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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: ZNF468 (CAeditome ID:90333)

Gene summary for ZNF468

check button Gene summary
Gene informationGene symbol

ZNF468

Gene ID

90333

Gene namezinc finger protein 468
Synonyms-
Cytomap

19q13.41

Type of geneprotein-coding
Descriptionzinc finger protein 468zinc finger protein ZNF468
Modification date20210518
UniProtAcc

Q5VIY5

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for ZNF468

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000204604.8
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_1384688(52838999, -), CAediting_1384689(52839008, -), CAediting_1384690(52839009, -), CAediting_1384691(52839010, -), CAediting_1384692(52839017, -), CAediting_1384693(52839027, -), CAediting_1384694(52839057, -), CAediting_1384695(52839059, -), CAediting_1384696(52839063, -), CAediting_1384697(52839071, -), CAediting_1384698(52839085, -), CAediting_1384699(52839088, -), CAediting_1384700(52839112, -), CAediting_1384701(52839114, -), CAediting_1384702(52839143, -), CAediting_1384703(52839166, -), CAediting_1384704(52839169, -), CAediting_1384705(52839190, -), CAediting_1384706(52839208, -), CAediting_1384707(52839244, -), CAediting_1384708(52839306, -), CAediting_1384709(52839317, -), CAediting_1384710(52839344, -), CAediting_1384711(52839348, -), CAediting_1384712(52839353, -), CAediting_1384713(52839354, -), CAediting_1384714(52839360, -), CAediting_1384715(52839369, -), CAediting_1384716(52839374, -), CAediting_1384717(52839375, -), CAediting_1384718(52841142, -), CAediting_1384719(52842811, -), CAediting_1384720(52842956, -), CAediting_1384721(52842959, -), CAediting_1384722(52843061, -), CAediting_1384723(52843068, -), CAediting_1384724(52843069, -), CAediting_1384725(52843075, -), CAediting_1384726(52843876, -), CAediting_1384727(52844014, -), CAediting_1384728(52844022, -), CAediting_1384729(52844703, -), CAediting_1384730(52844706, -), CAediting_1384731(52845058, -), CAediting_1384732(52845113, -), CAediting_1384733(52845180, -), CAediting_1384734(52845182, -), CAediting_1384735(52845196, -), CAediting_1384736(52845204, -), CAediting_1384737(52845217, -), CAediting_1384738(52845218, -), CAediting_1384739(52845228, -), CAediting_1384740(52845257, -), CAediting_1384741(52845273, -), CAediting_1384742(52845645, -), CAediting_1384743(52845770, -), CAediting_1384744(52845793, -), CAediting_1384745(52845794, -), CAediting_1384746(52845807, -), CAediting_1384747(52845813, -), CAediting_1384748(52845833, -), CAediting_1384749(52845839, -), CAediting_1384750(52845881, -), CAediting_1384751(52845891, -), CAediting_1384752(52845894, -), CAediting_1384753(52845903, -), CAediting_1384754(52846306, -), CAediting_1384755(52846311, -), CAediting_1384756(52846324, -), CAediting_1384757(52846332, -), CAediting_1384758(52846364, -), CAediting_1384759(52846379, -), CAediting_1384760(52846394, -), CAediting_1384761(52846417, -), CAediting_1384762(52846418, -), CAediting_1384763(52846419, -), CAediting_1384764(52846432, -), CAediting_1384765(52846479, -), CAediting_1384766(52846481, -), CAediting_1384767(52846757, -), CAediting_1384768(52846758, -), CAediting_1384769(52846799, -), CAediting_1384770(52846835, -), CAediting_1384771(52846838, -), CAediting_1384772(52846853, -), CAediting_1384773(52846892, -), CAediting_1384774(52846944, -), CAediting_1384775(52846945, -), CAediting_1384776(52846957, -), CAediting_1384777(52846987, -), CAediting_1384778(52848615, -), CAediting_1384779(52848649, -), CAediting_1384780(52848689, -), CAediting_1384781(52848728, -), CAediting_1384782(52848778, -), CAediting_1384783(52852109, -), CAediting_1384784(52852121, -), CAediting_1384785(52852122, -), CAediting_1384786(52852199, -), CAediting_1384787(52852431, -), CAediting_1384788(52853579, -),

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RNA editing positional annotations for ZNF468 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred
CAediting_1384736chr19_52845204_-nonsynonymous SNVENST00000243639.7c.A235Gp.S79GD.D
CAediting_1384736chr19_52845204_-nonsynonymous SNVENST00000601847.1c.A127Gp.S43GD.D

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_1384688chr19_52838999_-UTR3
CAediting_1384689chr19_52839008_-UTR3
CAediting_1384690chr19_52839009_-UTR3
CAediting_1384691chr19_52839010_-UTR3
CAediting_1384692chr19_52839017_-UTR3
CAediting_1384693chr19_52839027_-UTR3
CAediting_1384694chr19_52839057_-UTR3
CAediting_1384695chr19_52839059_-UTR3
CAediting_1384696chr19_52839063_-UTR3
CAediting_1384697chr19_52839071_-UTR3
CAediting_1384698chr19_52839085_-UTR3
CAediting_1384699chr19_52839088_-UTR3
CAediting_1384700chr19_52839112_-UTR3
CAediting_1384701chr19_52839114_-UTR3
CAediting_1384702chr19_52839143_-UTR3
CAediting_1384703chr19_52839166_-UTR3
CAediting_1384704chr19_52839169_-UTR3
CAediting_1384705chr19_52839190_-UTR3
CAediting_1384706chr19_52839208_-UTR3
CAediting_1384707chr19_52839244_-UTR3
CAediting_1384708chr19_52839306_-UTR3
CAediting_1384709chr19_52839317_-UTR3
CAediting_1384710chr19_52839344_-UTR3
CAediting_1384711chr19_52839348_-UTR3
CAediting_1384712chr19_52839353_-UTR3
CAediting_1384713chr19_52839354_-UTR3
CAediting_1384714chr19_52839360_-UTR3
CAediting_1384715chr19_52839369_-UTR3
CAediting_1384716chr19_52839374_-UTR3
CAediting_1384717chr19_52839375_-UTR3
CAediting_1384718chr19_52841142_-exonic
CAediting_1384719chr19_52842811_-intronic
CAediting_1384720chr19_52842956_-intronic
CAediting_1384721chr19_52842959_-intronic
CAediting_1384722chr19_52843061_-intronic
CAediting_1384723chr19_52843068_-intronic
CAediting_1384724chr19_52843069_-intronic
CAediting_1384725chr19_52843075_-intronic
CAediting_1384726chr19_52843876_-intronic
CAediting_1384727chr19_52844014_-intronic
CAediting_1384728chr19_52844022_-intronic
CAediting_1384729chr19_52844703_-intronic
CAediting_1384730chr19_52844706_-intronic
CAediting_1384731chr19_52845058_-intronic
CAediting_1384732chr19_52845113_-intronic
CAediting_1384733chr19_52845180_-exonic
CAediting_1384734chr19_52845182_-exonic
CAediting_1384735chr19_52845196_-exonic
CAediting_1384736chr19_52845204_-exonic
CAediting_1384737chr19_52845217_-exonic
CAediting_1384738chr19_52845218_-exonic
CAediting_1384739chr19_52845228_-exonic
CAediting_1384740chr19_52845257_-exonic
CAediting_1384741chr19_52845273_-exonic
CAediting_1384742chr19_52845645_-intronic
CAediting_1384743chr19_52845770_-intronic
CAediting_1384744chr19_52845793_-intronic
CAediting_1384745chr19_52845794_-intronic
CAediting_1384746chr19_52845807_-intronic
CAediting_1384747chr19_52845813_-intronic
CAediting_1384748chr19_52845833_-intronic
CAediting_1384749chr19_52845839_-intronic
CAediting_1384750chr19_52845881_-intronic
CAediting_1384751chr19_52845891_-intronic
CAediting_1384752chr19_52845894_-intronic
CAediting_1384753chr19_52845903_-intronic
CAediting_1384754chr19_52846306_-intronic
CAediting_1384755chr19_52846311_-intronic
CAediting_1384756chr19_52846324_-intronic
CAediting_1384757chr19_52846332_-intronic
CAediting_1384758chr19_52846364_-intronic
CAediting_1384759chr19_52846379_-intronic
CAediting_1384760chr19_52846394_-intronic
CAediting_1384761chr19_52846417_-intronic
CAediting_1384762chr19_52846418_-intronic
CAediting_1384763chr19_52846419_-intronic
CAediting_1384764chr19_52846432_-intronic
CAediting_1384765chr19_52846479_-intronic
CAediting_1384766chr19_52846481_-intronic
CAediting_1384767chr19_52846757_-intronic
CAediting_1384768chr19_52846758_-intronic
CAediting_1384769chr19_52846799_-intronic
CAediting_1384770chr19_52846835_-intronic
CAediting_1384771chr19_52846838_-intronic
CAediting_1384772chr19_52846853_-intronic
CAediting_1384773chr19_52846892_-intronic
CAediting_1384774chr19_52846944_-intronic
CAediting_1384775chr19_52846945_-intronic
CAediting_1384776chr19_52846957_-intronic
CAediting_1384777chr19_52846987_-intronic
CAediting_1384778chr19_52848615_-intronic
CAediting_1384779chr19_52848649_-intronic
CAediting_1384780chr19_52848689_-intronic
CAediting_1384781chr19_52848728_-intronic
CAediting_1384782chr19_52848778_-intronic
CAediting_1384783chr19_52852109_-intronic
CAediting_1384784chr19_52852121_-intronic
CAediting_1384785chr19_52852122_-intronic
CAediting_1384786chr19_52852199_-intronic
CAediting_1384787chr19_52852431_-intronic
CAediting_1384788chr19_52853579_-intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_1384688chr19_52838999_-SINEAluAluSc8
CAediting_1384689chr19_52839008_-SINEAluAluSc8
CAediting_1384690chr19_52839009_-SINEAluAluSc8
CAediting_1384691chr19_52839010_-SINEAluAluSc8
CAediting_1384692chr19_52839017_-SINEAluAluSc8
CAediting_1384693chr19_52839027_-SINEAluAluSc8
CAediting_1384694chr19_52839057_-SINEAluAluSc8
CAediting_1384695chr19_52839059_-SINEAluAluSc8
CAediting_1384696chr19_52839063_-SINEAluAluSc8
CAediting_1384697chr19_52839071_-SINEAluAluSc8
CAediting_1384698chr19_52839085_-SINEAluAluSc8
CAediting_1384699chr19_52839088_-SINEAluAluSc8
CAediting_1384700chr19_52839112_-SINEAluAluSc8
CAediting_1384701chr19_52839114_-SINEAluAluSc8
CAediting_1384702chr19_52839143_-SINEAluAluSc8
CAediting_1384703chr19_52839166_-SINEAluAluSc8
CAediting_1384704chr19_52839169_-SINEAluAluSc8
CAediting_1384705chr19_52839190_-SINEAluAluSc8
CAediting_1384706chr19_52839208_-SINEAluAluSc8
CAediting_1384707chr19_52839244_-SINEAluAluSc8
CAediting_1384708chr19_52839306_-SINEAluAluSx
CAediting_1384709chr19_52839317_-SINEAluAluSx
CAediting_1384710chr19_52839344_-SINEAluAluSx
CAediting_1384711chr19_52839348_-SINEAluAluSx
CAediting_1384712chr19_52839353_-SINEAluAluSx
CAediting_1384713chr19_52839354_-SINEAluAluSx
CAediting_1384714chr19_52839360_-SINEAluAluSx
CAediting_1384715chr19_52839369_-SINEAluAluSx
CAediting_1384716chr19_52839374_-SINEAluAluSx
CAediting_1384717chr19_52839375_-SINEAluAluSx
CAediting_1384719chr19_52842811_-SINEAluAluSx4
CAediting_1384720chr19_52842956_-SINEAluAluSx1
CAediting_1384721chr19_52842959_-SINEAluAluSx1
CAediting_1384722chr19_52843061_-SINEAluAluSx1
CAediting_1384723chr19_52843068_-SINEAluAluSx1
CAediting_1384724chr19_52843069_-SINEAluAluSx1
CAediting_1384725chr19_52843075_-SINEAluAluSx1
CAediting_1384726chr19_52843876_-SINEAluAluSx1
CAediting_1384727chr19_52844014_-SINEAluAluSx1
CAediting_1384728chr19_52844022_-SINEAluAluSx1
CAediting_1384729chr19_52844703_-SINEAluAluSz
CAediting_1384730chr19_52844706_-SINEAluAluSz
CAediting_1384731chr19_52845058_-SINEAluAluSc8
CAediting_1384732chr19_52845113_-SINEAluAluSc8
CAediting_1384733chr19_52845180_-SINEAluAluSc8
CAediting_1384734chr19_52845182_-SINEAluAluSc8
CAediting_1384735chr19_52845196_-SINEAluAluSc8
CAediting_1384736chr19_52845204_-SINEAluAluSc8
CAediting_1384737chr19_52845217_-SINEAluAluSc8
CAediting_1384738chr19_52845218_-SINEAluAluSc8
CAediting_1384739chr19_52845228_-SINEAluAluSc8
CAediting_1384740chr19_52845257_-SINEAluAluSc8
CAediting_1384741chr19_52845273_-SINEAluAluSc8
CAediting_1384742chr19_52845645_-SINEAluAluSc
CAediting_1384743chr19_52845770_-SINEAluAluSp
CAediting_1384744chr19_52845793_-SINEAluAluSp
CAediting_1384745chr19_52845794_-SINEAluAluSp
CAediting_1384746chr19_52845807_-SINEAluAluSp
CAediting_1384747chr19_52845813_-SINEAluAluSp
CAediting_1384748chr19_52845833_-SINEAluAluSp
CAediting_1384749chr19_52845839_-SINEAluAluSp
CAediting_1384750chr19_52845881_-SINEAluAluSp
CAediting_1384751chr19_52845891_-SINEAluAluSp
CAediting_1384752chr19_52845894_-SINEAluAluSp
CAediting_1384753chr19_52845903_-SINEAluAluSp
CAediting_1384754chr19_52846306_-SINEAluAluSx1
CAediting_1384755chr19_52846311_-SINEAluAluSx1
CAediting_1384756chr19_52846324_-SINEAluAluSx1
CAediting_1384757chr19_52846332_-SINEAluAluSx1
CAediting_1384758chr19_52846364_-SINEAluAluSx1
CAediting_1384759chr19_52846379_-SINEAluAluSx1
CAediting_1384760chr19_52846394_-SINEAluAluSx1
CAediting_1384761chr19_52846417_-SINEAluAluSx1
CAediting_1384762chr19_52846418_-SINEAluAluSx1
CAediting_1384763chr19_52846419_-SINEAluAluSx1
CAediting_1384764chr19_52846432_-SINEAluAluSx1
CAediting_1384765chr19_52846479_-SINEAluAluSx1
CAediting_1384766chr19_52846481_-SINEAluAluSx1
CAediting_1384767chr19_52846757_-SINEAluAluSz
CAediting_1384768chr19_52846758_-SINEAluAluSz
CAediting_1384769chr19_52846799_-SINEAluAluSz
CAediting_1384770chr19_52846835_-SINEAluAluSz
CAediting_1384771chr19_52846838_-SINEAluAluSz
CAediting_1384772chr19_52846853_-SINEAluAluSz
CAediting_1384773chr19_52846892_-SINEAluAluSz
CAediting_1384774chr19_52846944_-SINEAluAluSz
CAediting_1384775chr19_52846945_-SINEAluAluSz
CAediting_1384776chr19_52846957_-SINEAluAluSz
CAediting_1384777chr19_52846987_-SINEAluAluSz
CAediting_1384778chr19_52848615_-SINEAluAluSz
CAediting_1384779chr19_52848649_-SINEAluAluSz
CAediting_1384780chr19_52848689_-SINEAluAluSz
CAediting_1384781chr19_52848728_-SINEAluAluSz
CAediting_1384782chr19_52848778_-SINEAluAluSz
CAediting_1384783chr19_52852109_-SINEAluAluSq2
CAediting_1384784chr19_52852121_-SINEAluAluSq2
CAediting_1384785chr19_52852122_-SINEAluAluSq2
CAediting_1384786chr19_52852199_-SINEAluAluSq2
CAediting_1384787chr19_52852431_-SINEAluAluSg7
CAediting_1384788chr19_52853579_-SINEAluAluSx

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RNA A-to-I editing events in the alternative splicing sites for ZNF468

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESCAediting_1384733chr19_52845180_-52845172:528451805SS3+0iAGGTGAGTG-15.24GGGTGAGTG-17.09

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000204604.8.ZNF468.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000204604.8.ZNF468.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZNF468

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for ZNF468

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.
all structure


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The effects of the RNA editing to the miRNA binding sites for ZNF468

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1384689chr19_52839008_-ENSG00000204604.8ENST00000243639hsa-miR-3189-3p52839007528390137mer-m85283900652839024152.00-22.15
CAediting_1384689chr19_52839008_-ENSG00000204604.8ENST00000243639hsa-miR-6813-3p52839006528390127mer-m85283900552839025140.00-10.68
CAediting_1384690chr19_52839009_-ENSG00000204604.8ENST00000243639hsa-miR-3192-5p52839008528390158mer-1a5283900852839031157.00-29.06
CAediting_1384690chr19_52839009_-ENSG00000204604.8ENST00000243639hsa-miR-32652839007528390137mer-m85283900652839025140.00-13.25
CAediting_1384690chr19_52839009_-ENSG00000204604.8ENST00000243639hsa-miR-330-5p52839007528390137mer-m85283900652839027140.00-19.59
CAediting_1384690chr19_52839009_-ENSG00000204604.8ENST00000243639hsa-miR-431452839008528390147mer-m85283900752839024150.00-21.39
CAediting_1384690chr19_52839009_-ENSG00000204604.8ENST00000243639hsa-miR-514a-5p52839006528390127mer-m85283900552839027150.00-19.05
CAediting_1384690chr19_52839009_-ENSG00000204604.8ENST00000243639hsa-miR-514a-5p52839006528390127mer-m85283900552839027150.00-19.05
CAediting_1384690chr19_52839009_-ENSG00000204604.8ENST00000243639hsa-miR-514a-5p52839006528390127mer-m85283900552839027150.00-19.05
CAediting_1384691chr19_52839010_-ENSG00000204604.8ENST00000243639hsa-miR-6771-5p52839008528390158mer-1a5283900852839031146.00-25.02
CAediting_1384692chr19_52839017_-ENSG00000204604.8ENST00000243639hsa-miR-25-5p52839015528390217mer-m85283901452839032148.00-24.69
CAediting_1384693chr19_52839027_-ENSG00000204604.8ENST00000243639hsa-miR-4750-5p52839022528390287mer-m85283902152839040153.00-22.18
CAediting_1384696chr19_52839063_-ENSG00000204604.8ENST00000243639hsa-miR-3190-5p52839057528390648mer-1a5283905752839075152.00-22.97
CAediting_1384696chr19_52839063_-ENSG00000204604.8ENST00000243639hsa-miR-548s52839059528390657mer-m85283905852839080149.00-13.14
CAediting_1384710chr19_52839344_-ENSG00000204604.8ENST00000243639hsa-miR-1180-5p52839339528393468mer-1a5283933952839359149.00-20.25
CAediting_1384710chr19_52839344_-ENSG00000204604.8ENST00000243639hsa-miR-1224-3p52839342528393487mer-m85283934152839361156.00-21.29
CAediting_1384710chr19_52839344_-ENSG00000204604.8ENST00000243639hsa-miR-7114-3p52839339528393468mer-1a5283933952839359155.00-23.80
CAediting_1384695chr19_52839059_-ENSG00000204604.8ENST00000243639hsa-miR-1180-3p52839056528390627mer-m85283905552839075161.00-24.78
CAediting_1384701chr19_52839114_-ENSG00000204604.8ENST00000243639hsa-miR-446652839110528391167mer-m85283910952839126140.00-23.04
CAediting_1384701chr19_52839114_-ENSG00000204604.8ENST00000243639hsa-miR-675-5p52839110528391167mer-m85283910952839128153.00-26.31
CAediting_1384702chr19_52839143_-ENSG00000204604.8ENST00000243639hsa-miR-6852-5p52839142528391476mer5283914152839160149.00-27.53
CAediting_1384704chr19_52839169_-ENSG00000204604.8ENST00000243639hsa-miR-453952839169528391746mer5283916852839190143.00-25.26
CAediting_1384707chr19_52839244_-ENSG00000204604.8ENST00000243639hsa-miR-3667-5p52839239528392457mer-m85283923852839261158.00-17.83
CAediting_1384709chr19_52839317_-ENSG00000204604.8ENST00000243639hsa-miR-6762-3p52839312528393187mer-m85283931152839338151.00-26.88
CAediting_1384712chr19_52839353_-ENSG00000204604.8ENST00000243639hsa-miR-5001-3p52839352528393587mer-m85283935152839370157.00-20.38
CAediting_1384712chr19_52839353_-ENSG00000204604.8ENST00000243639hsa-miR-593-3p52839348528393558mer-1a5283934852839366146.00-17.41
CAediting_1384712chr19_52839353_-ENSG00000204604.8ENST00000243639hsa-miR-6818-3p52839348528393547mer-m85283934752839367157.00-20.36
CAediting_1384714chr19_52839360_-ENSG00000204604.8ENST00000243639hsa-miR-150-5p52839357528393637mer-m85283935652839377140.00-15.80
CAediting_1384714chr19_52839360_-ENSG00000204604.8ENST00000243639hsa-miR-186-3p52839358528393658mer-1a5283935852839382149.00-17.80
CAediting_1384714chr19_52839360_-ENSG00000204604.8ENST00000243639hsa-miR-6778-3p52839354528393618mer-1a5283935452839374143.00-16.65
CAediting_1384715chr19_52839369_-ENSG00000204604.8ENST00000243639hsa-miR-371a-3p52839364528393707mer-m85283936352839385144.00-15.05
CAediting_1384717chr19_52839375_-ENSG00000204604.8ENST00000243639hsa-miR-513a-5p52839374528393807mer-m85283937352839390152.00-17.63
CAediting_1384717chr19_52839375_-ENSG00000204604.8ENST00000243639hsa-miR-513a-5p52839374528393807mer-m85283937352839390152.00-17.63
CAediting_1384718chr19_52841142_-ENSG00000204604.8ENST00000243639hsa-miR-216b-3p52841137528411448mer-1a5284113752841156149.00-14.79
CAediting_1384718chr19_52841142_-ENSG00000204604.8ENST00000243639hsa-miR-6500-3p52841140528411467mer-m85284113952841159151.00-15.63
CAediting_1384739chr19_52845228_-ENSG00000204604.8ENST00000602144hsa-miR-1247-3p52845226528452327mer-m85284522552845247164.00-27.61
CAediting_1384740chr19_52845257_-ENSG00000204604.8ENST00000602144hsa-miR-139-3p52845252528452587mer-m85284525152845274156.00-24.91
CAediting_1384740chr19_52845257_-ENSG00000204604.8ENST00000601980hsa-miR-139-3p52845252528452587mer-m85284525152845274156.00-24.91
CAediting_1384694chr19_52839057_-ENSG00000204604.8ENST00000243639hsa-miR-4793-5p52839054528390607mer-m85283905352839076154.00-20.69
CAediting_1384697chr19_52839071_-ENSG00000204604.8ENST00000243639hsa-miR-428552839068528390736mer5283906752839084140.00-21.12

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1384716chr19_52839374_-ENSG00000204604.8ENST00000243639hsa-miR-10399-5p52839373528393797mer-m85283937252839393144-12.53
CAediting_1384717chr19_52839375_-ENSG00000204604.8ENST00000243639hsa-miR-10399-5p52839373528393797mer-m85283937252839393144-12.53
CAediting_1384702chr19_52839143_-ENSG00000204604.8ENST00000243639hsa-miR-1212652839140528391478mer-1a5283914052839163147-16.86
CAediting_1384706chr19_52839208_-ENSG00000204604.8ENST00000243639hsa-miR-1227-3p52839207528392137mer-m85283920652839225148-21.83
CAediting_1384691chr19_52839010_-ENSG00000204604.8ENST00000243639hsa-miR-1273h-5p52839009528390168mer-1a5283900952839029153-16.96
CAediting_1384710chr19_52839344_-ENSG00000204604.8ENST00000243639hsa-miR-192-5p52839339528393457mer-m85283933852839358141-13.78
CAediting_1384710chr19_52839344_-ENSG00000204604.8ENST00000243639hsa-miR-215-5p52839339528393457mer-m85283933852839358141-11.61
CAediting_1384688chr19_52838999_-ENSG00000204604.8ENST00000243639hsa-miR-216a-5p52838996528390038mer-1a5283899652839017150-16.7
CAediting_1384703chr19_52839166_-ENSG00000204604.8ENST00000243639hsa-miR-219b-3p52839162528391687mer-m85283916152839181153-15.53
CAediting_1384718chr19_52841142_-ENSG00000204604.8ENST00000243639hsa-miR-23a-3p52841136528411438mer-1a5284113652841156155-15.18
CAediting_1384718chr19_52841142_-ENSG00000204604.8ENST00000243639hsa-miR-23b-3p52841136528411438mer-1a5284113652841158154-12.91
CAediting_1384718chr19_52841142_-ENSG00000204604.8ENST00000243639hsa-miR-23c52841136528411438mer-1a5284113652841157146-7.93
CAediting_1384709chr19_52839317_-ENSG00000204604.8ENST00000243639hsa-miR-26b-3p52839314528393207mer-m85283931352839333155-17.74
CAediting_1384703chr19_52839166_-ENSG00000204604.8ENST00000243639hsa-miR-302f52839163528391697mer-m85283916252839178147-8.32
CAediting_1384695chr19_52839059_-ENSG00000204604.8ENST00000243639hsa-miR-3064-5p52839057528390637mer-1a5283905752839077144-24.6
CAediting_1384696chr19_52839063_-ENSG00000204604.8ENST00000243639hsa-miR-3064-5p52839057528390637mer-1a5283905752839077144-24.6
CAediting_1384712chr19_52839353_-ENSG00000204604.8ENST00000243639hsa-miR-3152-5p52839352528393598mer-1a5283935252839373145-11.97
CAediting_1384713chr19_52839354_-ENSG00000204604.8ENST00000243639hsa-miR-3152-5p52839352528393598mer-1a5283935252839373145-11.97
CAediting_1384693chr19_52839027_-ENSG00000204604.8ENST00000243639hsa-miR-316552839025528390317mer-m85283902452839046148-12.38
CAediting_1384692chr19_52839017_-ENSG00000204604.8ENST00000243639hsa-miR-319852839017528390237mer-m85283901652839039155-27.54
CAediting_1384692chr19_52839017_-ENSG00000204604.8ENST00000243639hsa-miR-319852839017528390237mer-m85283901652839039155-27.54
CAediting_1384692chr19_52839017_-ENSG00000204604.8ENST00000243639hsa-miR-3689d52839012528390187mer-m85283901152839032145-18.55
CAediting_1384692chr19_52839017_-ENSG00000204604.8ENST00000243639hsa-miR-3689d52839012528390187mer-m85283901152839032145-18.55
CAediting_1384705chr19_52839190_-ENSG00000204604.8ENST00000243639hsa-miR-377-5p52839185528391917mer-m85283918452839207154-17.36
CAediting_1384700chr19_52839112_-ENSG00000204604.8ENST00000243639hsa-miR-3934-5p52839108528391147mer-m85283910752839128150-22.88
CAediting_1384709chr19_52839317_-ENSG00000204604.8ENST00000243639hsa-miR-427352839315528393217mer-m85283931452839331144-9.35
CAediting_1384692chr19_52839017_-ENSG00000204604.8ENST00000243639hsa-miR-430952839017528390237mer-m85283901652839035142-14.64
CAediting_1384711chr19_52839348_-ENSG00000204604.8ENST00000243639hsa-miR-442152839346528393527mer-m85283934552839366147-16.85
CAediting_1384707chr19_52839244_-ENSG00000204604.8ENST00000243639hsa-miR-443252839239528392457mer-m85283923852839260146-11.81
CAediting_1384698chr19_52839085_-ENSG00000204604.8ENST00000243639hsa-miR-4684-5p52839081528390877mer-m85283908052839102155-15.04
CAediting_1384709chr19_52839317_-ENSG00000204604.8ENST00000243639hsa-miR-4687-3p52839312528393187mer-m85283931152839331140-12.68
CAediting_1384695chr19_52839059_-ENSG00000204604.8ENST00000243639hsa-miR-479452839057528390648mer-1a5283905752839079151-22.13
CAediting_1384696chr19_52839063_-ENSG00000204604.8ENST00000243639hsa-miR-479452839057528390648mer-1a5283905752839079151-22.13
CAediting_1384715chr19_52839369_-ENSG00000204604.8ENST00000243639hsa-miR-512-3p52839364528393707mer-m85283936352839384149-15
CAediting_1384715chr19_52839369_-ENSG00000204604.8ENST00000243639hsa-miR-512-3p52839364528393707mer-m85283936352839384149-15
CAediting_1384714chr19_52839360_-ENSG00000204604.8ENST00000243639hsa-miR-513c-5p52839358528393636mer5283935752839378143-14.2
CAediting_1384705chr19_52839190_-ENSG00000204604.8ENST00000243639hsa-miR-608652839185528391917mer-m85283918452839203150-23.6
CAediting_1384692chr19_52839017_-ENSG00000204604.8ENST00000243639hsa-miR-613452839013528390197mer-m85283901252839032148-16.34
CAediting_1384705chr19_52839190_-ENSG00000204604.8ENST00000243639hsa-miR-6516-5p52839189528391957mer-m85283918852839207148-12.72
CAediting_1384695chr19_52839059_-ENSG00000204604.8ENST00000243639hsa-miR-664a-5p52839057528390648mer-1a5283905752839085142-17.57
CAediting_1384696chr19_52839063_-ENSG00000204604.8ENST00000243639hsa-miR-664a-5p52839057528390648mer-1a5283905752839085142-17.57
CAediting_1384693chr19_52839027_-ENSG00000204604.8ENST00000243639hsa-miR-6756-5p52839024528390296mer5283902352839045141-21.95
CAediting_1384691chr19_52839010_-ENSG00000204604.8ENST00000243639hsa-miR-6779-5p52839009528390168mer-1a5283900952839027148-23.94
CAediting_1384692chr19_52839017_-ENSG00000204604.8ENST00000243639hsa-miR-6851-5p52839012528390187mer-m85283901152839032155-23.8
CAediting_1384717chr19_52839375_-ENSG00000204604.8ENST00000243639hsa-miR-7151-3p52839374528393818mer-1a5283937452839397150-24.32
CAediting_1384702chr19_52839143_-ENSG00000204604.8ENST00000243639hsa-miR-887-5p52839143528391497mer-m85283914252839161143-20.14
CAediting_1384690chr19_52839009_-ENSG00000204604.8ENST00000243639hsa-miR-887-5p52839008528390158mer-1a5283900852839028140-10.85
CAediting_1384691chr19_52839010_-ENSG00000204604.8ENST00000243639hsa-miR-887-5p52839008528390158mer-1a5283900852839028140-10.85
CAediting_1384739chr19_52845228_-ENSG00000204604.8ENST00000602144hsa-miR-204-3p52845227528452337mer-m85284522652845246145-19.74
CAediting_1384739chr19_52845228_-ENSG00000204604.8ENST00000602144hsa-miR-3192-5p52845227528452326mer5284522652845251152-28.88
CAediting_1384740chr19_52845257_-ENSG00000204604.8ENST00000602144hsa-miR-425-5p52845256528452627mer-m85284525552845277143-12.18
CAediting_1384740chr19_52845257_-ENSG00000204604.8ENST00000602144hsa-miR-608852845253528452597mer-m85284525252845271143-12.77
CAediting_1384740chr19_52845257_-ENSG00000204604.8ENST00000601980hsa-miR-425-5p52845256528452627mer-m85284525552845277143-12.18
CAediting_1384740chr19_52845257_-ENSG00000204604.8ENST00000601980hsa-miR-608852845253528452597mer-m85284525252845271143-12.77

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_980496chr14_31014685_-ENSG00000204604.8ENST00000243639hsa-miR-624-3p52840678528406858mer-1a5284067852840701147-13.23
CAediting_1160181chr17_7017644_-ENSG00000204604.8ENST00000243639hsa-miR-195-3p52839447528394548mer-1a5283944752839468144-11.36
CAediting_86358chr1_109598906_+ENSG00000204604.8ENST00000243639hsa-miR-197-5p52839024528390307mer-m85283902352839045153-27.47
CAediting_414656chr5_72878640_+ENSG00000204604.8ENST00000243639hsa-miR-4804-3p52839751528397577mer-m85283975052839776144-22.06
CAediting_524911chr7_5495852_-ENSG00000204604.8ENST00000243639hsa-miR-589-3p52839233528392397mer-m85283923252839256158-19.59

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1229413chr17_67471544_+ENSG00000204604.8ENST00000243639hsa-miR-548aa52840261528402677mer-m85284026052840288155-12.43
CAediting_1229414chr17_67471546_+ENSG00000204604.8ENST00000243639hsa-miR-548aa52840261528402677mer-m85284026052840288155-12.43
CAediting_1229415chr17_67471547_+ENSG00000204604.8ENST00000243639hsa-miR-548aa52840261528402677mer-m85284026052840288155-12.43
CAediting_980496chr14_31014685_-ENSG00000204604.8ENST00000243639hsa-miR-624-3p52840339528403468mer-1a5284033952840360154-11.6
CAediting_980496chr14_31014685_-ENSG00000204604.8ENST00000243639hsa-miR-624-3p52840311528403188mer-1a5284031152840332154-12.94

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ZNF468

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for ZNF468

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
BLCACAediting_1384689chr19_52839008_-2.16075689165993e-090.399959443076756....
LGGCAediting_1384689chr19_52839008_-0.01471828530906330.301328593610144....
BRCACAediting_1384689chr19_52839008_-8.30515418462479e-640.540660630449973....
LIHCCAediting_1384689chr19_52839008_-1.21459492912514e-050.270185059680811....
CESCCAediting_1384689chr19_52839008_-1.72981072392024e-060.349564626585049....
LUADCAediting_1384689chr19_52839008_-4.8463981899608e-290.5072650765214....
COADCAediting_1384689chr19_52839008_-2.21949997213382e-050.317332434792744....
LUSCCAediting_1384689chr19_52839008_-2.31628301397734e-060.295327044786025....
PRADCAediting_1384689chr19_52839008_-6.2677874188111e-190.471909859808385....
HNSCCAediting_1384689chr19_52839008_-9.15526402606242e-050.253980082046532....
STADCAediting_1384689chr19_52839008_-1.96177120578037e-070.331522085643316....
THCACAediting_1384689chr19_52839008_-9.27400941577515e-080.300902479352545....
KIRCCAediting_1384689chr19_52839008_-1.35880010909897e-080.264239137897994....
UCECCAediting_1384689chr19_52839008_-6.75416343414077e-120.383233727263922....
KIRPCAediting_1384689chr19_52839008_-8.47993872840739e-060.394028372252566....
ESCACAediting_1384689chr19_52839008_-0.0001190340333182360.361864781228965....
OVCAediting_1384689chr19_52839008_-8.56774871875118e-080.333938870029339....
PAADCAediting_1384689chr19_52839008_-3.9594140413633e-070.42288615838148....
SKCMCAediting_1384689chr19_52839008_-0.0009318414975061540.294829742483761....
READCAediting_1384689chr19_52839008_-0.03162447700817620.30137368090565....
SARCCAediting_1384689chr19_52839008_-0.002702872769669740.294038732153665....
TGCTCAediting_1384689chr19_52839008_-7.31831373566132e-070.473742686785898....
BLCACAediting_1384690chr19_52839009_-0.001529131535648730.334745723988404....
BRCACAediting_1384690chr19_52839009_-3.08617521020922e-260.469697846332876....
LIHCCAediting_1384690chr19_52839009_-0.001075023360359050.234238057847682....
CESCCAediting_1384690chr19_52839009_-0.0002315124763041460.391436941278647....
LUADCAediting_1384690chr19_52839009_-2.34012607321321e-150.492864626865852....
PRADCAediting_1384690chr19_52839009_-0.005866126319704090.370172936971975....
HNSCCAediting_1384690chr19_52839009_-0.04813026487086690.190632069476746....
STADCAediting_1384690chr19_52839009_-9.63585139870873e-050.337802998411558....
KIRCCAediting_1384690chr19_52839009_-0.000487821776265840.253901794904333....
UCECCAediting_1384690chr19_52839009_-0.0002086976525637560.362675942096222....
OVCAediting_1384690chr19_52839009_-0.0005389497117805530.287806570121997....
PAADCAediting_1384690chr19_52839009_-0.001281391651702970.402995923383267....
TGCTCAediting_1384690chr19_52839009_-0.002111598258599130.409405339002267....
BRCACAediting_1384692chr19_52839017_-3.69325587444481e-100.46081292660416....
LIHCCAediting_1384692chr19_52839017_-....0.04613566142667360.198913729248115
LUADCAediting_1384692chr19_52839017_-0.001591325651339470.314841806004396....
OVCAediting_1384692chr19_52839017_-0.03143399542878470.271392688924513....
BLCACAediting_1384696chr19_52839063_-9.76332982057137e-100.432444412127506....
BRCACAediting_1384696chr19_52839063_-2.12819009136599e-270.424603951984587....
LIHCCAediting_1384696chr19_52839063_-0.002947605490518610.224134654864814....
CESCCAediting_1384696chr19_52839063_-....0.04649208304617730.208132162941095
LUADCAediting_1384696chr19_52839063_-9.17357417533117e-170.467387482663664....
LUSCCAediting_1384696chr19_52839063_-1.5266265043367e-050.342922689084995....
PRADCAediting_1384696chr19_52839063_-6.77394112990246e-060.379162908700326..0.03051662408308420.187684919586839
STADCAediting_1384696chr19_52839063_-5.1625430562669e-050.307921851017982....
THCACAediting_1384696chr19_52839063_-8.62518628593768e-050.302620288575192....
KIRCCAediting_1384696chr19_52839063_-0.001358099634217710.200343084063407....
UCECCAediting_1384696chr19_52839063_-3.20253565433303e-100.443561397009155....
OVCAediting_1384696chr19_52839063_-0.0007227939757295570.235967442363033....
PAADCAediting_1384696chr19_52839063_-0.0007732622480871440.359865402324243....
SKCMCAediting_1384696chr19_52839063_-0.002963386912557020.33643572824513....
SARCCAediting_1384696chr19_52839063_-0.0002045415007499620.426973718009556....
TGCTCAediting_1384696chr19_52839063_-0.0005348094640199340.417778003741286....
BLCACAediting_1384710chr19_52839344_-6.28631092238886e-090.430638628544246....
BRCACAediting_1384710chr19_52839344_-7.97028490782993e-360.467678494879619....
LIHCCAediting_1384710chr19_52839344_-0.001452654152452440.243753175022084....
CESCCAediting_1384710chr19_52839344_-....0.008050364031962210.287314826803332
LUADCAediting_1384710chr19_52839344_-1.84334018220512e-140.415615524743881....
LUSCCAediting_1384710chr19_52839344_-1.25929759057036e-060.372179656902157....
PRADCAediting_1384710chr19_52839344_-1.7900338570022e-060.376150085631878....
STADCAediting_1384710chr19_52839344_-0.002175344871002960.247602853462316....
THCACAediting_1384710chr19_52839344_-0.007092316714720930.200600824777621....
UCECCAediting_1384710chr19_52839344_-0.006353483575333510.224882740601581....
ESCACAediting_1384710chr19_52839344_-..0.008874802466043220.322127792910528..
OVCAediting_1384710chr19_52839344_-0.0005224705296026450.235718356007821....
PAADCAediting_1384710chr19_52839344_-0.001088730721211410.352321251010475....
SARCCAediting_1384710chr19_52839344_-0.002274758087260250.340649810826022....
TGCTCAediting_1384710chr19_52839344_-1.95294689164732e-050.525139040492215....

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Relation with cancer stages for ZNF468

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
BRCApathologic_stageCAediting_1384689chr19_52839008_-0.01617588440102490.0844797382369891
BRCApathologic_stageCAediting_1384690chr19_52839009_-0.03701726892308730.0992366489233174
HNSCclinical_stageCAediting_1384710chr19_52839344_-0.005637256620467970.264678968354971
KIRCpathologic_stageCAediting_1384689chr19_52839008_-0.0002121926149142380.174339760989837
KIRCpathologic_stageCAediting_1384710chr19_52839344_-0.00702049163626680.166821440421033
KIRPclinical_stageCAediting_1384710chr19_52839344_-0.0370388766255935-0.339506451636874
KIRPpathologic_stageCAediting_1384689chr19_52839008_-0.007994353715176610.251678374335039
LIHCpathologic_stageCAediting_1384689chr19_52839008_-0.0186343010850605-0.152098765002153
PAADpathologic_stageCAediting_1384690chr19_52839009_-0.04493690353722050.257721956031912
THCApathologic_stageCAediting_1384696chr19_52839063_-0.04122389883942080.160578573523174

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Relation with survival for ZNF468

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR
LUADCAediting_1384689chr19_52839008_-0.02193376497954120.006741174.68446

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RelatedDrugs for ZNF468

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ZNF468

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource