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Editing gene: HERC2 (CAeditome ID:8924)

Gene summary for HERC2

Gene summary

Gene information	Gene symbol	HERC2
	Gene ID	8924
	Gene name	HECT and RLD domain containing E3 ubiquitin protein ligase 2
	Synonyms	D15F37S1\|MRT38\|SHEP1\|jdf2\|p528
	Cytomap	15q13.1
	Type of gene	protein-coding
	Description	E3 ubiquitin-protein ligase HERC2HECT-type E3 ubiquitin transferase HERC2hect domain and RCC1-like domain-containing protein 2hect domain and RLD 2probable E3 ubiquitin-protein ligase HERC2
	Modification date	20210531
	UniProtAcc	O95714
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
HERC2	GO:0032183	E3 ubiquitin-protein ligase HERC2	22508508
HERC2	GO:0061630	E3 ubiquitin-protein ligase HERC2	20304803
HERC2	GO:0006974	E3 ubiquitin-protein ligase HERC2	22508508
HERC2	GO:0016567	E3 ubiquitin-protein ligase HERC2	20304803
HERC2	GO:0005634	E3 ubiquitin-protein ligase HERC2	20304803
HERC2	GO:0005737	E3 ubiquitin-protein ligase HERC2	20304803
HERC2	GO:0005829	E3 ubiquitin-protein ligase HERC2	0000052
HERC2	GO:0005886	E3 ubiquitin-protein ligase HERC2	0000052

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RNA A-to-I events for HERC2

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000128731.14

RNA A-to-I editing events in Cancer.

CAediting_1025023(28119033, -), CAediting_1025024(28119278, -), CAediting_1025025(28119314, -), CAediting_1025026(28119551, -), CAediting_1025027(28119627, -), CAediting_1025028(28119633, -), CAediting_1025029(28119672, -), CAediting_1025030(28176470, -), CAediting_1025031(28183245, -), CAediting_1025032(28183272, -), CAediting_1025033(28183281, -), CAediting_1025034(28183472, -), CAediting_1025035(28188830, -), CAediting_1025036(28188956, -), CAediting_1025037(28188964, -), CAediting_1025038(28189005, -), CAediting_1025039(28189036, -), CAediting_1025040(28190105, -), CAediting_1025041(28190137, -), CAediting_1025042(28190141, -), CAediting_1025043(28190153, -), CAediting_1025044(28190253, -), CAediting_1025045(28190256, -), CAediting_1025046(28190292, -), CAediting_1025047(28206925, -), CAediting_1025048(28210064, -), CAediting_1025049(28210272, -), CAediting_1025050(28210304, -), CAediting_1025051(28249758, -), CAediting_1025052(28254207, -), CAediting_1025053(28257940, -), CAediting_1025054(28258350, -), CAediting_1025055(28258453, -), CAediting_1025056(28259129, -), CAediting_1025057(28259376, -), CAediting_1025058(28279103, -), CAediting_1025059(28287791, -), CAediting_1025060(28287796, -), CAediting_1025061(28287844, -), CAediting_1025062(28287852, -), CAediting_1025063(28287862, -), CAediting_1025064(28287896, -), CAediting_1025065(28287899, -), CAediting_1025066(28287903, -), CAediting_1025067(28287904, -), CAediting_1025068(28287905, -), CAediting_1025069(28287942, -), CAediting_1025070(28287953, -), CAediting_1025071(28287991, -), CAediting_1025072(28293250, -), CAediting_1025073(28304397, -), CAediting_1025074(28304398, -), CAediting_1025075(28304457, -), CAediting_1025076(28304465, -), CAediting_1025077(28304470, -), CAediting_1025078(28304479, -), CAediting_1025079(28304496, -), CAediting_1025080(28304532, -), CAediting_1025081(28304535, -), CAediting_1025082(28304536, -), CAediting_1025083(28304538, -), CAediting_1025084(28304539, -), CAediting_1025085(28304541, -), CAediting_1025086(28304543, -), CAediting_1025087(28304544, -), CAediting_1025088(28304545, -), CAediting_1025089(28304546, -), CAediting_1025090(28304547, -), CAediting_1025091(28304569, -), CAediting_1025092(28304571, -), CAediting_1025093(28304572, -), CAediting_1025094(28304609, -), CAediting_1025095(28304637, -), CAediting_1025096(28304643, -), CAediting_1025097(28313342, -), CAediting_1025098(28313384, -), CAediting_1025099(28313385, -), CAediting_1025100(28315638, -), CAediting_1025101(28316422, -), CAediting_1025102(28316438, -), CAediting_1025103(28316472, -), CAediting_1025104(28316849, -), CAediting_1025105(28316869, -), CAediting_1025106(28316925, -), CAediting_1025107(28316970, -), CAediting_1025108(28320142, -), CAediting_1025109(28320143, -), CAediting_1025110(28320144, -), CAediting_1025111(28320162, -), CAediting_1025112(28320211, -), CAediting_1025113(28320226, -), CAediting_1025114(28320243, -), CAediting_1025115(28320247, -), CAediting_1025116(28320252, -), CAediting_1025117(28320253, -), CAediting_1025118(28320307, -), CAediting_1025119(28320317, -), CAediting_1025120(28320386, -),

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RNA editing positional annotations for HERC2 using Annovar

Protein coding RNA editing(s).

CAeditome ID	Position	Variant type	ENST	NTchange	AAchange	SIFT_score	Polyphen2_HVAR_score	PROVEAN_pred
CAediting_1025030	chr15_28176470_-	nonsynonymous SNV	ENST00000261609.10	c.A9644G	p.Q3215R	T	D	D

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1025023	chr15_28119033_-	intronic
CAediting_1025024	chr15_28119278_-	intronic
CAediting_1025025	chr15_28119314_-	intronic
CAediting_1025026	chr15_28119551_-	intronic
CAediting_1025027	chr15_28119627_-	intronic
CAediting_1025028	chr15_28119633_-	intronic
CAediting_1025029	chr15_28119672_-	intronic
CAediting_1025030	chr15_28176470_-	exonic
CAediting_1025031	chr15_28183245_-	intronic
CAediting_1025032	chr15_28183272_-	intronic
CAediting_1025033	chr15_28183281_-	intronic
CAediting_1025034	chr15_28183472_-	intronic
CAediting_1025035	chr15_28188830_-	intronic
CAediting_1025036	chr15_28188956_-	intronic
CAediting_1025037	chr15_28188964_-	intronic
CAediting_1025038	chr15_28189005_-	intronic
CAediting_1025039	chr15_28189036_-	intronic
CAediting_1025040	chr15_28190105_-	intronic
CAediting_1025041	chr15_28190137_-	intronic
CAediting_1025042	chr15_28190141_-	intronic
CAediting_1025043	chr15_28190153_-	intronic
CAediting_1025044	chr15_28190253_-	ncRNA_exonic
CAediting_1025045	chr15_28190256_-	ncRNA_exonic
CAediting_1025046	chr15_28190292_-	ncRNA_exonic
CAediting_1025047	chr15_28206925_-	intronic
CAediting_1025048	chr15_28210064_-	intronic
CAediting_1025049	chr15_28210272_-	intronic
CAediting_1025050	chr15_28210304_-	intronic
CAediting_1025051	chr15_28249758_-	intronic
CAediting_1025052	chr15_28254207_-	intronic
CAediting_1025053	chr15_28257940_-	intronic
CAediting_1025054	chr15_28258350_-	intronic
CAediting_1025055	chr15_28258453_-	intronic
CAediting_1025056	chr15_28259129_-	intronic
CAediting_1025057	chr15_28259376_-	intronic
CAediting_1025058	chr15_28279103_-	intronic
CAediting_1025059	chr15_28287791_-	ncRNA_intronic
CAediting_1025060	chr15_28287796_-	ncRNA_intronic
CAediting_1025061	chr15_28287844_-	ncRNA_intronic
CAediting_1025062	chr15_28287852_-	ncRNA_intronic
CAediting_1025063	chr15_28287862_-	ncRNA_intronic
CAediting_1025064	chr15_28287896_-	ncRNA_intronic
CAediting_1025065	chr15_28287899_-	ncRNA_intronic
CAediting_1025066	chr15_28287903_-	ncRNA_intronic
CAediting_1025067	chr15_28287904_-	ncRNA_intronic
CAediting_1025068	chr15_28287905_-	ncRNA_intronic
CAediting_1025069	chr15_28287942_-	ncRNA_intronic
CAediting_1025070	chr15_28287953_-	ncRNA_intronic
CAediting_1025071	chr15_28287991_-	ncRNA_intronic
CAediting_1025072	chr15_28293250_-	ncRNA_intronic
CAediting_1025073	chr15_28304397_-	intronic
CAediting_1025074	chr15_28304398_-	intronic
CAediting_1025075	chr15_28304457_-	intronic
CAediting_1025076	chr15_28304465_-	intronic
CAediting_1025077	chr15_28304470_-	intronic
CAediting_1025078	chr15_28304479_-	intronic
CAediting_1025079	chr15_28304496_-	intronic
CAediting_1025080	chr15_28304532_-	intronic
CAediting_1025081	chr15_28304535_-	intronic
CAediting_1025082	chr15_28304536_-	intronic
CAediting_1025083	chr15_28304538_-	intronic
CAediting_1025084	chr15_28304539_-	intronic
CAediting_1025085	chr15_28304541_-	intronic
CAediting_1025086	chr15_28304543_-	intronic
CAediting_1025087	chr15_28304544_-	intronic
CAediting_1025088	chr15_28304545_-	intronic
CAediting_1025089	chr15_28304546_-	intronic
CAediting_1025090	chr15_28304547_-	intronic
CAediting_1025091	chr15_28304569_-	intronic
CAediting_1025092	chr15_28304571_-	intronic
CAediting_1025093	chr15_28304572_-	intronic
CAediting_1025094	chr15_28304609_-	intronic
CAediting_1025095	chr15_28304637_-	intronic
CAediting_1025096	chr15_28304643_-	intronic
CAediting_1025097	chr15_28313342_-	intronic
CAediting_1025098	chr15_28313384_-	intronic
CAediting_1025099	chr15_28313385_-	intronic
CAediting_1025100	chr15_28315638_-	intronic
CAediting_1025101	chr15_28316422_-	intronic
CAediting_1025102	chr15_28316438_-	intronic
CAediting_1025103	chr15_28316472_-	intronic
CAediting_1025104	chr15_28316849_-	intronic
CAediting_1025105	chr15_28316869_-	intronic
CAediting_1025106	chr15_28316925_-	intronic
CAediting_1025107	chr15_28316970_-	intronic
CAediting_1025108	chr15_28320142_-	ncRNA_exonic
CAediting_1025109	chr15_28320143_-	ncRNA_exonic
CAediting_1025110	chr15_28320144_-	ncRNA_exonic
CAediting_1025111	chr15_28320162_-	ncRNA_exonic
CAediting_1025112	chr15_28320211_-	ncRNA_exonic
CAediting_1025113	chr15_28320226_-	ncRNA_exonic
CAediting_1025114	chr15_28320243_-	ncRNA_exonic
CAediting_1025115	chr15_28320247_-	ncRNA_exonic
CAediting_1025116	chr15_28320252_-	ncRNA_exonic
CAediting_1025117	chr15_28320253_-	ncRNA_exonic
CAediting_1025118	chr15_28320307_-	ncRNA_exonic
CAediting_1025119	chr15_28320317_-	ncRNA_exonic
CAediting_1025120	chr15_28320386_-	ncRNA_exonic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1025023	chr15_28119033_-	SINE	Alu	AluSx
CAediting_1025024	chr15_28119278_-	SINE	Alu	AluSx
CAediting_1025025	chr15_28119314_-	SINE	Alu	AluSx
CAediting_1025026	chr15_28119551_-	SINE	Alu	AluJb
CAediting_1025027	chr15_28119627_-	SINE	Alu	AluJb
CAediting_1025028	chr15_28119633_-	SINE	Alu	AluJb
CAediting_1025029	chr15_28119672_-	SINE	Alu	AluJb
CAediting_1025031	chr15_28183245_-	SINE	Alu	AluJb
CAediting_1025032	chr15_28183272_-	SINE	Alu	AluJb
CAediting_1025033	chr15_28183281_-	SINE	Alu	AluJb
CAediting_1025034	chr15_28183472_-	SINE	Alu	AluJb
CAediting_1025035	chr15_28188830_-	SINE	Alu	AluSx1
CAediting_1025036	chr15_28188956_-	SINE	Alu	AluSx1
CAediting_1025037	chr15_28188964_-	SINE	Alu	AluSx1
CAediting_1025038	chr15_28189005_-	SINE	Alu	AluSx1
CAediting_1025039	chr15_28189036_-	SINE	Alu	AluSx1
CAediting_1025040	chr15_28190105_-	SINE	Alu	AluY
CAediting_1025041	chr15_28190137_-	SINE	Alu	AluY
CAediting_1025042	chr15_28190141_-	SINE	Alu	AluY
CAediting_1025043	chr15_28190153_-	SINE	Alu	AluY
CAediting_1025044	chr15_28190253_-	SINE	Alu	AluY
CAediting_1025045	chr15_28190256_-	SINE	Alu	AluY
CAediting_1025046	chr15_28190292_-	SINE	Alu	AluY
CAediting_1025047	chr15_28206925_-	SINE	Alu	AluSc5
CAediting_1025048	chr15_28210064_-	SINE	Alu	AluSx1
CAediting_1025049	chr15_28210272_-	SINE	Alu	AluY
CAediting_1025050	chr15_28210304_-	SINE	Alu	AluY
CAediting_1025051	chr15_28249758_-	SINE	Alu	AluSc5
CAediting_1025052	chr15_28254207_-	SINE	Alu	AluSp
CAediting_1025053	chr15_28257940_-	SINE	Alu	AluY
CAediting_1025054	chr15_28258350_-	SINE	Alu	AluSp
CAediting_1025055	chr15_28258453_-	SINE	Alu	AluSp
CAediting_1025056	chr15_28259129_-	SINE	Alu	AluSq2
CAediting_1025057	chr15_28259376_-	SINE	Alu	AluSq2
CAediting_1025058	chr15_28279103_-	SINE	Alu	AluSp
CAediting_1025059	chr15_28287791_-	SINE	Alu	AluY
CAediting_1025060	chr15_28287796_-	SINE	Alu	AluY
CAediting_1025061	chr15_28287844_-	SINE	Alu	AluY
CAediting_1025062	chr15_28287852_-	SINE	Alu	AluY
CAediting_1025063	chr15_28287862_-	SINE	Alu	AluY
CAediting_1025064	chr15_28287896_-	SINE	Alu	AluY
CAediting_1025065	chr15_28287899_-	SINE	Alu	AluY
CAediting_1025066	chr15_28287903_-	SINE	Alu	AluY
CAediting_1025067	chr15_28287904_-	SINE	Alu	AluY
CAediting_1025068	chr15_28287905_-	SINE	Alu	AluY
CAediting_1025069	chr15_28287942_-	SINE	Alu	AluY
CAediting_1025070	chr15_28287953_-	SINE	Alu	AluY
CAediting_1025071	chr15_28287991_-	SINE	Alu	AluY
CAediting_1025072	chr15_28293250_-	SINE	Alu	AluY
CAediting_1025073	chr15_28304397_-	SINE	Alu	AluSx1
CAediting_1025074	chr15_28304398_-	SINE	Alu	AluSx1
CAediting_1025075	chr15_28304457_-	SINE	Alu	AluSx1
CAediting_1025076	chr15_28304465_-	SINE	Alu	AluSx1
CAediting_1025077	chr15_28304470_-	SINE	Alu	AluSx1
CAediting_1025078	chr15_28304479_-	SINE	Alu	AluSx1
CAediting_1025079	chr15_28304496_-	SINE	Alu	AluSx1
CAediting_1025080	chr15_28304532_-	SINE	Alu	AluSx1
CAediting_1025081	chr15_28304535_-	SINE	Alu	AluSx1
CAediting_1025082	chr15_28304536_-	SINE	Alu	AluSx1
CAediting_1025083	chr15_28304538_-	SINE	Alu	AluSx1
CAediting_1025084	chr15_28304539_-	SINE	Alu	AluSx1
CAediting_1025085	chr15_28304541_-	SINE	Alu	AluSx1
CAediting_1025086	chr15_28304543_-	SINE	Alu	AluSx1
CAediting_1025087	chr15_28304544_-	SINE	Alu	AluSx1
CAediting_1025088	chr15_28304545_-	SINE	Alu	AluSx1
CAediting_1025089	chr15_28304546_-	SINE	Alu	AluSx1
CAediting_1025090	chr15_28304547_-	SINE	Alu	AluSx1
CAediting_1025091	chr15_28304569_-	SINE	Alu	AluSx1
CAediting_1025092	chr15_28304571_-	SINE	Alu	AluSx1
CAediting_1025093	chr15_28304572_-	SINE	Alu	AluSx1
CAediting_1025094	chr15_28304609_-	SINE	Alu	AluSx1
CAediting_1025095	chr15_28304637_-	SINE	Alu	AluSx1
CAediting_1025096	chr15_28304643_-	SINE	Alu	AluSx1
CAediting_1025097	chr15_28313342_-	SINE	Alu	AluY
CAediting_1025098	chr15_28313384_-	SINE	Alu	AluY
CAediting_1025099	chr15_28313385_-	SINE	Alu	AluY
CAediting_1025100	chr15_28315638_-	SINE	Alu	AluSx
CAediting_1025101	chr15_28316422_-	SINE	Alu	AluJo
CAediting_1025102	chr15_28316438_-	SINE	Alu	AluJo
CAediting_1025103	chr15_28316472_-	SINE	Alu	AluJo
CAediting_1025104	chr15_28316849_-	SINE	Alu	AluSc
CAediting_1025105	chr15_28316869_-	SINE	Alu	AluSc
CAediting_1025106	chr15_28316925_-	SINE	Alu	AluSc
CAediting_1025107	chr15_28316970_-	SINE	Alu	AluSc
CAediting_1025108	chr15_28320142_-	SINE	Alu	AluSq2
CAediting_1025109	chr15_28320143_-	SINE	Alu	AluSq2
CAediting_1025110	chr15_28320144_-	SINE	Alu	AluSq2
CAediting_1025111	chr15_28320162_-	SINE	Alu	AluSq2
CAediting_1025112	chr15_28320211_-	SINE	Alu	AluSq2
CAediting_1025113	chr15_28320226_-	SINE	Alu	AluSq2
CAediting_1025114	chr15_28320243_-	SINE	Alu	AluSq2
CAediting_1025115	chr15_28320247_-	SINE	Alu	AluSq2
CAediting_1025116	chr15_28320252_-	SINE	Alu	AluSq2
CAediting_1025117	chr15_28320253_-	SINE	Alu	AluSq2
CAediting_1025118	chr15_28320307_-	SINE	Alu	AluSq2
CAediting_1025119	chr15_28320317_-	SINE	Alu	AluSq2
CAediting_1025120	chr15_28320386_-	SINE	Alu	AluSq2

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RNA A-to-I editing events in the alternative splicing sites for HERC2

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000128731.14.HERC2.

Correlation between RNA A-to-I editing and PSI for ENSG00000128731.14.HERC2.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for HERC2

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for HERC2

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for HERC2

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_846604	chr11_93733708_-	ENSG00000128731.14	ENST00000564734	hsa-miR-1304-3p	28260906	28260912	7mer-m8	28260905	28260924	153	-23.3
CAediting_393	chr1_1167164_+	ENSG00000128731.14	ENST00000564734	hsa-miR-200b-3p	28260829	28260835	7mer-m8	28260828	28260848	152	-18.19
CAediting_1160181	chr17_7017644_-	ENSG00000128731.14	ENST00000564734	hsa-miR-195-3p	28268577	28268583	7mer-m8	28268576	28268596	143	-12.71
CAediting_228905	chr2_188297554_+	ENSG00000128731.14	ENST00000564734	hsa-miR-561-3p	28262933	28262939	7mer-m8	28262932	28262952	150	-12.07
CAediting_86358	chr1_109598906_+	ENSG00000128731.14	ENST00000564734	hsa-miR-197-5p	28260934	28260941	8mer-1a	28260934	28260956	157	-26.23

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_573001	chr7_92204086_-	ENSG00000128731.14	ENST00000261609	hsa-miR-1285-5p	28111739	28111745	7mer-m8	28111738	28111761	145	-18.91

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for HERC2

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for HERC2

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for HERC2

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for HERC2

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for HERC2

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for HERC2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
HERC2	C3809753	MENTAL RETARDATION, AUTOSOMAL RECESSIVE 38	2	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HERC2	C0009324	Ulcerative Colitis	1	CTD_human
HERC2	C0264423	Asthma, Occupational	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene