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Editing gene: KSR1 (CAeditome ID:8844)

Gene summary for KSR1

Gene summary

Gene information	Gene symbol	KSR1
	Gene ID	8844
	Gene name	kinase suppressor of ras 1
	Synonyms	KSR\|RSU2
	Cytomap	17q11.2
	Type of gene	protein-coding
	Description	kinase suppressor of Ras 1
	Modification date	20210518
	UniProtAcc	Q8IVT5
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
KSR1	GO:0005524	Kinase suppressor of Ras 1	29433126
KSR1	GO:0008022	Kinase suppressor of Ras 1	22572157
KSR1	GO:0071889	Kinase suppressor of Ras 1	29433126
KSR1	GO:0000185	Kinase suppressor of Ras 1	29433126
KSR1	GO:0005783	Kinase suppressor of Ras 1	22572157
KSR1	GO:0016020	Kinase suppressor of Ras 1	22572157
KSR1	GO:0032991	Kinase suppressor of Ras 1	22572157

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RNA A-to-I events for KSR1

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000141068.12

RNA A-to-I editing events in Cancer.

CAediting_1170925(27463310, +), CAediting_1170926(27468425, +), CAediting_1170927(27471104, +), CAediting_1170928(27472931, +), CAediting_1170929(27472935, +), CAediting_1170930(27472976, +), CAediting_1170931(27473043, +), CAediting_1170932(27483392, +), CAediting_1170933(27483402, +), CAediting_1170934(27483466, +), CAediting_1170935(27483467, +), CAediting_1170936(27483472, +), CAediting_1170937(27483476, +), CAediting_1170938(27483480, +), CAediting_1170939(27483499, +), CAediting_1170940(27483508, +), CAediting_1170941(27484442, +), CAediting_1170942(27484496, +), CAediting_1170943(27491138, +), CAediting_1170944(27514404, +), CAediting_1170945(27514605, +), CAediting_1170946(27527261, +), CAediting_1170947(27527262, +), CAediting_1170948(27528627, +), CAediting_1170949(27579622, +), CAediting_1170950(27579666, +), CAediting_1170951(27579698, +), CAediting_1170952(27579699, +), CAediting_1170953(27579700, +), CAediting_1170954(27579711, +), CAediting_1170955(27579714, +), CAediting_1170956(27579715, +), CAediting_1170957(27579716, +), CAediting_1170958(27579718, +), CAediting_1170959(27579723, +), CAediting_1170960(27579724, +), CAediting_1170961(27579725, +), CAediting_1170962(27579726, +), CAediting_1170963(27579729, +), CAediting_1170964(27579755, +), CAediting_1170965(27579756, +), CAediting_1170966(27579765, +), CAediting_1170967(27579778, +), CAediting_1170968(27579826, +), CAediting_1170969(27580841, +), CAediting_1170970(27580884, +), CAediting_1170971(27580892, +), CAediting_1170972(27580896, +), CAediting_1170973(27580906, +), CAediting_1170974(27580909, +), CAediting_1170975(27580932, +), CAediting_1170976(27580941, +), CAediting_1170977(27580947, +), CAediting_1170978(27580950, +), CAediting_1170979(27586976, +), CAediting_1170980(27587102, +), CAediting_1170981(27599026, +), CAediting_1170982(27606025, +), CAediting_1170983(27606126, +), CAediting_1170984(27606204, +), CAediting_1170985(27606906, +), CAediting_1170986(27606925, +), CAediting_1170987(27606931, +), CAediting_1170988(27606932, +), CAediting_1170989(27606935, +), CAediting_1170990(27606973, +), CAediting_1170991(27607094, +), CAediting_1170992(27617589, +), CAediting_1170993(27617597, +), CAediting_1170994(27617730, +), CAediting_1170995(27622533, +), CAediting_1170996(27623958, +),

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RNA editing positional annotations for KSR1 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1170925	chr17_27463310_+	ncRNA_intronic
CAediting_1170926	chr17_27468425_+	ncRNA_intronic
CAediting_1170927	chr17_27471104_+	ncRNA_intronic
CAediting_1170928	chr17_27472931_+	ncRNA_intronic
CAediting_1170929	chr17_27472935_+	ncRNA_intronic
CAediting_1170930	chr17_27472976_+	ncRNA_intronic
CAediting_1170931	chr17_27473043_+	ncRNA_intronic
CAediting_1170932	chr17_27483392_+	ncRNA_intronic
CAediting_1170933	chr17_27483402_+	ncRNA_intronic
CAediting_1170934	chr17_27483466_+	ncRNA_intronic
CAediting_1170935	chr17_27483467_+	ncRNA_intronic
CAediting_1170936	chr17_27483472_+	ncRNA_intronic
CAediting_1170937	chr17_27483476_+	ncRNA_intronic
CAediting_1170938	chr17_27483480_+	ncRNA_intronic
CAediting_1170939	chr17_27483499_+	ncRNA_intronic
CAediting_1170940	chr17_27483508_+	ncRNA_intronic
CAediting_1170941	chr17_27484442_+	ncRNA_intronic
CAediting_1170942	chr17_27484496_+	ncRNA_intronic
CAediting_1170943	chr17_27491138_+	ncRNA_intronic
CAediting_1170944	chr17_27514404_+	ncRNA_intronic
CAediting_1170945	chr17_27514605_+	ncRNA_intronic
CAediting_1170946	chr17_27527261_+	ncRNA_intronic
CAediting_1170947	chr17_27527262_+	ncRNA_intronic
CAediting_1170948	chr17_27528627_+	ncRNA_intronic
CAediting_1170949	chr17_27579622_+	ncRNA_exonic
CAediting_1170950	chr17_27579666_+	ncRNA_exonic
CAediting_1170951	chr17_27579698_+	ncRNA_exonic
CAediting_1170952	chr17_27579699_+	ncRNA_exonic
CAediting_1170953	chr17_27579700_+	ncRNA_exonic
CAediting_1170954	chr17_27579711_+	ncRNA_exonic
CAediting_1170955	chr17_27579714_+	ncRNA_exonic
CAediting_1170956	chr17_27579715_+	ncRNA_exonic
CAediting_1170957	chr17_27579716_+	ncRNA_exonic
CAediting_1170958	chr17_27579718_+	ncRNA_exonic
CAediting_1170959	chr17_27579723_+	ncRNA_exonic
CAediting_1170960	chr17_27579724_+	ncRNA_exonic
CAediting_1170961	chr17_27579725_+	ncRNA_exonic
CAediting_1170962	chr17_27579726_+	ncRNA_exonic
CAediting_1170963	chr17_27579729_+	ncRNA_exonic
CAediting_1170964	chr17_27579755_+	ncRNA_exonic
CAediting_1170965	chr17_27579756_+	ncRNA_exonic
CAediting_1170966	chr17_27579765_+	ncRNA_exonic
CAediting_1170967	chr17_27579778_+	ncRNA_exonic
CAediting_1170968	chr17_27579826_+	ncRNA_exonic
CAediting_1170969	chr17_27580841_+	ncRNA_intronic
CAediting_1170970	chr17_27580884_+	ncRNA_intronic
CAediting_1170971	chr17_27580892_+	ncRNA_intronic
CAediting_1170972	chr17_27580896_+	ncRNA_intronic
CAediting_1170973	chr17_27580906_+	ncRNA_intronic
CAediting_1170974	chr17_27580909_+	ncRNA_intronic
CAediting_1170975	chr17_27580932_+	ncRNA_intronic
CAediting_1170976	chr17_27580941_+	ncRNA_intronic
CAediting_1170977	chr17_27580947_+	ncRNA_intronic
CAediting_1170978	chr17_27580950_+	ncRNA_intronic
CAediting_1170979	chr17_27586976_+	ncRNA_intronic
CAediting_1170980	chr17_27587102_+	ncRNA_intronic
CAediting_1170981	chr17_27599026_+	ncRNA_intronic
CAediting_1170982	chr17_27606025_+	intronic
CAediting_1170983	chr17_27606126_+	intronic
CAediting_1170984	chr17_27606204_+	intronic
CAediting_1170985	chr17_27606906_+	intronic
CAediting_1170986	chr17_27606925_+	intronic
CAediting_1170987	chr17_27606931_+	intronic
CAediting_1170988	chr17_27606932_+	intronic
CAediting_1170989	chr17_27606935_+	intronic
CAediting_1170990	chr17_27606973_+	intronic
CAediting_1170991	chr17_27607094_+	intronic
CAediting_1170992	chr17_27617589_+	intronic
CAediting_1170993	chr17_27617597_+	intronic
CAediting_1170994	chr17_27617730_+	intronic
CAediting_1170995	chr17_27622533_+	UTR3
CAediting_1170996	chr17_27623958_+	UTR3

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1170925	chr17_27463310_+	SINE	Alu	AluJb
CAediting_1170926	chr17_27468425_+	SINE	Alu	AluSz
CAediting_1170927	chr17_27471104_+	SINE	Alu	AluSz6
CAediting_1170928	chr17_27472931_+	SINE	Alu	AluJb
CAediting_1170929	chr17_27472935_+	SINE	Alu	AluJb
CAediting_1170930	chr17_27472976_+	SINE	Alu	AluJb
CAediting_1170931	chr17_27473043_+	SINE	Alu	AluJb
CAediting_1170932	chr17_27483392_+	SINE	Alu	AluSp
CAediting_1170933	chr17_27483402_+	SINE	Alu	AluSp
CAediting_1170934	chr17_27483466_+	SINE	Alu	AluSp
CAediting_1170935	chr17_27483467_+	SINE	Alu	AluSp
CAediting_1170936	chr17_27483472_+	SINE	Alu	AluSp
CAediting_1170937	chr17_27483476_+	SINE	Alu	AluSp
CAediting_1170938	chr17_27483480_+	SINE	Alu	AluSp
CAediting_1170939	chr17_27483499_+	SINE	Alu	AluSp
CAediting_1170940	chr17_27483508_+	SINE	Alu	AluSp
CAediting_1170941	chr17_27484442_+	SINE	Alu	AluSz
CAediting_1170942	chr17_27484496_+	SINE	Alu	AluSz
CAediting_1170943	chr17_27491138_+	SINE	Alu	AluJr
CAediting_1170944	chr17_27514404_+	SINE	Alu	AluSq2
CAediting_1170945	chr17_27514605_+	SINE	Alu	AluSq2
CAediting_1170946	chr17_27527261_+	SINE	Alu	AluJb
CAediting_1170947	chr17_27527262_+	SINE	Alu	AluJb
CAediting_1170948	chr17_27528627_+	SINE	Alu	AluJo
CAediting_1170949	chr17_27579622_+	SINE	Alu	AluSz6
CAediting_1170950	chr17_27579666_+	SINE	Alu	AluSz6
CAediting_1170951	chr17_27579698_+	SINE	Alu	AluSz6
CAediting_1170952	chr17_27579699_+	SINE	Alu	AluSz6
CAediting_1170953	chr17_27579700_+	SINE	Alu	AluSz6
CAediting_1170954	chr17_27579711_+	SINE	Alu	AluSz6
CAediting_1170955	chr17_27579714_+	SINE	Alu	AluSz6
CAediting_1170956	chr17_27579715_+	SINE	Alu	AluSz6
CAediting_1170957	chr17_27579716_+	SINE	Alu	AluSz6
CAediting_1170958	chr17_27579718_+	SINE	Alu	AluSz6
CAediting_1170959	chr17_27579723_+	SINE	Alu	AluSz6
CAediting_1170960	chr17_27579724_+	SINE	Alu	AluSz6
CAediting_1170961	chr17_27579725_+	SINE	Alu	AluSz6
CAediting_1170962	chr17_27579726_+	SINE	Alu	AluSz6
CAediting_1170963	chr17_27579729_+	SINE	Alu	AluSz6
CAediting_1170964	chr17_27579755_+	SINE	Alu	AluSz6
CAediting_1170965	chr17_27579756_+	SINE	Alu	AluSz6
CAediting_1170966	chr17_27579765_+	SINE	Alu	AluSz6
CAediting_1170967	chr17_27579778_+	SINE	Alu	AluSz6
CAediting_1170968	chr17_27579826_+	SINE	Alu	AluSz6
CAediting_1170969	chr17_27580841_+	SINE	Alu	AluSz6
CAediting_1170970	chr17_27580884_+	SINE	Alu	AluSz6
CAediting_1170971	chr17_27580892_+	SINE	Alu	AluSz6
CAediting_1170972	chr17_27580896_+	SINE	Alu	AluSz6
CAediting_1170973	chr17_27580906_+	SINE	Alu	AluSz6
CAediting_1170974	chr17_27580909_+	SINE	Alu	AluSz6
CAediting_1170975	chr17_27580932_+	SINE	Alu	AluSz6
CAediting_1170976	chr17_27580941_+	SINE	Alu	AluSz6
CAediting_1170977	chr17_27580947_+	SINE	Alu	AluSz6
CAediting_1170978	chr17_27580950_+	SINE	Alu	AluSz6
CAediting_1170979	chr17_27586976_+	SINE	Alu	AluSx1
CAediting_1170980	chr17_27587102_+	SINE	Alu	AluSx1
CAediting_1170981	chr17_27599026_+	DNA	TcMar-Tigger	Tigger3b
CAediting_1170982	chr17_27606025_+	SINE	Alu	AluJo
CAediting_1170983	chr17_27606126_+	SINE	Alu	AluJo
CAediting_1170984	chr17_27606204_+	SINE	Alu	AluJo
CAediting_1170985	chr17_27606906_+	SINE	Alu	AluSx
CAediting_1170986	chr17_27606925_+	SINE	Alu	AluSx
CAediting_1170987	chr17_27606931_+	SINE	Alu	AluSx
CAediting_1170988	chr17_27606932_+	SINE	Alu	AluSx
CAediting_1170989	chr17_27606935_+	SINE	Alu	AluSx
CAediting_1170990	chr17_27606973_+	SINE	Alu	AluSx
CAediting_1170991	chr17_27607094_+	SINE	Alu	AluSx
CAediting_1170992	chr17_27617589_+	SINE	Alu	AluSq2
CAediting_1170993	chr17_27617597_+	SINE	Alu	AluSq2
CAediting_1170994	chr17_27617730_+	SINE	Alu	AluSq2

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RNA A-to-I editing events in the alternative splicing sites for KSR1

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000141068.12.KSR1.

Correlation between RNA A-to-I editing and PSI for ENSG00000141068.12.KSR1.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for KSR1

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for KSR1

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for KSR1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1170996	chr17_27623958_+	ENSG00000141068.12	ENST00000398988	hsa-miR-7977	27623954	27623961	8mer-1a	27623944	27623961	150.00	-20.06
CAediting_1170995	chr17_27622533_+	ENSG00000141068.12	ENST00000398988	hsa-miR-4680-5p	27622531	27622537	7mer-m8	27622515	27622538	160.00	-20.62
CAediting_1170995	chr17_27622533_+	ENSG00000141068.12	ENST00000398988	hsa-miR-618	27622531	27622536	6mer	27622516	27622537	143.00	-20.87
CAediting_1170995	chr17_27622533_+	ENSG00000141068.12	ENST00000398988	hsa-miR-6817-3p	27622528	27622534	7mer-m8	27622517	27622535	144.00	-14.66
CAediting_1170995	chr17_27622533_+	ENSG00000141068.12	ENST00000582410	hsa-miR-4680-5p	27622531	27622537	7mer-m8	27622515	27622538	160.00	-20.62
CAediting_1170995	chr17_27622533_+	ENSG00000141068.12	ENST00000582410	hsa-miR-618	27622531	27622536	6mer	27622516	27622537	143.00	-20.87
CAediting_1170995	chr17_27622533_+	ENSG00000141068.12	ENST00000582410	hsa-miR-6817-3p	27622528	27622534	7mer-m8	27622517	27622535	144.00	-14.66

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1170996	chr17_27623958_+	ENSG00000141068.12	ENST00000398988	hsa-miR-384	27623955	27623961	7mer-m8	27623943	27623962	148	-11.47
CAediting_1170995	chr17_27622533_+	ENSG00000141068.12	ENST00000398988	hsa-miR-4743-3p	27622527	27622533	7mer-1a	27622513	27622533	150	-22.81
CAediting_1170996	chr17_27623958_+	ENSG00000141068.12	ENST00000398988	hsa-miR-7975	27623955	27623961	7mer-1a	27623944	27623961	141	-17.57
CAediting_1170995	chr17_27622533_+	ENSG00000141068.12	ENST00000582410	hsa-miR-4743-3p	27622527	27622533	7mer-1a	27622513	27622533	150	-22.81

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_748296	chr10_51299626_+	ENSG00000141068.12	ENST00000398988	hsa-miR-605-3p	27622106	27622111	6mer	27622096	27622119	142	-20.44
CAediting_748296	chr10_51299626_+	ENSG00000141068.12	ENST00000398988	hsa-miR-605-3p	27622112	27622118	7mer-m8	27622096	27622119	142	-20.44
CAediting_748296	chr10_51299626_+	ENSG00000141068.12	ENST00000398988	hsa-miR-605-3p	27626373	27626379	7mer-m8	27626359	27626380	140	-16.59
CAediting_393	chr1_1167164_+	ENSG00000141068.12	ENST00000398988	hsa-miR-200b-3p	27623310	27623317	8mer-1a	27623294	27623317	146	-14.82
CAediting_393	chr1_1167164_+	ENSG00000141068.12	ENST00000398988	hsa-miR-200b-3p	27622737	27622743	7mer-m8	27622722	27622744	156	-19.9
CAediting_748296	chr10_51299626_+	ENSG00000141068.12	ENST00000398982	hsa-miR-605-3p	27622106	27622111	6mer	27622096	27622119	142	-20.44
CAediting_748296	chr10_51299626_+	ENSG00000141068.12	ENST00000398982	hsa-miR-605-3p	27622112	27622118	7mer-m8	27622096	27622119	142	-20.44
CAediting_748296	chr10_51299626_+	ENSG00000141068.12	ENST00000582410	hsa-miR-605-3p	27622106	27622111	6mer	27622096	27622119	142	-20.44
CAediting_748296	chr10_51299626_+	ENSG00000141068.12	ENST00000582410	hsa-miR-605-3p	27622112	27622118	7mer-m8	27622096	27622119	142	-20.44
CAediting_393	chr1_1167164_+	ENSG00000141068.12	ENST00000582410	hsa-miR-200b-3p	27623310	27623317	8mer-1a	27623294	27623317	146	-14.82
CAediting_393	chr1_1167164_+	ENSG00000141068.12	ENST00000582410	hsa-miR-200b-3p	27622737	27622743	7mer-m8	27622722	27622744	156	-19.9
CAediting_1229414	chr17_67471546_+	ENSG00000141068.12	ENST00000398988	hsa-miR-548aa	27622252	27622258	7mer-m8	27622234	27622259	142	-14.22
CAediting_1229414	chr17_67471546_+	ENSG00000141068.12	ENST00000398988	hsa-miR-548aa	27625408	27625414	7mer-m8	27625388	27625415	150	-14.81
CAediting_1229415	chr17_67471547_+	ENSG00000141068.12	ENST00000398988	hsa-miR-548aa	27624199	27624205	7mer-m8	27624178	27624206	141	-18.3
CAediting_1229415	chr17_67471547_+	ENSG00000141068.12	ENST00000398988	hsa-miR-548aa	27622389	27622395	7mer-m8	27622370	27622396	157	-20.51
CAediting_1306323	chr19_13836462_-	ENSG00000141068.12	ENST00000398988	hsa-miR-27a-3p	27621990	27621996	7mer-m8	27621978	27621997	163	-18.44
CAediting_86358	chr1_109598906_+	ENSG00000141068.12	ENST00000398988	hsa-miR-197-5p	27622310	27622316	7mer-m8	27622297	27622317	148	-19.34
CAediting_228905	chr2_188297554_+	ENSG00000141068.12	ENST00000398988	hsa-miR-561-3p	27624612	27624618	7mer-m8	27624598	27624619	141	-11.83
CAediting_524911	chr7_5495852_-	ENSG00000141068.12	ENST00000398988	hsa-miR-589-3p	27624429	27624436	8mer-1a	27624413	27624436	140	-15.58
CAediting_524911	chr7_5495852_-	ENSG00000141068.12	ENST00000398988	hsa-miR-589-3p	27624755	27624762	8mer-1a	27624737	27624762	150	-21.06
CAediting_524911	chr7_5495852_-	ENSG00000141068.12	ENST00000398988	hsa-miR-589-3p	27624888	27624894	7mer-m8	27624873	27624895	141	-13.61
CAediting_1306323	chr19_13836462_-	ENSG00000141068.12	ENST00000398982	hsa-miR-27a-3p	27621990	27621996	7mer-m8	27621978	27621997	163	-18.44
CAediting_1229414	chr17_67471546_+	ENSG00000141068.12	ENST00000582410	hsa-miR-548aa	27622252	27622258	7mer-m8	27622234	27622259	142	-14.22
CAediting_1229415	chr17_67471547_+	ENSG00000141068.12	ENST00000582410	hsa-miR-548aa	27622389	27622395	7mer-m8	27622370	27622396	157	-20.51
CAediting_1306323	chr19_13836462_-	ENSG00000141068.12	ENST00000582410	hsa-miR-27a-3p	27621990	27621996	7mer-m8	27621978	27621997	163	-18.44
CAediting_86358	chr1_109598906_+	ENSG00000141068.12	ENST00000582410	hsa-miR-197-5p	27622310	27622316	7mer-m8	27622297	27622317	148	-19.34
CAediting_468389	chr6_31355314_-	ENSG00000141068.12	ENST00000398988	hsa-miR-6891-5p	27624914	27624920	7mer-m8	27624903	27624921	145	-16.88

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_393	chr1_1167164_+	ENSG00000141068.12	ENST00000398988	hsa-miR-200b-3p	27622909	27622916	8mer-1a	27622895	27622916	140	-11.14
CAediting_1306323	chr19_13836462_-	ENSG00000141068.12	ENST00000398988	hsa-miR-27a-3p	27625717	27625724	8mer-1a	27625704	27625724	151	-17.9
CAediting_1306324	chr19_13836464_-	ENSG00000141068.12	ENST00000398988	hsa-miR-27a-3p	27625717	27625724	8mer-1a	27625704	27625724	151	-17.9
CAediting_1306323	chr19_13836462_-	ENSG00000141068.12	ENST00000398988	hsa-miR-27a-3p	27625742	27625749	8mer-1a	27625728	27625749	147	-17.44
CAediting_1306324	chr19_13836464_-	ENSG00000141068.12	ENST00000398988	hsa-miR-27a-3p	27625742	27625749	8mer-1a	27625728	27625749	147	-17.44
CAediting_1368054	chr19_46709310_-	ENSG00000141068.12	ENST00000398988	hsa-miR-320e	27622555	27622561	7mer-m8	27622545	27622562	140	-10.9
CAediting_604450	chr7_133034877_-	ENSG00000141068.12	ENST00000398988	hsa-miR-3654	27623370	27623377	8mer-1a	27623359	27623377	140	-17.53
CAediting_77128	chr1_85133844_+	ENSG00000141068.12	ENST00000398988	hsa-miR-4423-3p	27622347	27622353	7mer-m8	27622333	27622354	142	-15.21
CAediting_1054808	chr15_66496985_-	ENSG00000141068.12	ENST00000398988	hsa-miR-4512	27625486	27625491	6mer	27625471	27625492	148	-29.1
CAediting_1524209	chrX_134546392_-	ENSG00000141068.12	ENST00000398988	hsa-miR-503-5p	27623409	27623415	7mer-m8	27623394	27623416	152	-19.28
CAediting_1229413	chr17_67471544_+	ENSG00000141068.12	ENST00000398988	hsa-miR-548aa	27623401	27623407	7mer-m8	27623384	27623408	147	-10.45
CAediting_1229414	chr17_67471546_+	ENSG00000141068.12	ENST00000398988	hsa-miR-548aa	27623401	27623407	7mer-m8	27623384	27623408	147	-10.45
CAediting_1229415	chr17_67471547_+	ENSG00000141068.12	ENST00000398988	hsa-miR-548aa	27623401	27623407	7mer-m8	27623384	27623408	147	-10.45
CAediting_117844	chr1_162342605_+	ENSG00000141068.12	ENST00000398988	hsa-miR-556-3p	27623667	27623674	8mer-1a	27623650	27623674	153	-10.41
CAediting_748296	chr10_51299626_+	ENSG00000141068.12	ENST00000398988	hsa-miR-605-3p	27622305	27622311	7mer-m8	27622287	27622312	152	-18.53
CAediting_980496	chr14_31014685_-	ENSG00000141068.12	ENST00000398988	hsa-miR-624-3p	27623744	27623751	8mer-1a	27623731	27623751	143	-10.17
CAediting_393	chr1_1167164_+	ENSG00000141068.12	ENST00000582410	hsa-miR-200b-3p	27622909	27622916	8mer-1a	27622895	27622916	140	-11.14
CAediting_1368054	chr19_46709310_-	ENSG00000141068.12	ENST00000582410	hsa-miR-320e	27622555	27622561	7mer-m8	27622545	27622562	140	-10.9
CAediting_77128	chr1_85133844_+	ENSG00000141068.12	ENST00000582410	hsa-miR-4423-3p	27622347	27622353	7mer-m8	27622333	27622354	142	-15.21
CAediting_1524209	chrX_134546392_-	ENSG00000141068.12	ENST00000582410	hsa-miR-503-5p	27623409	27623415	7mer-m8	27623394	27623416	152	-19.28
CAediting_1229413	chr17_67471544_+	ENSG00000141068.12	ENST00000582410	hsa-miR-548aa	27623401	27623407	7mer-m8	27623384	27623408	147	-10.45
CAediting_1229414	chr17_67471546_+	ENSG00000141068.12	ENST00000582410	hsa-miR-548aa	27623401	27623407	7mer-m8	27623384	27623408	147	-10.45
CAediting_1229415	chr17_67471547_+	ENSG00000141068.12	ENST00000582410	hsa-miR-548aa	27623401	27623407	7mer-m8	27623384	27623408	147	-10.45
CAediting_748296	chr10_51299626_+	ENSG00000141068.12	ENST00000582410	hsa-miR-605-3p	27622305	27622311	7mer-m8	27622287	27622312	152	-18.53

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for KSR1

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for KSR1

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
LGG	CAediting_1170996	chr17_27623958_+	.	.	0.0320150497905766	0.20650147349887	.	.

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Relation with cancer stages for KSR1

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for KSR1

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for KSR1

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for KSR1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene