Home

Download

Statistics

Examples

Help

Contact

Editing gene: ARHGEF7 (CAeditome ID:8874)

Gene summary for ARHGEF7

Gene summary

Gene information	Gene symbol	ARHGEF7
	Gene ID	8874
	Gene name	Rho guanine nucleotide exchange factor 7
	Synonyms	BETA-PIX\|COOL-1\|COOL1\|Nbla10314\|P50\|P50BP\|P85\|P85COOL1\|P85SPR\|PAK3\|PIXB
	Cytomap	13q34
	Type of gene	protein-coding
	Description	rho guanine nucleotide exchange factor 7PAK-interacting exchange factor betaRho guanine nucleotide exchange factor (GEF) 7SH3 domain-containing proline-rich protein
	Modification date	20210518
	UniProtAcc	Q14155
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
ARHGEF7	GO:0005085	Rho guanine nucleotide exchange factor 7	21048939
ARHGEF7	GO:0043015	Rho guanine nucleotide exchange factor 7	27012601
ARHGEF7	GO:0043547	Rho guanine nucleotide exchange factor 7	21048939
ARHGEF7	GO:0005813	Rho guanine nucleotide exchange factor 7	27012601
ARHGEF7	GO:0043005	Rho guanine nucleotide exchange factor 7	21048939
ARHGEF7	GO:0043025	Rho guanine nucleotide exchange factor 7	21048939
ARHGEF7	GO:0097431	Rho guanine nucleotide exchange factor 7	27012601
ARHGEF7	GO:0032991	Rho guanine nucleotide exchange factor 7	11864573

Top

RNA A-to-I events for ARHGEF7

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000102606.16

RNA A-to-I editing events in Cancer.

CAediting_973397(111160576, +), CAediting_973398(111169288, +), CAediting_973399(111169294, +), CAediting_973400(111184268, +), CAediting_973401(111206706, +), CAediting_973402(111206707, +), CAediting_973403(111206712, +), CAediting_973404(111206723, +), CAediting_973405(111206750, +), CAediting_973406(111206759, +), CAediting_973407(111206761, +), CAediting_973408(111206774, +), CAediting_973409(111206776, +), CAediting_973410(111206815, +), CAediting_973411(111206841, +), CAediting_973412(111206847, +), CAediting_973413(111206851, +), CAediting_973414(111206868, +), CAediting_973415(111206882, +), CAediting_973416(111206883, +), CAediting_973417(111206927, +), CAediting_973418(111207184, +), CAediting_973419(111207220, +), CAediting_973420(111207222, +), CAediting_973421(111207233, +), CAediting_973422(111207238, +), CAediting_973423(111207243, +), CAediting_973424(111207247, +), CAediting_973425(111207248, +), CAediting_973426(111207268, +), CAediting_973427(111207272, +), CAediting_973428(111207281, +), CAediting_973429(111207298, +), CAediting_973430(111207310, +), CAediting_973431(111207334, +), CAediting_973432(111207335, +), CAediting_973433(111207351, +), CAediting_973434(111207388, +), CAediting_973435(111207389, +), CAediting_973436(111207397, +), CAediting_973437(111207442, +), CAediting_973438(111208102, +), CAediting_973439(111208136, +), CAediting_973440(111208140, +), CAediting_973441(111208167, +), CAediting_973442(111208170, +), CAediting_973443(111208180, +), CAediting_973444(111208184, +), CAediting_973445(111208186, +), CAediting_973446(111208308, +), CAediting_973447(111220898, +), CAediting_973448(111221687, +), CAediting_973449(111221727, +), CAediting_973450(111221731, +), CAediting_973451(111221732, +), CAediting_973452(111221734, +), CAediting_973453(111221748, +), CAediting_973454(111265003, +),

Top

RNA editing positional annotations for ARHGEF7 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_973397	chr13_111160576_+	intronic
CAediting_973398	chr13_111169288_+	intronic
CAediting_973399	chr13_111169294_+	intronic
CAediting_973400	chr13_111184268_+	intronic
CAediting_973401	chr13_111206706_+	intronic
CAediting_973402	chr13_111206707_+	intronic
CAediting_973403	chr13_111206712_+	intronic
CAediting_973404	chr13_111206723_+	intronic
CAediting_973405	chr13_111206750_+	intronic
CAediting_973406	chr13_111206759_+	intronic
CAediting_973407	chr13_111206761_+	intronic
CAediting_973408	chr13_111206774_+	intronic
CAediting_973409	chr13_111206776_+	intronic
CAediting_973410	chr13_111206815_+	intronic
CAediting_973411	chr13_111206841_+	intronic
CAediting_973412	chr13_111206847_+	intronic
CAediting_973413	chr13_111206851_+	intronic
CAediting_973414	chr13_111206868_+	intronic
CAediting_973415	chr13_111206882_+	intronic
CAediting_973416	chr13_111206883_+	intronic
CAediting_973417	chr13_111206927_+	intronic
CAediting_973418	chr13_111207184_+	intronic
CAediting_973419	chr13_111207220_+	intronic
CAediting_973420	chr13_111207222_+	intronic
CAediting_973421	chr13_111207233_+	intronic
CAediting_973422	chr13_111207238_+	intronic
CAediting_973423	chr13_111207243_+	intronic
CAediting_973424	chr13_111207247_+	intronic
CAediting_973425	chr13_111207248_+	intronic
CAediting_973426	chr13_111207268_+	intronic
CAediting_973427	chr13_111207272_+	intronic
CAediting_973428	chr13_111207281_+	intronic
CAediting_973429	chr13_111207298_+	intronic
CAediting_973430	chr13_111207310_+	intronic
CAediting_973431	chr13_111207334_+	intronic
CAediting_973432	chr13_111207335_+	intronic
CAediting_973433	chr13_111207351_+	intronic
CAediting_973434	chr13_111207388_+	intronic
CAediting_973435	chr13_111207389_+	intronic
CAediting_973436	chr13_111207397_+	intronic
CAediting_973437	chr13_111207442_+	intronic
CAediting_973438	chr13_111208102_+	intronic
CAediting_973439	chr13_111208136_+	intronic
CAediting_973440	chr13_111208140_+	intronic
CAediting_973441	chr13_111208167_+	intronic
CAediting_973442	chr13_111208170_+	intronic
CAediting_973443	chr13_111208180_+	intronic
CAediting_973444	chr13_111208184_+	intronic
CAediting_973445	chr13_111208186_+	intronic
CAediting_973446	chr13_111208308_+	intronic
CAediting_973447	chr13_111220898_+	intronic
CAediting_973448	chr13_111221687_+	intronic
CAediting_973449	chr13_111221727_+	intronic
CAediting_973450	chr13_111221731_+	intronic
CAediting_973451	chr13_111221732_+	intronic
CAediting_973452	chr13_111221734_+	intronic
CAediting_973453	chr13_111221748_+	intronic
CAediting_973454	chr13_111265003_+	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_973397	chr13_111160576_+	LTR	ERVL-MaLR	THE1D
CAediting_973398	chr13_111169288_+	LTR	ERVL-MaLR	MSTA
CAediting_973399	chr13_111169294_+	LTR	ERVL-MaLR	MSTA
CAediting_973400	chr13_111184268_+	LTR	ERVL-MaLR	THE1C
CAediting_973401	chr13_111206706_+	SINE	Alu	AluY
CAediting_973402	chr13_111206707_+	SINE	Alu	AluY
CAediting_973403	chr13_111206712_+	SINE	Alu	AluY
CAediting_973404	chr13_111206723_+	SINE	Alu	AluY
CAediting_973405	chr13_111206750_+	SINE	Alu	AluY
CAediting_973406	chr13_111206759_+	SINE	Alu	AluY
CAediting_973407	chr13_111206761_+	SINE	Alu	AluY
CAediting_973408	chr13_111206774_+	SINE	Alu	AluY
CAediting_973409	chr13_111206776_+	SINE	Alu	AluY
CAediting_973410	chr13_111206815_+	SINE	Alu	AluY
CAediting_973411	chr13_111206841_+	SINE	Alu	AluY
CAediting_973412	chr13_111206847_+	SINE	Alu	AluY
CAediting_973413	chr13_111206851_+	SINE	Alu	AluY
CAediting_973414	chr13_111206868_+	SINE	Alu	AluY
CAediting_973415	chr13_111206882_+	SINE	Alu	AluY
CAediting_973416	chr13_111206883_+	SINE	Alu	AluY
CAediting_973417	chr13_111206927_+	SINE	Alu	AluY
CAediting_973418	chr13_111207184_+	SINE	Alu	AluJo
CAediting_973419	chr13_111207220_+	SINE	Alu	AluJo
CAediting_973420	chr13_111207222_+	SINE	Alu	AluJo
CAediting_973421	chr13_111207233_+	SINE	Alu	AluJo
CAediting_973422	chr13_111207238_+	SINE	Alu	AluJo
CAediting_973423	chr13_111207243_+	SINE	Alu	AluJo
CAediting_973424	chr13_111207247_+	SINE	Alu	AluJo
CAediting_973425	chr13_111207248_+	SINE	Alu	AluJo
CAediting_973426	chr13_111207268_+	SINE	Alu	AluJo
CAediting_973427	chr13_111207272_+	SINE	Alu	AluJo
CAediting_973428	chr13_111207281_+	SINE	Alu	AluJo
CAediting_973429	chr13_111207298_+	SINE	Alu	AluJo
CAediting_973430	chr13_111207310_+	SINE	Alu	AluJo
CAediting_973431	chr13_111207334_+	SINE	Alu	AluJo
CAediting_973432	chr13_111207335_+	SINE	Alu	AluJo
CAediting_973433	chr13_111207351_+	SINE	Alu	AluJo
CAediting_973434	chr13_111207388_+	SINE	Alu	AluJo
CAediting_973435	chr13_111207389_+	SINE	Alu	AluJo
CAediting_973436	chr13_111207397_+	SINE	Alu	AluJo
CAediting_973437	chr13_111207442_+	SINE	Alu	AluJo
CAediting_973438	chr13_111208102_+	SINE	Alu	AluSp
CAediting_973439	chr13_111208136_+	SINE	Alu	AluSp
CAediting_973440	chr13_111208140_+	SINE	Alu	AluSp
CAediting_973441	chr13_111208167_+	SINE	Alu	AluSp
CAediting_973442	chr13_111208170_+	SINE	Alu	AluSp
CAediting_973443	chr13_111208180_+	SINE	Alu	AluSp
CAediting_973444	chr13_111208184_+	SINE	Alu	AluSp
CAediting_973445	chr13_111208186_+	SINE	Alu	AluSp
CAediting_973446	chr13_111208308_+	SINE	Alu	AluSp
CAediting_973448	chr13_111221687_+	Simple_repeat	Simple_repeat	(AT)n
CAediting_973454	chr13_111265003_+	SINE	Alu	AluSp

Top

RNA A-to-I editing events in the alternative splicing sites for ARHGEF7

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000102606.16.ARHGEF7.

Correlation between RNA A-to-I editing and PSI for ENSG00000102606.16.ARHGEF7.

Top

Differntial gene expression between RNA A-to-I edited versus non-edited samples for ARHGEF7

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Top

Protein coding region RNA A-to-I editings for ARHGEF7

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

Top

The effects of the RNA editing to the miRNA binding sites for ARHGEF7

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_980496	chr14_31014685_-	ENSG00000102606.16	ENST00000469877	hsa-miR-624-3p	111267608	111267615	8mer-1a	111267595	111267615	152	-12.11
CAediting_393	chr1_1167164_+	ENSG00000102606.16	ENST00000218789	hsa-miR-200b-3p	111303717	111303724	8mer-1a	111303706	111303724	150	-13.53
CAediting_688080	chr9_63819626_+	ENSG00000102606.16	ENST00000218789	hsa-miR-4477b	111304801	111304807	7mer-m8	111304787	111304808	159	-10.69
CAediting_393	chr1_1167164_+	ENSG00000102606.16	ENST00000375736	hsa-miR-200b-3p	111303717	111303724	8mer-1a	111303706	111303724	150	-13.53
CAediting_688080	chr9_63819626_+	ENSG00000102606.16	ENST00000375736	hsa-miR-4477b	111304801	111304807	7mer-m8	111304787	111304808	159	-10.69
CAediting_393	chr1_1167164_+	ENSG00000102606.16	ENST00000426073	hsa-miR-200b-3p	111303717	111303724	8mer-1a	111303706	111303724	150	-13.53
CAediting_688080	chr9_63819626_+	ENSG00000102606.16	ENST00000426073	hsa-miR-4477b	111304801	111304807	7mer-m8	111304787	111304808	159	-10.69
CAediting_1160181	chr17_7017644_-	ENSG00000102606.16	ENST00000375739	hsa-miR-195-3p	111294083	111294090	8mer-1a	111294069	111294090	140	-8.74
CAediting_1160181	chr17_7017644_-	ENSG00000102606.16	ENST00000375741	hsa-miR-195-3p	111294083	111294090	8mer-1a	111294069	111294090	140	-8.74
CAediting_228905	chr2_188297554_+	ENSG00000102606.16	ENST00000469877	hsa-miR-561-3p	111266867	111266873	7mer-m8	111266853	111266874	144	-15.54
CAediting_228905	chr2_188297554_+	ENSG00000102606.16	ENST00000469877	hsa-miR-561-3p	111275619	111275625	7mer-m8	111275604	111275626	153	-14.22
CAediting_1229415	chr17_67471547_+	ENSG00000102606.16	ENST00000469877	hsa-miR-548aa	111277657	111277664	8mer-1a	111277642	111277664	156	-13.03
CAediting_604450	chr7_133034877_-	ENSG00000102606.16	ENST00000469877	hsa-miR-3654	111283161	111283168	8mer-1a	111283150	111283168	147	-16.34
CAediting_1229413	chr17_67471544_+	ENSG00000102606.16	ENST00000218789	hsa-miR-548aa	111304394	111304400	7mer-m8	111304377	111304401	150	-11.86
CAediting_77128	chr1_85133844_+	ENSG00000102606.16	ENST00000218789	hsa-miR-4423-3p	111304677	111304683	7mer-m8	111304664	111304684	154	-17.64
CAediting_396018	chr5_1062918_-	ENSG00000102606.16	ENST00000218789	hsa-miR-4635	111303783	111303789	7mer-m8	111303770	111303790	163	-22.61
CAediting_1229413	chr17_67471544_+	ENSG00000102606.16	ENST00000375736	hsa-miR-548aa	111304394	111304400	7mer-m8	111304377	111304401	150	-11.86
CAediting_77128	chr1_85133844_+	ENSG00000102606.16	ENST00000375736	hsa-miR-4423-3p	111304677	111304683	7mer-m8	111304664	111304684	154	-17.64
CAediting_396018	chr5_1062918_-	ENSG00000102606.16	ENST00000375736	hsa-miR-4635	111303783	111303789	7mer-m8	111303770	111303790	163	-22.61
CAediting_1229413	chr17_67471544_+	ENSG00000102606.16	ENST00000426073	hsa-miR-548aa	111304394	111304400	7mer-m8	111304377	111304401	150	-11.86
CAediting_77128	chr1_85133844_+	ENSG00000102606.16	ENST00000426073	hsa-miR-4423-3p	111304677	111304683	7mer-m8	111304664	111304684	154	-17.64
CAediting_396018	chr5_1062918_-	ENSG00000102606.16	ENST00000426073	hsa-miR-4635	111303783	111303789	7mer-m8	111303770	111303790	163	-22.61
CAediting_1160181	chr17_7017644_-	ENSG00000102606.16	ENST00000375723	hsa-miR-195-3p	111294083	111294090	8mer-1a	111294069	111294090	140	-8.74
CAediting_1524209	chrX_134546392_-	ENSG00000102606.16	ENST00000469877	hsa-miR-503-5p	111283214	111283220	7mer-m8	111283199	111283221	142	-15.15
CAediting_468389	chr6_31355314_-	ENSG00000102606.16	ENST00000218789	hsa-miR-6891-5p	111304094	111304099	6mer	111304078	111304100	148	-30
CAediting_468389	chr6_31355314_-	ENSG00000102606.16	ENST00000375736	hsa-miR-6891-5p	111304094	111304099	6mer	111304078	111304100	148	-30
CAediting_468389	chr6_31355314_-	ENSG00000102606.16	ENST00000426073	hsa-miR-6891-5p	111304094	111304099	6mer	111304078	111304100	148	-30
CAediting_468389	chr6_31355314_-	ENSG00000102606.16	ENST00000544132	hsa-miR-6891-5p	111280891	111280898	8mer-1a	111280878	111280898	144	-25.98

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1229415	chr17_67471547_+	ENSG00000102606.16	ENST00000317133	hsa-miR-548aa	111292601	111292607	7mer-m8	111292584	111292608	140	-7.46
CAediting_524911	chr7_5495852_-	ENSG00000102606.16	ENST00000317133	hsa-miR-589-3p	111292846	111292852	7mer-m8	111292831	111292853	155	-20.83
CAediting_393	chr1_1167164_+	ENSG00000102606.16	ENST00000375739	hsa-miR-200b-3p	111294781	111294786	6mer	111294767	111294787	142	-11.03
CAediting_1524209	chrX_134546392_-	ENSG00000102606.16	ENST00000375739	hsa-miR-503-5p	111293876	111293881	6mer	111293859	111293882	146	-27.31
CAediting_1229413	chr17_67471544_+	ENSG00000102606.16	ENST00000375739	hsa-miR-548aa	111292601	111292607	7mer-m8	111292584	111292608	140	-7.46
CAediting_1229414	chr17_67471546_+	ENSG00000102606.16	ENST00000375739	hsa-miR-548aa	111292601	111292607	7mer-m8	111292584	111292608	140	-7.46
CAediting_1229415	chr17_67471547_+	ENSG00000102606.16	ENST00000375739	hsa-miR-548aa	111292601	111292607	7mer-m8	111292584	111292608	140	-7.46
CAediting_524911	chr7_5495852_-	ENSG00000102606.16	ENST00000375739	hsa-miR-589-3p	111293601	111293607	7mer-m8	111293584	111293608	154	-22.44
CAediting_524911	chr7_5495852_-	ENSG00000102606.16	ENST00000375739	hsa-miR-589-3p	111293808	111293815	8mer-1a	111293787	111293815	148	-16.53
CAediting_524911	chr7_5495852_-	ENSG00000102606.16	ENST00000375739	hsa-miR-589-3p	111292846	111292852	7mer-m8	111292831	111292853	155	-20.83
CAediting_393	chr1_1167164_+	ENSG00000102606.16	ENST00000375741	hsa-miR-200b-3p	111294781	111294786	6mer	111294767	111294787	142	-11.03
CAediting_1524209	chrX_134546392_-	ENSG00000102606.16	ENST00000375741	hsa-miR-503-5p	111293876	111293881	6mer	111293859	111293882	146	-27.31
CAediting_1229413	chr17_67471544_+	ENSG00000102606.16	ENST00000375741	hsa-miR-548aa	111292601	111292607	7mer-m8	111292584	111292608	140	-7.46
CAediting_1229414	chr17_67471546_+	ENSG00000102606.16	ENST00000375741	hsa-miR-548aa	111292601	111292607	7mer-m8	111292584	111292608	140	-7.46
CAediting_1229415	chr17_67471547_+	ENSG00000102606.16	ENST00000375741	hsa-miR-548aa	111292601	111292607	7mer-m8	111292584	111292608	140	-7.46
CAediting_524911	chr7_5495852_-	ENSG00000102606.16	ENST00000375741	hsa-miR-589-3p	111293601	111293607	7mer-m8	111293584	111293608	154	-22.44
CAediting_524911	chr7_5495852_-	ENSG00000102606.16	ENST00000375741	hsa-miR-589-3p	111293808	111293815	8mer-1a	111293787	111293815	148	-16.53
CAediting_524911	chr7_5495852_-	ENSG00000102606.16	ENST00000375741	hsa-miR-589-3p	111292846	111292852	7mer-m8	111292831	111292853	155	-20.83
CAediting_1306324	chr19_13836464_-	ENSG00000102606.16	ENST00000218789	hsa-miR-27a-3p	111303852	111303858	7mer-m8	111303840	111303859	149	-14
CAediting_1306323	chr19_13836462_-	ENSG00000102606.16	ENST00000218789	hsa-miR-27a-3p	111303852	111303858	7mer-m8	111303840	111303859	149	-14
CAediting_688080	chr9_63819626_+	ENSG00000102606.16	ENST00000218789	hsa-miR-4477b	111305565	111305571	7mer-m8	111305551	111305572	140	-9.58
CAediting_1229413	chr17_67471544_+	ENSG00000102606.16	ENST00000218789	hsa-miR-548aa	111304418	111304425	8mer-1a	111304404	111304425	153	-12.55
CAediting_1229415	chr17_67471547_+	ENSG00000102606.16	ENST00000218789	hsa-miR-548aa	111304418	111304425	8mer-1a	111304404	111304425	153	-12.55
CAediting_524911	chr7_5495852_-	ENSG00000102606.16	ENST00000218789	hsa-miR-589-3p	111304348	111304353	6mer	111304331	111304354	144	-19.37
CAediting_980496	chr14_31014685_-	ENSG00000102606.16	ENST00000218789	hsa-miR-624-3p	111305386	111305393	8mer-1a	111305373	111305393	143	-9.32
CAediting_468389	chr6_31355314_-	ENSG00000102606.16	ENST00000218789	hsa-miR-6891-5p	111304150	111304156	7mer-m8	111304139	111304157	153	-19.66
CAediting_1306324	chr19_13836464_-	ENSG00000102606.16	ENST00000375736	hsa-miR-27a-3p	111303852	111303858	7mer-m8	111303840	111303859	149	-14
CAediting_1306323	chr19_13836462_-	ENSG00000102606.16	ENST00000375736	hsa-miR-27a-3p	111303852	111303858	7mer-m8	111303840	111303859	149	-14
CAediting_688080	chr9_63819626_+	ENSG00000102606.16	ENST00000375736	hsa-miR-4477b	111305565	111305571	7mer-m8	111305551	111305572	140	-9.58
CAediting_1229413	chr17_67471544_+	ENSG00000102606.16	ENST00000375736	hsa-miR-548aa	111304418	111304425	8mer-1a	111304404	111304425	153	-12.55
CAediting_1229415	chr17_67471547_+	ENSG00000102606.16	ENST00000375736	hsa-miR-548aa	111304418	111304425	8mer-1a	111304404	111304425	153	-12.55
CAediting_524911	chr7_5495852_-	ENSG00000102606.16	ENST00000375736	hsa-miR-589-3p	111304348	111304353	6mer	111304331	111304354	144	-19.37
CAediting_980496	chr14_31014685_-	ENSG00000102606.16	ENST00000375736	hsa-miR-624-3p	111305386	111305393	8mer-1a	111305373	111305393	143	-9.32
CAediting_468389	chr6_31355314_-	ENSG00000102606.16	ENST00000375736	hsa-miR-6891-5p	111304150	111304156	7mer-m8	111304139	111304157	153	-19.66
CAediting_1306324	chr19_13836464_-	ENSG00000102606.16	ENST00000426073	hsa-miR-27a-3p	111303852	111303858	7mer-m8	111303840	111303859	149	-14
CAediting_1306323	chr19_13836462_-	ENSG00000102606.16	ENST00000426073	hsa-miR-27a-3p	111303852	111303858	7mer-m8	111303840	111303859	149	-14
CAediting_688080	chr9_63819626_+	ENSG00000102606.16	ENST00000426073	hsa-miR-4477b	111305565	111305571	7mer-m8	111305551	111305572	140	-9.58
CAediting_1229413	chr17_67471544_+	ENSG00000102606.16	ENST00000426073	hsa-miR-548aa	111304418	111304425	8mer-1a	111304404	111304425	153	-12.55
CAediting_1229415	chr17_67471547_+	ENSG00000102606.16	ENST00000426073	hsa-miR-548aa	111304418	111304425	8mer-1a	111304404	111304425	153	-12.55
CAediting_524911	chr7_5495852_-	ENSG00000102606.16	ENST00000426073	hsa-miR-589-3p	111304348	111304353	6mer	111304331	111304354	144	-19.37
CAediting_980496	chr14_31014685_-	ENSG00000102606.16	ENST00000426073	hsa-miR-624-3p	111305386	111305393	8mer-1a	111305373	111305393	143	-9.32
CAediting_468389	chr6_31355314_-	ENSG00000102606.16	ENST00000426073	hsa-miR-6891-5p	111304150	111304156	7mer-m8	111304139	111304157	153	-19.66
CAediting_393	chr1_1167164_+	ENSG00000102606.16	ENST00000375723	hsa-miR-200b-3p	111294781	111294786	6mer	111294767	111294787	142	-11.03
CAediting_1524209	chrX_134546392_-	ENSG00000102606.16	ENST00000375723	hsa-miR-503-5p	111293876	111293881	6mer	111293859	111293882	146	-27.31
CAediting_1229413	chr17_67471544_+	ENSG00000102606.16	ENST00000375723	hsa-miR-548aa	111292601	111292607	7mer-m8	111292584	111292608	140	-7.46
CAediting_1229414	chr17_67471546_+	ENSG00000102606.16	ENST00000375723	hsa-miR-548aa	111292601	111292607	7mer-m8	111292584	111292608	140	-7.46
CAediting_1229415	chr17_67471547_+	ENSG00000102606.16	ENST00000375723	hsa-miR-548aa	111292601	111292607	7mer-m8	111292584	111292608	140	-7.46
CAediting_524911	chr7_5495852_-	ENSG00000102606.16	ENST00000375723	hsa-miR-589-3p	111293601	111293607	7mer-m8	111293584	111293608	154	-22.44
CAediting_524911	chr7_5495852_-	ENSG00000102606.16	ENST00000375723	hsa-miR-589-3p	111293808	111293815	8mer-1a	111293787	111293815	148	-16.53
CAediting_524911	chr7_5495852_-	ENSG00000102606.16	ENST00000375723	hsa-miR-589-3p	111292846	111292852	7mer-m8	111292831	111292853	155	-20.83

Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for ARHGEF7

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

Top

Relation with ADAR for ARHGEF7

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
STAD	CAediting_973419	chr13_111207220_+	0.0253602471701466	0.24838356978396	.	.	.	.
STAD	CAediting_973428	chr13_111207281_+	0.0209819772572029	0.194268123878263	.	.	.	.

Top

Relation with cancer stages for ARHGEF7

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
ESCA	pathologic_stage	CAediting_973428	chr13_111207281_+	0.00800737639046626	0.390460378416964

Top

Relation with survival for ARHGEF7

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

Top

RelatedDrugs for ARHGEF7

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

RelatedDiseases for ARHGEF7

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene