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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: KLC4 (CAeditome ID:89953)

Gene summary for KLC4

check button Gene summary
Gene informationGene symbol

KLC4

Gene ID

89953

Gene namekinesin light chain 4
SynonymsKNSL8|bA387M24.3
Cytomap

6p21.1

Type of geneprotein-coding
Descriptionkinesin light chain 4kinesin-like protein 8
Modification date20210518
UniProtAcc

Q9NSK0

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for KLC4

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000137171.13

check button RNA A-to-I editing events in Cancer.
CAediting_483719(43062374, +), CAediting_483720(43063657, +), CAediting_483721(43063737, +), CAediting_483722(43064020, +), CAediting_483723(43064059, +), CAediting_483724(43064342, +), CAediting_483725(43064364, +), CAediting_483726(43064365, +), CAediting_483727(43064366, +), CAediting_483728(43064449, +), CAediting_483729(43064459, +), CAediting_483730(43064465, +), CAediting_483731(43064469, +), CAediting_483732(43064479, +), CAediting_483733(43067492, +), CAediting_483734(43067528, +), CAediting_483735(43067545, +), CAediting_483736(43067578, +), CAediting_483737(43067583, +), CAediting_483738(43067607, +), CAediting_483739(43067615, +), CAediting_483740(43067616, +), CAediting_483741(43067632, +), CAediting_483742(43067637, +), CAediting_483743(43067645, +), CAediting_483744(43067674, +), CAediting_483745(43067701, +), CAediting_483746(43067707, +), CAediting_483747(43067716, +), CAediting_483748(43067736, +), CAediting_483749(43067765, +), CAediting_483750(43067997, +), CAediting_483751(43068024, +), CAediting_483752(43068032, +), CAediting_483753(43068218, +), CAediting_483754(43068262, +), CAediting_483755(43068271, +), CAediting_483756(43068295, +), CAediting_483757(43068296, +), CAediting_483758(43068307, +), CAediting_483759(43068310, +), CAediting_483760(43068311, +), CAediting_483761(43068312, +), CAediting_483762(43068314, +), CAediting_483763(43068319, +), CAediting_483764(43068321, +), CAediting_483765(43068325, +), CAediting_483766(43068351, +), CAediting_483767(43068352, +), CAediting_483768(43068357, +), CAediting_483769(43068361, +), CAediting_483770(43068365, +), CAediting_483771(43068383, +), CAediting_483772(43068392, +), CAediting_483773(43068393, +), CAediting_483774(43068397, +), CAediting_483775(43068460, +), CAediting_483776(43068463, +), CAediting_483777(43068575, +), CAediting_483778(43068585, +), CAediting_483779(43068588, +), CAediting_483780(43068598, +), CAediting_483781(43068607, +), CAediting_483782(43068621, +), CAediting_483783(43068665, +), CAediting_483784(43068669, +), CAediting_483785(43068673, +), CAediting_483786(43068691, +), CAediting_483787(43068692, +), CAediting_483788(43068698, +), CAediting_483789(43068701, +), CAediting_483790(43068709, +), CAediting_483791(43068756, +), CAediting_483792(43068768, +), CAediting_483793(43068798, +), CAediting_483794(43068888, +), CAediting_483795(43068922, +), CAediting_483796(43068946, +), CAediting_483797(43068949, +), CAediting_483798(43068950, +), CAediting_483799(43068952, +), CAediting_483800(43068957, +), CAediting_483801(43068961, +), CAediting_483802(43068987, +), CAediting_483803(43069029, +), CAediting_483804(43069033, +), CAediting_483805(43069079, +), CAediting_483806(43069293, +), CAediting_483807(43069306, +), CAediting_483808(43069308, +), CAediting_483809(43069319, +), CAediting_483810(43069338, +), CAediting_483811(43069344, +), CAediting_483812(43069362, +), CAediting_483813(43069374, +), CAediting_483814(43069384, +), CAediting_483815(43069386, +), CAediting_483816(43069390, +), CAediting_483817(43069410, +), CAediting_483818(43069425, +), CAediting_483819(43069428, +), CAediting_483820(43069492, +), CAediting_483821(43069506, +), CAediting_483822(43069507, +), CAediting_483823(43069537, +), CAediting_483824(43069572, +), CAediting_483825(43069580, +), CAediting_483826(43069597, +), CAediting_483827(43069612, +), CAediting_483828(43069650, +), CAediting_483829(43069654, +), CAediting_483830(43069655, +), CAediting_483831(43069668, +), CAediting_483832(43069680, +), CAediting_483833(43069690, +), CAediting_483834(43069714, +), CAediting_483835(43069722, +), CAediting_483836(43069728, +), CAediting_483837(43069731, +), CAediting_483838(43069782, +), CAediting_483839(43069787, +), CAediting_483840(43069810, +), CAediting_483841(43069844, +), CAediting_483842(43073553, +),

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RNA editing positional annotations for KLC4 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_483719chr6_43062374_+intronic
CAediting_483720chr6_43063657_+ncRNA_intronic
CAediting_483721chr6_43063737_+ncRNA_intronic
CAediting_483722chr6_43064020_+ncRNA_intronic
CAediting_483723chr6_43064059_+ncRNA_intronic
CAediting_483724chr6_43064342_+ncRNA_intronic
CAediting_483725chr6_43064364_+ncRNA_intronic
CAediting_483726chr6_43064365_+ncRNA_intronic
CAediting_483727chr6_43064366_+ncRNA_intronic
CAediting_483728chr6_43064449_+ncRNA_intronic
CAediting_483729chr6_43064459_+ncRNA_intronic
CAediting_483730chr6_43064465_+ncRNA_intronic
CAediting_483731chr6_43064469_+ncRNA_intronic
CAediting_483732chr6_43064479_+ncRNA_intronic
CAediting_483733chr6_43067492_+intronic
CAediting_483734chr6_43067528_+intronic
CAediting_483735chr6_43067545_+intronic
CAediting_483736chr6_43067578_+intronic
CAediting_483737chr6_43067583_+intronic
CAediting_483738chr6_43067607_+intronic
CAediting_483739chr6_43067615_+intronic
CAediting_483740chr6_43067616_+intronic
CAediting_483741chr6_43067632_+intronic
CAediting_483742chr6_43067637_+intronic
CAediting_483743chr6_43067645_+intronic
CAediting_483744chr6_43067674_+intronic
CAediting_483745chr6_43067701_+intronic
CAediting_483746chr6_43067707_+intronic
CAediting_483747chr6_43067716_+intronic
CAediting_483748chr6_43067736_+intronic
CAediting_483749chr6_43067765_+intronic
CAediting_483750chr6_43067997_+intronic
CAediting_483751chr6_43068024_+intronic
CAediting_483752chr6_43068032_+intronic
CAediting_483753chr6_43068218_+intronic
CAediting_483754chr6_43068262_+intronic
CAediting_483755chr6_43068271_+intronic
CAediting_483756chr6_43068295_+intronic
CAediting_483757chr6_43068296_+intronic
CAediting_483758chr6_43068307_+intronic
CAediting_483759chr6_43068310_+intronic
CAediting_483760chr6_43068311_+intronic
CAediting_483761chr6_43068312_+intronic
CAediting_483762chr6_43068314_+intronic
CAediting_483763chr6_43068319_+intronic
CAediting_483764chr6_43068321_+intronic
CAediting_483765chr6_43068325_+intronic
CAediting_483766chr6_43068351_+intronic
CAediting_483767chr6_43068352_+intronic
CAediting_483768chr6_43068357_+intronic
CAediting_483769chr6_43068361_+intronic
CAediting_483770chr6_43068365_+intronic
CAediting_483771chr6_43068383_+intronic
CAediting_483772chr6_43068392_+intronic
CAediting_483773chr6_43068393_+intronic
CAediting_483774chr6_43068397_+intronic
CAediting_483775chr6_43068460_+intronic
CAediting_483776chr6_43068463_+intronic
CAediting_483777chr6_43068575_+intronic
CAediting_483778chr6_43068585_+intronic
CAediting_483779chr6_43068588_+intronic
CAediting_483780chr6_43068598_+intronic
CAediting_483781chr6_43068607_+intronic
CAediting_483782chr6_43068621_+intronic
CAediting_483783chr6_43068665_+intronic
CAediting_483784chr6_43068669_+intronic
CAediting_483785chr6_43068673_+intronic
CAediting_483786chr6_43068691_+intronic
CAediting_483787chr6_43068692_+intronic
CAediting_483788chr6_43068698_+intronic
CAediting_483789chr6_43068701_+intronic
CAediting_483790chr6_43068709_+intronic
CAediting_483791chr6_43068756_+intronic
CAediting_483792chr6_43068768_+intronic
CAediting_483793chr6_43068798_+intronic
CAediting_483794chr6_43068888_+intronic
CAediting_483795chr6_43068922_+intronic
CAediting_483796chr6_43068946_+intronic
CAediting_483797chr6_43068949_+intronic
CAediting_483798chr6_43068950_+intronic
CAediting_483799chr6_43068952_+intronic
CAediting_483800chr6_43068957_+intronic
CAediting_483801chr6_43068961_+intronic
CAediting_483802chr6_43068987_+intronic
CAediting_483803chr6_43069029_+intronic
CAediting_483804chr6_43069033_+intronic
CAediting_483805chr6_43069079_+intronic
CAediting_483806chr6_43069293_+intronic
CAediting_483807chr6_43069306_+intronic
CAediting_483808chr6_43069308_+intronic
CAediting_483809chr6_43069319_+intronic
CAediting_483810chr6_43069338_+intronic
CAediting_483811chr6_43069344_+intronic
CAediting_483812chr6_43069362_+intronic
CAediting_483813chr6_43069374_+intronic
CAediting_483814chr6_43069384_+intronic
CAediting_483815chr6_43069386_+intronic
CAediting_483816chr6_43069390_+intronic
CAediting_483817chr6_43069410_+intronic
CAediting_483818chr6_43069425_+intronic
CAediting_483819chr6_43069428_+intronic
CAediting_483820chr6_43069492_+intronic
CAediting_483821chr6_43069506_+intronic
CAediting_483822chr6_43069507_+intronic
CAediting_483823chr6_43069537_+intronic
CAediting_483824chr6_43069572_+intronic
CAediting_483825chr6_43069580_+intronic
CAediting_483826chr6_43069597_+intronic
CAediting_483827chr6_43069612_+intronic
CAediting_483828chr6_43069650_+intronic
CAediting_483829chr6_43069654_+intronic
CAediting_483830chr6_43069655_+intronic
CAediting_483831chr6_43069668_+intronic
CAediting_483832chr6_43069680_+intronic
CAediting_483833chr6_43069690_+intronic
CAediting_483834chr6_43069714_+intronic
CAediting_483835chr6_43069722_+intronic
CAediting_483836chr6_43069728_+intronic
CAediting_483837chr6_43069731_+intronic
CAediting_483838chr6_43069782_+intronic
CAediting_483839chr6_43069787_+intronic
CAediting_483840chr6_43069810_+intronic
CAediting_483841chr6_43069844_+intronic
CAediting_483842chr6_43073553_+ncRNA_exonic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_483719chr6_43062374_+SINEAluAluSx3
CAediting_483720chr6_43063657_+SINEAluAluSq2
CAediting_483721chr6_43063737_+SINEAluAluSq2
CAediting_483722chr6_43064020_+SINEAluAluSz6
CAediting_483723chr6_43064059_+SINEAluAluSz6
CAediting_483724chr6_43064342_+SINEAluAluJr
CAediting_483725chr6_43064364_+SINEAluAluJr
CAediting_483726chr6_43064365_+SINEAluAluJr
CAediting_483727chr6_43064366_+SINEAluAluJr
CAediting_483728chr6_43064449_+SINEAluAluJr
CAediting_483729chr6_43064459_+SINEAluAluJr
CAediting_483730chr6_43064465_+SINEAluAluJr
CAediting_483731chr6_43064469_+SINEAluAluJr
CAediting_483732chr6_43064479_+SINEAluAluJr
CAediting_483734chr6_43067528_+SINEAluAluY
CAediting_483735chr6_43067545_+SINEAluAluY
CAediting_483736chr6_43067578_+SINEAluAluY
CAediting_483737chr6_43067583_+SINEAluAluY
CAediting_483738chr6_43067607_+SINEAluAluY
CAediting_483739chr6_43067615_+SINEAluAluY
CAediting_483740chr6_43067616_+SINEAluAluY
CAediting_483741chr6_43067632_+SINEAluAluY
CAediting_483742chr6_43067637_+SINEAluAluY
CAediting_483743chr6_43067645_+SINEAluAluY
CAediting_483744chr6_43067674_+SINEAluAluY
CAediting_483745chr6_43067701_+SINEAluAluY
CAediting_483746chr6_43067707_+SINEAluAluY
CAediting_483747chr6_43067716_+SINEAluAluY
CAediting_483748chr6_43067736_+SINEAluAluY
CAediting_483749chr6_43067765_+SINEAluAluY
CAediting_483750chr6_43067997_+SINEAluAluYa5
CAediting_483751chr6_43068024_+SINEAluAluYa5
CAediting_483752chr6_43068032_+SINEAluAluYa5
CAediting_483753chr6_43068218_+SINEAluAluSq4
CAediting_483754chr6_43068262_+SINEAluAluSq4
CAediting_483755chr6_43068271_+SINEAluAluSq4
CAediting_483756chr6_43068295_+SINEAluAluSq4
CAediting_483757chr6_43068296_+SINEAluAluSq4
CAediting_483758chr6_43068307_+SINEAluAluSq4
CAediting_483759chr6_43068310_+SINEAluAluSq4
CAediting_483760chr6_43068311_+SINEAluAluSq4
CAediting_483761chr6_43068312_+SINEAluAluSq4
CAediting_483762chr6_43068314_+SINEAluAluSq4
CAediting_483763chr6_43068319_+SINEAluAluSq4
CAediting_483764chr6_43068321_+SINEAluAluSq4
CAediting_483765chr6_43068325_+SINEAluAluSq4
CAediting_483766chr6_43068351_+SINEAluAluSq4
CAediting_483767chr6_43068352_+SINEAluAluSq4
CAediting_483768chr6_43068357_+SINEAluAluSq4
CAediting_483769chr6_43068361_+SINEAluAluSq4
CAediting_483770chr6_43068365_+SINEAluAluSq4
CAediting_483771chr6_43068383_+SINEAluAluSq4
CAediting_483772chr6_43068392_+SINEAluAluSq4
CAediting_483773chr6_43068393_+SINEAluAluSq4
CAediting_483774chr6_43068397_+SINEAluAluSq4
CAediting_483775chr6_43068460_+SINEAluAluSq4
CAediting_483776chr6_43068463_+SINEAluAluSq4
CAediting_483777chr6_43068575_+SINEAluAluSx
CAediting_483778chr6_43068585_+SINEAluAluSx
CAediting_483779chr6_43068588_+SINEAluAluSx
CAediting_483780chr6_43068598_+SINEAluAluSx
CAediting_483781chr6_43068607_+SINEAluAluSx
CAediting_483782chr6_43068621_+SINEAluAluSx
CAediting_483783chr6_43068665_+SINEAluAluSx
CAediting_483784chr6_43068669_+SINEAluAluSx
CAediting_483785chr6_43068673_+SINEAluAluSx
CAediting_483786chr6_43068691_+SINEAluAluSx
CAediting_483787chr6_43068692_+SINEAluAluSx
CAediting_483788chr6_43068698_+SINEAluAluSx
CAediting_483789chr6_43068701_+SINEAluAluSx
CAediting_483790chr6_43068709_+SINEAluAluSx
CAediting_483791chr6_43068756_+SINEAluAluSx
CAediting_483792chr6_43068768_+SINEAluAluSx
CAediting_483793chr6_43068798_+SINEAluAluSx
CAediting_483794chr6_43068888_+SINEAluAluSx
CAediting_483795chr6_43068922_+SINEAluAluSx
CAediting_483796chr6_43068946_+SINEAluAluSx
CAediting_483797chr6_43068949_+SINEAluAluSx
CAediting_483798chr6_43068950_+SINEAluAluSx
CAediting_483799chr6_43068952_+SINEAluAluSx
CAediting_483800chr6_43068957_+SINEAluAluSx
CAediting_483801chr6_43068961_+SINEAluAluSx
CAediting_483802chr6_43068987_+SINEAluAluSx
CAediting_483803chr6_43069029_+SINEAluAluSx
CAediting_483804chr6_43069033_+SINEAluAluSx
CAediting_483805chr6_43069079_+SINEAluAluSx
CAediting_483806chr6_43069293_+SINEAluAluSz
CAediting_483807chr6_43069306_+SINEAluAluSz
CAediting_483808chr6_43069308_+SINEAluAluSz
CAediting_483809chr6_43069319_+SINEAluAluSz
CAediting_483810chr6_43069338_+SINEAluAluSz
CAediting_483811chr6_43069344_+SINEAluAluSz
CAediting_483812chr6_43069362_+SINEAluAluSz
CAediting_483813chr6_43069374_+SINEAluAluSz
CAediting_483814chr6_43069384_+SINEAluAluSz
CAediting_483815chr6_43069386_+SINEAluAluSz
CAediting_483816chr6_43069390_+SINEAluAluSz
CAediting_483817chr6_43069410_+SINEAluAluSz
CAediting_483818chr6_43069425_+SINEAluAluSz
CAediting_483819chr6_43069428_+SINEAluAluSz
CAediting_483820chr6_43069492_+SINEAluAluSz
CAediting_483821chr6_43069506_+SINEAluAluSz
CAediting_483822chr6_43069507_+SINEAluAluSz
CAediting_483823chr6_43069537_+SINEAluAluSz
CAediting_483824chr6_43069572_+SINEAluAluSp
CAediting_483825chr6_43069580_+SINEAluAluSp
CAediting_483826chr6_43069597_+SINEAluAluSp
CAediting_483827chr6_43069612_+SINEAluAluSp
CAediting_483828chr6_43069650_+SINEAluAluSp
CAediting_483829chr6_43069654_+SINEAluAluSp
CAediting_483830chr6_43069655_+SINEAluAluSp
CAediting_483831chr6_43069668_+SINEAluAluSp
CAediting_483832chr6_43069680_+SINEAluAluSp
CAediting_483833chr6_43069690_+SINEAluAluSp
CAediting_483834chr6_43069714_+SINEAluAluSp
CAediting_483835chr6_43069722_+SINEAluAluSp
CAediting_483836chr6_43069728_+SINEAluAluSp
CAediting_483837chr6_43069731_+SINEAluAluSp
CAediting_483838chr6_43069782_+SINEAluAluSp
CAediting_483839chr6_43069787_+SINEAluAluSp
CAediting_483840chr6_43069810_+SINEAluAluSp
CAediting_483841chr6_43069844_+SINEAluAluSp
CAediting_483842chr6_43073553_+SINEAluAluSq2

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RNA A-to-I editing events in the alternative splicing sites for KLC4

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000137171.13.KLC4.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000137171.13.KLC4.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for KLC4

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for KLC4

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for KLC4

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_846604chr11_93733708_-ENSG00000137171.13ENST00000467906hsa-miR-1304-3p43070790430707967mer-m84307077543070797151-19.56
CAediting_980496chr14_31014685_-ENSG00000137171.13ENST00000467906hsa-miR-624-3p43074874430748807mer-m84307486143074881143-16.15
CAediting_393chr1_1167164_+ENSG00000137171.13ENST00000467906hsa-miR-200b-3p43074724430747307mer-m84307471043074731141-12.17
CAediting_980496chr14_31014685_-ENSG00000137171.13ENST00000453940hsa-miR-624-3p43074874430748807mer-m84307486143074881143-16.15
CAediting_393chr1_1167164_+ENSG00000137171.13ENST00000453940hsa-miR-200b-3p43074724430747307mer-m84307471043074731141-12.17
CAediting_748296chr10_51299626_+ENSG00000137171.13ENST00000458460hsa-miR-605-3p43067166430671727mer-1a4306715243067172146-15.76
CAediting_980496chr14_31014685_-ENSG00000137171.13ENST00000259708hsa-miR-624-3p43074874430748807mer-m84307486143074881143-16.15
CAediting_393chr1_1167164_+ENSG00000137171.13ENST00000259708hsa-miR-200b-3p43074724430747307mer-m84307471043074731141-12.17
CAediting_980496chr14_31014685_-ENSG00000137171.13ENST00000479388hsa-miR-624-3p43074874430748807mer-m84307486143074881143-16.15
CAediting_393chr1_1167164_+ENSG00000137171.13ENST00000479388hsa-miR-200b-3p43074724430747307mer-m84307471043074731141-12.17
CAediting_980496chr14_31014685_-ENSG00000137171.13ENST00000394056hsa-miR-624-3p43074874430748807mer-m84307486143074881143-16.15
CAediting_393chr1_1167164_+ENSG00000137171.13ENST00000394056hsa-miR-200b-3p43074724430747307mer-m84307471043074731141-12.17
CAediting_77128chr1_85133844_+ENSG00000137171.13ENST00000467906hsa-miR-4423-3p43071341430713477mer-m84307132843071348140-14.63
CAediting_1054808chr15_66496985_-ENSG00000137171.13ENST00000467906hsa-miR-451243074905430749128mer-1a4307489243074912153-20.9
CAediting_1229415chr17_67471547_+ENSG00000137171.13ENST00000467906hsa-miR-548aa43074959430749657mer-m84307494343074966148-14.66
CAediting_1054808chr15_66496985_-ENSG00000137171.13ENST00000259708hsa-miR-451243074905430749128mer-1a4307489243074912153-20.9
CAediting_1229415chr17_67471547_+ENSG00000137171.13ENST00000259708hsa-miR-548aa43074959430749657mer-m84307494343074966148-14.66
CAediting_1054808chr15_66496985_-ENSG00000137171.13ENST00000479388hsa-miR-451243074905430749128mer-1a4307489243074912153-20.9
CAediting_1229415chr17_67471547_+ENSG00000137171.13ENST00000479388hsa-miR-548aa43074959430749657mer-m84307494343074966148-14.66
CAediting_524911chr7_5495852_-ENSG00000137171.13ENST00000481499hsa-miR-589-3p43060559430605657mer-m84306053943060566141-18.28
CAediting_524911chr7_5495852_-ENSG00000137171.13ENST00000481499hsa-miR-589-3p43060591430605977mer-m84306057343060598157-18.3
CAediting_1160181chr17_7017644_-ENSG00000137171.13ENST00000481499hsa-miR-195-3p43061563430615708mer-1a4306154943061570147-10.58
CAediting_1054808chr15_66496985_-ENSG00000137171.13ENST00000394056hsa-miR-451243074905430749128mer-1a4307489243074912153-20.9
CAediting_1229415chr17_67471547_+ENSG00000137171.13ENST00000394056hsa-miR-548aa43074959430749657mer-m84307494343074966148-14.66

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1524209chrX_134546392_-ENSG00000137171.13ENST00000467906hsa-miR-503-5p43074954430749596mer4307493743074960147-27.9
CAediting_1524209chrX_134546392_-ENSG00000137171.13ENST00000259708hsa-miR-503-5p43074954430749596mer4307493743074960147-27.9
CAediting_1524209chrX_134546392_-ENSG00000137171.13ENST00000479388hsa-miR-503-5p43074954430749596mer4307493743074960147-27.9
CAediting_1054808chr15_66496985_-ENSG00000137171.13ENST00000481499hsa-miR-451243061435430614428mer-1a4306142043061442146-20.83
CAediting_1524209chrX_134546392_-ENSG00000137171.13ENST00000394056hsa-miR-503-5p43074954430749596mer4307493743074960147-27.9

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for KLC4

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000463168.1retained_intronSoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_483842ENST00000463168.1chr6_43073553_+-206.20-207.00-206.20

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Relation with ADAR for KLC4

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for KLC4

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for KLC4

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for KLC4

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for KLC4

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
KLC4C0037772Spastic Paraplegia1GENOMICS_ENGLAND