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Editing gene: PROM1 (CAeditome ID:8842)

Gene summary for PROM1

Gene summary

Gene information	Gene symbol	PROM1
	Gene ID	8842
	Gene name	prominin 1
	Synonyms	AC133\|CD133\|CORD12\|MCDR2\|MSTP061\|PROML1\|RP41\|STGD4
	Cytomap	4p15.32
	Type of gene	protein-coding
	Description	prominin-1antigen AC133hPromininhematopoietic stem cell antigenprominin-like protein 1
	Modification date	20210531
	UniProtAcc	O43490
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
PROM1	GO:0042805	Prominin-1	18654668
PROM1	GO:0005783	Prominin-1	24556617
PROM1	GO:0005793	Prominin-1	24556617
PROM1	GO:0005886	Prominin-1	24556617
PROM1	GO:0009986	Prominin-1	16809613
PROM1	GO:0009986	Prominin-1	19384922
PROM1	GO:0042622	Prominin-1	18654668
PROM1	GO:0070062	Prominin-1	21082674

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RNA A-to-I events for PROM1

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000007062.10

RNA A-to-I editing events in Cancer.

CAediting_350723(15969654, -), CAediting_350724(15969684, -), CAediting_350725(15969714, -), CAediting_350726(15969724, -), CAediting_350727(15969736, -), CAediting_350728(15969740, -), CAediting_350729(15969832, -), CAediting_350730(15969863, -), CAediting_350731(15970114, -), CAediting_350732(15970251, -), CAediting_350733(15970389, -), CAediting_350734(15970390, -), CAediting_350735(15972367, -), CAediting_350736(15973198, -), CAediting_350737(15973209, -), CAediting_350738(15973215, -), CAediting_350739(15973216, -), CAediting_350740(15973242, -), CAediting_350741(15973243, -), CAediting_350742(15973255, -), CAediting_350743(15973281, -), CAediting_350744(15973284, -), CAediting_350745(15973298, -), CAediting_350746(15973299, -), CAediting_350747(15973303, -), CAediting_350748(15973315, -), CAediting_350749(15973317, -), CAediting_350750(15973323, -), CAediting_350751(15973325, -), CAediting_350752(15973335, -), CAediting_350753(15973347, -), CAediting_350754(15973360, -), CAediting_350755(15973364, -), CAediting_350756(15973365, -), CAediting_350757(15973378, -), CAediting_350758(15973384, -), CAediting_350759(15973385, -), CAediting_350760(15973390, -), CAediting_350761(15973395, -), CAediting_350762(15973400, -), CAediting_350763(15973409, -), CAediting_350764(15973438, -), CAediting_350765(15973440, -), CAediting_350766(15975280, -), CAediting_350767(15975331, -), CAediting_350768(15975357, -), CAediting_350769(15975358, -), CAediting_350770(15975364, -), CAediting_350771(15975403, -), CAediting_350772(15975422, -), CAediting_350773(15975425, -), CAediting_350774(15975460, -), CAediting_350775(15976981, -), CAediting_350776(15977684, -), CAediting_350777(15977695, -), CAediting_350778(15977696, -), CAediting_350779(15977701, -), CAediting_350780(15977704, -), CAediting_350781(15977710, -), CAediting_350782(15977737, -), CAediting_350783(15977763, -), CAediting_350784(15977766, -), CAediting_350785(15977767, -), CAediting_350786(15977768, -), CAediting_350787(15977769, -), CAediting_350788(15977777, -), CAediting_350789(15977779, -), CAediting_350790(15977801, -), CAediting_350791(15977818, -), CAediting_350792(15977832, -), CAediting_350793(15977892, -), CAediting_350794(15977893, -), CAediting_350795(15978234, -), CAediting_350796(15981424, -), CAediting_350797(15988015, -), CAediting_350798(16003716, -), CAediting_350799(16003733, -), CAediting_350800(16005244, -), CAediting_350801(16009695, -), CAediting_350802(16009710, -), CAediting_350803(16010596, -), CAediting_350804(16010641, -), CAediting_350805(16010719, -), CAediting_350806(16010776, -), CAediting_350807(16042033, -), CAediting_350808(16042081, -), CAediting_350809(16050478, -), CAediting_350810(16052575, -), CAediting_350811(16052606, -), CAediting_350812(16052776, -), CAediting_350813(16053981, -), CAediting_350814(16053982, -), CAediting_350815(16054088, -), CAediting_350816(16059666, -), CAediting_350817(16060465, -), CAediting_350818(16062030, -),

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RNA editing positional annotations for PROM1 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_350723	chr4_15969654_-	ncRNA_intronic
CAediting_350724	chr4_15969684_-	ncRNA_intronic
CAediting_350725	chr4_15969714_-	ncRNA_intronic
CAediting_350726	chr4_15969724_-	ncRNA_intronic
CAediting_350727	chr4_15969736_-	ncRNA_intronic
CAediting_350728	chr4_15969740_-	ncRNA_intronic
CAediting_350729	chr4_15969832_-	ncRNA_intronic
CAediting_350730	chr4_15969863_-	ncRNA_intronic
CAediting_350731	chr4_15970114_-	ncRNA_intronic
CAediting_350732	chr4_15970251_-	ncRNA_intronic
CAediting_350733	chr4_15970389_-	ncRNA_intronic
CAediting_350734	chr4_15970390_-	ncRNA_intronic
CAediting_350735	chr4_15972367_-	intronic
CAediting_350736	chr4_15973198_-	intronic
CAediting_350737	chr4_15973209_-	intronic
CAediting_350738	chr4_15973215_-	intronic
CAediting_350739	chr4_15973216_-	intronic
CAediting_350740	chr4_15973242_-	intronic
CAediting_350741	chr4_15973243_-	intronic
CAediting_350742	chr4_15973255_-	intronic
CAediting_350743	chr4_15973281_-	intronic
CAediting_350744	chr4_15973284_-	intronic
CAediting_350745	chr4_15973298_-	intronic
CAediting_350746	chr4_15973299_-	intronic
CAediting_350747	chr4_15973303_-	intronic
CAediting_350748	chr4_15973315_-	intronic
CAediting_350749	chr4_15973317_-	intronic
CAediting_350750	chr4_15973323_-	intronic
CAediting_350751	chr4_15973325_-	intronic
CAediting_350752	chr4_15973335_-	intronic
CAediting_350753	chr4_15973347_-	intronic
CAediting_350754	chr4_15973360_-	intronic
CAediting_350755	chr4_15973364_-	intronic
CAediting_350756	chr4_15973365_-	intronic
CAediting_350757	chr4_15973378_-	intronic
CAediting_350758	chr4_15973384_-	intronic
CAediting_350759	chr4_15973385_-	intronic
CAediting_350760	chr4_15973390_-	intronic
CAediting_350761	chr4_15973395_-	intronic
CAediting_350762	chr4_15973400_-	intronic
CAediting_350763	chr4_15973409_-	intronic
CAediting_350764	chr4_15973438_-	intronic
CAediting_350765	chr4_15973440_-	intronic
CAediting_350766	chr4_15975280_-	intronic
CAediting_350767	chr4_15975331_-	intronic
CAediting_350768	chr4_15975357_-	intronic
CAediting_350769	chr4_15975358_-	intronic
CAediting_350770	chr4_15975364_-	intronic
CAediting_350771	chr4_15975403_-	intronic
CAediting_350772	chr4_15975422_-	intronic
CAediting_350773	chr4_15975425_-	intronic
CAediting_350774	chr4_15975460_-	intronic
CAediting_350775	chr4_15976981_-	intronic
CAediting_350776	chr4_15977684_-	intronic
CAediting_350777	chr4_15977695_-	intronic
CAediting_350778	chr4_15977696_-	intronic
CAediting_350779	chr4_15977701_-	intronic
CAediting_350780	chr4_15977704_-	intronic
CAediting_350781	chr4_15977710_-	intronic
CAediting_350782	chr4_15977737_-	intronic
CAediting_350783	chr4_15977763_-	intronic
CAediting_350784	chr4_15977766_-	intronic
CAediting_350785	chr4_15977767_-	intronic
CAediting_350786	chr4_15977768_-	intronic
CAediting_350787	chr4_15977769_-	intronic
CAediting_350788	chr4_15977777_-	intronic
CAediting_350789	chr4_15977779_-	intronic
CAediting_350790	chr4_15977801_-	intronic
CAediting_350791	chr4_15977818_-	intronic
CAediting_350792	chr4_15977832_-	intronic
CAediting_350793	chr4_15977892_-	intronic
CAediting_350794	chr4_15977893_-	intronic
CAediting_350795	chr4_15978234_-	intronic
CAediting_350796	chr4_15981424_-	intronic
CAediting_350797	chr4_15988015_-	intronic
CAediting_350798	chr4_16003716_-	intronic
CAediting_350799	chr4_16003733_-	intronic
CAediting_350800	chr4_16005244_-	intronic
CAediting_350801	chr4_16009695_-	intronic
CAediting_350802	chr4_16009710_-	intronic
CAediting_350803	chr4_16010596_-	intronic
CAediting_350804	chr4_16010641_-	intronic
CAediting_350805	chr4_16010719_-	intronic
CAediting_350806	chr4_16010776_-	intronic
CAediting_350807	chr4_16042033_-	intronic
CAediting_350808	chr4_16042081_-	intronic
CAediting_350809	chr4_16050478_-	intronic
CAediting_350810	chr4_16052575_-	intronic
CAediting_350811	chr4_16052606_-	intronic
CAediting_350812	chr4_16052776_-	intronic
CAediting_350813	chr4_16053981_-	intronic
CAediting_350814	chr4_16053982_-	intronic
CAediting_350815	chr4_16054088_-	intronic
CAediting_350816	chr4_16059666_-	intronic
CAediting_350817	chr4_16060465_-	intronic
CAediting_350818	chr4_16062030_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_350723	chr4_15969654_-	SINE	Alu	AluSx1
CAediting_350724	chr4_15969684_-	SINE	Alu	AluSx1
CAediting_350725	chr4_15969714_-	SINE	Alu	AluSx1
CAediting_350726	chr4_15969724_-	SINE	Alu	AluSx1
CAediting_350727	chr4_15969736_-	SINE	Alu	AluSx1
CAediting_350728	chr4_15969740_-	SINE	Alu	AluSx1
CAediting_350729	chr4_15969832_-	SINE	Alu	AluSx1
CAediting_350730	chr4_15969863_-	SINE	Alu	AluSx1
CAediting_350731	chr4_15970114_-	SINE	Alu	AluJo
CAediting_350732	chr4_15970251_-	SINE	Alu	AluSx1
CAediting_350733	chr4_15970389_-	SINE	Alu	AluSx1
CAediting_350734	chr4_15970390_-	SINE	Alu	AluSx1
CAediting_350735	chr4_15972367_-	LTR	ERVL-MaLR	MSTD
CAediting_350736	chr4_15973198_-	SINE	Alu	AluSz
CAediting_350737	chr4_15973209_-	SINE	Alu	AluSz
CAediting_350738	chr4_15973215_-	SINE	Alu	AluSz
CAediting_350739	chr4_15973216_-	SINE	Alu	AluSz
CAediting_350740	chr4_15973242_-	SINE	Alu	AluSz
CAediting_350741	chr4_15973243_-	SINE	Alu	AluSz
CAediting_350742	chr4_15973255_-	SINE	Alu	AluSz
CAediting_350743	chr4_15973281_-	SINE	Alu	AluSz
CAediting_350744	chr4_15973284_-	SINE	Alu	AluSz
CAediting_350745	chr4_15973298_-	SINE	Alu	AluSz
CAediting_350746	chr4_15973299_-	SINE	Alu	AluSz
CAediting_350747	chr4_15973303_-	SINE	Alu	AluSz
CAediting_350748	chr4_15973315_-	SINE	Alu	AluSz
CAediting_350749	chr4_15973317_-	SINE	Alu	AluSz
CAediting_350750	chr4_15973323_-	SINE	Alu	AluSz
CAediting_350751	chr4_15973325_-	SINE	Alu	AluSz
CAediting_350752	chr4_15973335_-	SINE	Alu	AluSz
CAediting_350753	chr4_15973347_-	SINE	Alu	AluSz
CAediting_350754	chr4_15973360_-	SINE	Alu	AluSz
CAediting_350755	chr4_15973364_-	SINE	Alu	AluSz
CAediting_350756	chr4_15973365_-	SINE	Alu	AluSz
CAediting_350757	chr4_15973378_-	SINE	Alu	AluSz
CAediting_350758	chr4_15973384_-	SINE	Alu	AluSz
CAediting_350759	chr4_15973385_-	SINE	Alu	AluSz
CAediting_350760	chr4_15973390_-	SINE	Alu	AluSz
CAediting_350761	chr4_15973395_-	SINE	Alu	AluSz
CAediting_350762	chr4_15973400_-	SINE	Alu	AluSz
CAediting_350763	chr4_15973409_-	SINE	Alu	AluSz
CAediting_350764	chr4_15973438_-	SINE	Alu	AluSz
CAediting_350765	chr4_15973440_-	SINE	Alu	AluSz
CAediting_350766	chr4_15975280_-	SINE	Alu	AluSx3
CAediting_350767	chr4_15975331_-	SINE	Alu	AluSx3
CAediting_350768	chr4_15975357_-	SINE	Alu	AluSx3
CAediting_350769	chr4_15975358_-	SINE	Alu	AluSx3
CAediting_350770	chr4_15975364_-	SINE	Alu	AluSx3
CAediting_350771	chr4_15975403_-	SINE	Alu	AluSx3
CAediting_350772	chr4_15975422_-	SINE	Alu	AluSx3
CAediting_350773	chr4_15975425_-	SINE	Alu	AluSx3
CAediting_350774	chr4_15975460_-	SINE	Alu	AluSx3
CAediting_350775	chr4_15976981_-	LTR	ERVL	ERV3-16A3_LTR
CAediting_350776	chr4_15977684_-	SINE	Alu	AluSc8
CAediting_350777	chr4_15977695_-	SINE	Alu	AluSc8
CAediting_350778	chr4_15977696_-	SINE	Alu	AluSc8
CAediting_350779	chr4_15977701_-	SINE	Alu	AluSc8
CAediting_350780	chr4_15977704_-	SINE	Alu	AluSc8
CAediting_350781	chr4_15977710_-	SINE	Alu	AluSc8
CAediting_350782	chr4_15977737_-	SINE	Alu	AluSc8
CAediting_350783	chr4_15977763_-	SINE	Alu	AluSc8
CAediting_350784	chr4_15977766_-	SINE	Alu	AluSc8
CAediting_350785	chr4_15977767_-	SINE	Alu	AluSc8
CAediting_350786	chr4_15977768_-	SINE	Alu	AluSc8
CAediting_350787	chr4_15977769_-	SINE	Alu	AluSc8
CAediting_350788	chr4_15977777_-	SINE	Alu	AluSc8
CAediting_350789	chr4_15977779_-	SINE	Alu	AluSc8
CAediting_350790	chr4_15977801_-	SINE	Alu	AluSc8
CAediting_350791	chr4_15977818_-	SINE	Alu	AluSc8
CAediting_350792	chr4_15977832_-	SINE	Alu	AluSc8
CAediting_350793	chr4_15977892_-	SINE	Alu	AluSc8
CAediting_350794	chr4_15977893_-	SINE	Alu	AluSc8
CAediting_350795	chr4_15978234_-	LTR	ERVL-MaLR	MLT1A0
CAediting_350796	chr4_15981424_-	SINE	Alu	AluSx3
CAediting_350797	chr4_15988015_-	SINE	Alu	AluY
CAediting_350798	chr4_16003716_-	SINE	Alu	AluJr
CAediting_350799	chr4_16003733_-	SINE	Alu	AluJr
CAediting_350800	chr4_16005244_-	SINE	Alu	AluSz6
CAediting_350801	chr4_16009695_-	SINE	Alu	AluSx
CAediting_350802	chr4_16009710_-	SINE	Alu	AluSx
CAediting_350803	chr4_16010596_-	SINE	Alu	AluJb
CAediting_350804	chr4_16010641_-	SINE	Alu	AluJb
CAediting_350805	chr4_16010719_-	SINE	Alu	AluJb
CAediting_350806	chr4_16010776_-	SINE	Alu	AluJb
CAediting_350807	chr4_16042033_-	SINE	Alu	AluJr
CAediting_350808	chr4_16042081_-	SINE	Alu	AluJr
CAediting_350809	chr4_16050478_-	SINE	Alu	AluJb
CAediting_350810	chr4_16052575_-	SINE	Alu	AluJb
CAediting_350811	chr4_16052606_-	SINE	Alu	AluJb
CAediting_350812	chr4_16052776_-	SINE	Alu	AluJb
CAediting_350813	chr4_16053981_-	SINE	Alu	AluSz
CAediting_350814	chr4_16053982_-	SINE	Alu	AluSz
CAediting_350815	chr4_16054088_-	SINE	Alu	AluSz
CAediting_350816	chr4_16059666_-	SINE	Alu	AluJo
CAediting_350817	chr4_16060465_-	SINE	Alu	AluJb
CAediting_350818	chr4_16062030_-	SINE	Alu	AluY

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RNA A-to-I editing events in the alternative splicing sites for PROM1

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000007062.10.PROM1.

Correlation between RNA A-to-I editing and PSI for ENSG00000007062.10.PROM1.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PROM1

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

STAD.CAediting_350757.ENSG00000007062.PROM1.png
Soverview

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Protein coding region RNA A-to-I editings for PROM1

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for PROM1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_748296	chr10_51299626_+	ENSG00000007062.10	ENST00000503884	hsa-miR-605-3p	15964369	15964375	7mer-m8	15964368	15964389	144	-18.75
CAediting_688081	chr9_63819627_+	ENSG00000007062.10	ENST00000505450	hsa-miR-4477b	15968436	15968443	8mer-1a	15968436	15968457	145	-12.8
CAediting_688081	chr9_63819627_+	ENSG00000007062.10	ENST00000508167	hsa-miR-4477b	15968436	15968443	8mer-1a	15968436	15968457	145	-12.8
CAediting_688081	chr9_63819627_+	ENSG00000007062.10	ENST00000510224	hsa-miR-4477b	15968436	15968443	8mer-1a	15968436	15968457	145	-12.8
CAediting_393	chr1_1167164_+	ENSG00000007062.10	ENST00000511153	hsa-miR-200b-3p	16009024	16009030	7mer-m8	16009023	16009044	142	-12.37
CAediting_1229415	chr17_67471547_+	ENSG00000007062.10	ENST00000503884	hsa-miR-548aa	15964311	15964318	8mer-1a	15964311	15964336	157	-14.82
CAediting_228905	chr2_188297554_+	ENSG00000007062.10	ENST00000505450	hsa-miR-561-3p	15969051	15969058	8mer-1a	15969051	15969071	143	-9.58
CAediting_604450	chr7_133034877_-	ENSG00000007062.10	ENST00000505450	hsa-miR-3654	15968466	15968473	8mer-1a	15968466	15968488	151	-22.9
CAediting_228905	chr2_188297554_+	ENSG00000007062.10	ENST00000508167	hsa-miR-561-3p	15969051	15969058	8mer-1a	15969051	15969071	143	-9.58
CAediting_604450	chr7_133034877_-	ENSG00000007062.10	ENST00000508167	hsa-miR-3654	15968466	15968473	8mer-1a	15968466	15968488	151	-22.9
CAediting_228905	chr2_188297554_+	ENSG00000007062.10	ENST00000510224	hsa-miR-561-3p	15969051	15969058	8mer-1a	15969051	15969071	143	-9.58
CAediting_604450	chr7_133034877_-	ENSG00000007062.10	ENST00000510224	hsa-miR-3654	15968466	15968473	8mer-1a	15968466	15968488	151	-22.9
CAediting_228905	chr2_188297554_+	ENSG00000007062.10	ENST00000511153	hsa-miR-561-3p	16025211	16025216	6mer	16025210	16025232	157	-22.21
CAediting_1351755	chr19_40282625_-	ENSG00000007062.10	ENST00000511153	hsa-miR-641	16006565	16006570	6mer	16006564	16006587	142	-16.7
CAediting_442554	chr5_154685830_+	ENSG00000007062.10	ENST00000511153	hsa-miR-1303	16006562	16006568	7mer-m8	16006561	16006582	166	-25.98

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for PROM1

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for PROM1

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
BRCA	CAediting_350735	chr4_15972367_-	0.00563408916194512	0.29612544243311	.	.	.	.
BRCA	CAediting_350751	chr4_15973325_-	0.00430995518261946	0.372627773639954	.	.	.	.

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Relation with cancer stages for PROM1

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for PROM1

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
STAD	CAediting_350760	chr4_15973390_-	0.0215068263977147	0.0481142	0.00686043

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RelatedDrugs for PROM1

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for PROM1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
PROM1	C0017636	Glioblastoma	3	CTD_human
PROM1	C0334588	Giant Cell Glioblastoma	3	CTD_human
PROM1	C1621958	Glioblastoma Multiforme	3	CTD_human
PROM1	C0339512	Bull's eye macular dystrophy	2	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
PROM1	C0007102	Malignant tumor of colon	1	CTD_human
PROM1	C0007621	Neoplastic Cell Transformation	1	CTD_human
PROM1	C0009375	Colonic Neoplasms	1	CTD_human
PROM1	C0009402	Colorectal Carcinoma	1	CTD_human
PROM1	C0009404	Colorectal Neoplasms	1	CTD_human
PROM1	C0041696	Unipolar Depression	1	PSYGENET
PROM1	C0042138	Uterine Neoplasms	1	CTD_human
PROM1	C0153567	Uterine Cancer	1	CTD_human
PROM1	C0206627	Mixed Tumor, Mullerian	1	CTD_human
PROM1	C0271093	Stargardt's disease	1	ORPHANET
PROM1	C1269683	Major Depressive Disorder	1	PSYGENET
PROM1	C1855465	STARGARDT DISEASE 1 (disorder)	1	ORPHANET
PROM1	C1863534	Stargardt disease 4	1	CTD_human;GENOMICS_ENGLAND;UNIPROT
PROM1	C2675210	CONE-ROD DYSTROPHY 12 (disorder)	1	CTD_human;GENOMICS_ENGLAND;UNIPROT
PROM1	C3489532	Cone-Rod Dystrophy 2	1	ORPHANET

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene