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Editing gene: PCSK7 (CAeditome ID:9159)

Gene summary for PCSK7

Gene summary

Gene information	Gene symbol	PCSK7
	Gene ID	9159
	Gene name	proprotein convertase subtilisin/kexin type 7
	Synonyms	LPC\|PC7\|PC8\|SPC7
	Cytomap	11q23.3
	Type of gene	protein-coding
	Description	proprotein convertase subtilisin/kexin type 7lymphoma proprotein convertaseprohormone convertase 7prohormone convertase PC7proprotein convertase 7proprotein convertase 8proprotein convertase PC7proprotein convertase subtilisin/kexin type 7 precurso
	Modification date	20210524
	UniProtAcc	Q16549
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
PCSK7	GO:0016485	Proprotein convertase subtilisin/kexin type 7	15606899
PCSK7	GO:0008233	Proprotein convertase subtilisin/kexin type 7	15606899
PCSK7	GO:0030173	Proprotein convertase subtilisin/kexin type 7	9341152

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RNA A-to-I events for PCSK7

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000160613.11

RNA A-to-I editing events in Cancer.

CAediting_853706(117210374, -), CAediting_853707(117210393, -), CAediting_853708(117210406, -), CAediting_853709(117210416, -), CAediting_853710(117210421, -), CAediting_853711(117210424, -), CAediting_853712(117210426, -), CAediting_853713(117210435, -), CAediting_853714(117210444, -), CAediting_853715(117210448, -), CAediting_853716(117210451, -), CAediting_853717(117210455, -), CAediting_853718(117210456, -), CAediting_853719(117210464, -), CAediting_853720(117210465, -), CAediting_853721(117210470, -), CAediting_853722(117210474, -), CAediting_853723(117210480, -), CAediting_853724(117210497, -), CAediting_853725(117210503, -), CAediting_853726(117210523, -), CAediting_853727(117210526, -), CAediting_853728(117210541, -), CAediting_853729(117210552, -), CAediting_853730(117210553, -), CAediting_853731(117210562, -), CAediting_853732(117210572, -), CAediting_853733(117210575, -), CAediting_853734(117210585, -), CAediting_853735(117210629, -), CAediting_853736(117210630, -), CAediting_853737(117210768, -), CAediting_853738(117210779, -), CAediting_853739(117210786, -), CAediting_853740(117210787, -), CAediting_853741(117210795, -), CAediting_853742(117210803, -), CAediting_853743(117210811, -), CAediting_853744(117210823, -), CAediting_853745(117210826, -), CAediting_853746(117210834, -), CAediting_853747(117210835, -), CAediting_853748(117210841, -), CAediting_853749(117210849, -), CAediting_853750(117210867, -), CAediting_853751(117210868, -), CAediting_853752(117210874, -), CAediting_853753(117210890, -), CAediting_853754(117210892, -), CAediting_853755(117210896, -), CAediting_853756(117210898, -), CAediting_853757(117210903, -), CAediting_853758(117210922, -), CAediting_853759(117210930, -), CAediting_853760(117210932, -), CAediting_853761(117210934, -), CAediting_853762(117211139, -), CAediting_853763(117211143, -), CAediting_853764(117211145, -), CAediting_853765(117211157, -), CAediting_853766(117211171, -), CAediting_853767(117211203, -), CAediting_853768(117211207, -), CAediting_853769(117211208, -), CAediting_853770(117211217, -), CAediting_853771(117211222, -), CAediting_853772(117211232, -), CAediting_853773(117211249, -), CAediting_853774(117211259, -), CAediting_853775(117211293, -), CAediting_853776(117211335, -), CAediting_853777(117211357, -), CAediting_853778(117211387, -), CAediting_853779(117211388, -), CAediting_853780(117212400, -), CAediting_853781(117212435, -), CAediting_853782(117212436, -), CAediting_853783(117212448, -), CAediting_853784(117212453, -), CAediting_853785(117212463, -), CAediting_853786(117212473, -), CAediting_853787(117212478, -), CAediting_853788(117212482, -), CAediting_853789(117212495, -), CAediting_853790(117212503, -), CAediting_853791(117212516, -), CAediting_853792(117212517, -), CAediting_853793(117212527, -), CAediting_853794(117212541, -), CAediting_853795(117212550, -), CAediting_853796(117212551, -), CAediting_853797(117212559, -), CAediting_853798(117212561, -), CAediting_853799(117212577, -), CAediting_853800(117212595, -), CAediting_853801(117212637, -), CAediting_853802(117212742, -), CAediting_853803(117212744, -), CAediting_853804(117212745, -), CAediting_853805(117212749, -), CAediting_853806(117212750, -), CAediting_853807(117212771, -), CAediting_853808(117212776, -), CAediting_853809(117212781, -), CAediting_853810(117212786, -), CAediting_853811(117212803, -), CAediting_853812(117212811, -), CAediting_853813(117212819, -), CAediting_853814(117212821, -), CAediting_853815(117212822, -), CAediting_853816(117212829, -), CAediting_853817(117212842, -), CAediting_853818(117212846, -), CAediting_853819(117212879, -), CAediting_853820(117212886, -), CAediting_853821(117212890, -), CAediting_853822(117212891, -), CAediting_853823(117212892, -), CAediting_853824(117212893, -), CAediting_853825(117212894, -), CAediting_853826(117212895, -), CAediting_853827(117212898, -), CAediting_853828(117212910, -), CAediting_853829(117213948, -), CAediting_853830(117213987, -), CAediting_853831(117213988, -), CAediting_853832(117214053, -), CAediting_853833(117214054, -), CAediting_853834(117214068, -), CAediting_853835(117214095, -), CAediting_853836(117214162, -), CAediting_853837(117214207, -), CAediting_853838(117214213, -), CAediting_853839(117214229, -), CAediting_853840(117214230, -), CAediting_853841(117214248, -), CAediting_853842(117215218, -), CAediting_853843(117215263, -), CAediting_853844(117215278, -), CAediting_853845(117215281, -), CAediting_853846(117215292, -), CAediting_853847(117215293, -), CAediting_853848(117215334, -), CAediting_853849(117215468, -), CAediting_853850(117215539, -), CAediting_853851(117215561, -), CAediting_853852(117215674, -), CAediting_853853(117215745, -), CAediting_853854(117215750, -), CAediting_853855(117215778, -), CAediting_853856(117215805, -), CAediting_853857(117215829, -), CAediting_853858(117215845, -), CAediting_853859(117215854, -), CAediting_853860(117215889, -), CAediting_853861(117215929, -), CAediting_853862(117215940, -), CAediting_853863(117215948, -), CAediting_853864(117215953, -), CAediting_853865(117215967, -), CAediting_853866(117216058, -), CAediting_853867(117216095, -), CAediting_853868(117216108, -), CAediting_853869(117216461, -), CAediting_853870(117216466, -), CAediting_853871(117216512, -), CAediting_853872(117216525, -), CAediting_853873(117216529, -), CAediting_853874(117216536, -), CAediting_853875(117216539, -), CAediting_853876(117216542, -), CAediting_853877(117216559, -), CAediting_853878(117216637, -), CAediting_853879(117216642, -), CAediting_853880(117216676, -), CAediting_853881(117219916, -), CAediting_853882(117220357, -), CAediting_853883(117220375, -),

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RNA editing positional annotations for PCSK7 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_853706	chr11_117210374_-	ncRNA_exonic
CAediting_853707	chr11_117210393_-	ncRNA_exonic
CAediting_853708	chr11_117210406_-	ncRNA_exonic
CAediting_853709	chr11_117210416_-	ncRNA_exonic
CAediting_853710	chr11_117210421_-	ncRNA_exonic
CAediting_853711	chr11_117210424_-	ncRNA_exonic
CAediting_853712	chr11_117210426_-	ncRNA_exonic
CAediting_853713	chr11_117210435_-	ncRNA_exonic
CAediting_853714	chr11_117210444_-	ncRNA_exonic
CAediting_853715	chr11_117210448_-	ncRNA_exonic
CAediting_853716	chr11_117210451_-	ncRNA_exonic
CAediting_853717	chr11_117210455_-	ncRNA_exonic
CAediting_853718	chr11_117210456_-	ncRNA_exonic
CAediting_853719	chr11_117210464_-	ncRNA_exonic
CAediting_853720	chr11_117210465_-	ncRNA_exonic
CAediting_853721	chr11_117210470_-	ncRNA_exonic
CAediting_853722	chr11_117210474_-	ncRNA_exonic
CAediting_853723	chr11_117210480_-	ncRNA_exonic
CAediting_853724	chr11_117210497_-	ncRNA_exonic
CAediting_853725	chr11_117210503_-	ncRNA_exonic
CAediting_853726	chr11_117210523_-	ncRNA_exonic
CAediting_853727	chr11_117210526_-	ncRNA_exonic
CAediting_853728	chr11_117210541_-	ncRNA_exonic
CAediting_853729	chr11_117210552_-	ncRNA_exonic
CAediting_853730	chr11_117210553_-	ncRNA_exonic
CAediting_853731	chr11_117210562_-	ncRNA_exonic
CAediting_853732	chr11_117210572_-	ncRNA_exonic
CAediting_853733	chr11_117210575_-	ncRNA_exonic
CAediting_853734	chr11_117210585_-	ncRNA_exonic
CAediting_853735	chr11_117210629_-	ncRNA_exonic
CAediting_853736	chr11_117210630_-	ncRNA_exonic
CAediting_853737	chr11_117210768_-	ncRNA_exonic
CAediting_853738	chr11_117210779_-	ncRNA_exonic
CAediting_853739	chr11_117210786_-	ncRNA_exonic
CAediting_853740	chr11_117210787_-	ncRNA_exonic
CAediting_853741	chr11_117210795_-	ncRNA_exonic
CAediting_853742	chr11_117210803_-	ncRNA_exonic
CAediting_853743	chr11_117210811_-	ncRNA_exonic
CAediting_853744	chr11_117210823_-	ncRNA_exonic
CAediting_853745	chr11_117210826_-	ncRNA_exonic
CAediting_853746	chr11_117210834_-	ncRNA_exonic
CAediting_853747	chr11_117210835_-	ncRNA_exonic
CAediting_853748	chr11_117210841_-	ncRNA_exonic
CAediting_853749	chr11_117210849_-	ncRNA_exonic
CAediting_853750	chr11_117210867_-	ncRNA_exonic
CAediting_853751	chr11_117210868_-	ncRNA_exonic
CAediting_853752	chr11_117210874_-	ncRNA_exonic
CAediting_853753	chr11_117210890_-	ncRNA_exonic
CAediting_853754	chr11_117210892_-	ncRNA_exonic
CAediting_853755	chr11_117210896_-	ncRNA_exonic
CAediting_853756	chr11_117210898_-	ncRNA_exonic
CAediting_853757	chr11_117210903_-	ncRNA_exonic
CAediting_853758	chr11_117210922_-	ncRNA_exonic
CAediting_853759	chr11_117210930_-	ncRNA_exonic
CAediting_853760	chr11_117210932_-	ncRNA_exonic
CAediting_853761	chr11_117210934_-	ncRNA_exonic
CAediting_853762	chr11_117211139_-	ncRNA_exonic
CAediting_853763	chr11_117211143_-	ncRNA_exonic
CAediting_853764	chr11_117211145_-	ncRNA_exonic
CAediting_853765	chr11_117211157_-	ncRNA_exonic
CAediting_853766	chr11_117211171_-	ncRNA_exonic
CAediting_853767	chr11_117211203_-	ncRNA_exonic
CAediting_853768	chr11_117211207_-	ncRNA_exonic
CAediting_853769	chr11_117211208_-	ncRNA_exonic
CAediting_853770	chr11_117211217_-	ncRNA_exonic
CAediting_853771	chr11_117211222_-	ncRNA_exonic
CAediting_853772	chr11_117211232_-	ncRNA_exonic
CAediting_853773	chr11_117211249_-	ncRNA_exonic
CAediting_853774	chr11_117211259_-	ncRNA_exonic
CAediting_853775	chr11_117211293_-	ncRNA_exonic
CAediting_853776	chr11_117211335_-	ncRNA_exonic
CAediting_853777	chr11_117211357_-	ncRNA_exonic
CAediting_853778	chr11_117211387_-	ncRNA_exonic
CAediting_853779	chr11_117211388_-	ncRNA_exonic
CAediting_853780	chr11_117212400_-	ncRNA_exonic
CAediting_853781	chr11_117212435_-	ncRNA_exonic
CAediting_853782	chr11_117212436_-	ncRNA_exonic
CAediting_853783	chr11_117212448_-	ncRNA_exonic
CAediting_853784	chr11_117212453_-	ncRNA_exonic
CAediting_853785	chr11_117212463_-	ncRNA_exonic
CAediting_853786	chr11_117212473_-	ncRNA_exonic
CAediting_853787	chr11_117212478_-	ncRNA_exonic
CAediting_853788	chr11_117212482_-	ncRNA_exonic
CAediting_853789	chr11_117212495_-	ncRNA_exonic
CAediting_853790	chr11_117212503_-	ncRNA_exonic
CAediting_853791	chr11_117212516_-	ncRNA_exonic
CAediting_853792	chr11_117212517_-	ncRNA_exonic
CAediting_853793	chr11_117212527_-	ncRNA_exonic
CAediting_853794	chr11_117212541_-	ncRNA_exonic
CAediting_853795	chr11_117212550_-	ncRNA_exonic
CAediting_853796	chr11_117212551_-	ncRNA_exonic
CAediting_853797	chr11_117212559_-	ncRNA_exonic
CAediting_853798	chr11_117212561_-	ncRNA_exonic
CAediting_853799	chr11_117212577_-	ncRNA_exonic
CAediting_853800	chr11_117212595_-	ncRNA_exonic
CAediting_853801	chr11_117212637_-	ncRNA_exonic
CAediting_853802	chr11_117212742_-	ncRNA_exonic
CAediting_853803	chr11_117212744_-	ncRNA_exonic
CAediting_853804	chr11_117212745_-	ncRNA_exonic
CAediting_853805	chr11_117212749_-	ncRNA_exonic
CAediting_853806	chr11_117212750_-	ncRNA_exonic
CAediting_853807	chr11_117212771_-	ncRNA_exonic
CAediting_853808	chr11_117212776_-	ncRNA_exonic
CAediting_853809	chr11_117212781_-	ncRNA_exonic
CAediting_853810	chr11_117212786_-	ncRNA_exonic
CAediting_853811	chr11_117212803_-	ncRNA_exonic
CAediting_853812	chr11_117212811_-	ncRNA_exonic
CAediting_853813	chr11_117212819_-	ncRNA_exonic
CAediting_853814	chr11_117212821_-	ncRNA_exonic
CAediting_853815	chr11_117212822_-	ncRNA_exonic
CAediting_853816	chr11_117212829_-	ncRNA_exonic
CAediting_853817	chr11_117212842_-	ncRNA_exonic
CAediting_853818	chr11_117212846_-	ncRNA_exonic
CAediting_853819	chr11_117212879_-	ncRNA_exonic
CAediting_853820	chr11_117212886_-	ncRNA_exonic
CAediting_853821	chr11_117212890_-	ncRNA_exonic
CAediting_853822	chr11_117212891_-	ncRNA_exonic
CAediting_853823	chr11_117212892_-	ncRNA_exonic
CAediting_853824	chr11_117212893_-	ncRNA_exonic
CAediting_853825	chr11_117212894_-	ncRNA_exonic
CAediting_853826	chr11_117212895_-	ncRNA_exonic
CAediting_853827	chr11_117212898_-	ncRNA_exonic
CAediting_853828	chr11_117212910_-	ncRNA_exonic
CAediting_853829	chr11_117213948_-	ncRNA_exonic
CAediting_853830	chr11_117213987_-	ncRNA_exonic
CAediting_853831	chr11_117213988_-	ncRNA_exonic
CAediting_853832	chr11_117214053_-	ncRNA_exonic
CAediting_853833	chr11_117214054_-	ncRNA_exonic
CAediting_853834	chr11_117214068_-	ncRNA_exonic
CAediting_853835	chr11_117214095_-	ncRNA_exonic
CAediting_853836	chr11_117214162_-	ncRNA_exonic
CAediting_853837	chr11_117214207_-	ncRNA_exonic
CAediting_853838	chr11_117214213_-	ncRNA_exonic
CAediting_853839	chr11_117214229_-	ncRNA_exonic
CAediting_853840	chr11_117214230_-	ncRNA_exonic
CAediting_853841	chr11_117214248_-	ncRNA_exonic
CAediting_853842	chr11_117215218_-	ncRNA_exonic
CAediting_853843	chr11_117215263_-	ncRNA_exonic
CAediting_853844	chr11_117215278_-	ncRNA_exonic
CAediting_853845	chr11_117215281_-	ncRNA_exonic
CAediting_853846	chr11_117215292_-	ncRNA_exonic
CAediting_853847	chr11_117215293_-	ncRNA_exonic
CAediting_853848	chr11_117215334_-	ncRNA_exonic
CAediting_853849	chr11_117215468_-	ncRNA_exonic
CAediting_853850	chr11_117215539_-	ncRNA_exonic
CAediting_853851	chr11_117215561_-	ncRNA_exonic
CAediting_853852	chr11_117215674_-	ncRNA_exonic
CAediting_853853	chr11_117215745_-	ncRNA_exonic
CAediting_853854	chr11_117215750_-	ncRNA_exonic
CAediting_853855	chr11_117215778_-	ncRNA_exonic
CAediting_853856	chr11_117215805_-	ncRNA_exonic
CAediting_853857	chr11_117215829_-	ncRNA_exonic
CAediting_853858	chr11_117215845_-	ncRNA_exonic
CAediting_853859	chr11_117215854_-	ncRNA_exonic
CAediting_853860	chr11_117215889_-	ncRNA_exonic
CAediting_853861	chr11_117215929_-	ncRNA_exonic
CAediting_853862	chr11_117215940_-	ncRNA_exonic
CAediting_853863	chr11_117215948_-	ncRNA_exonic
CAediting_853864	chr11_117215953_-	ncRNA_exonic
CAediting_853865	chr11_117215967_-	ncRNA_exonic
CAediting_853866	chr11_117216058_-	ncRNA_exonic
CAediting_853867	chr11_117216095_-	ncRNA_exonic
CAediting_853868	chr11_117216108_-	ncRNA_exonic
CAediting_853869	chr11_117216461_-	ncRNA_exonic
CAediting_853870	chr11_117216466_-	ncRNA_exonic
CAediting_853871	chr11_117216512_-	ncRNA_exonic
CAediting_853872	chr11_117216525_-	ncRNA_exonic
CAediting_853873	chr11_117216529_-	ncRNA_exonic
CAediting_853874	chr11_117216536_-	ncRNA_exonic
CAediting_853875	chr11_117216539_-	ncRNA_exonic
CAediting_853876	chr11_117216542_-	ncRNA_exonic
CAediting_853877	chr11_117216559_-	ncRNA_exonic
CAediting_853878	chr11_117216637_-	ncRNA_exonic
CAediting_853879	chr11_117216642_-	ncRNA_exonic
CAediting_853880	chr11_117216676_-	ncRNA_exonic
CAediting_853881	chr11_117219916_-	ncRNA_exonic
CAediting_853882	chr11_117220357_-	ncRNA_exonic
CAediting_853883	chr11_117220375_-	ncRNA_exonic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_853706	chr11_117210374_-	SINE	Alu	AluSc
CAediting_853707	chr11_117210393_-	SINE	Alu	AluSc
CAediting_853708	chr11_117210406_-	SINE	Alu	AluSc
CAediting_853709	chr11_117210416_-	SINE	Alu	AluSc
CAediting_853710	chr11_117210421_-	SINE	Alu	AluSc
CAediting_853711	chr11_117210424_-	SINE	Alu	AluSc
CAediting_853712	chr11_117210426_-	SINE	Alu	AluSc
CAediting_853713	chr11_117210435_-	SINE	Alu	AluSc
CAediting_853714	chr11_117210444_-	SINE	Alu	AluSc
CAediting_853715	chr11_117210448_-	SINE	Alu	AluSc
CAediting_853716	chr11_117210451_-	SINE	Alu	AluSc
CAediting_853717	chr11_117210455_-	SINE	Alu	AluSc
CAediting_853718	chr11_117210456_-	SINE	Alu	AluSc
CAediting_853719	chr11_117210464_-	SINE	Alu	AluSc
CAediting_853720	chr11_117210465_-	SINE	Alu	AluSc
CAediting_853721	chr11_117210470_-	SINE	Alu	AluSc
CAediting_853722	chr11_117210474_-	SINE	Alu	AluSc
CAediting_853723	chr11_117210480_-	SINE	Alu	AluSc
CAediting_853724	chr11_117210497_-	SINE	Alu	AluSc
CAediting_853725	chr11_117210503_-	SINE	Alu	AluSc
CAediting_853726	chr11_117210523_-	SINE	Alu	AluSc
CAediting_853727	chr11_117210526_-	SINE	Alu	AluSc
CAediting_853728	chr11_117210541_-	SINE	Alu	AluSc
CAediting_853729	chr11_117210552_-	SINE	Alu	AluSc
CAediting_853730	chr11_117210553_-	SINE	Alu	AluSc
CAediting_853731	chr11_117210562_-	SINE	Alu	AluSc
CAediting_853732	chr11_117210572_-	SINE	Alu	AluSc
CAediting_853733	chr11_117210575_-	SINE	Alu	AluSc
CAediting_853734	chr11_117210585_-	SINE	Alu	AluSc
CAediting_853735	chr11_117210629_-	SINE	Alu	AluSc
CAediting_853736	chr11_117210630_-	SINE	Alu	AluSc
CAediting_853737	chr11_117210768_-	SINE	Alu	AluSz6
CAediting_853738	chr11_117210779_-	SINE	Alu	AluSz6
CAediting_853739	chr11_117210786_-	SINE	Alu	AluSz6
CAediting_853740	chr11_117210787_-	SINE	Alu	AluSz6
CAediting_853741	chr11_117210795_-	SINE	Alu	AluSz6
CAediting_853742	chr11_117210803_-	SINE	Alu	AluSz6
CAediting_853743	chr11_117210811_-	SINE	Alu	AluSz6
CAediting_853744	chr11_117210823_-	SINE	Alu	AluSz6
CAediting_853745	chr11_117210826_-	SINE	Alu	AluSz6
CAediting_853746	chr11_117210834_-	SINE	Alu	AluSz6
CAediting_853747	chr11_117210835_-	SINE	Alu	AluSz6
CAediting_853748	chr11_117210841_-	SINE	Alu	AluSz6
CAediting_853749	chr11_117210849_-	SINE	Alu	AluSz6
CAediting_853750	chr11_117210867_-	SINE	Alu	AluSz6
CAediting_853751	chr11_117210868_-	SINE	Alu	AluSz6
CAediting_853752	chr11_117210874_-	SINE	Alu	AluSz6
CAediting_853753	chr11_117210890_-	SINE	Alu	AluSz6
CAediting_853754	chr11_117210892_-	SINE	Alu	AluSz6
CAediting_853755	chr11_117210896_-	SINE	Alu	AluSz6
CAediting_853756	chr11_117210898_-	SINE	Alu	AluSz6
CAediting_853757	chr11_117210903_-	SINE	Alu	AluSz6
CAediting_853758	chr11_117210922_-	SINE	Alu	AluSz6
CAediting_853759	chr11_117210930_-	SINE	Alu	AluSz6
CAediting_853760	chr11_117210932_-	SINE	Alu	AluSz6
CAediting_853761	chr11_117210934_-	SINE	Alu	AluSz6
CAediting_853762	chr11_117211139_-	SINE	Alu	AluSx
CAediting_853763	chr11_117211143_-	SINE	Alu	AluSx
CAediting_853764	chr11_117211145_-	SINE	Alu	AluSx
CAediting_853765	chr11_117211157_-	SINE	Alu	AluSx
CAediting_853766	chr11_117211171_-	SINE	Alu	AluSx
CAediting_853767	chr11_117211203_-	SINE	Alu	AluSx
CAediting_853768	chr11_117211207_-	SINE	Alu	AluSx
CAediting_853769	chr11_117211208_-	SINE	Alu	AluSx
CAediting_853770	chr11_117211217_-	SINE	Alu	AluSx
CAediting_853771	chr11_117211222_-	SINE	Alu	AluSx
CAediting_853772	chr11_117211232_-	SINE	Alu	AluSx
CAediting_853773	chr11_117211249_-	SINE	Alu	AluSx
CAediting_853774	chr11_117211259_-	SINE	Alu	AluSx
CAediting_853775	chr11_117211293_-	SINE	Alu	AluSx
CAediting_853776	chr11_117211335_-	SINE	Alu	AluSx
CAediting_853777	chr11_117211357_-	SINE	Alu	AluSx
CAediting_853778	chr11_117211387_-	SINE	Alu	AluSx
CAediting_853779	chr11_117211388_-	SINE	Alu	AluSx
CAediting_853780	chr11_117212400_-	SINE	Alu	AluSg
CAediting_853781	chr11_117212435_-	SINE	Alu	AluSg
CAediting_853782	chr11_117212436_-	SINE	Alu	AluSg
CAediting_853783	chr11_117212448_-	SINE	Alu	AluSg
CAediting_853784	chr11_117212453_-	SINE	Alu	AluSg
CAediting_853785	chr11_117212463_-	SINE	Alu	AluSg
CAediting_853786	chr11_117212473_-	SINE	Alu	AluSg
CAediting_853787	chr11_117212478_-	SINE	Alu	AluSg
CAediting_853788	chr11_117212482_-	SINE	Alu	AluSg
CAediting_853789	chr11_117212495_-	SINE	Alu	AluSg
CAediting_853790	chr11_117212503_-	SINE	Alu	AluSg
CAediting_853791	chr11_117212516_-	SINE	Alu	AluSg
CAediting_853792	chr11_117212517_-	SINE	Alu	AluSg
CAediting_853793	chr11_117212527_-	SINE	Alu	AluSg
CAediting_853794	chr11_117212541_-	SINE	Alu	AluSg
CAediting_853795	chr11_117212550_-	SINE	Alu	AluSg
CAediting_853796	chr11_117212551_-	SINE	Alu	AluSg
CAediting_853797	chr11_117212559_-	SINE	Alu	AluSg
CAediting_853798	chr11_117212561_-	SINE	Alu	AluSg
CAediting_853799	chr11_117212577_-	SINE	Alu	AluSg
CAediting_853800	chr11_117212595_-	SINE	Alu	AluSg
CAediting_853801	chr11_117212637_-	SINE	Alu	AluSg
CAediting_853802	chr11_117212742_-	SINE	Alu	AluSz6
CAediting_853803	chr11_117212744_-	SINE	Alu	AluSz6
CAediting_853804	chr11_117212745_-	SINE	Alu	AluSz6
CAediting_853805	chr11_117212749_-	SINE	Alu	AluSz6
CAediting_853806	chr11_117212750_-	SINE	Alu	AluSz6
CAediting_853807	chr11_117212771_-	SINE	Alu	AluSz6
CAediting_853808	chr11_117212776_-	SINE	Alu	AluSz6
CAediting_853809	chr11_117212781_-	SINE	Alu	AluSz6
CAediting_853810	chr11_117212786_-	SINE	Alu	AluSz6
CAediting_853811	chr11_117212803_-	SINE	Alu	AluSz6
CAediting_853812	chr11_117212811_-	SINE	Alu	AluSz6
CAediting_853813	chr11_117212819_-	SINE	Alu	AluSz6
CAediting_853814	chr11_117212821_-	SINE	Alu	AluSz6
CAediting_853815	chr11_117212822_-	SINE	Alu	AluSz6
CAediting_853816	chr11_117212829_-	SINE	Alu	AluSz6
CAediting_853817	chr11_117212842_-	SINE	Alu	AluSz6
CAediting_853818	chr11_117212846_-	SINE	Alu	AluSz6
CAediting_853819	chr11_117212879_-	SINE	Alu	AluSz6
CAediting_853820	chr11_117212886_-	SINE	Alu	AluSz6
CAediting_853821	chr11_117212890_-	SINE	Alu	AluSz6
CAediting_853822	chr11_117212891_-	SINE	Alu	AluSz6
CAediting_853823	chr11_117212892_-	SINE	Alu	AluSz6
CAediting_853824	chr11_117212893_-	SINE	Alu	AluSz6
CAediting_853825	chr11_117212894_-	SINE	Alu	AluSz6
CAediting_853826	chr11_117212895_-	SINE	Alu	AluSz6
CAediting_853827	chr11_117212898_-	SINE	Alu	AluSz6
CAediting_853828	chr11_117212910_-	SINE	Alu	AluSz6
CAediting_853829	chr11_117213948_-	SINE	Alu	AluSc
CAediting_853830	chr11_117213987_-	SINE	Alu	AluSc
CAediting_853831	chr11_117213988_-	SINE	Alu	AluSc
CAediting_853832	chr11_117214053_-	SINE	Alu	AluSc
CAediting_853833	chr11_117214054_-	SINE	Alu	AluSc
CAediting_853834	chr11_117214068_-	SINE	Alu	AluSc
CAediting_853835	chr11_117214095_-	SINE	Alu	AluSc
CAediting_853836	chr11_117214162_-	SINE	Alu	AluSc
CAediting_853837	chr11_117214207_-	SINE	Alu	AluSc
CAediting_853838	chr11_117214213_-	SINE	Alu	AluSc
CAediting_853839	chr11_117214229_-	SINE	Alu	AluSc
CAediting_853840	chr11_117214230_-	SINE	Alu	AluSc
CAediting_853841	chr11_117214248_-	SINE	Alu	AluSc
CAediting_853842	chr11_117215218_-	SINE	Alu	AluSz
CAediting_853843	chr11_117215263_-	SINE	Alu	AluSz
CAediting_853844	chr11_117215278_-	SINE	Alu	AluSz
CAediting_853845	chr11_117215281_-	SINE	Alu	AluSz
CAediting_853846	chr11_117215292_-	SINE	Alu	AluSz
CAediting_853847	chr11_117215293_-	SINE	Alu	AluSz
CAediting_853848	chr11_117215334_-	SINE	Alu	AluSz
CAediting_853849	chr11_117215468_-	SINE	Alu	AluY
CAediting_853850	chr11_117215539_-	SINE	Alu	AluY
CAediting_853851	chr11_117215561_-	SINE	Alu	AluY
CAediting_853852	chr11_117215674_-	SINE	Alu	AluY
CAediting_853853	chr11_117215745_-	SINE	Alu	AluSz
CAediting_853854	chr11_117215750_-	SINE	Alu	AluSz
CAediting_853855	chr11_117215778_-	SINE	Alu	AluSz
CAediting_853856	chr11_117215805_-	SINE	Alu	AluSz
CAediting_853857	chr11_117215829_-	SINE	Alu	AluSz
CAediting_853858	chr11_117215845_-	SINE	Alu	AluSz
CAediting_853859	chr11_117215854_-	SINE	Alu	AluSz
CAediting_853860	chr11_117215889_-	SINE	Alu	AluJo
CAediting_853861	chr11_117215929_-	SINE	Alu	AluJo
CAediting_853862	chr11_117215940_-	SINE	Alu	AluJo
CAediting_853863	chr11_117215948_-	SINE	Alu	AluJo
CAediting_853864	chr11_117215953_-	SINE	Alu	AluJo
CAediting_853865	chr11_117215967_-	SINE	Alu	AluJo
CAediting_853866	chr11_117216058_-	SINE	Alu	AluJo
CAediting_853867	chr11_117216095_-	SINE	Alu	AluJo
CAediting_853868	chr11_117216108_-	SINE	Alu	AluJo
CAediting_853869	chr11_117216461_-	SINE	Alu	AluSq2
CAediting_853870	chr11_117216466_-	SINE	Alu	AluSq2
CAediting_853871	chr11_117216512_-	SINE	Alu	AluSq2
CAediting_853872	chr11_117216525_-	SINE	Alu	AluSq2
CAediting_853873	chr11_117216529_-	SINE	Alu	AluSq2
CAediting_853874	chr11_117216536_-	SINE	Alu	AluSq2
CAediting_853875	chr11_117216539_-	SINE	Alu	AluSq2
CAediting_853876	chr11_117216542_-	SINE	Alu	AluSq2
CAediting_853877	chr11_117216559_-	SINE	Alu	AluSq2
CAediting_853878	chr11_117216637_-	SINE	Alu	AluSq2
CAediting_853879	chr11_117216642_-	SINE	Alu	AluSq2
CAediting_853880	chr11_117216676_-	SINE	Alu	AluSq2
CAediting_853881	chr11_117219916_-	SINE	Alu	FRAM
CAediting_853882	chr11_117220357_-	SINE	Alu	AluJr
CAediting_853883	chr11_117220375_-	SINE	Alu	AluJr

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RNA A-to-I editing events in the alternative splicing sites for PCSK7

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000160613.11.PCSK7.

Correlation between RNA A-to-I editing and PSI for ENSG00000160613.11.PCSK7.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PCSK7

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

LGG.CAediting_853747.ENSG00000160613.PCSK7.png
Soverview

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Protein coding region RNA A-to-I editings for PCSK7

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for PCSK7

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_980496	chr14_31014685_-	ENSG00000160613.11	ENST00000320934	hsa-miR-624-3p	117205290	117205296	7mer-m8	117205289	117205309	159	-18.93
CAediting_748296	chr10_51299626_+	ENSG00000160613.11	ENST00000540028	hsa-miR-605-3p	117206043	117206050	8mer-1a	117206043	117206064	143	-12.66
CAediting_980496	chr14_31014685_-	ENSG00000160613.11	ENST00000540028	hsa-miR-624-3p	117205290	117205296	7mer-m8	117205289	117205309	159	-18.93
CAediting_228905	chr2_188297554_+	ENSG00000160613.11	ENST00000320934	hsa-miR-561-3p	117204805	117204811	7mer-m8	117204804	117204826	153	-17.36
CAediting_396018	chr5_1062918_-	ENSG00000160613.11	ENST00000540028	hsa-miR-4635	117206681	117206687	7mer-m8	117206681	117206700	140	-9.98

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_468389	chr6_31355314_-	ENSG00000160613.11	ENST00000540028	hsa-miR-6891-5p	117206111	117206117	7mer-m8	117206110	117206129	148	-24.41

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for PCSK7

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for PCSK7

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
STAD	CAediting_853718	chr11_117210456_-	0.00933531606939418	0.294460305329379	.	.	.	.

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Relation with cancer stages for PCSK7

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
ESCA	pathologic_stage	CAediting_853712	chr11_117210426_-	0.0297072746577564	0.328053084590822
STAD	pathologic_stage	CAediting_853724	chr11_117210497_-	0.0163510234386838	0.231665976900511

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Relation with survival for PCSK7

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
STAD	CAediting_853814	chr11_117212821_-	0.00291560001997693	0.00609243	0.0504978

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RelatedDrugs for PCSK7

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for PCSK7

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene