261187	hsa-miR-668-3p	59783776	59783782	7mer-m8	59783761	59783783	150.00	-22.15
CAediting_901575	chr12_59783782_+	ENSG00000118596.10	ENST00000261187	hsa-miR-5690	59783778	59783784	7mer-m8	59783765	59783785	145.00	-16.75
CAediting_901578	chr12_59783804_+	ENSG00000118596.10	ENST00000261187	hsa-miR-6770-3p	59783800	59783806	7mer-m8	59783786	59783807	154.00	-19.20
CAediting_901578	chr12_59783804_+	ENSG00000118596.10	ENST00000261187	hsa-miR-6770-3p	59783800	59783806	7mer-m8	59783786	59783807	154.00	-19.20
CAediting_901578	chr12_59783804_+	ENSG00000118596.10	ENST00000261187	hsa-miR-6770-3p	59783800	59783806	7mer-m8	59783786	59783807	154.00	-19.20
CAediting_901585	chr12_59784278_+	ENSG00000118596.10	ENST00000261187	hsa-miR-340-3p	59784271	59784277	7mer-m8	59784256	59784278	159.00	-25.44
CAediting_901585	chr12_59784278_+	ENSG00000118596.10	ENST00000261187	hsa-miR-6827-3p	59784271	59784277	7mer-m8	59784259	59784278	147.00	-23.40
CAediting_901587	chr12_59784291_+	ENSG00000118596.10	ENST00000261187	hsa-miR-3136-3p	59784287	59784293	7mer-m8	59784273	59784294	143.00	-18.31
CAediting_901587	chr12_59784291_+	ENSG00000118596.10	ENST00000261187	hsa-miR-6724-5p	59784289	59784295	7mer-m8	59784274	59784296	141.00	-25.02
CAediting_901587	chr12_59784291_+	ENSG00000118596.10	ENST00000261187	hsa-miR-6724-5p	59784289	59784295	7mer-m8	59784274	59784296	141.00	-25.02
CAediting_901587	chr12_59784291_+	ENSG00000118596.10	ENST00000261187	hsa-miR-6724-5p	59784289	59784295	7mer-m8	59784274	59784296	141.00	-25.02
CAediting_901587	chr12_59784291_+	ENSG00000118596.10	ENST00000261187	hsa-miR-6724-5p	59784289	59784295	7mer-m8	59784274	59784296	141.00	-25.02
CAediting_901587	chr12_59784291_+	ENSG00000118596.10	ENST00000261187	hsa-miR-6773-5p	59784289	59784295	7mer-m8	59784274	59784296	149.00	-20.69
CAediting_901587	chr12_59784291_+	ENSG00000118596.10	ENST00000261187	hsa-miR-7155-3p	59784287	59784293	7mer-m8	59784274	59784294	148.00	-20.75

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_901587	chr12_59784291_+	ENSG00000118596.10	ENST00000261187	hsa-miR-10400-3p	59784289	59784295	7mer-m8	59784274	59784296	141	-23.02
CAediting_901575	chr12_59783782_+	ENSG00000118596.10	ENST00000261187	hsa-miR-145-5p	59783780	59783787	8mer-1a	59783766	59783787	147	-15.52
CAediting_901576	chr12_59783787_+	ENSG00000118596.10	ENST00000261187	hsa-miR-145-5p	59783780	59783787	8mer-1a	59783766	59783787	147	-15.52
CAediting_901572	chr12_59783755_+	ENSG00000118596.10	ENST00000261187	hsa-miR-219b-3p	59783752	59783758	7mer-m8	59783739	59783759	153	-15.53
CAediting_901572	chr12_59783755_+	ENSG00000118596.10	ENST00000261187	hsa-miR-302f	59783751	59783757	7mer-m8	59783742	59783758	147	-8.32
CAediting_901582	chr12_59783913_+	ENSG00000118596.10	ENST00000261187	hsa-miR-3622a-3p	59783910	59783917	8mer-1a	59783896	59783917	144	-13.55
CAediting_901582	chr12_59783913_+	ENSG00000118596.10	ENST00000261187	hsa-miR-3622b-3p	59783910	59783917	8mer-1a	59783897	59783917	152	-17.6
CAediting_901580	chr12_59783863_+	ENSG00000118596.10	ENST00000261187	hsa-miR-3675-3p	59783861	59783867	7mer-m8	59783847	59783868	145	-14.49
CAediting_901581	chr12_59783865_+	ENSG00000118596.10	ENST00000261187	hsa-miR-3675-3p	59783861	59783867	7mer-m8	59783847	59783868	145	-14.49
CAediting_901569	chr12_59783745_+	ENSG00000118596.10	ENST00000261187	hsa-miR-3689a-3p	59783738	59783744	7mer-m8	59783725	59783745	150	-22.19
CAediting_901587	chr12_59784291_+	ENSG00000118596.10	ENST00000261187	hsa-miR-372-5p	59784285	59784291	7mer-m8	59784270	59784292	145	-11.03
CAediting_901568	chr12_59783732_+	ENSG00000118596.10	ENST00000261187	hsa-miR-377-5p	59783729	59783735	7mer-m8	59783713	59783736	142	-15.73
CAediting_901587	chr12_59784291_+	ENSG00000118596.10	ENST00000261187	hsa-miR-4437	59784288	59784295	8mer-1a	59784275	59784295	146	-18.96
CAediting_901573	chr12_59783769_+	ENSG00000118596.10	ENST00000261187	hsa-miR-4478	59783766	59783772	7mer-m8	59783758	59783773	149	-25.05
CAediting_901573	chr12_59783769_+	ENSG00000118596.10	ENST00000261187	hsa-miR-4649-3p	59783763	59783769	7mer-m8	59783750	59783770	140	-14.11
CAediting_901587	chr12_59784291_+	ENSG00000118596.10	ENST00000261187	hsa-miR-4674	59784289	59784295	7mer-m8	59784274	59784296	148	-28.01
CAediting_901588	chr12_59784347_+	ENSG00000118596.10	ENST00000261187	hsa-miR-4774-3p	59784345	59784351	7mer-m8	59784329	59784352	146	-14.92
CAediting_901589	chr12_59784351_+	ENSG00000118596.10	ENST00000261187	hsa-miR-4774-3p	59784345	59784351	7mer-m8	59784329	59784352	146	-14.92
CAediting_901569	chr12_59783745_+	ENSG00000118596.10	ENST00000261187	hsa-miR-490-3p	59783742	59783748	7mer-m8	59783727	59783749	146	-16.15
CAediting_901566	chr12_59783716_+	ENSG00000118596.10	ENST00000261187	hsa-miR-5186	59783713	59783719	7mer-m8	59783700	59783720	140	-11.31
CAediting_901582	chr12_59783913_+	ENSG00000118596.10	ENST00000261187	hsa-miR-544b	59783908	59783914	7mer-m8	59783896	59783915	151	-18.19
CAediting_901568	chr12_59783732_+	ENSG00000118596.10	ENST00000261187	hsa-miR-6086	59783729	59783735	7mer-m8	59783715	59783736	148	-20.39
CAediting_901584	chr12_59784256_+	ENSG00000118596.10	ENST00000261187	hsa-miR-619-5p	59784251	59784256	6mer	59784236	59784257	154	-29.57
CAediting_901569	chr12_59783745_+	ENSG00000118596.10	ENST00000261187	hsa-miR-6779-5p	59783738	59783744	7mer-m8	59783727	59783745	152	-23.45
CAediting_901569	chr12_59783745_+	ENSG00000118596.10	ENST00000261187	hsa-miR-6780a-5p	59783738	59783744	7mer-m8	59783725	59783745	145	-20.2
CAediting_901569	chr12_59783745_+	ENSG00000118596.10	ENST00000261187	hsa-miR-6852-5p	59783741	59783746	6mer	59783727	59783747	140	-22.29
CAediting_901585	chr12_59784278_+	ENSG00000118596.10	ENST00000261187	hsa-miR-6892-3p	59784276	59784282	7mer-m8	59784259	59784283	143	-22.68
CAediting_901573	chr12_59783769_+	ENSG00000118596.10	ENST00000261187	hsa-miR-7160-5p	59783764	59783770	7mer-m8	59783751	59783771	147	-20.02
CAediting_901582	chr12_59783913_+	ENSG00000118596.10	ENST00000261187	hsa-miR-7162-3p	59783907	59783913	7mer-m8	59783895	59783914	142	-17.11
CAediting_901583	chr12_59784250_+	ENSG00000118596.10	ENST00000261187	hsa-miR-8052	59784249	59784255	7mer-1a	59784235	59784255	145	-20.71
CAediting_901574	chr12_59783781_+	ENSG00000118596.10	ENST00000261187	hsa-miR-935	59783778	59783784	7mer-m8	59783762	59783785	141	-18.15
CAediting_901575	chr12_59783782_+	ENSG00000118596.10	ENST00000261187	hsa-miR-935	59783778	59783784	7mer-m8	59783762	59783785	141	-18.15

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_688080	chr9_63819626_+	ENSG00000118596.10	ENST00000552432	hsa-miR-4477b	59779810	59779816	7mer-m8	59779797	59779817	145	-12.49
CAediting_748296	chr10_51299626_+	ENSG00000118596.10	ENST00000261187	hsa-miR-605-3p	59780935	59780941	7mer-m8	59780921	59780942	144	-15.81
CAediting_980496	chr14_31014685_-	ENSG00000118596.10	ENST00000261187	hsa-miR-624-3p	59789653	59789659	7mer-m8	59789638	59789660	145	-13.52
CAediting_393	chr1_1167164_+	ENSG00000118596.10	ENST00000261187	hsa-miR-200b-3p	59788150	59788157	8mer-1a	59788136	59788157	140	-10.75
CAediting_688080	chr9_63819626_+	ENSG00000118596.10	ENST00000261187	hsa-miR-4477b	59779810	59779816	7mer-m8	59779797	59779817	145	-12.49
CAediting_748296	chr10_51299626_+	ENSG00000118596.10	ENST00000550062	hsa-miR-605-3p	59734168	59734174	7mer-m8	59734154	59734175	146	-14.61
CAediting_1229414	chr17_67471546_+	ENSG00000118596.10	ENST00000261187	hsa-miR-548aa	59783892	59783898	7mer-m8	59783875	59783899	144	-12.97
CAediting_1229415	chr17_67471547_+	ENSG00000118596.10	ENST00000261187	hsa-miR-548aa	59783823	59783829	7mer-m8	59783804	59783830	165	-17.89
CAediting_1160181	chr17_7017644_-	ENSG00000118596.10	ENST00000261187	hsa-miR-195-3p	59782712	59782718	7mer-m8	59782700	59782719	145	-8.25
CAediting_1160181	chr17_7017644_-	ENSG00000118596.10	ENST00000261187	hsa-miR-195-3p	59789531	59789538	8mer-1a	59789517	59789538	146	-10.11
CAediting_117844	chr1_162342605_+	ENSG00000118596.10	ENST00000261187	hsa-miR-556-3p	59784347	59784353	7mer-m8	59784334	59784354	146	-11.59
CAediting_1399425	chr20_1392958_-	ENSG00000118596.10	ENST00000261187	hsa-miR-6869-5p	59783392	59783399	8mer-1a	59783376	59783399	146	-18.61
CAediting_228905	chr2_188297554_+	ENSG00000118596.10	ENST00000261187	hsa-miR-561-3p	59783900	59783905	6mer	59783883	59783906	158	-26.54
CAediting_228905	chr2_188297554_+	ENSG00000118596.10	ENST00000261187	hsa-miR-561-3p	59789346	59789352	7mer-m8	59789334	59789353	153	-11.51
CAediting_442554	chr5_154685830_+	ENSG00000118596.10	ENST00000261187	hsa-miR-1303	59781754	59781760	7mer-m8	59781743	59781761	147	-14.88
CAediting_604450	chr7_133034877_-	ENSG00000118596.10	ENST00000261187	hsa-miR-3654	59784337	59784343	7mer-m8	59784324	59784344	146	-21.37
CAediting_1229415	chr17_67471547_+	ENSG00000118596.10	ENST00000549033	hsa-miR-548aa	59775160	59775166	7mer-m8	59775143	59775167	148	-10.17
CAediting_77128	chr1_85133844_+	ENSG00000118596.10	ENST00000549033	hsa-miR-4423-3p	59775284	59775290	7mer-m8	59775272	59775291	149	-12.44
CAediting_228905	chr2_188297554_+	ENSG00000118596.10	ENST00000549033	hsa-miR-561-3p	59775373	59775379	7mer-m8	59775359	59775380	148	-9.41
CAediting_1229415	chr17_67471547_+	ENSG00000118596.10	ENST00000549928	hsa-miR-548aa	59775160	59775166	7mer-m8	59775143	59775167	148	-10.17
CAediting_77128	chr1_85133844_+	ENSG00000118596.10	ENST00000549928	hsa-miR-4423-3p	59775284	59775290	7mer-m8	59775272	59775291	149	-12.44
CAediting_228905	chr2_188297554_+	ENSG00000118596.10	ENST00000549928	hsa-miR-561-3p	59775373	59775379	7mer-m8	59775359	59775380	148	-9.41
CAediting_1524209	chrX_134546392_-	ENSG00000118596.10	ENST00000261187	hsa-miR-503-5p	59780959	59780964	6mer	59780943	59780965	144	-28.16
CAediting_468389	chr6_31355314_-	ENSG00000118596.10	ENST00000549033	hsa-miR-6891-5p	59775462	59775468	7mer-m8	59775451	59775469	157	-22.57
CAediting_468389	chr6_31355314_-	ENSG00000118596.10	ENST00000549928	hsa-miR-6891-5p	59775462	59775468	7mer-m8	59775451	59775469	157	-22.57

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_573001	chr7_92204086_-	ENSG00000118596.10	ENST00000261187	hsa-miR-1285-5p	59781396	59781402	7mer-m8	59781383	59781403	141	-11.72
CAediting_573000	chr7_92204081_-	ENSG00000118596.10	ENST00000261187	hsa-miR-1285-5p	59781396	59781402	7mer-m8	59781383	59781403	141	-11.72
CAediting_573001	chr7_92204086_-	ENSG00000118596.10	ENST00000261187	hsa-miR-1285-5p	59787025	59787031	7mer-m8	59787010	59787032	146	-14.6
CAediting_573000	chr7_92204081_-	ENSG00000118596.10	ENST00000261187	hsa-miR-1285-5p	59787025	59787031	7mer-m8	59787010	59787032	146	-14.6
CAediting_846604	chr11_93733708_-	ENSG00000118596.10	ENST00000261187	hsa-miR-1304-3p	59787845	59787851	7mer-m8	59787831	59787852	152	-21.06
CAediting_1160181	chr17_7017644_-	ENSG00000118596.10	ENST00000261187	hsa-miR-195-3p	59781071	59781077	7mer-m8	59781055	59781078	147	-9.48
CAediting_1160181	chr17_7017644_-	ENSG00000118596.10	ENST00000261187	hsa-miR-195-3p	59782201	59782208	8mer-1a	59782188	59782208	145	-10.23
CAediting_1160181	chr17_7017644_-	ENSG00000118596.10	ENST00000261187	hsa-miR-195-3p	59784859	59784866	8mer-1a	59784844	59784866	152	-12.05
CAediting_1160181	chr17_7017644_-	ENSG00000118596.10	ENST00000261187	hsa-miR-195-3p	59787088	59787094	7mer-m8	59787075	59787095	152	-10.78
CAediting_1160181	chr17_7017644_-	ENSG00000118596.10	ENST00000261187	hsa-miR-195-3p	59789391	59789398	8mer-1a	59789376	59789398	151	-7.64
CAediting_393	chr1_1167164_+	ENSG00000118596.10	ENST00000261187	hsa-miR-200b-3p	59787284	59787290	7mer-m8	59787272	59787291	141	-10.43
CAediting_393	chr1_1167164_+	ENSG00000118596.10	ENST00000261187	hsa-miR-200b-3p	59787628	59787634	7mer-m8	59787614	59787635	148	-9.51
CAediting_393	chr1_1167164_+	ENSG00000118596.10	ENST00000261187	hsa-miR-200b-3p	59789237	59789243	7mer-m8	59789225	59789244	149	-9.56
CAediting_1306324	chr19_13836464_-	ENSG00000118596.10	ENST00000261187	hsa-miR-27a-3p	59789106	59789112	7mer-m8	59789092	59789113	146	-13.31
CAediting_396018	chr5_1062918_-	ENSG00000118596.10	ENST00000261187	hsa-miR-4635	59787970	59787975	6mer	59787958	59787976	140	-17.88
CAediting_117844	chr1_162342605_+	ENSG00000118596.10	ENST00000261187	hsa-miR-556-3p	59782273	59782279	7mer-m8	59782258	59782280	147	-11.27
CAediting_228905	chr2_188297554_+	ENSG00000118596.10	ENST00000261187	hsa-miR-561-3p	59780986	59780993	8mer-1a	59780972	59780993	140	-7.71
CAediting_228905	chr2_188297554_+	ENSG00000118596.10	ENST00000261187	hsa-miR-561-3p	59787497	59787503	7mer-m8	59787483	59787504	152	-8.35
CAediting_228905	chr2_188297554_+	ENSG00000118596.10	ENST00000261187	hsa-miR-561-3p	59789413	59789420	8mer-1a	59789401	59789420	148	-6.71
CAediting_748296	chr10_51299626_+	ENSG00000118596.10	ENST00000261187	hsa-miR-605-3p	59788638	59788644	7mer-m8	59788624	59788645	152	-14.13
CAediting_468389	chr6_31355314_-	ENSG00000118596.10	ENST00000261187	hsa-miR-6891-5p	59787504	59787509	6mer	59787492	59787510	141	-17.75

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for SLC16A7

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for SLC16A7

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
KIRC	CAediting_901571	chr12_59783752_+	2.76536856444371e-05	0.488304610968817	0.00104906686755358	0.391603374145831	.	.
LUAD	CAediting_901583	chr12_59784250_+	0.00970739090887097	0.218662084708766	.	.	.	.
HNSC	CAediting_901583	chr12_59784250_+	0.00295659110947286	0.368565486216631	.	.	.	.
KIRC	CAediting_901583	chr12_59784250_+	2.61052216081553e-08	0.455050843633691	0.00748230081848164	0.228411580921177	.	.
KIRP	CAediting_901583	chr12_59784250_+	0.00136073562930975	0.343889224618887	.	.	.	.

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Relation with cancer stages for SLC16A7

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
KICH	pathologic_stage	CAediting_901583	chr12_59784250_+	0.0309415253692119	0.276588562586452
KIRP	pathologic_stage	CAediting_901583	chr12_59784250_+	0.0311820961353207	0.24740967014662

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Relation with survival for SLC16A7

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for SLC16A7

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
SLC16A7	O60669	DB00119	Pyruvic acid	Monocarboxylate transporter 2	SmallMoleculeDrug	approved\|investigational\|nutraceutical

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RelatedDiseases for SLC16A7

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
SLC16A7	C0028754	Obesity	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene