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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: CDK5R1 (CAeditome ID:8851) |
Gene summary for CDK5R1 |
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Gene information | Gene symbol | CDK5R1 | Gene ID | 8851 |
Gene name | cyclin dependent kinase 5 regulatory subunit 1 | |
Synonyms | CDK5P35|CDK5R|NCK5A|p23|p25|p35|p35nck5a | |
Cytomap | 17q11.2 | |
Type of gene | protein-coding | |
Description | cyclin-dependent kinase 5 activator 1CDK5 activator 1TPKII regulatory subunitneuronal CDK5 activatorregulatory partner for CDK5 kinasetau protein kinase II 23kDa subunit | |
Modification date | 20210518 | |
UniProtAcc | Q15078 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
CDK5R1 | GO:0043539 | Cyclin-dependent kinase 5 activator 1 | 12832520 |
CDK5R1 | GO:0018105 | Cyclin-dependent kinase 5 activator 1 | 12832520 |
CDK5R1 | GO:0018107 | Cyclin-dependent kinase 5 activator 1 | 12832520 |
CDK5R1 | GO:0005654 | Cyclin-dependent kinase 5 activator 1 | 0000052 |
CDK5R1 | GO:0043231 | Cyclin-dependent kinase 5 activator 1 | 0000052 |
CDK5R1 | GO:0048471 | Cyclin-dependent kinase 5 activator 1 | 12832520 |
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RNA A-to-I events for CDK5R1 |
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CAediting_1181777(32487673, +), CAediting_1181778(32487831, +), |
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RNA editing positional annotations for CDK5R1 using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
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CAeditome ID | Position | Variant type |
CAediting_1181777 | chr17_32487673_+ | exonic |
CAediting_1181778 | chr17_32487831_+ | exonic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
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RNA A-to-I editing events in the alternative splicing sites for CDK5R1 |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CDK5R1 |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for CDK5R1 |
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The effects of the RNA editing to the miRNA binding sites for CDK5R1 |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_980496 | chr14_31014685_- | ENSG00000176749.7 | ENST00000584716 | hsa-miR-624-3p | 32489346 | 32489352 | 7mer-m8 | 32489333 | 32489353 | 160 | -24.13 |
CAediting_77128 | chr1_85133844_+ | ENSG00000176749.7 | ENST00000584716 | hsa-miR-4423-3p | 32489376 | 32489382 | 7mer-m8 | 32489363 | 32489383 | 145 | -21.23 |
CAediting_77128 | chr1_85133844_+ | ENSG00000176749.7 | ENST00000584716 | hsa-miR-4423-3p | 32489440 | 32489446 | 7mer-m8 | 32489427 | 32489447 | 145 | -15.39 |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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The effects of the RNA editing to the stability of the RNA structures for CDK5R1 |
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ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for CDK5R1 |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for CDK5R1 |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for CDK5R1 |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for CDK5R1 |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CDK5R1 |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |
CDK5R1 | C0006111 | Brain Diseases | 1 | CTD_human |
CDK5R1 | C0009241 | Cognition Disorders | 1 | CTD_human |
CDK5R1 | C0027746 | Nerve Degeneration | 1 | CTD_human |
CDK5R1 | C0036341 | Schizophrenia | 1 | PSYGENET |
CDK5R1 | C0085584 | Encephalopathies | 1 | CTD_human |