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Editing gene: ZFAND2A (CAeditome ID:90637)

Gene summary for ZFAND2A

Gene summary

Gene information	Gene symbol	ZFAND2A
	Gene ID	90637
	Gene name	zinc finger AN1-type containing 2A
	Synonyms	AIRAP
	Cytomap	7p22.3
	Type of gene	protein-coding
	Description	AN1-type zinc finger protein 2Aarsenite inducible RNA associated proteinzinc finger, AN1-type domain 2A
	Modification date	20210518
	UniProtAcc	Q8N6M9
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for ZFAND2A

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000178381.10

RNA A-to-I editing events in Cancer.

CAediting_520194(1153315, -), CAediting_520195(1153331, -), CAediting_520196(1153333, -), CAediting_520197(1153337, -), CAediting_520198(1153345, -), CAediting_520199(1153350, -), CAediting_520200(1153356, -), CAediting_520201(1153362, -), CAediting_520202(1153363, -), CAediting_520203(1153369, -), CAediting_520204(1153376, -), CAediting_520205(1153379, -), CAediting_520206(1153382, -), CAediting_520207(1153408, -), CAediting_520208(1153411, -), CAediting_520209(1153412, -), CAediting_520210(1153413, -), CAediting_520211(1153418, -), CAediting_520212(1153420, -), CAediting_520213(1153439, -), CAediting_520214(1153440, -), CAediting_520215(1153448, -), CAediting_520216(1153457, -), CAediting_520217(1153460, -), CAediting_520218(1153479, -), CAediting_520219(1153492, -), CAediting_520220(1153493, -), CAediting_520221(1153498, -), CAediting_520222(1153506, -), CAediting_520223(1153509, -), CAediting_520224(1153514, -), CAediting_520225(1153686, -), CAediting_520226(1153688, -), CAediting_520227(1153701, -), CAediting_520228(1153724, -), CAediting_520229(1153728, -), CAediting_520230(1153762, -), CAediting_520231(1153822, -), CAediting_520232(1153824, -), CAediting_520233(1153827, -), CAediting_520234(1153834, -), CAediting_520235(1153837, -), CAediting_520236(1153846, -), CAediting_520237(1153859, -), CAediting_520238(1153860, -), CAediting_520239(1153863, -), CAediting_520240(1153884, -), CAediting_520241(1153889, -), CAediting_520242(1153941, -), CAediting_520243(1154875, -), CAediting_520244(1154885, -), CAediting_520245(1154901, -), CAediting_520246(1154938, -), CAediting_520247(1154946, -), CAediting_520248(1154950, -), CAediting_520249(1154952, -), CAediting_520250(1154961, -), CAediting_520251(1154974, -), CAediting_520252(1154983, -), CAediting_520253(1154996, -), CAediting_520254(1154999, -), CAediting_520255(1155006, -), CAediting_520256(1155009, -), CAediting_520257(1155018, -), CAediting_520258(1155031, -), CAediting_520259(1155035, -), CAediting_520260(1155055, -), CAediting_520261(1155056, -), CAediting_520262(1155117, -), CAediting_520263(1155121, -),

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RNA editing positional annotations for ZFAND2A using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_520194	chr7_1153315_-	ncRNA_intronic
CAediting_520195	chr7_1153331_-	ncRNA_intronic
CAediting_520196	chr7_1153333_-	ncRNA_intronic
CAediting_520197	chr7_1153337_-	ncRNA_intronic
CAediting_520198	chr7_1153345_-	ncRNA_intronic
CAediting_520199	chr7_1153350_-	ncRNA_intronic
CAediting_520200	chr7_1153356_-	ncRNA_intronic
CAediting_520201	chr7_1153362_-	ncRNA_intronic
CAediting_520202	chr7_1153363_-	ncRNA_intronic
CAediting_520203	chr7_1153369_-	ncRNA_intronic
CAediting_520204	chr7_1153376_-	ncRNA_intronic
CAediting_520205	chr7_1153379_-	ncRNA_intronic
CAediting_520206	chr7_1153382_-	ncRNA_intronic
CAediting_520207	chr7_1153408_-	ncRNA_intronic
CAediting_520208	chr7_1153411_-	ncRNA_intronic
CAediting_520209	chr7_1153412_-	ncRNA_intronic
CAediting_520210	chr7_1153413_-	ncRNA_intronic
CAediting_520211	chr7_1153418_-	ncRNA_intronic
CAediting_520212	chr7_1153420_-	ncRNA_intronic
CAediting_520213	chr7_1153439_-	ncRNA_intronic
CAediting_520214	chr7_1153440_-	ncRNA_intronic
CAediting_520215	chr7_1153448_-	ncRNA_intronic
CAediting_520216	chr7_1153457_-	ncRNA_intronic
CAediting_520217	chr7_1153460_-	ncRNA_intronic
CAediting_520218	chr7_1153479_-	ncRNA_intronic
CAediting_520219	chr7_1153492_-	ncRNA_intronic
CAediting_520220	chr7_1153493_-	ncRNA_intronic
CAediting_520221	chr7_1153498_-	ncRNA_intronic
CAediting_520222	chr7_1153506_-	ncRNA_intronic
CAediting_520223	chr7_1153509_-	ncRNA_intronic
CAediting_520224	chr7_1153514_-	ncRNA_intronic
CAediting_520225	chr7_1153686_-	ncRNA_intronic
CAediting_520226	chr7_1153688_-	ncRNA_intronic
CAediting_520227	chr7_1153701_-	ncRNA_intronic
CAediting_520228	chr7_1153724_-	ncRNA_intronic
CAediting_520229	chr7_1153728_-	ncRNA_intronic
CAediting_520230	chr7_1153762_-	ncRNA_intronic
CAediting_520231	chr7_1153822_-	ncRNA_intronic
CAediting_520232	chr7_1153824_-	ncRNA_intronic
CAediting_520233	chr7_1153827_-	ncRNA_intronic
CAediting_520234	chr7_1153834_-	ncRNA_intronic
CAediting_520235	chr7_1153837_-	ncRNA_intronic
CAediting_520236	chr7_1153846_-	ncRNA_intronic
CAediting_520237	chr7_1153859_-	ncRNA_intronic
CAediting_520238	chr7_1153860_-	ncRNA_intronic
CAediting_520239	chr7_1153863_-	ncRNA_intronic
CAediting_520240	chr7_1153884_-	ncRNA_intronic
CAediting_520241	chr7_1153889_-	ncRNA_intronic
CAediting_520242	chr7_1153941_-	ncRNA_intronic
CAediting_520243	chr7_1154875_-	ncRNA_intronic
CAediting_520244	chr7_1154885_-	ncRNA_intronic
CAediting_520245	chr7_1154901_-	ncRNA_intronic
CAediting_520246	chr7_1154938_-	ncRNA_intronic
CAediting_520247	chr7_1154946_-	ncRNA_intronic
CAediting_520248	chr7_1154950_-	ncRNA_intronic
CAediting_520249	chr7_1154952_-	ncRNA_intronic
CAediting_520250	chr7_1154961_-	ncRNA_intronic
CAediting_520251	chr7_1154974_-	ncRNA_intronic
CAediting_520252	chr7_1154983_-	ncRNA_intronic
CAediting_520253	chr7_1154996_-	ncRNA_intronic
CAediting_520254	chr7_1154999_-	ncRNA_intronic
CAediting_520255	chr7_1155006_-	ncRNA_intronic
CAediting_520256	chr7_1155009_-	ncRNA_intronic
CAediting_520257	chr7_1155018_-	ncRNA_intronic
CAediting_520258	chr7_1155031_-	ncRNA_intronic
CAediting_520259	chr7_1155035_-	ncRNA_intronic
CAediting_520260	chr7_1155055_-	ncRNA_intronic
CAediting_520261	chr7_1155056_-	ncRNA_intronic
CAediting_520262	chr7_1155117_-	ncRNA_intronic
CAediting_520263	chr7_1155121_-	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_520194	chr7_1153315_-	SINE	Alu	AluSz6
CAediting_520195	chr7_1153331_-	SINE	Alu	AluSz6
CAediting_520196	chr7_1153333_-	SINE	Alu	AluSz6
CAediting_520197	chr7_1153337_-	SINE	Alu	AluSz6
CAediting_520198	chr7_1153345_-	SINE	Alu	AluSz6
CAediting_520199	chr7_1153350_-	SINE	Alu	AluSz6
CAediting_520200	chr7_1153356_-	SINE	Alu	AluSz6
CAediting_520201	chr7_1153362_-	SINE	Alu	AluSz6
CAediting_520202	chr7_1153363_-	SINE	Alu	AluSz6
CAediting_520203	chr7_1153369_-	SINE	Alu	AluSz6
CAediting_520204	chr7_1153376_-	SINE	Alu	AluSz6
CAediting_520205	chr7_1153379_-	SINE	Alu	AluSz6
CAediting_520206	chr7_1153382_-	SINE	Alu	AluSz6
CAediting_520207	chr7_1153408_-	SINE	Alu	AluSz6
CAediting_520208	chr7_1153411_-	SINE	Alu	AluSz6
CAediting_520209	chr7_1153412_-	SINE	Alu	AluSz6
CAediting_520210	chr7_1153413_-	SINE	Alu	AluSz6
CAediting_520211	chr7_1153418_-	SINE	Alu	AluSz6
CAediting_520212	chr7_1153420_-	SINE	Alu	AluSz6
CAediting_520213	chr7_1153439_-	SINE	Alu	AluSz6
CAediting_520214	chr7_1153440_-	SINE	Alu	AluSz6
CAediting_520215	chr7_1153448_-	SINE	Alu	AluSz6
CAediting_520216	chr7_1153457_-	SINE	Alu	AluSz6
CAediting_520217	chr7_1153460_-	SINE	Alu	AluSz6
CAediting_520218	chr7_1153479_-	SINE	Alu	AluSz6
CAediting_520219	chr7_1153492_-	SINE	Alu	AluSz6
CAediting_520220	chr7_1153493_-	SINE	Alu	AluSz6
CAediting_520221	chr7_1153498_-	SINE	Alu	AluSz6
CAediting_520222	chr7_1153506_-	SINE	Alu	AluSz6
CAediting_520223	chr7_1153509_-	SINE	Alu	AluSz6
CAediting_520224	chr7_1153514_-	SINE	Alu	AluSz6
CAediting_520225	chr7_1153686_-	SINE	Alu	AluSx1
CAediting_520226	chr7_1153688_-	SINE	Alu	AluSx1
CAediting_520227	chr7_1153701_-	SINE	Alu	AluSx1
CAediting_520228	chr7_1153724_-	SINE	Alu	AluSx1
CAediting_520229	chr7_1153728_-	SINE	Alu	AluSx1
CAediting_520230	chr7_1153762_-	SINE	Alu	AluSx1
CAediting_520231	chr7_1153822_-	SINE	Alu	AluSx1
CAediting_520232	chr7_1153824_-	SINE	Alu	AluSx1
CAediting_520233	chr7_1153827_-	SINE	Alu	AluSx1
CAediting_520234	chr7_1153834_-	SINE	Alu	AluSx1
CAediting_520235	chr7_1153837_-	SINE	Alu	AluSx1
CAediting_520236	chr7_1153846_-	SINE	Alu	AluSx1
CAediting_520237	chr7_1153859_-	SINE	Alu	AluSx1
CAediting_520238	chr7_1153860_-	SINE	Alu	AluSx1
CAediting_520239	chr7_1153863_-	SINE	Alu	AluSx1
CAediting_520240	chr7_1153884_-	SINE	Alu	AluSx1
CAediting_520241	chr7_1153889_-	SINE	Alu	AluSx1
CAediting_520242	chr7_1153941_-	SINE	Alu	AluSx1
CAediting_520243	chr7_1154875_-	SINE	Alu	AluSg
CAediting_520244	chr7_1154885_-	SINE	Alu	AluSg
CAediting_520245	chr7_1154901_-	SINE	Alu	AluSg
CAediting_520246	chr7_1154938_-	SINE	Alu	AluSg
CAediting_520247	chr7_1154946_-	SINE	Alu	AluSg
CAediting_520248	chr7_1154950_-	SINE	Alu	AluSg
CAediting_520249	chr7_1154952_-	SINE	Alu	AluSg
CAediting_520250	chr7_1154961_-	SINE	Alu	AluSg
CAediting_520251	chr7_1154974_-	SINE	Alu	AluSg
CAediting_520252	chr7_1154983_-	SINE	Alu	AluSg
CAediting_520253	chr7_1154996_-	SINE	Alu	AluSg
CAediting_520254	chr7_1154999_-	SINE	Alu	AluSg
CAediting_520255	chr7_1155006_-	SINE	Alu	AluSg
CAediting_520256	chr7_1155009_-	SINE	Alu	AluSg
CAediting_520257	chr7_1155018_-	SINE	Alu	AluSg
CAediting_520258	chr7_1155031_-	SINE	Alu	AluSg
CAediting_520259	chr7_1155035_-	SINE	Alu	AluSg
CAediting_520260	chr7_1155055_-	SINE	Alu	AluSg
CAediting_520261	chr7_1155056_-	SINE	Alu	AluSg
CAediting_520262	chr7_1155117_-	SINE	Alu	AluSg
CAediting_520263	chr7_1155121_-	SINE	Alu	AluSg

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RNA A-to-I editing events in the alternative splicing sites for ZFAND2A

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	CAeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
IR	CAediting_520224	chr7_1153514_-	1153511:1153519	5SS	0+3i	AGGTAATCT	-13.24	AGGTAGTCT	-18.9

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000178381.10.ZFAND2A.

Correlation between RNA A-to-I editing and PSI for ENSG00000178381.10.ZFAND2A.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZFAND2A

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

PRAD.CAediting_520206.ENSG00000178381.ZFAND2A.png
Soverview

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Protein coding region RNA A-to-I editings for ZFAND2A

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for ZFAND2A

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ZFAND2A

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for ZFAND2A

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for ZFAND2A

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for ZFAND2A

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for ZFAND2A

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for ZFAND2A

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene